메뉴 건너뛰기




Volumn 34, Issue 32, 2013, Pages 2566-2574

Activation of intestinal peroxisome proliferator-activated receptor-α increases high-density lipoprotein production

Author keywords

Dyslipidaemia; HDL; Intestine; PPAR

Indexed keywords

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; ABC TRANSPORTER A1; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CHOLESTEROL; FAT DROPLET; FENOFIBRATE; GFT 505; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84883155218     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehs227     Document Type: Article
Times cited : (47)

References (54)
  • 1
    • 0023029454 scopus 로고
    • Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study
    • DOI 10.1001/jama.256.20.2835
    • Castelli W, Garrison R, Wilson P, Abbott R, Kalousdian S, Kannel W. Incidence of coronary heart disease and lipoprotein cholesterol levels: the Framingham study. JAMA 1986;256:2835-2838. (Pubitemid 17178361)
    • (1986) Journal of the American Medical Association , vol.256 , Issue.20 , pp. 2835-2838
    • Castelli, W.P.1    Garrison, R.J.2    Wilson, P.W.F.3
  • 2
    • 48349134171 scopus 로고    scopus 로고
    • Effects of statins on HDL: A potential contribution to cardiovascular benefit
    • McTaggart F, Jones P. Effects of statins on HDL: a potential contribution to cardiovascular benefit. Cardiovasc Drugs Ther 2008;22:321-338.
    • (2008) Cardiovasc Drugs Ther , vol.22 , pp. 321-338
    • McTaggart, F.1    Jones, P.2
  • 5
    • 34548806574 scopus 로고    scopus 로고
    • Development and Physiological Regulation of Intestinal Lipid Absorption. I. Development of intestinal lipid absorption: Cellular events in chylomicron assembly and secretion
    • DOI 10.1152/ajpgi.00189.2007
    • Black D. Development and physiological regulation of intestinal lipid absorption. I. Development of intestinal lipid absorption: cellular events in chylo-micron assembly and secretion. Am J Physiol Gastrointest Liver Physiol 2007;293: G519-G524. (Pubitemid 47435377)
    • (2007) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.293 , Issue.3
    • Black, D.D.1
  • 6
    • 68349126817 scopus 로고    scopus 로고
    • Methods to assess impaired post-prandial metabolism and the impact for early detection of cardiovascular disease risk
    • Su J, Nzekwu M, Cabezas M, Redgrave T, Proctor S. Methods to assess impaired post-prandial metabolism and the impact for early detection of cardiovascular disease risk. Eur J Clin Invest 2009;39:741-754.
    • (2009) Eur J Clin Invest , vol.39 , pp. 741-754
    • Su, J.1    Nzekwu, M.2    Cabezas, M.3    Redgrave, T.4    Proctor, S.5
  • 7
    • 0017808239 scopus 로고
    • Rat intestine secretes discoid HDL
    • Green P, Tall A, Glickman R. Rat intestine secretes discoid HDL. J Clin Invest 1978; 61:528-534.
    • (1978) J Clin Invest , vol.61 , pp. 528-534
    • Green, P.1    Tall, A.2    Glickman, R.3
  • 10
    • 0018759682 scopus 로고
    • Apolipoprotein A-I synthesis and secretion by cultured human intestinal mucosa
    • DOI 10.1016/0026-0495(79)90179-3
    • Rachmilewitz D, Fainaru M. ApolipoproteinA-I synthesis and secretion by cultured human intestinal mucosa. Metab Clin Exp 1979;28:739-743. (Pubitemid 9226030)
    • (1979) Metabolism: Clinical and Experimental , vol.28 , Issue.7 , pp. 739-743
    • Rachmilewitz, D.1    Fainaru, M.2
  • 11
    • 0018265748 scopus 로고
    • HDL secretion from human intestinal tract
    • Johansson C, Rössner S, Walldius G. HDL secretion from human intestinal tract. Lancet 1978;8059:324-325.
    • (1978) Lancet , vol.8059 , pp. 324-325
    • Johansson, C.1    Rössner, S.2    Walldius, G.3
  • 13
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPARα in energy metabolism and vascular homeostasis
    • DOI 10.1172/JCI27989
    • Lefebvre P, Chinetti G, Fruchart J, Staels B. Sorting out the roles of PPAR-alpha in energy metabolism and vascular homeostasis. J Clin Invest 2006;116:571-580. (Pubitemid 43326861)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.-C.3    Staels, B.4
  • 14
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat
    • DOI 10.1210/en.137.1.354
    • Braissant O, Foufelle F, Scotto C, Dauça M, Wahli W. Differential expression of peroxisome proliferator-activated receptors: tissue distribution of PPAR-alpha,-beta, and-gamma in the adult rat. Endocrinology 1996;137:354-366. (Pubitemid 26005011)
    • (1996) Endocrinology , vol.137 , Issue.1 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 17
    • 0037339775 scopus 로고    scopus 로고
    • Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome
    • DOI 10.2337/diabetes.52.3.803
    • Watts G, Barrett P, Ji J, Serone A, Chan D, Croft K, Loehrer F, Johnson A. Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome. Diabetes 2003;52:803-811. (Pubitemid 36323589)
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 803-811
    • Watts, G.F.1    Barrett, P.H.R.2    Ji, J.3    Serone, A.P.4    Chan, D.C.5    Croft, K.D.6    Loehrer, F.7    Johnson, A.G.8
  • 19
    • 41349103062 scopus 로고    scopus 로고
    • Effects of fibrate drugs on expression of ABCA1 and HDL biogenesis in hepatocytes
    • DOI 10.1097/FJC.0b013e3181624b22, PII 0000534420080300000007
    • Hossain M, Tsujita M, Gonzalez F, Yokoyama S. Effects of fibrate drugs on expression of ABCA1 and HDL biogenesis in hepatocytes. J Cardiovasc Pharmacol 2008; 51:258-266. (Pubitemid 351450604)
    • (2008) Journal of Cardiovascular Pharmacology , vol.51 , Issue.3 , pp. 258-266
    • Hossain, M.A.1    Tsujita, M.2    Gonzalez, F.J.3    Yokoyama, S.4
  • 21
    • 68149098866 scopus 로고    scopus 로고
    • Identification of a physiologically relevant endogenous ligand for PPAR-alpha in liver
    • Chakravarthy M, Lodhi I, Yin L, Malapaka R, Xu H, Turk J, Semenkovich C. Identification of a physiologically relevant endogenous ligand for PPAR-alpha in liver. Cell 2009;138:476-488.
    • (2009) Cell , vol.138 , pp. 476-488
    • Chakravarthy, M.1    Lodhi, I.2    Yin, L.3    Malapaka, R.4    Xu, H.5    Turk, J.6    Semenkovich, C.7
  • 22
    • 0034616072 scopus 로고    scopus 로고
    • Oxidized phospholipids activate PPARα in a phospholipase A2-dependent manner
    • DOI 10.1016/S0014-5793(00)01364-8, PII S0014579300013648
    • Delerive P, Furman C, Teissier E, Fruchart J, Duriez P, Staels B. Oxidized phos-pholipids activate PPAR-alpha in a phospholipase A2-dependent manner. FEBS Lett 2000;471:34-38. (Pubitemid 30173288)
    • (2000) FEBS Letters , vol.471 , Issue.1 , pp. 34-38
    • Delerive, P.1    Furman, C.2    Teissier, E.3    Fruchart, J.-C.4    Duriez, P.5    Staels, B.6
  • 23
    • 0026577411 scopus 로고
    • Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat
    • Staels B, van Tol A, Andreu T, Auwerx J. Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat. Arterioscler Thromb 1992;12:286-294.
    • (1992) Arterioscler Thromb , vol.12 , pp. 286-294
    • Staels, B.1    Van Tol, A.2    Andreu, T.3    Auwerx, J.4
  • 25
    • 79960988152 scopus 로고    scopus 로고
    • Effects of the new dual PPAR-alpha/delta agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism
    • Cariou B, Zaïr Y, Staels B, Bruckert E. Effects of the new dual PPAR-alpha/delta agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism. Diabetes Care 2011;34:2008-2014.
    • (2011) Diabetes Care , vol.34 , pp. 2008-2014
    • Cariou, B.1    Zaïr, Y.2    Staels, B.3    Bruckert, E.4
  • 27
    • 12944259029 scopus 로고    scopus 로고
    • Lipid micelles stimulate the secretion of triglyceride-enriched apolipoprotein B48-containing lipoproteins by Caco-2 cells
    • DOI 10.1002/jcp.20173
    • Chateau D, Pauquai T, Delers F, Rousset M, Chambaz J, Demignot S. Lipid micelles stimulate the secretion of triglyceride-enriched apolipoprotein-B48- containing lipo-proteins by Caco-2 cells. J Cell Physiol 2005;202:767-776. (Pubitemid 40175852)
    • (2005) Journal of Cellular Physiology , vol.202 , Issue.3 , pp. 767-776
    • Chateau, D.1    Pauquai, T.2    Delers, F.3    Rousset, M.4    Chambaz, J.5    Demignot, S.6
  • 29
    • 0041935939 scopus 로고    scopus 로고
    • Bethesda, MD USA: US National Institutes of Health;
    • Rasband W. Imagej. Bethesda, MD, USA: US National Institutes of Health; 1997-2009 http://rsb.info.nih.gov/ij/.
    • (1997) Imagej
    • Rasband, W.1
  • 30
    • 24144476576 scopus 로고    scopus 로고
    • PPARα, but not PPARγ, activators decrease macrophage-laden atherosclerotic lesions in a nondiabetic mouse model of mixed dyslipidemia
    • DOI 10.1161/01.ATV.0000175756.56818.ee
    • Hennuyer N, Tailleux A, Torpier G, Mezdour H, Fruchart J, Staels B, Fiévet C. PPAR-alpha, but not PPAR-gamma, activators decrease macrophage-laden atherosclerotic lesions in a nondiabetic mouse model of mixed dyslipidemia. Arterios-cler Thromb Vasc Biol 2005;25:1897-1902. (Pubitemid 41243460)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.9 , pp. 1897-1902
    • Hennuyer, N.1    Tailleux, A.2    Torpier, G.3    Mezdour, H.4    Fruchart, J.-C.5    Staels, B.6    Fievet, C.7
  • 34
    • 34548182369 scopus 로고    scopus 로고
    • Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells
    • DOI 10.1194/jlr.M700029-JLR200
    • Field F, Watt K, Mathur S. Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in Caco-2 cells. J Lipid Res 2007;48:1735-1745. (Pubitemid 47311990)
    • (2007) Journal of Lipid Research , vol.48 , Issue.8 , pp. 1735-1745
    • Field, F.J.1    Watt, K.2    Mathur, S.N.3
  • 35
    • 73949130457 scopus 로고    scopus 로고
    • Differential association of adipophilin and TIP47 proteins with cytoplasmic lipid droplets in mouse enterocytes during dietary fat absorption
    • Lee B, Zhu J, Wolins N, Cheng J, Buhman K. Differential association of adipophilin and TIP47 proteins with cytoplasmic lipid droplets in mouse enterocytes during dietary fat absorption. Biochim Biophys Acta 2009;1791:1173-1180.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 1173-1180
    • Lee, B.1    Zhu, J.2    Wolins, N.3    Cheng, J.4    Buhman, K.5
  • 38
    • 77953229699 scopus 로고    scopus 로고
    • Relationship between cholesterol synthesis and intestinal absorption is associated with cardiovascular risk
    • Weingärtner O, Lütjohann D, Böhm M, Laufs U. Relationship between cholesterol synthesis and intestinal absorption is associated with cardiovascular risk. Atherosclerosis 2010;210:362-365.
    • (2010) Atherosclerosis , vol.210 , pp. 362-365
    • Weingärtner, O.1    Lütjohann, D.2    Böhm, M.3    Laufs, U.4
  • 39
    • 84859158546 scopus 로고    scopus 로고
    • Regulation of chylomicron production in humans
    • doi:10.1016/j.bbalip.2011.09.019
    • Xiao C, Lewis G. Regulation of chylomicron production in humans. Biochim Biophys Acta 2011;doi:10.1016/j.bbalip.2011.09.019.
    • (2011) Biochim Biophys Acta
    • Xiao, C.1    Lewis, G.2
  • 40
    • 33645076793 scopus 로고    scopus 로고
    • Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism
    • Fruchart J, Duriez P. Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism. Drugs Today 2006;42:39-64.
    • (2006) Drugs Today , vol.42 , pp. 39-64
    • Fruchart, J.1    Duriez, P.2
  • 41
    • 44849141405 scopus 로고    scopus 로고
    • Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men
    • Rigamonti E, Chinetti-Gbaguidi G, Staels B. Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men. Arterioscler Thromb Vasc Biol 2008;28:1050-1059.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1050-1059
    • Rigamonti, E.1    Chinetti-Gbaguidi, G.2    Staels, B.3
  • 43
    • 19344375593 scopus 로고    scopus 로고
    • Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome
    • DOI 10.1001/archinte.165.10.1154
    • Tenenbaum A, Motro M, Fisman E, Tanne D, Boyko V, Behar S. Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med 2005;165:1154-1160. (Pubitemid 40720740)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.10 , pp. 1154-1160
    • Tenenbaum, A.1    Motro, M.2    Fisman, E.Z.3    Tanne, D.4    Boyko, V.5    Behar, S.6
  • 44
    • 0034604225 scopus 로고    scopus 로고
    • Secondary prevention by raising HDL-cholesterol and reducing triglycerides in patients with coronary artery disease: The bezafibrate infarction prevention study
    • The BIP Study Group.
    • The BIP Study Group. Secondary prevention by raising HDL-cholesterol and reducing triglycerides in patients with coronary artery disease: the bezafibrate infarction prevention study. Circulation 2000;102:21-27.
    • (2000) Circulation , vol.102 , pp. 21-27
  • 45
    • 67649757581 scopus 로고    scopus 로고
    • Differentiated Caco-2 cells as an in-vitro model to evaluate de-novo apolipoproteinA-I production in the small intestine
    • Dullens S, Mensink R, Mariman E, Plat J. Differentiated Caco-2 cells as an in-vitro model to evaluate de-novo apolipoproteinA-I production in the small intestine. Eur J Gastroenterol Hepatol 2009;21:642-649.
    • (2009) Eur J Gastroenterol Hepatol , vol.21 , pp. 642-649
    • Dullens, S.1    Mensink, R.2    Mariman, E.3    Plat, J.4
  • 47
    • 35548953149 scopus 로고    scopus 로고
    • Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells
    • DOI 10.1016/j.bbrc.2007.10.028, PII S0006291X07021961
    • Pramfalk C, Angelin B, Eriksson M, Parini P. Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells. Biochem Biophys Res Commun 2007;364:402-409. (Pubitemid 350011075)
    • (2007) Biochemical and Biophysical Research Communications , vol.364 , Issue.2 , pp. 402-409
    • Pramfalk, C.1    Angelin, B.2    Eriksson, M.3    Parini, P.4
  • 48
    • 71749098785 scopus 로고    scopus 로고
    • Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 and adipose triglyceride lipase
    • Granneman J, Moore H, Krishnamoorthy R, Rathod M. Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 and adipose triglyceride lipase. J Biol Chem 2009;284:34538-34544.
    • (2009) J Biol Chem , vol.284 , pp. 34538-34544
    • Granneman, J.1    Moore, H.2    Krishnamoorthy, R.3    Rathod, M.4
  • 49
    • 77949538539 scopus 로고    scopus 로고
    • Arylacetamide deacetylase attenuates fatty-acid-induced triacylglycerol accumulation in rat hepatoma cells
    • Lo V, Erickson B, Thomason-Hughes M, Ko K, Dolinsky V, Nelson R, Lehner R. Arylacetamide deacetylase attenuates fatty-acid-induced triacylglycerol accumulation in rat hepatoma cells. J Lipid Res 2010;51:368-377.
    • (2010) J Lipid Res , vol.51 , pp. 368-377
    • Lo, V.1    Erickson, B.2    Thomason-Hughes, M.3    Ko, K.4    Dolinsky, V.5    Nelson, R.6    Lehner, R.7
  • 50
    • 35148858697 scopus 로고    scopus 로고
    • Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin M reduces hypertriglyceridemia through enhanced β-oxidation
    • DOI 10.1161/ATVBAHA.107.148429, PII 0004360520071000000019
    • Zhou Y, Abidi P, Kim A, Chen W, Huang T, Kraemer F, Liu J. Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin m reduces hypertriglyceride-mia through enhanced beta-oxidation. Arterioscler Thromb Vasc Biol 2007;27: 2198-2205. (Pubitemid 350287250)
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , Issue.10 , pp. 2198-2205
    • Zhou, Y.1    Abidi, P.2    Kim, A.3    Chen, W.4    Huang, T.-T.5    Kraemer, F.B.6    Liu, J.7
  • 51
    • 77951646726 scopus 로고    scopus 로고
    • Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: Results from the BACH (Biomarkers in Acute Heart Failure) trial
    • Kremastinos D, Hartmann O, von Haehling S, Bergmann A, Morgenthaler NG, Anker SD. Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial. J Am Coll Cardiol 2010;55:2062-2076.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2062-2076
    • Kremastinos, D.1    Hartmann, O.2    Von Haehling, S.3    Bergmann, A.4    Morgenthaler, N.G.5    Anker, S.D.6
  • 53
    • 72549097700 scopus 로고    scopus 로고
    • N-Terminal pro-B-type natriuretic peptide-guided treatment for chronic heart failure. Results from the BATTLE-SCARRED (NT-proBNP-Assisted Treatment to Lessen Serial Cardiac Readmissions and Death) trial
    • Lainchbury JG, Troughton RW, Strangman KM, Frampton KM, Pilbrow A, Yandle TG, Hamid AK, Nicholls G, Richards M. N-Terminal pro-B-type natriuretic peptide-guided treatment for chronic heart failure. Results from the BATTLE-SCARRED (NT-proBNP-Assisted Treatment To Lessen Serial Cardiac Readmissions and Death) trial. J Am Coll Cardiol 2009;55:53-60.
    • (2009) J Am Coll Cardiol , vol.55 , pp. 53-60
    • Lainchbury, J.G.1    Troughton, R.W.2    Strangman, K.M.3    Frampton, K.M.4    Pilbrow, A.5    Yandle, T.G.6    Hamid, A.K.7    Nicholls, G.8    Richards, M.9
  • 54
    • 68849114272 scopus 로고    scopus 로고
    • Biomarker-guided therapy in chronic heart failure: A meta-analysis of randomized controlled trials
    • Felker GM, Hasselblad V, Hernandez AF, O'Connor CM. Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials. Am Heart J 2009;158:422-430.
    • (2009) Am Heart J , vol.158 , pp. 422-430
    • Felker, G.M.1    Hasselblad, V.2    Hernandez, A.F.3    O'Connor, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.