메뉴 건너뛰기




Volumn 115, Issue 1, 2010, Pages 1-10

Munc18-1 as a key regulator of neurosecretion

Author keywords

dense core vesicles; exocytosis; soluble N ethylmaleimide sensitive factor attachment protein receptors; synaptic vesicles; syntaxin; trafficking

Indexed keywords

PROTEIN; PROTEIN MUNC 18-1; SNARE PROTEIN; SYNTAXIN 1; UNCLASSIFIED DRUG; MUNC18 PROTEIN; PROTEIN BINDING;

EID: 77956578675     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06900.x     Document Type: Review
Times cited : (66)

References (65)
  • 1
    • 39449127989 scopus 로고    scopus 로고
    • Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells
    • Arunachalam L., Han L., Tassew N. G. et al. (2008) Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells. Mol. Biol. Cell 19, 722 734.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 722-734
    • Arunachalam, L.1    Han, L.2    Tassew, N.G.3
  • 2
    • 56049105171 scopus 로고    scopus 로고
    • A random mutagenesis approach to isolate dominant-negative yeast sec1 mutants reveals a functional role for domain 3a in yeast and mammalian Sec1/Munc18 proteins
    • Boyd A., Ciufo L. F., Barclay J. W., Graham M. E., Haynes L. P., Doherty M. K., Riesen M., Burgoyne R. D. Morgan A. (2008) A random mutagenesis approach to isolate dominant-negative yeast sec1 mutants reveals a functional role for domain 3a in yeast and mammalian Sec1/Munc18 proteins. Genetics 180, 165 178.
    • (2008) Genetics , vol.180 , pp. 165-178
    • Boyd, A.1    Ciufo, L.F.2    Barclay, J.W.3    Graham, M.E.4    Haynes, L.P.5    Doherty, M.K.6    Riesen, M.7    Burgoyne, R.D.8    Morgan, A.9
  • 3
    • 0037112932 scopus 로고    scopus 로고
    • Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p
    • Bracher A. Weissenhorn W. (2002) Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p. EMBO J. 21, 6114 6124.
    • (2002) EMBO J. , vol.21 , pp. 6114-6124
    • Bracher, A.1    Weissenhorn, W.2
  • 4
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. (1974) The genetics of Caenorhabditis elegans. Genetics 77, 71 94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 5
    • 33947657322 scopus 로고    scopus 로고
    • Membrane trafficking: Three steps to fusion
    • Burgoyne R. D. Morgan A. (2007) Membrane trafficking: three steps to fusion. Curr. Biol. 17, R255 R258.
    • (2007) Curr. Biol. , vol.17
    • Burgoyne, R.D.1    Morgan, A.2
  • 6
    • 41949130893 scopus 로고    scopus 로고
    • Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide
    • Burkhardt P., Hattendorf D. A., Weis W. I. Fasshauer D. (2008) Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide. EMBO J. 27, 923 933.
    • (2008) EMBO J. , vol.27 , pp. 923-933
    • Burkhardt, P.1    Hattendorf, D.A.2    Weis, W.I.3    Fasshauer, D.4
  • 10
    • 77951729758 scopus 로고    scopus 로고
    • Single-vesicle fusion assay reveals Munc18-1 binding to the SNARE core is sufficient for stimulating membrane fusion
    • Diao J., Su Z., Lu X., Yoon T. Y., Shin Y. K. Ha T. (2010) Single-vesicle fusion assay reveals Munc18-1 binding to the SNARE core is sufficient for stimulating membrane fusion. ACS Chem. Neurosci. 1, 168 174.
    • (2010) ACS Chem. Neurosci. , vol.1 , pp. 168-174
    • Diao, J.1    Su, Z.2    Lu, X.3    Yoon, T.Y.4    Shin, Y.K.5    Ha, T.6
  • 15
    • 51749100843 scopus 로고    scopus 로고
    • Conformational switch of syntaxin-1 controls synaptic vesicle fusion
    • Gerber S. H., Rah J. C., Min S. W. et al. (2008) Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Science 321, 1507 1510.
    • (2008) Science , vol.321 , pp. 1507-1510
    • Gerber, S.H.1    Rah, J.C.2    Min, S.W.3
  • 17
    • 0030021851 scopus 로고    scopus 로고
    • The Sec1 family: A novel family of proteins involved in synaptic transmission and general secretion
    • Halachmi N. Lev Z. (1996) The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion. J. Neurochem. 66, 889 897.
    • (1996) J. Neurochem. , vol.66 , pp. 889-897
    • Halachmi, N.1    Lev, Z.2
  • 18
    • 73949143978 scopus 로고    scopus 로고
    • Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells
    • Han L., Jiang T., Han G. A. et al. (2009) Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells. Mol. Biol. Cell 20, 4962 4975.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4962-4975
    • Han, L.1    Jiang, T.2    Han, G.A.3
  • 19
    • 0027938531 scopus 로고
    • Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission
    • Harrison S. D., Broadie K., van de Goor J. Rubin G. M. (1994) Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission. Neuron 13, 555 566.
    • (1994) Neuron , vol.13 , pp. 555-566
    • Harrison, S.D.1    Broadie, K.2    Van De Goor, J.3    Rubin, G.M.4
  • 20
    • 0028998826 scopus 로고
    • A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic
    • Hata Y. Südhof T. C. (1995) A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. J. Biol. Chem. 270, 13022 13028.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13022-13028
    • Hata, Y.1    Südhof, T.C.2
  • 21
    • 0027364502 scopus 로고
    • Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
    • Hata Y., Slaughter C. A. Südhof T. C. (1993) Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366, 347 351.
    • (1993) Nature , vol.366 , pp. 347-351
    • Hata, Y.1    Slaughter, C.A.2    Südhof, T.C.3
  • 22
    • 0026582816 scopus 로고
    • The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans
    • Hosono R., Hekimi S., Kamiya Y., Sassa T., Murakami S., Nishiwaki K., Miwa J., Taketo A. Kodaira K. I. (1992) The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans. J. Neurochem. 58, 1517 1525.
    • (1992) J. Neurochem. , vol.58 , pp. 1517-1525
    • Hosono, R.1    Hekimi, S.2    Kamiya, Y.3    Sassa, T.4    Murakami, S.5    Nishiwaki, K.6    Miwa, J.7    Taketo, A.8    Kodaira, K.I.9
  • 23
    • 34547483062 scopus 로고    scopus 로고
    • Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins
    • Hu S. H., Latham C. F., Gee C. L., James D. E. Martin J. L. (2007) Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins. Proc. Natl Acad. Sci. USA 104, 8773 8778.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 8773-8778
    • Hu, S.H.1    Latham, C.F.2    Gee, C.L.3    James, D.E.4    Martin, J.L.5
  • 24
    • 59849095529 scopus 로고    scopus 로고
    • Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans
    • Johnson J. R., Ferdek P., Lian L. Y., Barclay J. W., Burgoyne R. D. Morgan A. (2009) Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans. Biochem. J. 418, 73 80.
    • (2009) Biochem. J. , vol.418 , pp. 73-80
    • Johnson, J.R.1    Ferdek, P.2    Lian, L.Y.3    Barclay, J.W.4    Burgoyne, R.D.5    Morgan, A.6
  • 25
    • 0028934796 scopus 로고
    • A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells
    • Katagiri H., Terasaki J., Murata T. et al. (1995) A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells. J. Biol. Chem. 270, 4963 4966.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4963-4966
    • Katagiri, H.1    Terasaki, J.2    Murata, T.3
  • 26
    • 0347091328 scopus 로고    scopus 로고
    • Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3
    • Kauppi M., Wohlfahrt G. Olkkonen V. M. (2002) Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3. J. Biol. Chem. 277, 43973 43979.
    • (2002) J. Biol. Chem. , vol.277 , pp. 43973-43979
    • Kauppi, M.1    Wohlfahrt, G.2    Olkkonen, V.M.3
  • 27
    • 36049049393 scopus 로고    scopus 로고
    • Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus
    • Khvotchev M., Dulubova I., Sun J., Dai H., Rizo J. Südhof T. C. (2007) Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus. J. Neurosci. 27, 12147 12155.
    • (2007) J. Neurosci. , vol.27 , pp. 12147-12155
    • Khvotchev, M.1    Dulubova, I.2    Sun, J.3    Dai, H.4    Rizo, J.5    Südhof, T.C.6
  • 28
    • 34447626621 scopus 로고    scopus 로고
    • Munc18a: Munc-y business in mediating exocytosis
    • Latham C. F. Meunier F. A. (2007) Munc18a: Munc-y business in mediating exocytosis. Int. J. Biochem. Cell Biol. 39, 1576 1581.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 1576-1581
    • Latham, C.F.1    Meunier, F.A.2
  • 29
    • 33748568111 scopus 로고    scopus 로고
    • Molecular dissection of the Munc18c/syntaxin4 interaction: Implications for regulation of membrane trafficking
    • Latham C. F., Lopez J. A., Hu S. H. et al. (2006) Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking. Traffic 7, 1408 1419.
    • (2006) Traffic , vol.7 , pp. 1408-1419
    • Latham, C.F.1    Lopez, J.A.2    Hu, S.H.3
  • 30
    • 33847721513 scopus 로고    scopus 로고
    • Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a
    • Latham C. F., Osborne S. L., Cryle M. J. Meunier F. A. (2007) Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a. J. Neurochem. 100, 1543 1554.
    • (2007) J. Neurochem. , vol.100 , pp. 1543-1554
    • Latham, C.F.1    Osborne, S.L.2    Cryle, M.J.3    Meunier, F.A.4
  • 32
    • 0041806509 scopus 로고    scopus 로고
    • A dual mechanism controlling the localization and function of exocytic v-SNAREs
    • Martinez-Arca S., Rudge R., Vacca M. et al. (2003) A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc. Natl Acad. Sci. USA 100, 9011 9016.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 9011-9016
    • Martinez-Arca, S.1    Rudge, R.2    Vacca, M.3
  • 33
    • 55549102680 scopus 로고    scopus 로고
    • UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin
    • McEwen J. M. Kaplan J. M. (2008) UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin. Mol. Biol. Cell 19, 3836 3846.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3836-3846
    • McEwen, J.M.1    Kaplan, J.M.2
  • 34
    • 38349018454 scopus 로고    scopus 로고
    • Munc18-1 prevents the formation of ectopic SNARE complexes in living cells
    • Medine C. N., Rickman C., Chamberlain L. H. Duncan R. R. (2007) Munc18-1 prevents the formation of ectopic SNARE complexes in living cells. J. Cell Sci. 120, 4407 4415.
    • (2007) J. Cell Sci. , vol.120 , pp. 4407-4415
    • Medine, C.N.1    Rickman, C.2    Chamberlain, L.H.3    Duncan, R.R.4
  • 35
    • 0034704771 scopus 로고    scopus 로고
    • Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
    • Misura K. M., Scheller R. H. Weis W. I. (2000) Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex. Nature 404, 355 362.
    • (2000) Nature , vol.404 , pp. 355-362
    • Misura, K.M.1    Scheller, R.H.2    Weis, W.I.3
  • 36
    • 0000756130 scopus 로고
    • Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae
    • Novick P. Schekman R. (1979) Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 76, 1858 1862.
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , pp. 1858-1862
    • Novick, P.1    Schekman, R.2
  • 37
    • 0018930046 scopus 로고
    • Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway
    • Novick P., Field C. Schekman R. (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21, 205 215.
    • (1980) Cell , vol.21 , pp. 205-215
    • Novick, P.1    Field, C.2    Schekman, R.3
  • 39
    • 0035913332 scopus 로고    scopus 로고
    • An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
    • Richmond J. E., Weimer R. M. Jorgensen E. M. (2001) An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412, 338 341.
    • (2001) Nature , vol.412 , pp. 338-341
    • Richmond, J.E.1    Weimer, R.M.2    Jorgensen, E.M.3
  • 40
    • 77950484580 scopus 로고    scopus 로고
    • Munc18/Syntaxin interaction kinetics control secretory vesicle dynamics
    • Rickman C. Duncan R. R. (2010) Munc18/Syntaxin interaction kinetics control secretory vesicle dynamics. J. Biol. Chem. 285, 3965 3972.
    • (2010) J. Biol. Chem. , vol.285 , pp. 3965-3972
    • Rickman, C.1    Duncan, R.R.2
  • 41
    • 0347683439 scopus 로고    scopus 로고
    • High affinity interaction of syntaxin and SNAP-25 on the plasma membrane is abolished by botulinum toxin e
    • Rickman C., Meunier F. A., Binz T. Davletov B. (2004) High affinity interaction of syntaxin and SNAP-25 on the plasma membrane is abolished by botulinum toxin E. J. Biol. Chem. 279, 644 651.
    • (2004) J. Biol. Chem. , vol.279 , pp. 644-651
    • Rickman, C.1    Meunier, F.A.2    Binz, T.3    Davletov, B.4
  • 42
    • 34249689155 scopus 로고    scopus 로고
    • Functionally and spatially distinct modes of Munc18-syntaxin 1 interaction
    • Rickman C., Medine C. N., Bergmann A. Duncan R. R. (2007) Functionally and spatially distinct modes of Munc18-syntaxin 1 interaction. J. Biol. Chem. 282, 12097 12103.
    • (2007) J. Biol. Chem. , vol.282 , pp. 12097-12103
    • Rickman, C.1    Medine, C.N.2    Bergmann, A.3    Duncan, R.R.4
  • 44
    • 0031669173 scopus 로고    scopus 로고
    • Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells
    • Riento K., Galli T., Jansson S., Ehnholm C., Lehtonen E. Olkkonen V. M. (1998) Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells. J. Cell Sci. 111, 2681 2688.
    • (1998) J. Cell Sci. , vol.111 , pp. 2681-2688
    • Riento, K.1    Galli, T.2    Jansson, S.3    Ehnholm, C.4    Lehtonen, E.5    Olkkonen, V.M.6
  • 45
    • 0034607845 scopus 로고    scopus 로고
    • Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells
    • Riento K., Kauppi M., Keranen S. Olkkonen V. M. (2000) Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells. J. Biol. Chem. 275, 13476 13483.
    • (2000) J. Biol. Chem. , vol.275 , pp. 13476-13483
    • Riento, K.1    Kauppi, M.2    Keranen, S.3    Olkkonen, V.M.4
  • 46
    • 0036673069 scopus 로고    scopus 로고
    • Snares and Munc18 in synaptic vesicle fusion
    • Rizo J. Sudhof T. C. (2002) Snares and Munc18 in synaptic vesicle fusion. Nat. Rev. Neurosci. 3, 641 653.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 641-653
    • Rizo, J.1    Sudhof, T.C.2
  • 47
    • 58149361168 scopus 로고    scopus 로고
    • Munc18a scaffolds SNARE assembly to promote membrane fusion
    • Rodkey T. L., Liu S., Barry M. McNew J. A. (2008) Munc18a scaffolds SNARE assembly to promote membrane fusion. Mol. Biol. Cell 19, 5422 5434.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 5422-5434
    • Rodkey, T.L.1    Liu, S.2    Barry, M.3    McNew, J.A.4
  • 48
    • 0032775945 scopus 로고    scopus 로고
    • Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: Prevention by rbSEC1
    • Rowe J., Corradi N., Malosio M. L., Taverna E., Halban P., Meldolesi J. Rosa P. (1999) Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1. J. Cell Sci. 112, 1865 1877.
    • (1999) J. Cell Sci. , vol.112 , pp. 1865-1877
    • Rowe, J.1    Corradi, N.2    Malosio, M.L.3    Taverna, E.4    Halban, P.5    Meldolesi, J.6    Rosa, P.7
  • 49
    • 0034773037 scopus 로고    scopus 로고
    • Syntaxin 1A is delivered to the apical and basolateral domains of epithelial cells: The role of Munc-18 proteins
    • Rowe J., Calegari F., Taverna E., Longhi R. Rosa P. (2001) Syntaxin 1A is delivered to the apical and basolateral domains of epithelial cells: the role of Munc-18 proteins. J. Cell Sci. 114, 3323 3332.
    • (2001) J. Cell Sci. , vol.114 , pp. 3323-3332
    • Rowe, J.1    Calegari, F.2    Taverna, E.3    Longhi, R.4    Rosa, P.5
  • 50
    • 0031019926 scopus 로고    scopus 로고
    • Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses
    • Schiavo G., Stenbeck G., Rothman J. E. Sollner T. H. (1997) Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc. Natl Acad. Sci. USA 94, 997 1001.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 997-1001
    • Schiavo, G.1    Stenbeck, G.2    Rothman, J.E.3    Sollner, T.H.4
  • 51
    • 33845987734 scopus 로고    scopus 로고
    • Selective activation of cognate SNAREpins by Sec1/Munc18 proteins
    • Shen J., Tareste D. C., Paumet F., Rothman J. E. Melia T. J. (2007) Selective activation of cognate SNAREpins by Sec1/Munc18 proteins. Cell 128, 183 195.
    • (2007) Cell , vol.128 , pp. 183-195
    • Shen, J.1    Tareste, D.C.2    Paumet, F.3    Rothman, J.E.4    Melia, T.J.5
  • 52
    • 0038107577 scopus 로고    scopus 로고
    • Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23
    • Sorensen J. B., Nagy G., Varoqueaux F., Nehring R. B., Brose N., Wilson M. C. Neher E. (2003) Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell 114, 75 86.
    • (2003) Cell , vol.114 , pp. 75-86
    • Sorensen, J.B.1    Nagy, G.2    Varoqueaux, F.3    Nehring, R.B.4    Brose, N.5    Wilson, M.C.6    Neher, E.7
  • 53
    • 58849092285 scopus 로고    scopus 로고
    • Membrane fusion: Grappling with SNARE and SM proteins
    • Südhof T. C. Rothman J. E. (2009) Membrane fusion: grappling with SNARE and SM proteins. Science 323, 474 477.
    • (2009) Science , vol.323 , pp. 474-477
    • Südhof, T.C.1    Rothman, J.E.2
  • 54
    • 0032584609 scopus 로고    scopus 로고
    • Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes
    • Tamori Y., Kawanishi M., Niki T., Shinoda H., Araki S., Okazawa H. Kasuga M. (1998) Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes. J. Biol. Chem. 273, 19740 19746.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19740-19746
    • Tamori, Y.1    Kawanishi, M.2    Niki, T.3    Shinoda, H.4    Araki, S.5    Okazawa, H.6    Kasuga, M.7
  • 55
    • 40649084835 scopus 로고    scopus 로고
    • SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
    • Tareste D., Shen J., Melia T. J. Rothman J. E. (2008) SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes. Proc. Natl Acad. Sci. USA 105, 2380 2385.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 2380-2385
    • Tareste, D.1    Shen, J.2    Melia, T.J.3    Rothman, J.E.4
  • 56
    • 0028924613 scopus 로고
    • Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues
    • Tellam J. T., McIntosh S. James D. E. (1995) Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. J. Biol. Chem. 270, 5857 5863.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5857-5863
    • Tellam, J.T.1    McIntosh, S.2    James, D.E.3
  • 57
    • 0030969764 scopus 로고    scopus 로고
    • Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes: Putative role in insulin-dependent movement of GLUT-4
    • Tellam J. T., Macaulay S. L., McIntosh S., Hewish D. R., Ward C. W. James D. E. (1997) Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes: putative role in insulin-dependent movement of GLUT-4. J. Biol. Chem. 272, 6179 6186.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6179-6186
    • Tellam, J.T.1    MacAulay, S.L.2    McIntosh, S.3    Hewish, D.R.4    Ward, C.W.5    James, D.E.6
  • 58
    • 35748984692 scopus 로고    scopus 로고
    • Munc18-1 in secretion: Lonely Munc joins SNARE team and takes control
    • Toonen R. F. Verhage M. (2007) Munc18-1 in secretion: lonely Munc joins SNARE team and takes control. Trends Neurosci. 30, 564 572.
    • (2007) Trends Neurosci. , vol.30 , pp. 564-572
    • Toonen, R.F.1    Verhage, M.2
  • 60
    • 0034603030 scopus 로고    scopus 로고
    • Synaptic assembly of the brain in the absence of neurotransmitter secretion
    • Verhage M., Maia A. S., Plomp J. J. et al. (2000) Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287, 864 869.
    • (2000) Science , vol.287 , pp. 864-869
    • Verhage, M.1    Maia, A.S.2    Plomp, J.J.3
  • 61
    • 0035949679 scopus 로고    scopus 로고
    • Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin i
    • Voets T., Moser T., Lund P. E., Chow R. H., Geppert M., Südhof T. C. Neher E. (2001a) Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I. Proc. Natl Acad. Sci. USA 98, 11680 11685.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 11680-11685
    • Voets, T.1    Moser, T.2    Lund, P.E.3    Chow, R.H.4    Geppert, M.5    Südhof, T.C.6    Neher, E.7
  • 64
    • 77749298991 scopus 로고    scopus 로고
    • Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle
    • Xu Y., Su L. Rizo J. (2010) Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle. Biochemistry 49, 1568 1576.
    • (2010) Biochemistry , vol.49 , pp. 1568-1576
    • Xu, Y.1    Su, L.2    Rizo, J.3
  • 65
    • 33750241320 scopus 로고    scopus 로고
    • Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes
    • Zilly F. E., Sorensen J. B., Jahn R. Lang T. (2006) Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes. PLoS Biol. 4, e330.
    • (2006) PLoS Biol. , vol.4 , pp. 330
    • Zilly, F.E.1    Sorensen, J.B.2    Jahn, R.3    Lang, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.