TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 Phosphorylation-, and NFκB-Dependent Manner

Circulation Research

Volumn 106, Issue 6, 2010, Pages 1061-1071

  Chan, Jeffrey ^a   Prado Lourenco, Leonel ^a   Khachigian, Levon M ^a   Bennett, Martin R ^a,b   Di Bartolo, Belinda A ^a   Kavurma, Mary M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Injury; TRAIL; Transcriptional regulation; VSMC proliferation

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR SP1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTICLE; BINDING SITE; BLOOD VESSEL INJURY; CELL PROLIFERATION; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL PROLIFERATION; CELLS, CULTURED; FEMORAL ARTERY; FIBROBLAST GROWTH FACTOR 2; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; MUTATION; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RATS; RECOMBINANT PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUNICA INTIMA;

EID: 77950990411     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.206029     Document Type: Article

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