Cerebral gene expression profiles in sporadic Creutzfeldt-Jakob disease

Annals of Neurology

Volumn 58, Issue 2, 2005, Pages 242-257

  Xiang, Wei ^a   Windl, Otto ^a,c   Westner, Ingo M ^a,d   Neumann, Manuela ^a   Zerr, Inga ^b   Lederer, Rosa M ^a   Kretzschmar, Hans A ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c VETERINARY LABORATORIES AGENCY   (United Kingdom)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALPHA TUBULIN; BETA1 INTEGRIN; CALBINDIN; CALMODULIN; CAVEOLIN 1; CD99 ANTIGEN; CYCLIN D1; DIPEPTIDYL PEPTIDASE I; DYNEIN ADENOSINE TRIPHOSPHATASE; GLIAL FIBRILLARY ACIDIC PROTEIN; GUANYLATE CYCLASE; HIPPOCALCIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSITOL TRISPHOSPHATE 3 KINASE; LIPOCORTIN 5; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; MESSENGER RNA; METALLOTHIONEIN; MOESIN; MYOSIN; NEUROFILAMENT PROTEIN; PDZ PROTEIN; PRION PROTEIN; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN P53; TUMOR NECROSIS FACTOR RECEPTOR; VILLIN; ZINC FINGER PROTEIN;

ADULT; AGED; AGING; ARTICLE; CELL ADHESION; CELL CYCLE; CELL DEATH; CLUSTER ANALYSIS; COMPUTER PROGRAM; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; CYTOSKELETON; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE FUNCTION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; ION TRANSPORT; LIPID METABOLISM; METAL BINDING; NERVOUS SYSTEM DEVELOPMENT; NUCLEIC ACID METABOLISM; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; STRESS; SYNAPSE; UNINDEXED SEQUENCE; WESTERN BLOTTING;

AGED; CEREBRAL CORTEX; CREUTZFELDT-JAKOB SYNDROME; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 23244439055     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20551     Document Type: Article

References (50)

1. Collinge J, Sidle KC, Meads J, et al. Molecular analysis of priori strain variation and the aetiology of 'new variant' CJD. Nature 1996;383:685-690.
2. Windl O, Giese A, Schulz-Schaeffer W, et al. Molecular genetics of human prion diseases in Germany. Hum Genet 1999; 105:244-252.
3. Prusiner SB. Prions. Proc Natl Acad Sci U S A 1998;95: 13363-13383.
4. Kretzschmar HA, Ironside JW, DeArmond SJ, et al. Diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Arch Neurol 1996;53:913-920.
5. Palmer MS, Dryden AJ, Hughes JT, et al. Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease. Nature 1991;352:340-342.
6. Windl O, Dempster M, Estibeiro JP, et al. Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene. Hum Genet 1996;98:259-264.
7. Parchi P, Giese A, Capellari S, et al. Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Ann Neurol 1999;46:224-233.
8. Notari S, Capellari S, Giese A, et al. Effects of different experimental conditions on the PrPSc core generated by protease digestion: implications for strain typing and molecular classification of CJD. J Biol Chem 2004;279:16797-16804.
9. Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000;403:503-511.
10. Golub TR, Slonim DK, Tamayo P, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-537.
11. Xiang W, Windl O, Wunsch G, et al. Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology. J Virol 2004;78: 11051-11060.
12. Booth S, Bowman C, Baumgartner R, et al. Identification of central nervous system genes involved in the host response to the scrapie agent during preclinical and clinical infection. J Gen Virol 2004;85:3459-3471.
13. Riemer C, Neidhold S, Burwinkel M, et al. Gene expression profiling of scrapie-infected brain tissue. Biochem Biophys Res Commun 2004;323:556-564.
14. Mimics K, Middleton FA, Marquez A, et al. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron 2000;28:53-67.
15. Pongrac J, Middleton FA, Lewis DA, et al. Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders. Neurochem Res 2002;27:1049-1063.
16. Tkachev D, Mimmack ML, Ryan MM, et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 2003; 362:798-805.
17. Colangelo V, Schurr J, Ball MJ, et al. Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor downregulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 2002;70:462-473.
18. Lu T, Pan Y, Kao SY, et al. Gene regulation and DNA damage in the ageing human brain. Nature 2004;429:883-891.
19. Buesa C, Maes T, Subirada F, et al. DNA chip technology in brain banks: confronting a degrading world. J Neuropathol Exp Neurol 2004;63:1003-1014.
20. Li C, Wong WH. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A 2001;98:31-36.
21. Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001;98:5116-5121.
22. Eisen MB, Spellman PT, Brown PO, et al. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 1998:95:14863-14868.
23. Liu G, Loraine AE, Shigeta R, et al. NetAffx: Affymetrix probe-sets and annotations. Nucleic Acids Res 2003;31:82-86.
24. Ashburner M, Ball CA, Blake JA, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 2000;25:25-29.
25. Dandoy-Dron F, Guillo F, Benboudjema L, et al. Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J Biol Chem 1998;273:7691-7697.
26. Kawashima T, Doh-ura K, Torisu M, et al. Differential expression of metallothioneins in human prion diseases. Dement Geriatr Cogn Disord 2000;11:251-262.
27. Mutch DM, Berger A, Mansourian R, et al. Microarray data analysis: a practical approach for selecting differentially expressed genes. Genome Biol 2001;2:PREPRINT0009.
28. Martin H, Rostas J, Patel Y, et al. Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies. J Neurochem 1994;63:2259-2265.
29. Otto M, Stein H, Szudra A, et al. S-100 protein concentration in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. J Neurol 1997;244:566-570.
30. Ferrer I, Rivera R, Blanco R, et al. Expression of proteins linked to exocytosis and neurotransmission in patients with Creutzfeldt-Jakob disease. Neurobiol Dis 1999;6:92-100.
31. Kordek R, Liberski PP, Yanagihara R, et al. Molecular analysis of priori protein (PrP) and glial fibrillary acidic protein (GFAP) transcripts in experimental Creutzfeldt-Jakob disease in mice. Acta Neurobiol Exp (Wars) 1997;57:85-90.
32. Giese A, Brown DR, Groschup MH, et al. Role of microglia in neuronal cell death in prion disease. Brain Pathol 1998;8: 449-457.
33. Forloni G, Bugiani O, Tagliavini F, et al. Apoptosis-mediated neurotoxicity induced by beta-amyloid and PrP fragments. Mol Chem Neuropathol 1996;28:163-171.
34. Hamdane M, Delobel P, Sambo AV, et al. Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis? Biochem Pharmacol 2003;66:1619-1625.
35. Zerial M, McBride H. Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2001;2:107-117.
36. Beranger F, Mange A, Goud B, et al. Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells. J Biol Chem 2002;277:38972-38977.
37. Kaneko K, Vey M, Scott M, et al. COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform. Proc Natl Acad Sci U S A 1997;94:2333-2338.
38. Vey M, Pilkuhn S, Wille H, et al. Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proc Natl Acad Sci U S A 1996;93:14945-14949.
39. Mouillet-Richard S, Ermonval M, Chebassier C, et al. Signal transduction through prion protein. Science 2000;289:1925-1928.
40. Nakanishi H. Neuronal and microglial cathepsins in aging and age-related diseases. Ageing Res Rev 2003;2:367-381.
41. Brown AR, Webb J, Rebus S, et al. Identification of upregulated genes by array analysis in scrapie-infected mouse brains. Neuropathol Appl Neurobiol 2004;30:555-567.
42. Sanchez JC, Guillaume E, Lescuyer P, et al. Cystatin C as a potential cerebrospinal fluid marker for the diagnosis of Creutzfeldt-Jakob disease. Proteomics 2004;4:2229-2233.
43. Deng A, Irizarry MC, Nitsch RM, et al. Elevation of cystatin C in susceptible neurons in Alzheimer's disease. Am J Pathol 2001;159:1061-1068.
44. Vincent B, Paitel E, Saftig P, et al. The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J Biol Chem 2001;276:37743-37746.
45. Herms J, Tings T, Gall S, et al. Evidence of presynaptic location and function of the prion protein. J Neurosci 1999;19: 8866-8875.
46. Sales N, Rodolfo K, Hassig R, et al. Cellular prion protein localization in rodent and primate brain. Eur J Neurosci 1998; 10:2464-2471.
47. Jeffrey M, Halliday WG, Bell J, et al. Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus. Neuropathol Appl Neurobiol 2000;26:41-54.
48. Wiltfang J, Otto M, Baxter HC, et al. Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. J Neurochem 1999;73:2485-2490.
49. Baxter HC, Liu WG, Forster JL, et al. Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain. Neuroscience 2002;109:5-14.
50. Hur K, Kim JI, Choi SI, et al. The pathogenic mechanisms of prion diseases. Mech Ageing Dev 2002;123:1637-1647.