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Volumn 19, Issue 33, 2013, Pages 5840-5849

Emerging anti-inflammatory therapies for atherosclerosis

Author keywords

Atherosclerosis; Colchicine; Coronary disease; Inflammation; Interleukin 1; Leukotriene; P selectin; Serpins; Tumor Necrosis Factor alpha

Indexed keywords

ADALIMUMAB; ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; ATRELEUTON; CANAKINUMAB; CERTOLIZUMAB PEGOL; COLCHICINE; CREATINE KINASE MB; ETANERCEPT; FIBROBLAST GROWTH FACTOR; FLUORODEOXYGLUCOSE F 18; GEVOKIZUMAB; GOLIMUMAB; GROWTH DIFFERENTIATION FACTOR 15; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INCLACUMAB; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 6; LEUKOTRIENE; MATRIX METALLOPROTEINASE; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN; PLACEBO; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SERINE PROTEINASE INHIBITOR; SERP 1; TOCILIZUMAB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84883141104     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/13816128113199990351     Document Type: Review
Times cited : (20)

References (128)
  • 1
    • 0017668208 scopus 로고
    • Cellular mechanisms for lipid deposition in atherosclerosis (first of two parts)
    • Small DM. Cellular mechanisms for lipid deposition in atherosclerosis (first of two parts). N Engl J Med 1977; 297: 873-7.
    • (1977) N Engl J Med , vol.297 , pp. 873-877
    • Small, D.M.1
  • 2
    • 58549099453 scopus 로고    scopus 로고
    • Inflammation and plaque vulnerability
    • Shah PK. Inflammation and plaque vulnerability. Cardiovasc Drugs Ther 2009; 23: 31-40.
    • (2009) Cardiovasc Drugs Ther , vol.23 , pp. 31-40
    • Shah, P.K.1
  • 3
    • 77954751562 scopus 로고    scopus 로고
    • Triggering of acute myocardial infarction: Beyond the vulnerable plaque
    • Newby DE. Triggering of acute myocardial infarction: beyond the vulnerable plaque. Heart 2010; 96: 1247-51.
    • (2010) Heart , vol.96 , pp. 1247-1251
    • Newby, D.E.1
  • 4
    • 79551553025 scopus 로고    scopus 로고
    • FDG PET imaging and cardiovascular inflammation
    • Hiari N, Rudd JH. FDG PET imaging and cardiovascular inflammation. Curr Cardiol Rep 2011; 13: 43-8.
    • (2011) Curr Cardiol Rep , vol.13 , pp. 43-48
    • Hiari, N.1    Rudd, J.H.2
  • 6
    • 80054829317 scopus 로고    scopus 로고
    • Cox-2 gene polymorphism and IL-6 levels in coronary artery disease
    • Ol KK, Agachan B, Gormus U, Toptas B, Isbir T. Cox-2 gene polymorphism and IL-6 levels in coronary artery disease. Genet Mol Res 2011; 10: 810-6.
    • (2011) Genet Mol Res , vol.10 , pp. 810-816
    • Ol, K.K.1    Agachan, B.2    Gormus, U.3    Toptas, B.4    Isbir, T.5
  • 7
    • 77954242107 scopus 로고    scopus 로고
    • TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure
    • Kleinbongard P, Heusch G, Schulz R. TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure. Pharmacol Ther 2010; 127: 295-314.
    • (2010) Pharmacol Ther , vol.127 , pp. 295-314
    • Kleinbongard, P.1    Heusch, G.2    Schulz, R.3
  • 8
    • 79151473757 scopus 로고    scopus 로고
    • Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability
    • Erbel C, Dengler TJ, Wangler S, et al. Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability. Basic Res Cardiol 2011; 106: 125-34.
    • (2011) Basic Res Cardiol , vol.106 , pp. 125-134
    • Erbel, C.1    Dengler, T.J.2    Wangler, S.3
  • 9
    • 71549121695 scopus 로고    scopus 로고
    • Treating inflammation in atherosclerotic cardiovascular disease: Emerging therapies
    • Klingenberg R, Hansson GK. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur Heart J 2009; 30: 2838-44.
    • (2009) Eur Heart J , vol.30 , pp. 2838-2844
    • Klingenberg, R.1    Hansson, G.K.2
  • 10
    • 24644458574 scopus 로고    scopus 로고
    • C-reactive protein as a predictor of cardiovascular risk in a population with a high prevalence of diabetes: The Strong Heart Study
    • Best LG, Zhang Y, Lee ET, et al. C-reactive protein as a predictor of cardiovascular risk in a population with a high prevalence of diabetes: the Strong Heart Study. Circulation 2005; 112: 1289-95.
    • (2005) Circulation , vol.112 , pp. 1289-1295
    • Best, L.G.1    Zhang, Y.2    Lee, E.T.3
  • 11
    • 43549117072 scopus 로고    scopus 로고
    • Use of multiple biomarkers to improve the prediction of death from cardiovascular causes
    • Zethelius B, Berglund L, Sundstrom J, et al. Use of multiple biomarkers to improve the prediction of death from cardiovascular causes. N Engl J Med 2008; 358: 2107-16.
    • (2008) N Engl J Med , vol.358 , pp. 2107-2116
    • Zethelius, B.1    Berglund, L.2    Sundstrom, J.3
  • 12
    • 75749148425 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: Transition from theory to practice
    • Libby P, Okamoto Y, Rocha VZ, Folco E. Inflammation in atherosclerosis: transition from theory to practice. Circ J 2010; 74: 213-20.
    • (2010) Circ J , vol.74 , pp. 213-220
    • Libby, P.1    Okamoto, Y.2    Rocha, V.Z.3    Folco, E.4
  • 13
    • 0037432305 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis
    • Solomon DH, Karlson EW, Rimm EB, et al. Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation 2003; 107: 1303-7.
    • (2003) Circulation , vol.107 , pp. 1303-1307
    • Solomon, D.H.1    Karlson, E.W.2    Rimm, E.B.3
  • 14
    • 13444294254 scopus 로고    scopus 로고
    • The risk of congestive heart failure in rheumatoid arthritis: A population-based study over 46 years
    • Nicola PJ, Maradit-Kremers H, Roger VL, et al. The risk of congestive heart failure in rheumatoid arthritis: a population-based study over 46 years. Arthritis Rheum 2005; 52: 412-20.
    • (2005) Arthritis Rheum , vol.52 , pp. 412-420
    • Nicola, P.J.1    Maradit-Kremers, H.2    Roger, V.L.3
  • 15
    • 84869081020 scopus 로고    scopus 로고
    • Clinical value of drugs targeting inflammation for the management of coronary artery disease
    • Duchatelle V, Kritikou EA, Tardif JC. Clinical value of drugs targeting inflammation for the management of coronary artery disease. Can J Cardiol 2012; 28: 678-86.
    • (2012) Can J Cardiol , vol.28 , pp. 678-686
    • Duchatelle, V.1    Kritikou, E.A.2    Tardif, J.C.3
  • 17
    • 0037225374 scopus 로고    scopus 로고
    • Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis
    • Wolfe F, Freundlich B, Straus WL. Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis. J Rheumatol 2003; 30: 36-40.
    • (2003) J Rheumatol , vol.30 , pp. 36-40
    • Wolfe, F.1    Freundlich, B.2    Straus, W.L.3
  • 18
    • 0035676529 scopus 로고    scopus 로고
    • High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors
    • del Rincon ID, Williams K, Stern MP, Freeman GL, Escalante A. High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 2001; 44: 2737-45.
    • (2001) Arthritis Rheum , vol.44 , pp. 2737-2745
    • del Rincon, I.D.1    Williams, K.2    Stern, M.P.3    Freeman, G.L.4    Escalante, A.5
  • 19
    • 75749118959 scopus 로고    scopus 로고
    • EULAR evidencebased recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis
    • Peters MJ, Symmons DP, McCarey D, et al. EULAR evidencebased recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis. Ann Rheum Dis 2010; 69: 325-31.
    • (2010) Ann Rheum Dis , vol.69 , pp. 325-331
    • Peters, M.J.1    Symmons, D.P.2    McCarey, D.3
  • 21
    • 43849103005 scopus 로고    scopus 로고
    • Aggressive Reduction of Inflammation Stops Events Trial I. Effects of succinobucol (AGI-1067) after an acute coronary syndrome: A randomised, doubleblind, placebo-controlled trial
    • Tardif JC, McMurray JJ, Klug E, et al. Aggressive Reduction of Inflammation Stops Events Trial I. Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, doubleblind, placebo-controlled trial. Lancet 2008; 371: 1761-8.
    • (2008) Lancet , vol.371 , pp. 1761-1768
    • Tardif, J.C.1    McMurray, J.J.2    Klug, E.3
  • 22
    • 63649095045 scopus 로고    scopus 로고
    • Reduction in Creactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: A prospective study of the JUPITER trial
    • Ridker PM, Danielson E, Fonseca FA, et al. Reduction in Creactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 2009; 373: 1175-82.
    • (2009) Lancet , vol.373 , pp. 1175-1182
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 23
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 24
    • 84859495141 scopus 로고    scopus 로고
    • Updated consensus statement on biological agents for the treatment of rheumatic diseases 2011
    • Furst DE, Keystone EC, Braun J, et al. Updated consensus statement on biological agents for the treatment of rheumatic diseases 2011. Ann Rheum Dis 2012; 71 Suppl 2: i2-45.
    • (2012) Ann Rheum Dis , vol.71 , Issue.SUPPL. 2
    • Furst, D.E.1    Keystone, E.C.2    Braun, J.3
  • 25
    • 40649091425 scopus 로고    scopus 로고
    • Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: A multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity
    • Kerekes G, Szekanecz Z, Der H, et al. Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity. J Rheumatol 2008; 35: 398-406.
    • (2008) J Rheumatol , vol.35 , pp. 398-406
    • Kerekes, G.1    Szekanecz, Z.2    Der, H.3
  • 26
    • 0031890673 scopus 로고    scopus 로고
    • Human monocyteendothelial cell interaction induces platelet-derived growth factor expression
    • Funayama H, Ikeda U, Takahashi M, et al. Human monocyteendothelial cell interaction induces platelet-derived growth factor expression. Cardiovasc Res 1998; 37: 216-24.
    • (1998) Cardiovasc Res , vol.37 , pp. 216-224
    • Funayama, H.1    Ikeda, U.2    Takahashi, M.3
  • 27
    • 85027945907 scopus 로고    scopus 로고
    • Macrophage-derived tumor necrosis factor-alpha is an early component of the molecular cascade leading to angiogenesis in response to aortic injury
    • Ligresti G, Aplin AC, Zorzi P, Morishita A, Nicosia RF. Macrophage-derived tumor necrosis factor-alpha is an early component of the molecular cascade leading to angiogenesis in response to aortic injury. Arterioscler Thromb Vasc Biol 2011; 31: 1151-9.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1151-1159
    • Ligresti, G.1    Aplin, A.C.2    Zorzi, P.3    Morishita, A.4    Nicosia, R.F.5
  • 28
    • 77950990411 scopus 로고    scopus 로고
    • TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 phosphorylation-, and NFkappaB-dependent manner
    • Chan J, Prado-Lourenco L, Khachigian LM, Bennett MR, Di Bartolo BA, Kavurma MM. TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 phosphorylation-, and NFkappaB-dependent manner. Circ Res 2010; 106: 1061-71.
    • (2010) Circ Res , vol.106 , pp. 1061-1071
    • Chan, J.1    Prado-Lourenco, L.2    Khachigian, L.M.3    Bennett, M.R.4    Di Bartolo, B.A.5    Kavurma, M.M.6
  • 29
    • 82955203168 scopus 로고    scopus 로고
    • VEGFR2 signalling contributes to increased endothelial susceptibility to TNF-alpha under chronic non-uniform shear stress
    • Urschel K, Garlichs CD, Daniel WG, Cicha I. VEGFR2 signalling contributes to increased endothelial susceptibility to TNF-alpha under chronic non-uniform shear stress. Atherosclerosis 2011; 219: 499-509.
    • (2011) Atherosclerosis , vol.219 , pp. 499-509
    • Urschel, K.1    Garlichs, C.D.2    Daniel, W.G.3    Cicha, I.4
  • 30
    • 67651146363 scopus 로고    scopus 로고
    • Inflammatory cytokines in vascular dysfunction and vascular disease
    • Sprague AH, Khalil RA. Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol 2009; 78: 539-52.
    • (2009) Biochem Pharmacol , vol.78 , pp. 539-552
    • Sprague, A.H.1    Khalil, R.A.2
  • 32
    • 15444362300 scopus 로고    scopus 로고
    • Blockade of endogenous cytokines mitigates neointimal formation in obese Zucker rats
    • Takeda R, Suzuki E, Satonaka H, et al. Blockade of endogenous cytokines mitigates neointimal formation in obese Zucker rats. Circulation 2005; 111: 1398-406.
    • (2005) Circulation , vol.111 , pp. 1398-1406
    • Takeda, R.1    Suzuki, E.2    Satonaka, H.3
  • 33
    • 34447333111 scopus 로고    scopus 로고
    • Response to anti-tumour necrosis factor alpha blockade is associated with reduction of carotid intima-media thickness in patients with active rheumatoid arthritis
    • Del Porto F, Lagana B, Lai S, et al. Response to anti-tumour necrosis factor alpha blockade is associated with reduction of carotid intima-media thickness in patients with active rheumatoid arthritis. Rheumatology (Oxford) 2007; 46: 1111-5.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 1111-1115
    • Del Porto, F.1    Lagana, B.2    Lai, S.3
  • 34
    • 84864941948 scopus 로고    scopus 로고
    • Anti-TNF-alpha-adalimumab therapy is associated with persistent improvement of endothelial function without progression of carotid intima-media wall thickness in patients with rheumatoid arthritis refractory to conventional therapy
    • Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Miranda-Filloy JA, et al. Anti-TNF-alpha-adalimumab therapy is associated with persistent improvement of endothelial function without progression of carotid intima-media wall thickness in patients with rheumatoid arthritis refractory to conventional therapy. Mediat Inflamm 2012; 2012: 674265.
    • (2012) Mediat Inflamm , vol.2012 , pp. 674265
    • Gonzalez-Juanatey, C.1    Vazquez-Rodriguez, T.R.2    Miranda-Filloy, J.A.3
  • 35
    • 75049085546 scopus 로고    scopus 로고
    • Vascular effects of biologic agents in RA and spondyloarthropathies
    • Szekanecz Z, Kerekes G, Soltesz P. Vascular effects of biologic agents in RA and spondyloarthropathies. Nat Rev Rheumatol 2009; 5: 677-84.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 677-684
    • Szekanecz, Z.1    Kerekes, G.2    Soltesz, P.3
  • 36
    • 67651207999 scopus 로고    scopus 로고
    • Infliximab improves vascular stiffness in patients with rheumatoid arthritis
    • Wong M, Oakley SP, Young L, et al. Infliximab improves vascular stiffness in patients with rheumatoid arthritis. Ann Rheum Dis 2009; 68: 1277-84.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1277-1284
    • Wong, M.1    Oakley, S.P.2    Young, L.3
  • 37
    • 73349112920 scopus 로고    scopus 로고
    • Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritis
    • Galarraga B, Khan F, Kumar P, Pullar T, Belch JJ. Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritis. Rheumatology (Oxford) 2009; 48: 1418-23.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 1418-1423
    • Galarraga, B.1    Khan, F.2    Kumar, P.3    Pullar, T.4    Belch, J.J.5
  • 38
    • 84861182408 scopus 로고    scopus 로고
    • Effect of 1-year anti-TNF-alpha therapy on aortic stiffness, carotid atherosclerosis, and calprotectin in inflammatory arthropathies: A controlled study
    • Angel K, Provan SA, Fagerhol MK, Mowinckel P, Kvien TK, Atar D. Effect of 1-year anti-TNF-alpha therapy on aortic stiffness, carotid atherosclerosis, and calprotectin in inflammatory arthropathies: a controlled study. Am J Hypertens 2012; 25: 644-50.
    • (2012) Am J Hypertens , vol.25 , pp. 644-650
    • Angel, K.1    Provan, S.A.2    Fagerhol, M.K.3    Mowinckel, P.4    Kvien, T.K.5    Atar, D.6
  • 39
    • 33748519856 scopus 로고    scopus 로고
    • Influence of anti-TNF-alpha infliximab therapy on adhesion molecules associated with atherogenesis in patients with rheumatoid arthritis
    • Gonzalez-Gay MA, Garcia-Unzueta MT, De Matias JM, et al. Influence of anti-TNF-alpha infliximab therapy on adhesion molecules associated with atherogenesis in patients with rheumatoid arthritis. Clin Exp Rheumatol 2006; 24: 373-9.
    • (2006) Clin Exp Rheumatol , vol.24 , pp. 373-379
    • Gonzalez-Gay, M.A.1    Garcia-Unzueta, M.T.2    de Matias, J.M.3
  • 40
    • 22244443784 scopus 로고    scopus 로고
    • Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascular events in patients with rheumatoid arthritis
    • Jacobsson LT, Turesson C, Gulfe A, et al. Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascular events in patients with rheumatoid arthritis. J Rheumatol 2005; 32: 1213-8.
    • (2005) J Rheumatol , vol.32 , pp. 1213-1218
    • Jacobsson, L.T.1    Turesson, C.2    Gulfe, A.3
  • 41
    • 21244436822 scopus 로고    scopus 로고
    • Anti-rheumatic drug use and risk of hospitalization for congestive heart failure in rheumatoid arthritis
    • Bernatsky S, Hudson M, Suissa S. Anti-rheumatic drug use and risk of hospitalization for congestive heart failure in rheumatoid arthritis. Rheumatology (Oxford) 2005; 44: 677-80.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 677-680
    • Bernatsky, S.1    Hudson, M.2    Suissa, S.3
  • 42
    • 1242315583 scopus 로고    scopus 로고
    • Heart failure in rheumatoid arthritis: Rates, predictors, and the effect of anti-tumor necrosis factor therapy
    • Wolfe F, Michaud K. Heart failure in rheumatoid arthritis: rates, predictors, and the effect of anti-tumor necrosis factor therapy. Am J Med 2004; 116: 305-11.
    • (2004) Am J Med , vol.116 , pp. 305-311
    • Wolfe, F.1    Michaud, K.2
  • 43
    • 78249272692 scopus 로고    scopus 로고
    • No evidence of association between anti-tumor necrosis factor treatment and mortality in patients with rheumatoid arthritis: Results from the British Society for Rheumatology Biologics Register
    • Lunt M, Watson KD, Dixon WG, Symmons DP, Hyrich KL. No evidence of association between anti-tumor necrosis factor treatment and mortality in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Arthritis Rheum 2010; 62: 3145-53.
    • (2010) Arthritis Rheum , vol.62 , pp. 3145-3153
    • Lunt, M.1    Watson, K.D.2    Dixon, W.G.3    Symmons, D.P.4    Hyrich, K.L.5
  • 44
    • 34147126829 scopus 로고    scopus 로고
    • The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk
    • Popa C, Netea MG, van Riel PL, van der Meer JW, Stalenhoef AF. The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res 2007; 48: 751-62.
    • (2007) J Lipid Res , vol.48 , pp. 751-762
    • Popa, C.1    Netea, M.G.2    van Riel, P.L.3    van der Meer, J.W.4    Stalenhoef, A.F.5
  • 45
    • 60649121623 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-alpha blockade on metabolic syndrome components in psoriasis and psoriatic arthritis and additional lessons learned from rheumatoid arthritis
    • Channual J, Wu JJ, Dann FJ. Effects of tumor necrosis factor-alpha blockade on metabolic syndrome components in psoriasis and psoriatic arthritis and additional lessons learned from rheumatoid arthritis. Dermatol Ther 2009; 22: 61-73.
    • (2009) Dermatol Ther , vol.22 , pp. 61-73
    • Channual, J.1    Wu, J.J.2    Dann, F.J.3
  • 46
    • 84874543264 scopus 로고    scopus 로고
    • Effects of the TNF alpha Antagonist Adalimumab on Arterial Inflammation Assessed by Positron Emission Tomography in Patients with Psoriasis: Results of a Randomized Controlled Trial
    • Bissonnette R, Tardif JC, Harel F, Pressacco J, Bolduc C, Guertin MC. Effects of the TNF alpha Antagonist Adalimumab on Arterial Inflammation Assessed by Positron Emission Tomography in Patients with Psoriasis: Results of a Randomized Controlled Trial. Circ Cardiovasc Imaging 2013; 6(1): 83-90.
    • (2013) Circ Cardiovasc Imaging , vol.6 , Issue.1 , pp. 83-90
    • Bissonnette, R.1    Tardif, J.C.2    Harel, F.3    Pressacco, J.4    Bolduc, C.5    Guertin, M.C.6
  • 47
    • 18644374105 scopus 로고    scopus 로고
    • Blocking IL-1 in systemic inflammation
    • Dinarello CA. Blocking IL-1 in systemic inflammation. J Exp Med 2005; 201: 1355-9.
    • (2005) J Exp Med , vol.201 , pp. 1355-1359
    • Dinarello, C.A.1
  • 49
    • 79953813107 scopus 로고    scopus 로고
    • Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
    • Dinarello CA. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 2011; 117: 3720-32.
    • (2011) Blood , vol.117 , pp. 3720-3732
    • Dinarello, C.A.1
  • 50
    • 0037388984 scopus 로고    scopus 로고
    • Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice
    • Kirii H, Niwa T, Yamada Y, et al. Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2003; 23: 656-60.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 656-660
    • Kirii, H.1    Niwa, T.2    Yamada, Y.3
  • 51
    • 33645454887 scopus 로고    scopus 로고
    • Interleukin-1beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice
    • Chamberlain J, Evans D, King A, et al. Interleukin-1beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice. Am J Pathol 2006; 168: 1396-403.
    • (2006) Am J Pathol , vol.168 , pp. 1396-1403
    • Chamberlain, J.1    Evans, D.2    King, A.3
  • 52
    • 0038124692 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist (IL-1RN) genotype modulates the replicative capacity of human endothelial cells
    • Dewberry RM, Crossman DC, Francis SE. Interleukin-1 receptor antagonist (IL-1RN) genotype modulates the replicative capacity of human endothelial cells. Circ Res 2003; 92: 1285-7.
    • (2003) Circ Res , vol.92 , pp. 1285-1287
    • Dewberry, R.M.1    Crossman, D.C.2    Francis, S.E.3
  • 53
    • 0036023618 scopus 로고    scopus 로고
    • Interleukin-1beta inhibits expression of p21(WAF1/CIP1) and p27(KIP1) and enhances proliferation in response to plateletderived growth factor-BB in smooth muscle cells
    • Nathe TJ, Deou J, Walsh B, Bourns B, Clowes AW, Daum G. Interleukin-1beta inhibits expression of p21(WAF1/CIP1) and p27(KIP1) and enhances proliferation in response to plateletderived growth factor-BB in smooth muscle cells. Arterioscler Thromb Vasc Biol 2002; 22: 1293-8.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1293-1298
    • Nathe, T.J.1    Deou, J.2    Walsh, B.3    Bourns, B.4    Clowes, A.W.5    Daum, G.6
  • 54
    • 0043075883 scopus 로고    scopus 로고
    • Deficiency of interleukin-1 receptor antagonist promotes neointimal formation after injury
    • Isoda K, Shiigai M, Ishigami N, et al. Deficiency of interleukin-1 receptor antagonist promotes neointimal formation after injury. Circulation 2003; 108: 516-8.
    • (2003) Circulation , vol.108 , pp. 516-518
    • Isoda, K.1    Shiigai, M.2    Ishigami, N.3
  • 55
    • 77951800951 scopus 로고    scopus 로고
    • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
    • Duewell P, Kono H, Rayner KJ, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 2010; 464: 1357-61.
    • (2010) Nature , vol.464 , pp. 1357-1361
    • Duewell, P.1    Kono, H.2    Rayner, K.J.3
  • 56
    • 0028987022 scopus 로고
    • Interleukin-1 beta induces expression of adhesion molecules in human vascular smooth muscle cells and enhances adhesion of leukocytes to smooth muscle cells
    • Wang X, Feuerstein GZ, Gu JL, Lysko PG, Yue TL. Interleukin-1 beta induces expression of adhesion molecules in human vascular smooth muscle cells and enhances adhesion of leukocytes to smooth muscle cells. Atherosclerosis 1995; 115: 89-98.
    • (1995) Atherosclerosis , vol.115 , pp. 89-98
    • Wang, X.1    Feuerstein, G.Z.2    Gu, J.L.3    Lysko, P.G.4    Yue, T.L.5
  • 57
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009; 27: 519-50.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 58
    • 0033594811 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: Evidence for activation by proinflammatory mediators
    • Rajavashisth TB, Xu XP, Jovinge S, et al. Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators. Circulation 1999; 99: 3103-9.
    • (1999) Circulation , vol.99 , pp. 3103-3109
    • Rajavashisth, T.B.1    Xu, X.P.2    Jovinge, S.3
  • 59
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis--an inflammatory disease
    • Ross R. Atherosclerosis--an inflammatory disease. N Engl J Med 1999; 340: 115-26.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 60
    • 35248883867 scopus 로고    scopus 로고
    • Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism
    • Kamari Y, Werman-Venkert R, Shaish A, et al. Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis 2007; 195: 31-8.
    • (2007) Atherosclerosis , vol.195 , pp. 31-38
    • Kamari, Y.1    Werman-Venkert, R.2    Shaish, A.3
  • 61
    • 0037418208 scopus 로고    scopus 로고
    • IL-1 is required for tumor invasiveness and angiogenesis
    • Voronov E, Shouval DS, Krelin Y, et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci USA 2003; 100: 2645-50.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2645-2650
    • Voronov, E.1    Shouval, D.S.2    Krelin, Y.3
  • 62
    • 0034677174 scopus 로고    scopus 로고
    • Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene
    • Nicklin MJ, Hughes DE, Barton JL, Ure JM, Duff GW. Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. J Exp Med 2000; 191: 303-12.
    • (2000) J Exp Med , vol.191 , pp. 303-312
    • Nicklin, M.J.1    Hughes, D.E.2    Barton, J.L.3    Ure, J.M.4    Duff, G.W.5
  • 64
    • 64549109737 scopus 로고    scopus 로고
    • Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding
    • Chamberlain J, Francis S, Brookes Z, et al. Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PLoS One 2009; 4: e5073.
    • (2009) PLoS One , vol.4
    • Chamberlain, J.1    Francis, S.2    Brookes, Z.3
  • 65
    • 4644280450 scopus 로고    scopus 로고
    • Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: Pharmacotherapeutic implications
    • Chi H, Messas E, Levine RA, Graves DT, Amar S. Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications. Circulation 2004; 110: 1678-85.
    • (2004) Circulation , vol.110 , pp. 1678-1685
    • Chi, H.1    Messas, E.2    Levine, R.A.3    Graves, D.T.4    Amar, S.5
  • 66
    • 0032570269 scopus 로고    scopus 로고
    • Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice
    • Elhage R, Maret A, Pieraggi MT, Thiers JC, Arnal JF, Bayard F. Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice. Circulation 1998; 97: 242-4.
    • (1998) Circulation , vol.97 , pp. 242-244
    • Elhage, R.1    Maret, A.2    Pieraggi, M.T.3    Thiers, J.C.4    Arnal, J.F.5    Bayard, F.6
  • 67
    • 19444370696 scopus 로고    scopus 로고
    • Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout mice
    • Merhi-Soussi F, Kwak BR, Magne D, et al. Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout mice. Cardiovasc Res 2005; 66: 583-93.
    • (2005) Cardiovasc Res , vol.66 , pp. 583-593
    • Merhi-Soussi, F.1    Kwak, B.R.2    Magne, D.3
  • 68
    • 0033596657 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease
    • Francis SE, Camp NJ, Dewberry RM, et al. Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease. Circulation 1999; 99: 861-6.
    • (1999) Circulation , vol.99 , pp. 861-866
    • Francis, S.E.1    Camp, N.J.2    Dewberry, R.M.3
  • 69
    • 0033666905 scopus 로고    scopus 로고
    • Protective role against restenosis from an interleukin-1 receptor antagonist gene polymorphism in patients treated with coronary stenting
    • Kastrati A, Koch W, Berger PB, et al. Protective role against restenosis from an interleukin-1 receptor antagonist gene polymorphism in patients treated with coronary stenting. J Am Coll Cardiol 2000; 36: 2168-73.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2168-2173
    • Kastrati, A.1    Koch, W.2    Berger, P.B.3
  • 70
    • 78651389288 scopus 로고    scopus 로고
    • XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1betamediated diseases
    • Owyang AM, Issafras H, Corbin J, et al. XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1betamediated diseases. MAbs 2011; 3: 49-60.
    • (2011) MAbs , vol.3 , pp. 49-60
    • Owyang, A.M.1    Issafras, H.2    Corbin, J.3
  • 71
    • 77954224428 scopus 로고    scopus 로고
    • Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity
    • Roell MK, Issafras H, Bauer RJ, et al. Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity. J Biol Chem 2010; 285: 20607-14.
    • (2010) J Biol Chem , vol.285 , pp. 20607-20614
    • Roell, M.K.1    Issafras, H.2    Bauer, R.J.3
  • 72
    • 79955649518 scopus 로고    scopus 로고
    • Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein Edeficient mice
    • Bhaskar V, Yin J, Mirza AM, et al. Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein Edeficient mice. Atherosclerosis 2011; 216: 313-20.
    • (2011) Atherosclerosis , vol.216 , pp. 313-320
    • Bhaskar, V.1    Yin, J.2    Mirza, A.M.3
  • 73
    • 0034681920 scopus 로고    scopus 로고
    • Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
    • Ridker PM, Rifai N, Stampfer MJ, Hennekens CH. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 2000; 101: 1767-72.
    • (2000) Circulation , vol.101 , pp. 1767-1772
    • Ridker, P.M.1    Rifai, N.2    Stampfer, M.J.3    Hennekens, C.H.4
  • 74
    • 43249118045 scopus 로고    scopus 로고
    • Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic review
    • Danesh J, Kaptoge S, Mann AG, et al. Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review. PLoS Med 2008; 5: e78.
    • (2008) PLoS Med , vol.5
    • Danesh, J.1    Kaptoge, S.2    Mann, A.G.3
  • 75
    • 84859215358 scopus 로고    scopus 로고
    • The interleukin-6 receptor as a target for prevention of coronary heart disease: A mendelian randomisation analysis
    • Hingorani AD, Casas JP. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012; 379: 1214-24.
    • (2012) Lancet , vol.379 , pp. 1214-1224
    • Hingorani, A.D.1    Casas, J.P.2
  • 76
    • 2942720515 scopus 로고    scopus 로고
    • Beneficial cardiovascular pleiotropic effects of statins
    • Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation 2004; 109: III39-43.
    • (2004) Circulation , vol.109
    • Davignon, J.1
  • 78
    • 0031861944 scopus 로고    scopus 로고
    • Analysis of the cytokine network among tumor necrosis factor alpha, interleukin-1beta, interleukin-8, and interleukin-1 receptor antagonist in monosodium urate crystalinduced rabbit arthritis
    • Matsukawa A, Yoshimura T, Maeda T, Takahashi T, Ohkawara S, Yoshinaga M. Analysis of the cytokine network among tumor necrosis factor alpha, interleukin-1beta, interleukin-8, and interleukin-1 receptor antagonist in monosodium urate crystalinduced rabbit arthritis. Lab Invest 1998; 78: 559-69.
    • (1998) Lab Invest , vol.78 , pp. 559-569
    • Matsukawa, A.1    Yoshimura, T.2    Maeda, T.3    Takahashi, T.4    Ohkawara, S.5    Yoshinaga, M.6
  • 79
    • 0020428342 scopus 로고
    • Cytoplasmic microtubules in polymorphonuclear leukocytes: Effects of chemotactic stimulation and colchicine
    • Anderson DC, Wible LJ, Hughes BJ, Smith CW, Brinkley BR. Cytoplasmic microtubules in polymorphonuclear leukocytes: effects of chemotactic stimulation and colchicine. Cell 1982; 31: 719-29.
    • (1982) Cell , vol.31 , pp. 719-729
    • Anderson, D.C.1    Wible, L.J.2    Hughes, B.J.3    Smith, C.W.4    Brinkley, B.R.5
  • 80
    • 0017658902 scopus 로고
    • Structural analysis of human neutrophil migration. Centriole, microtubule, and microfilament orientation and function during chemotaxis
    • Malech HL, Root RK, Gallin JI. Structural analysis of human neutrophil migration. Centriole, microtubule, and microfilament orientation and function during chemotaxis. J Cell Biol 1977; 75: 666-93.
    • (1977) J Cell Biol , vol.75 , pp. 666-693
    • Malech, H.L.1    Root, R.K.2    Gallin, J.I.3
  • 81
    • 0029144844 scopus 로고
    • Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils
    • Cronstein BN, Molad Y, Reibman J, Balakhane E, Levin RI, Weissmann G. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. J Clin Invest 1995; 96: 994-1002.
    • (1995) J Clin Invest , vol.96 , pp. 994-1002
    • Cronstein, B.N.1    Molad, Y.2    Reibman, J.3    Balakhane, E.4    Levin, R.I.5    Weissmann, G.6
  • 82
    • 0037016059 scopus 로고    scopus 로고
    • Neutrophil infiltration of culprit lesions in acute coronary syndromes
    • Naruko T, Ueda M, Haze K, et al. Neutrophil infiltration of culprit lesions in acute coronary syndromes. Circulation 2002; 106: 2894-900.
    • (2002) Circulation , vol.106 , pp. 2894-2900
    • Naruko, T.1    Ueda, M.2    Haze, K.3
  • 83
    • 33644852021 scopus 로고    scopus 로고
    • Mechanism of the antiinflammatory effect of colchicine in rheumatic diseases: A possible new outlook through microarray analysis
    • Ben-Chetrit E, Bergmann S, Sood R. Mechanism of the antiinflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysis. Rheumatology (Oxford) 2006; 45: 274-82.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 274-282
    • Ben-Chetrit, E.1    Bergmann, S.2    Sood, R.3
  • 84
    • 35348923754 scopus 로고    scopus 로고
    • The role of interleukin-1 and the inflammasome in gout: Implications for therapy
    • Pope RM, Tschopp J. The role of interleukin-1 and the inflammasome in gout: implications for therapy. Arthritis Rheum 2007; 56: 3183-8.
    • (2007) Arthritis Rheum , vol.56 , pp. 3183-3188
    • Pope, R.M.1    Tschopp, J.2
  • 85
    • 84858630049 scopus 로고    scopus 로고
    • A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?
    • Wen H, Ting JP, O'Neill LA. A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation? Nat Immunol 2012; 13: 352-7.
    • (2012) Nat Immunol , vol.13 , pp. 352-357
    • Wen, H.1    Ting, J.P.2    O'Neill, L.A.3
  • 86
    • 0026681698 scopus 로고
    • Colchicine prevents tumor necrosis factor-induced toxicity in vivo
    • Tiegs G, Freudenberg MA, Galanos C, Wendel A. Colchicine prevents tumor necrosis factor-induced toxicity in vivo. Infect Immun 1992; 60: 1941-5.
    • (1992) Infect Immun , vol.60 , pp. 1941-1945
    • Tiegs, G.1    Freudenberg, M.A.2    Galanos, C.3    Wendel, A.4
  • 87
    • 0031253739 scopus 로고    scopus 로고
    • Colchicine down-regulates lipopolysaccharide-induced granulocytemacrophage colony-stimulating factor production in murine macrophages
    • Rao P, Falk LA, Dougherty SF, Sawada T, Pluznik DH. Colchicine down-regulates lipopolysaccharide-induced granulocytemacrophage colony-stimulating factor production in murine macrophages. J Immunol 1997; 159: 3531-9.
    • (1997) J Immunol , vol.159 , pp. 3531-3539
    • Rao, P.1    Falk, L.A.2    Dougherty, S.F.3    Sawada, T.4    Pluznik, D.H.5
  • 88
    • 0028275646 scopus 로고
    • Crystal-induced neutrophil activation. V. Differential production of biologically active IL-1 and IL-1 receptor antagonist
    • Roberge CJ, de Medicis R, Dayer JM, et al. Crystal-induced neutrophil activation. V. Differential production of biologically active IL-1 and IL-1 receptor antagonist. J Immunol 1994; 152: 5485-94.
    • (1994) J Immunol , vol.152 , pp. 5485-5494
    • Roberge, C.J.1    de Medicis, R.2    Dayer, J.M.3
  • 89
    • 0027491538 scopus 로고
    • Disruption of microtubule network in human monocytes induces expression of interleukin-1 but not that of interleukin-6 nor tumor necrosis factor-alpha. Involvement of protein kinase A stimulation
    • Manie S, Schmid-Alliana A, Kubar J, Ferrua B, Rossi B. Disruption of microtubule network in human monocytes induces expression of interleukin-1 but not that of interleukin-6 nor tumor necrosis factor-alpha. Involvement of protein kinase A stimulation. J Biol Chem 1993; 268: 13675-81.
    • (1993) J Biol Chem , vol.268 , pp. 13675-13681
    • Manie, S.1    Schmid-Alliana, A.2    Kubar, J.3    Ferrua, B.4    Rossi, B.5
  • 90
    • 2942638213 scopus 로고    scopus 로고
    • In vitro expression of matrix metalloproteinase-1, tissue inhibitor of metalloproteinase-1 and transforming growth factor-beta1 in human periodontal ligament fibroblasts
    • Nahm DS, Kim HJ, Mah J, Baek SH. In vitro expression of matrix metalloproteinase-1, tissue inhibitor of metalloproteinase-1 and transforming growth factor-beta1 in human periodontal ligament fibroblasts. Eur J Orthod 2004; 26: 129-35.
    • (2004) Eur J Orthod , vol.26 , pp. 129-135
    • Nahm, D.S.1    Kim, H.J.2    Mah, J.3    Baek, S.H.4
  • 91
    • 0031894321 scopus 로고    scopus 로고
    • Extracellular matrix modulates macrophage functions characteristic to atheroma: Collagen type I enhances acquisition of resident macrophage traits by human peripheral blood monocytes in vitro
    • Wesley RB, 2nd, Meng X, Godin D, Galis ZS. Extracellular matrix modulates macrophage functions characteristic to atheroma: collagen type I enhances acquisition of resident macrophage traits by human peripheral blood monocytes in vitro. Arterioscler Thromb Vasc Biol 1998; 18: 432-40.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 432-440
    • Wesley II, R.B.1    Meng, X.2    Godin, D.3    Galis, Z.S.4
  • 92
    • 84858865440 scopus 로고    scopus 로고
    • Effect of colchicine compared with placebo on high sensitivity Creactive protein in patients with acute coronary syndrome or acute stroke: A pilot randomized controlled trial
    • Raju NC, Yi Q, Nidorf M, Fagel ND, Hiralal R, Eikelboom JW. Effect of colchicine compared with placebo on high sensitivity Creactive protein in patients with acute coronary syndrome or acute stroke: a pilot randomized controlled trial. J Thromb Thrombolysis 2012; 33: 88-94.
    • (2012) J Thromb Thrombolysis , vol.33 , pp. 88-94
    • Raju, N.C.1    Yi, Q.2    Nidorf, M.3    Fagel, N.D.4    Hiralal, R.5    Eikelboom, J.W.6
  • 93
    • 84884270522 scopus 로고    scopus 로고
    • Low dose colchicine for secondary prevention of cardiovascular disease (The LoDoCo trial). Special science session
    • [Epub ahead of print]
    • Nidorf M. Low dose colchicine for secondary prevention of cardiovascular disease (The LoDoCo trial). Special science session. AHA 2012 [Epub ahead of print].
    • (2012) AHA
    • Nidorf, M.1
  • 94
    • 0023263647 scopus 로고
    • Prostaglandins and leukotrienes as inflammatory mediators
    • Salmon JA, Higgs GA. Prostaglandins and leukotrienes as inflammatory mediators. Br Med Bull 1987; 43: 285-96.
    • (1987) Br Med Bull , vol.43 , pp. 285-296
    • Salmon, J.A.1    Higgs, G.A.2
  • 95
    • 0020416021 scopus 로고
    • Synthesis and metabolism of leukotriene B4 in human neutrophils measured by specific radioimmunoassay
    • Salmon JA, Simmons PM, Palmer RM. Synthesis and metabolism of leukotriene B4 in human neutrophils measured by specific radioimmunoassay. FEBS Lett 1982; 146: 18-22.
    • (1982) FEBS Lett , vol.146 , pp. 18-22
    • Salmon, J.A.1    Simmons, P.M.2    Palmer, R.M.3
  • 96
    • 0020075001 scopus 로고
    • Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages
    • Humes JL, Sadowski S, Galavage M, et al. Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages. J Biol Chem 1982; 257: 1591-4.
    • (1982) J Biol Chem , vol.257 , pp. 1591-1594
    • Humes, J.L.1    Sadowski, S.2    Galavage, M.3
  • 97
    • 0346787907 scopus 로고    scopus 로고
    • From asthma to atherosclerosis--5-lipoxygenase, leukotrienes, and inflammation
    • De Caterina R, Zampolli A. From asthma to atherosclerosis--5-lipoxygenase, leukotrienes, and inflammation. N Engl J Med 2004; 350: 4-7.
    • (2004) N Engl J Med , vol.350 , pp. 4-7
    • de Caterina, R.1    Zampolli, A.2
  • 98
    • 73449139739 scopus 로고    scopus 로고
    • Participation of 5-lipoxygenasederived LTB(4) in 4-hydroxynonenal-enhanced MMP-2 production in vascular smooth muscle cells
    • Seo KW, Lee SJ, Kim CE, et al. Participation of 5-lipoxygenasederived LTB(4) in 4-hydroxynonenal-enhanced MMP-2 production in vascular smooth muscle cells. Atherosclerosis 2010; 208: 56-61.
    • (2010) Atherosclerosis , vol.208 , pp. 56-61
    • Seo, K.W.1    Lee, S.J.2    Kim, C.E.3
  • 99
    • 0032560647 scopus 로고    scopus 로고
    • Differential leukotriene constrictor responses in human atherosclerotic coronary arteries
    • Allen S, Dashwood M, Morrison K, Yacoub M. Differential leukotriene constrictor responses in human atherosclerotic coronary arteries. Circulation 1998; 97: 2406-13.
    • (1998) Circulation , vol.97 , pp. 2406-2413
    • Allen, S.1    Dashwood, M.2    Morrison, K.3    Yacoub, M.4
  • 100
    • 0037417973 scopus 로고    scopus 로고
    • Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis
    • Spanbroek R, Grabner R, Lotzer K, et al. Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis. Proc Natl Acad Sci USA 2003; 100: 1238-43.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1238-1243
    • Spanbroek, R.1    Grabner, R.2    Lotzer, K.3
  • 101
    • 23244445221 scopus 로고    scopus 로고
    • Association between 5-lipoxygenase expression and plaque instability in humans
    • Cipollone F, Mezzetti A, Fazia ML, et al. Association between 5-lipoxygenase expression and plaque instability in humans. Arterioscler Thromb Vasc Biol 2005; 25: 1665-70.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1665-1670
    • Cipollone, F.1    Mezzetti, A.2    Fazia, M.L.3
  • 102
    • 0032411512 scopus 로고    scopus 로고
    • Pharmacokinetics of a novel 5-lipoxygenase inhibitor (ABT-761) in pediatric patients with asthma
    • Wong SL, Kearns GL, Kemp JP, et al. Pharmacokinetics of a novel 5-lipoxygenase inhibitor (ABT-761) in pediatric patients with asthma. Eur J Clin Pharmacol 1998; 54: 715-9.
    • (1998) Eur J Clin Pharmacol , vol.54 , pp. 715-719
    • Wong, S.L.1    Kearns, G.L.2    Kemp, J.P.3
  • 103
    • 0031925949 scopus 로고    scopus 로고
    • Effects of a 5-lipoxygenase inhibitor, ABT-761, on exerciseinduced bronchoconstriction and urinary LTE4 in asthmatic patients
    • Lehnigk B, Rabe KF, Dent G, Herst RS, Carpentier PJ, Magnussen H. Effects of a 5-lipoxygenase inhibitor, ABT-761, on exerciseinduced bronchoconstriction and urinary LTE4 in asthmatic patients. Eur Respir J 1998; 11: 617-23.
    • (1998) Eur Respir J , vol.11 , pp. 617-623
    • Lehnigk, B.1    Rabe, K.F.2    Dent, G.3    Herst, R.S.4    Carpentier, P.J.5    Magnussen, H.6
  • 104
    • 77953642757 scopus 로고    scopus 로고
    • Treatment with 5-lipoxygenase inhibitor VIA-2291 (Atreleuton) in patients with recent acute coronary syndrome
    • Tardif JC, L'Allier P. L, Ibrahim R, et al. Treatment with 5-lipoxygenase inhibitor VIA-2291 (Atreleuton) in patients with recent acute coronary syndrome. Circ Cardiovasc Imaging 2010; 3: 298-307.
    • (2010) Circ Cardiovasc Imaging , vol.3 , pp. 298-307
    • Tardif, J.C.1    L'Allier, P.L.2    Ibrahim, R.3
  • 105
    • 75649117820 scopus 로고    scopus 로고
    • The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics
    • Lucas A, Liu L, Dai E, et al. The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics. Adv Exp Med Biol 2009; 666: 132-56.
    • (2009) Adv Exp Med Biol , vol.666 , pp. 132-156
    • Lucas, A.1    Liu, L.2    Dai, E.3
  • 106
    • 32944461502 scopus 로고    scopus 로고
    • Serpins, the vasculature, and viral therapeutics
    • Richardson J, Viswanathan K, Lucas A. Serpins, the vasculature, and viral therapeutics. Front Biosci 2006; 11: 1042-56.
    • (2006) Front Biosci , vol.11 , pp. 1042-1056
    • Richardson, J.1    Viswanathan, K.2    Lucas, A.3
  • 107
    • 34447281264 scopus 로고    scopus 로고
    • Viral serpin, Serp-1, inhibits endogenous angiogenesis in the chicken chorioallantoic membrane model
    • Richardson M, Liu L, Dunphy L, et al. Viral serpin, Serp-1, inhibits endogenous angiogenesis in the chicken chorioallantoic membrane model. Cardiovasc Pathol 2007; 16: 191-202.
    • (2007) Cardiovasc Pathol , vol.16 , pp. 191-202
    • Richardson, M.1    Liu, L.2    Dunphy, L.3
  • 108
    • 0035823595 scopus 로고    scopus 로고
    • The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
    • Silverman GA, Bird PI, Carrell RW, et al. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 2001; 276: 33293-6.
    • (2001) J Biol Chem , vol.276 , pp. 33293-33296
    • Silverman, G.A.1    Bird, P.I.2    Carrell, R.W.3
  • 109
    • 84866867001 scopus 로고    scopus 로고
    • Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro
    • Viswanathan K, Bot I, Liu L, et al. Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro. PLoS One 2012; 7: e44694.
    • (2012) PLoS One , vol.7
    • Viswanathan, K.1    Bot, I.2    Liu, L.3
  • 110
    • 0032516843 scopus 로고    scopus 로고
    • Inhibitory specificity of the anti-inflammatory myxoma virus serpin, SERP-1
    • Nash P, Whitty A, Handwerker J, Macen J, McFadden G. Inhibitory specificity of the anti-inflammatory myxoma virus serpin, SERP-1. J Biol Chem 1998; 273: 20982-91.
    • (1998) J Biol Chem , vol.273 , pp. 20982-20991
    • Nash, P.1    Whitty, A.2    Handwerker, J.3    Macen, J.4    McFadden, G.5
  • 111
    • 33646373439 scopus 로고    scopus 로고
    • Identification of myxomaviral serpin reactive site loop sequences that regulate innate immune responses
    • Dai E, Viswanathan K, Sun YM, et al. Identification of myxomaviral serpin reactive site loop sequences that regulate innate immune responses. J Biol Chem 2006; 281: 8041-50.
    • (2006) J Biol Chem , vol.281 , pp. 8041-8050
    • Dai, E.1    Viswanathan, K.2    Sun, Y.M.3
  • 112
    • 61449133139 scopus 로고    scopus 로고
    • Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B
    • Viswanathan K, Richardson J, Togonu-Bickersteth B, et al. Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B. J Leukoc Biol 2009; 85: 418-26.
    • (2009) J Leukoc Biol , vol.85 , pp. 418-426
    • Viswanathan, K.1    Richardson, J.2    Togonu-Bickersteth, B.3
  • 113
    • 0042416599 scopus 로고    scopus 로고
    • Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice
    • Bot I, von der Thusen JH, Donners MM, et al. Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice. Circ Res 2003; 93: 464-71.
    • (2003) Circ Res , vol.93 , pp. 464-471
    • Bot, I.1    von der Thusen, J.H.2    Donners, M.M.3
  • 114
    • 79953271055 scopus 로고    scopus 로고
    • Viral-derived Serp-1 as an adjunctive therapy for percutaneous coronary intervention: Another not ready for prime time player?
    • Leopold JA. Viral-derived Serp-1 as an adjunctive therapy for percutaneous coronary intervention: another not ready for prime time player? Circ Cardiovasc Interv 2010; 3: 528-30.
    • (2010) Circ Cardiovasc Interv , vol.3 , pp. 528-530
    • Leopold, J.A.1
  • 115
    • 79953287029 scopus 로고    scopus 로고
    • A randomized controlled, phase 2 trial of the viral serpin Serp-1 in patients with acute coronary syndromes undergoing percutaneous coronary intervention
    • Tardif JC, L'Allier PL, Gregoire J, et al. A randomized controlled, phase 2 trial of the viral serpin Serp-1 in patients with acute coronary syndromes undergoing percutaneous coronary intervention. Circ Cardiovasc Interv 2010; 3: 543-8.
    • (2010) Circ Cardiovasc Interv , vol.3 , pp. 543-548
    • Tardif, J.C.1    L'Allier, P.L.2    Gregoire, J.3
  • 116
    • 84961048900 scopus 로고
    • Changes in the endothelium of the aorta and the behaviour of macrophages in experimental atheroma of rabbits
    • Poole JC, Florey HW. Changes in the endothelium of the aorta and the behaviour of macrophages in experimental atheroma of rabbits. J Pathol Bacteriol 1958; 75: 245-51.
    • (1958) J Pathol Bacteriol , vol.75 , pp. 245-251
    • Poole, J.C.1    Florey, H.W.2
  • 117
    • 2442519018 scopus 로고    scopus 로고
    • Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation
    • Ley K, Kansas GS. Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nat Rev Immunol 2004; 4: 325-35.
    • (2004) Nat Rev Immunol , vol.4 , pp. 325-335
    • Ley, K.1    Kansas, G.S.2
  • 118
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • Ley K, Laudanna C, Cybulsky MI, Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 2007; 7: 678-89.
    • (2007) Nat Rev Immunol , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 119
    • 80855148802 scopus 로고    scopus 로고
    • Intravital microscopy on atherosclerosis in apolipoprotein e-deficient mice establishes microvessels as major entry pathways for leukocytes to advanced lesions
    • Eriksson EE. Intravital microscopy on atherosclerosis in apolipoprotein e-deficient mice establishes microvessels as major entry pathways for leukocytes to advanced lesions. Circulation 2011; 124: 2129-38.
    • (2011) Circulation , vol.124 , pp. 2129-2138
    • Eriksson, E.E.1
  • 120
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 121
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002; 105: 1135-43.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 122
    • 51649118633 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice
    • An G, Wang H, Tang R, et al. P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice. Circulation 2008; 117: 3227-37.
    • (2008) Circulation , vol.117 , pp. 3227-3237
    • An, G.1    Wang, H.2    Tang, R.3
  • 123
    • 0037630017 scopus 로고    scopus 로고
    • Single injection of P-selectin or P-selectin glycoprotein ligand-1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein Edeficient mice
    • Phillips JW, Barringhaus KG, Sanders JM, et al. Single injection of P-selectin or P-selectin glycoprotein ligand-1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein Edeficient mice. Circulation 2003; 107: 2244-9.
    • (2003) Circulation , vol.107 , pp. 2244-2249
    • Phillips, J.W.1    Barringhaus, K.G.2    Sanders, J.M.3
  • 124
    • 84155163983 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand-1 deficiency leads to cytokine resistance and protection against atherosclerosis in apolipoprotein E deficient mice
    • Luo W, Wang H, Ohman MK, et al. P-selectin glycoprotein ligand-1 deficiency leads to cytokine resistance and protection against atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis 2012; 220: 110-7.
    • (2012) Atherosclerosis , vol.220 , pp. 110-117
    • Luo, W.1    Wang, H.2    Ohman, M.K.3
  • 125
    • 5344250959 scopus 로고    scopus 로고
    • Alpha(1, 3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/-mice
    • Homeister JW, Daugherty A, Lowe JB. Alpha(1, 3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/-mice. Arterioscler Thromb Vasc Biol 2004; 24: 1897-903.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1897-1903
    • Homeister, J.W.1    Daugherty, A.2    Lowe, J.B.3
  • 126
    • 67650303106 scopus 로고    scopus 로고
    • Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice
    • Wang H, Zhang W, Tang R, et al. Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2009; 29: 1053-9.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1053-1059
    • Wang, H.1    Zhang, W.2    Tang, R.3
  • 127
    • 77955877752 scopus 로고    scopus 로고
    • Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carbox ylic acid (PSI-421), a Pselectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury
    • Huang A, Moretto A, Janz K, et al. Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carbox ylic acid (PSI-421), a Pselectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury. J Med Chem 2010; 53: 6003-17.
    • (2010) J Med Chem , vol.53 , pp. 6003-6017
    • Huang, A.1    Moretto, A.2    Janz, K.3
  • 128
    • 70449399276 scopus 로고    scopus 로고
    • P-selectin antagonism reduces thrombus formation in humans
    • Chelliah R, Lucking AJ, Tattersall L, et al. P-selectin antagonism reduces thrombus formation in humans. J Thromb Haemost 2009; 7: 1915-9.
    • (2009) J Thromb Haemost , vol.7 , pp. 1915-1919
    • Chelliah, R.1    Lucking, A.J.2    Tattersall, L.3


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