Pneumococcal meningitis causes accumulation of neurotoxic kynurenine metabolites in brain regions prone to injury

Neurobiology of Disease

Volumn 24, Issue 2, 2006, Pages 395-402

  Bellac, Caroline L ^a   Coimbra, Roney S ^a   Christen, Stephan ^a   Leib, Stephen L ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

3 Hydroxykynurenine; Apoptosis; Brain injury; Kynurenine pathway; Neuroinflammatory diseases; Neurotoxicity; Pneumococcal meningitis

Indexed keywords

3 HYDROXYANTHRANILIC ACID; 3 HYDROXYKYNURENINE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL MENINGITIS; BRAIN CORTEX; BRAIN INJURY; BRAIN REGION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HIPPOCAMPUS; METABOLITE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION;

3-HYDROXYANTHRANILIC ACID; ANIMALS; APOPTOSIS; BRAIN; DISEASE MODELS, ANIMAL; ENCEPHALITIS; ENZYME ACTIVATION; HIPPOCAMPUS; KYNURENINE; KYNURENINE 3-MONOOXYGENASE; MENINGITIS, PNEUMOCOCCAL; NERVE DEGENERATION; NEUROTOXINS; RATS; RATS, WISTAR; UP-REGULATION;

EID: 33749997196     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.07.014     Document Type: Article

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