LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25

Experimental and Molecular Medicine

Volumn 45, Issue 8, 2013, Pages

  Yun, Hye Jin ^a   Park, Joohyun ^b   Ho, Dong Hwan ^c   Kim, Heyjung ^c   Kim, Cy Hyun ^a   Oh, Hakjin ^c,d   Ga, Inhwa ^c   Seo, Hyemyung ^d   Chang, Sunghoe ^b   Son, Ilhong ^c   Seol, Wongi ^a,c  

^a Inje University   (South Korea)

^b Seoul National University   (South Korea)

^c Wonkwang University   (South Korea)

^d Hanyang University   (South Korea)

Author keywords

Kinase; LRRK2; SNAP 25; Snapin; SNARE vesicle; Synaptotagmin

Indexed keywords

BINDING PROTEIN; GLUTATHIONE TRANSFERASE; LEUCINE RICH REPEAT KINASE 2; RAS PROTEIN; SNAPIN PROTEIN; SNARE PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN; THREONINE; UNCLASSIFIED DRUG; LRRK2 PROTEIN, MOUSE; MUTANT PROTEIN; PHOSPHOTHREONINE; PROTEIN SERINE THREONINE KINASE; SNAPIN PROTEIN, HUMAN; SYNAPTOBREVIN 2; SYNTAXIN; VESICULAR TRANSPORT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN TISSUE; CELL COUNT; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME REGULATION; ENZYME STRUCTURE; EXOCYTOSIS; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; MUTATIONAL ANALYSIS; NERVE FIBER GROWTH; NEUROTRANSMITTER RELEASE; NONHUMAN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; SYNAPSE VESICLE; AMINO ACID SEQUENCE; ANIMAL; CELL STRAIN HEK293; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SPRAGUE DAWLEY RAT;

RATTUS;

AMINO ACID SEQUENCE; ANIMALS; EXOCYTOSIS; FEMALE; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PHOSPHORYLATION; PHOSPHOTHREONINE; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; QA-SNARE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; SYNAPTOTAGMINS; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2; VESICULAR TRANSPORT PROTEINS;

EID: 84883034462     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.68     Document Type: Article

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