Subtype-specific synaptic proteome alterations in sporadic creutzfeldt-jakob disease

Journal of Alzheimer's Disease

Volumn 37, Issue 1, 2013, Pages 51-61

  Gawinecka, Joanna ^a   Nowak, Martin ^a   Carimalo, Julie ^a   Cardone, Franco ^b   Asif, Abdul R ^a   Wemheuer, Wiebke M ^a   Schulz Schaeffer, Walter J ^a   Pocchiari, Maurizio ^b   Zerr, Inga ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

2D fluorescence difference gel electrophoresis (2D DIGE); Creutzfeldt Jakob disease; proteomics; sCJD; synapse; synaptic dysfunction

Indexed keywords

ALPHA CRYSTALLIN; ASPARTATE AMINOTRANSFERASE; BETA TUBULIN; BINDING PROTEIN; CALPHOBINDIN II; DIMETHYLARGININASE; ENOYL COENZYME A HYDRATASE; FERRITIN; FODRIN; FRUCTOSE BISPHOSPHATE ALDOLASE; GELSOLIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 90; MALATE DEHYDROGENASE; METHIONINE; N ETHYLMALEIMIDE SENSITIVE FACTOR; PEROXIREDOXIN 2; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PROTEIN 14 3 3; PROTEIN VARIANT; PROTEOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); VALINE;

AGED; ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CALCIUM METABOLISM; CELL METABOLISM; CELL STRUCTURE; CELL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MASS SPECTROMETRY; MITOCHONDRION; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; SPORADIC CREUTZFELDT JAKOB DISEASE; SYNAPSE; SYNAPTOSOME; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING;

AGED; CREUTZFELDT-JAKOB SYNDROME; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; FRONTAL LOBE; HUMANS; MALE; MIDDLE AGED; PROTEOME; SYNAPSES;

EID: 84883145997     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-130455     Document Type: Article

References (39)

1. Parchi P, Giese A, Capellari S, Brown P, Schulz-Schaeffer W, Windl O, Zerr I, Budka H, Kopp N, Piccardo P, Poser S, Rojiani A, Streichemberger N, Julien J, Vital C, Ghetti B, Gambetti P, Kretzschmar HA (1999) Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Ann Neurol 46, 224-233. (Pubitemid 29382879)
2. Gambetti P, Kong Q, Zou W, Parchi P, Chen SG (2003) Sporadic and familial CJD: Classification and characterisation. Br Med Bull 66, 213-239. (Pubitemid 37173504)
3. Clinton J, Forsyth C, Royston MC, Roberts GW (1993) Synaptic degeneration is the primary neuropathological feature in prion disease: A preliminary study. Neuroreport 4, 65-68. (Pubitemid 23066392)
4. Ferrer I, Puib B, Blanco R, Mart́i E (2000) Prion protein deposition and abnormal synaptic protein expression in the cerebellum in Creutzfeldt-Jakob disease. Neuroscience 97, 715-726. (Pubitemid 30332178)
5. Jeffrey M, Halliday WG, Bell J, Johnston AR, MacLeod NK, Ingham C, Sayers AR, Brown DA, Fraser JR (2000) Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus. Neuropathol Appl Neurobiol 26, 41-54. (Pubitemid 30145305)
6. Siskov́a Z, Sanyal NK, Orban A, O'Connor V, Perry VH (2010) Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice. Biochem Soc Trans 38, 471-475.
7. Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ 3rd, DeArmond S (2004) The neurodegeneration sequence in prion diseases: Evidence from functional, morphological and ultrastructural studies of the GABAergic system. J Neuropathol Exp Neurol 63, 882-899. (Pubitemid 39043694)
8. Brown P, Rohwer RG, Gajdusek DC (1986) Newer data on the inactivation of scrapie virus or Creutzfeldt-Jakob disease virus in brain tissue. J Infect Dis 153, 1145-1148. (Pubitemid 16086784)
9. Tateishi J, Tashima T, Kitamoto T (1991) Practical methods for chemical inactivation of Creutzfeldt-Jakob disease pathogen. Microbiol Immunol 35, 163-166.
10. Prusiner SB, Groth D, Serban A, Stahl N, Gabizon R (1993) Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proc Natl Acad Sci USA 90, 2793-2797. (Pubitemid 23113503)
11. Yao HL, Han J, Gao JM, Zhang J, Zhang BY, Guo YJ, Nie K, Gao C, Wang XF, Dong XP (2005) Comparative study of the effects of several chemical and physical treatments on the activity of protease resistance and infectivity of scrapie strain 263K. J Vet Med B Infect Dis Vet Public Health 52, 437-443. (Pubitemid 44922235)
12. Candiano G, Bruschi M, Musante L, Santucci L, Ghiggeri GM, Carnemolla B, Orecchia P, Zardi L, Righetti PG (2004) Blue silver: A very sensitive colloidal Coomassie G-250 staining for proteome analysis. Electrophoresis 25, 1327-1333. (Pubitemid 38801651)
13. Ramljak S, Asif AR, Armstrong VW, Wrede A, Groschup MH, Buschmann A, Schulz-SchaefferW, BodemerW, Zerr I (2008) Physiological role of the cellular prion protein (PrPc): Protein profiling study in two cell culture systems. J Proteome Res 7, 2681-2695.
14. Asif AR, Oellerich M, Amstrong VW, Gross U, Reichard U (2010) Analysis of the cellular Aspergillus fumigatus proteome that reacts with sera from rabbits developing an acquired immunityafter experimental aspergillosis. Electrophoresis 31, 1947-1958.
15. Guenther K, Deacon R, Perry VH, Rawlins JN (2001) Early behavioural changes in scrapie-affected mice and the influence of dapsone. Eur J Neurosci 14, 401-409. (Pubitemid 32777645)
16. Cunningham C, Deacon R,Wells H, Boche D,Waters S, Diniz CP, Scott H, Rawlins JN, Perry VH (2003) Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease. Eur J Neurosci 17, 2147-2155. (Pubitemid 36713975)
17. Chiesa R, Picardo P, Dossena S, Nowoslawski L, Roth KA, Ghetti B, Harris DA (2005) Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease. Proc Natl Acad Sci USA 102, 238-243. (Pubitemid 40094459)
18. Moreno JA, Mallucci GR (2010) Dysfunction and recovery of synapses in prion disease: Implications for neurodegeneration. Biochem Soc Trans 38, 482-487.
19. XiangW,Windl O,Westner IM, Neumann M, Zerr I, Lederer RM, Kretzschmar HA (2005) Cerebral gene expression profiles in sporadic Creutzfeldt-Jakob disease. Ann Neurol 58, 242-257. (Pubitemid 41098882)
20. Gawinecka J, Cardone F, Asif AR, De Pascalis A,Wemheuer WM, Schulz-Schaeffer WJ, Pocchiari M, Zerr I (2012) Sporadic Creutzfeldt-Jakob disease subtype-specific alterations of the brain proteome: Impact on Rab3a recycling. Proteomics 12, 3610-3620.
21. Novitskaya V, Makarava N, Sylvester I, Bronstein IB, Baskakov IV (2007) Amyloid fibrils of mammalian prion protein induce axonal degeneration in NTERA2-derived terminally differentiated neurons. J Neurochem 102, 398-407. (Pubitemid 47000598)
22. Wechsler A, Teichberg VI (1998) Brain spectrin binding to the NMDA receptor is regulated by phosphorylation, calcium and calmodulin. EMBO J 17, 3931-3939. (Pubitemid 28333979)
23. Morgado-Bernal I (2011) Learning and memory consolidation: Linking molecular and behavioral data. Neuroscience 176, 12-19.
24. Morel E, Fouquet S, Strup-Perrot C, Pichol Thievend C, Petit C, Loew D, Faussat AM, Yvernault L, Pinçon-Raymond M, Chambaz J, Rousset M, Thenet S, Clair C (2008) The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins. PLoS One 3, e3000.
25. Weiss E, Ramljak S, Asif AR, Ciesielczyk B, Schmitz M, Gawinecka J, Schulz-Schaeffer W, Behrens C, Zerr I (2010) Cellular prion protein overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: A proteomic study. Neuroscience 169, 1640-1650.
26. Zafar S, von Ahsen N, Oellerich M, Zerr I, Schulz-Schaeffer WJ, Armstrong VW, Asif AR (2011) Proteomics approach to identify the interacting partners of cellular prion protein and characterization of Rab7a interaction in neuronal cells. J Proteome Res 10, 3123-3135.
27. Han GA, Malintan NT, Collins BM, Meunier FA, Sugita S (2010) Munc18-1 as a key regulator of neurosecretion. J Neurochem 115, 1-10.
28. Hata Y, Slaughter CA, S̈udhof TC (1993) Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366, 347-351.
29. Sakurai T, Kaneko K, Okuno M, Wada K, Kashiyama T, Shimizu H, Akagi T, Hashikawa T, Nukina N (2008) Membrane microdomain switching: A regulatory mechanism of amyloid precursor protein processing. J Cell Biol 183, 339-352.
30. Baier M, Apelt J, Riemer C, G̈ultner S, Schwarz A, Bamme T, Burwinkel M, Schliebs R (2008) Prion infection of mice transgenic for human APPSwe: Increased accumulation of cortical formic acid extractable Abeta(1-42) and rapid scrapie disease development. Int J Dev Neurosci 26, 821-824.
31. Morales R, Estrada LD, Diaz-Espinoza R, Morales-Scheihing D, Jara MC, Castilla J, Soto C (2010) Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases. J Neurosci 30, 4528-4535.
32. Lopes JP, Oliveira CR, Agostinho P (2007) Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: Implications for Alzheimer's disease and prion-related encephalopathies. Cell Mol Neurobiol 27, 943-957.
33. Grimm S, Hoehn A, Davies KJ, Grune T (2011) Protein oxidative modifications in the ageing brain: Consequence for the onset of neurodegenerative disease. Free Radic Res 45, 73-88.
34. O'Donovan CN, Tobin D, Cotter TG (2001) Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells. J Biol Chem 276, 43516-43523.
35. Ferreiro E, Oliveria CR, Pereira CM (2008) The release of calcium from the endoplasmic reticulum induced by amyloidbeta and prion peptides activates the mitochondrial apoptotic pathway. Neurobiol Dis 30, 331-342.
36. Dehle FC, Ecroyd H, Musgrave IF, Carver JA (2010) BCrystallin inhibits the cell toxicity associated with amyloid fibril formation by ?-casein and the amyloid-peptide. Cell Stress Chaperones 15, 1013-1026.
37. Sun Y, Makarava N, Lee CI, Laksanalamai P, Robb FT, Baskakov IV (2008) Conformational stability of PrP amyloid fibrils controls their smallest possible fragment size. J Mol Biol 376, 1155-1167.
38. Carimalo J, Cronier S, Petit G, Peyrin JM, Boukhtouche F, Arbez N, Lemaigre-Dubreuil Y, Brugg B, Miquel MC (2005) Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection. Eur J Neurosci 21, 2311-2319. (Pubitemid 40813915)
39. Cronier S, Beringue V, Bellon A, Peyrin JM, Laude H (2007) Prion strain-and species-dependent effects of antiprion molecules in primary neuronal cultures. J Virol 81, 13794-13800. (Pubitemid 350247872)