-
1
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
DOI 10.1038/nature05236, PII NATURE05236
-
Bao, S., Wu, Q., McLendon, R.E., et al. (2006). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760 (Pubitemid 44949604)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
2
-
-
0034708504
-
Expression and functional analysis of Apaf-1 isoforms. Extra WD-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9
-
DOI 10.1074/jbc.275.12.8461
-
Benedict, M.A., Hu, Y., Inohara, N., et al. (2000). Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9. J Biol Chem 275, 8461-8468 (Pubitemid 30180191)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.12
, pp. 8461-8468
-
-
Benedict, M.A.1
Hu, Y.2
Inohara, N.3
Nunez, G.4
-
3
-
-
77956908962
-
Regulation of the Apaf-1- caspase-9 apoptosome
-
Bratton, S.B., and Salvesen, G.S. (2010). Regulation of the Apaf-1- caspase-9 apoptosome. J Cell Sci 123, 3209-3214
-
(2010)
J Cell Sci
, vol.123
, pp. 3209-3214
-
-
Bratton, S.B.1
Salvesen, G.S.2
-
4
-
-
0014240427
-
Amiloride A potassiumsparing natriuretic agent
-
Bull, M.B., and Laragh, J.H. (1968). Amiloride. A potassiumsparing natriuretic agent. Circulation 37, 45-53
-
(1968)
Circulation
, vol.37
, pp. 45-53
-
-
Bull, M.B.1
Laragh, J.H.2
-
5
-
-
70449567146
-
Ionizing radiation induces apoptotic signal through protein kinase Cdelta (delta) and survival signal through Akt and cyclicnucleotide response element-binding protein (CREB) in Jurkat T cells
-
Cataldi, A., Di Giacomo, V., Rapino, M., et al. (2009). Ionizing radiation induces apoptotic signal through protein kinase Cdelta (delta) and survival signal through Akt and cyclicnucleotide response element-binding protein (CREB) in Jurkat T cells. Biol Bull 217, 202-212
-
(2009)
Biol Bull
, vol.217
, pp. 202-212
-
-
Cataldi, A.1
Di Giacomo, V.2
Rapino, M.3
-
6
-
-
79958294217
-
Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells
-
Chang, J.G., Yang, D.M., Chang, W.H., et al. (2011a). Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells. PLoS One 6, e18643
-
(2011)
PLoS One
, vol.6
-
-
Chang, J.G.1
Yang, D.M.2
Chang, W.H.3
-
7
-
-
78751562185
-
Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib
-
Chang, W.H., Liu, T.C., Yang, W.K., et al. (2011b). Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib. Cancer Res 71, 383-392
-
(2011)
Cancer Res
, vol.71
, pp. 383-392
-
-
Chang, W.H.1
Liu, T.C.2
Yang, W.K.3
-
8
-
-
84863066448
-
Targeting protective autophagy exacerbates UV-triggered apoptotic cell death
-
Chen, L.H., Chu, P.M., Lee, Y.J., et al. (2012). Targeting protective autophagy exacerbates UV-triggered apoptotic cell death. Int J Mol Sci 13, 1209-1224
-
(2012)
Int J Mol Sci
, vol.13
, pp. 1209-1224
-
-
Chen, L.H.1
Chu, P.M.2
Lee, Y.J.3
-
9
-
-
70349441081
-
Fern plantderived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299
-
Chiu, C.C., Chang, H.W., Chuang, D.W., et al. (2009). Fern plantderived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299. DNA Cell Biol 28, 501-506
-
(2009)
DNA Cell Biol
, vol.28
, pp. 501-506
-
-
Chiu, C.C.1
Chang, H.W.2
Chuang, D.W.3
-
10
-
-
0842308784
-
Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells
-
DOI 10.1038/sj.bjc.6601427
-
Dunne, A.L., Price, M.E., Mothersill, C., et al. (2003). Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells. Br J Cancer 89, 2277-2283 (Pubitemid 38168011)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.12
, pp. 2277-2283
-
-
Dunne, A.L.1
Price, M.E.2
Mothersill, C.3
McKeown, S.R.4
Robson, T.5
Hirst, D.G.6
-
11
-
-
81055124259
-
Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr
-
Fedrigo, C.A., Grivicich, I., Schunemann, D.P., et al. (2011). Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr. Radiat Oncol 6, 156
-
(2011)
Radiat Oncol
, vol.6
, pp. 156
-
-
Fedrigo, C.A.1
Grivicich, I.2
Schunemann, D.P.3
-
12
-
-
79958700761
-
Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells
-
Filippi-Chiela, E.C., Villodre, E.S., Zamin, L.L., et al. (2011). Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells. PLoS One 6, e20849
-
(2011)
PLoS One
, vol.6
-
-
Filippi-Chiela, E.C.1
Villodre, E.S.2
Zamin, L.L.3
-
13
-
-
84870421733
-
TCRP1 promotes radioresistance of oral squamous cell carcinoma cells via Akt signal pathway
-
Gu, Y., Fan, S., Liu, B., et al. (2011). TCRP1 promotes radioresistance of oral squamous cell carcinoma cells via Akt signal pathway. Mol Cell Biochem 357, 107-113
-
(2011)
Mol Cell Biochem
, vol.357
, pp. 107-113
-
-
Gu, Y.1
Fan, S.2
Liu, B.3
-
14
-
-
81155126061
-
Lactate: A metabolic key player in cancer
-
Hirschhaeuser, F., Sattler, U.G., and Mueller-Klieser, W. (2011). Lactate: A metabolic key player in cancer. Cancer Res 71, 6921- 6925
-
(2011)
Cancer Res
, vol.71
, pp. 6921-6925
-
-
Hirschhaeuser, F.1
Sattler, U.G.2
Mueller-Klieser, W.3
-
15
-
-
80052829850
-
The phosphoinositide 3-kinase signaling pathway as a therapeutic target in grade IV brain tumors
-
Holand, K., Salm, F., and Arcaro, A. (2011). The phosphoinositide 3-kinase signaling pathway as a therapeutic target in grade IV brain tumors. Curr Cancer Drug Targets 11, 894-918
-
(2011)
Curr Cancer Drug Targets
, vol.11
, pp. 894-918
-
-
Holand, K.1
Salm, F.2
Arcaro, A.3
-
16
-
-
33746842309
-
DNA damage-dependent cell cycle checkpoints and genomic stability
-
DOI 10.1089/dna.2006.25.406
-
Ishikawa, K., Ishii, H., and Saito, T. (2006). DNA damagedependent cell cycle checkpoints and genomic stability. DNA Cell Biol 25, 406-411 (Pubitemid 44175332)
-
(2006)
DNA and Cell Biology
, vol.25
, Issue.7
, pp. 406-411
-
-
Ishikawa, K.1
Ishii, H.2
Saito, T.3
-
17
-
-
84855450333
-
Cooperative enhancement of radiosensitivity after combined treatment of 17-(allylamino)- 17-demethoxygeldanamycin and celecoxib in human lung and colon cancer cell lines
-
Kim, Y.M., and Pyo, H. (2012). Cooperative enhancement of radiosensitivity after combined treatment of 17-(allylamino)- 17-demethoxygeldanamycin and celecoxib in human lung and colon cancer cell lines. DNA Cell Biol 31, 15-29
-
(2012)
DNA Cell Biol
, vol.31
, pp. 15-29
-
-
Kim, Y.M.1
Pyo, H.2
-
18
-
-
33644868422
-
Growth factor withdrawal and apoptosis: The middle game
-
DOI 10.1016/j.molcel.2006.03.005, PII S1097276506001481
-
Letai, A. (2006). Growth factor withdrawal and apoptosis: The middle game. Mol Cell 21, 728-730 (Pubitemid 43376121)
-
(2006)
Molecular Cell
, vol.21
, Issue.6
, pp. 728-730
-
-
Letai, A.1
-
19
-
-
2342618936
-
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
-
Liang, J., and Slingerland, J.M. (2003). Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2, 339-345
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
20
-
-
84863786833
-
TH-302, a hypoxiaactivated prodrug with broad in vivo preclinical combination therapy efficacy: Optimization of dosing regimens and schedules
-
Liu, Q., Sun, J.D., Wang, J., et al. (2012). TH-302, a hypoxiaactivated prodrug with broad in vivo preclinical combination therapy efficacy: Optimization of dosing regimens and schedules. Cancer Chemother Pharmacol 69, 1487-1498
-
(2012)
Cancer Chemother Pharmacol
, vol.69
, pp. 1487-1498
-
-
Liu, Q.1
Sun, J.D.2
Wang, J.3
-
21
-
-
44649196585
-
Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts
-
Lu, P.Z., Lai, C.Y., and Chan, W.H. (2008). Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts. Int J Mol Sci 9, 698-718
-
(2008)
Int J Mol Sci
, vol.9
, pp. 698-718
-
-
Lu, P.Z.1
Lai, C.Y.2
Chan, W.H.3
-
22
-
-
65549147264
-
DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation
-
Munoz, M.J., Perez Santangelo, M.S., Paronetto, M.P., et al. (2009). DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. Cell 137, 708-720
-
(2009)
Cell
, vol.137
, pp. 708-720
-
-
Munoz, M.J.1
Perez Santangelo, M.S.2
Paronetto, M.P.3
-
23
-
-
68749095178
-
Amiloride derivatives induce apoptosis by depleting ER Ca(2 +) stores in vascular endothelial cells
-
Park, K.S., Poburko, D., Wollheim, C.B., et al. (2009). Amiloride derivatives induce apoptosis by depleting ER Ca(2 +) stores in vascular endothelial cells. Br J Pharmacol 156, 1296-1304
-
(2009)
Br J Pharmacol
, vol.156
, pp. 1296-1304
-
-
Park, K.S.1
Poburko, D.2
Wollheim, C.B.3
-
24
-
-
84858753779
-
Involvement of p53 in gemcitabine mediated cytotoxicity and radiosensitivity in breast cancer cell lines
-
Salem, S.D., Abou-Tarboush, F.M., Saeed, N.M., et al. (2012). Involvement of p53 in gemcitabine mediated cytotoxicity and radiosensitivity in breast cancer cell lines. Gene 498, 300-307
-
(2012)
Gene
, vol.498
, pp. 300-307
-
-
Salem, S.D.1
Abou-Tarboush, F.M.2
Saeed, N.M.3
-
25
-
-
21244439380
-
Regulation of apoptosis by alternative pre-mRNA splicing
-
DOI 10.1016/j.molcel.2005.05.026, PII S1097276505013754
-
Schwerk, C., and Schulze-Osthoff, K. (2005). Regulation of apoptosis by alternative pre-mRNA splicing. Mol Cell 19, 1-13 (Pubitemid 40884653)
-
(2005)
Molecular Cell
, vol.19
, Issue.1
, pp. 1-13
-
-
Schwerk, C.1
Schulze-Osthoff, K.2
-
26
-
-
80053369101
-
Acquired radioresistance of cancer and the AKT/GSK3beta/cyclin D1 overexpression cycle
-
Shimura, T. (2011). Acquired radioresistance of cancer and the AKT/GSK3beta/cyclin D1 overexpression cycle. J Radiat Res (Tokyo) 52, 539-544
-
(2011)
J Radiat Res (Tokyo)
, Issue.52
, pp. 539-544
-
-
Shimura, T.1
-
27
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp, R., Mason, W.P., van den Bent, M.J., et al. (2005). Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352, 987-996 (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
28
-
-
79251613020
-
Biomarkers in rare disorders: The experience with spinal muscular atrophy
-
Tiziano, F.D., Neri, G., and Brahe, C. (2010). Biomarkers in rare disorders: The experience with spinal muscular atrophy. Int J Mol Sci 12, 24-38
-
(2010)
Int J Mol Sci
, vol.12
, pp. 24-38
-
-
Tiziano, F.D.1
Neri, G.2
Brahe, C.3
-
29
-
-
84860863911
-
PI3K and mTOR signaling pathways in cancer: New data on targeted therapies
-
Willems, L., Tamburini, J., Chapuis, N., et al. (2012). PI3K and mTOR signaling pathways in cancer: New data on targeted therapies. Curr Oncol Rep 14, 129-138
-
(2012)
Curr Oncol Rep
, vol.14
, pp. 129-138
-
-
Willems, L.1
Tamburini, J.2
Chapuis, N.3
-
30
-
-
84860132805
-
Structural and functional characterization of two alternative splicing variants of mouse endothelial cell-specific chemotaxis regulator (ECSCR
-
Wu, W., Shi, C., Ma, F., et al. (2012). Structural and functional characterization of two alternative splicing variants of mouse endothelial cell-specific chemotaxis regulator (ECSCR). Int J Mol Sci 13, 4920-4936
-
(2012)
Int J Mol Sci
, vol.13
, pp. 4920-4936
-
-
Wu, W.1
Shi, C.2
Ma, F.3
-
31
-
-
84871704051
-
High density lipoprotein protects mesenchymal stem cells from oxidative stressinduced apoptosis via activation of the PI3K/Akt pathway and suppression of reactive oxygen species
-
Xu, J., Qian, J., Xie, X., et al. (2012). High density lipoprotein protects mesenchymal stem cells from oxidative stressinduced apoptosis via activation of the PI3K/Akt pathway and suppression of reactive oxygen species. Int J Mol Sci 13, 17104-17120
-
(2012)
Int J Mol Sci
, vol.13
, pp. 17104-17120
-
-
Xu, J.1
Qian, J.2
Xie, X.3
-
32
-
-
84870558434
-
Necrosis is not induced by gadolinium neutron capture in glioblastoma multiforme cells
-
Yasui, L., and Owens, K. (2012). Necrosis is not induced by gadolinium neutron capture in glioblastoma multiforme cells. Int J Radiat Biol 88, 980-990
-
(2012)
Int J Radiat Biol
, vol.88
, pp. 980-990
-
-
Yasui, L.1
Owens, K.2
-
33
-
-
77649104750
-
4beta- Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest
-
Yen, C.Y., Chiu, C.C., Chang, F.R., et al. (2010). 4beta- Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. BMC Cancer 10, 46
-
(2010)
BMC Cancer
, vol.10
, pp. 46
-
-
Yen, C.Y.1
Chiu, C.C.2
Chang, F.R.3
|