메뉴 건너뛰기




Volumn 133, Issue , 2013, Pages 15-33

Future of medicine: Models in predictive diagnostics and personalized medicine

Author keywords

Distributed computing; Health care revolution; High throughput data analysis; Nonlinear information and communication technology; Personalized medicine; Predictive model; Systems medicine; Virtual human

Indexed keywords

ARTICLE; EQUIPMENT; HEALTH CARE DELIVERY; HUMAN; METHODOLOGY; MOLECULAR PATHOLOGY; PERSONALIZED MEDICINE;

EID: 84882940713     PISSN: 07246145     EISSN: None     Source Type: Book Series    
DOI: 10.1007/10_2012_176     Document Type: Article
Times cited : (22)

References (58)
  • 1
    • 2042437650 scopus 로고    scopus 로고
    • Human genome-initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium
    • International Human Genome Sequencing Consortium Eric S. Lander et al (2001) Human genome-initial sequencing and analysis of the human genome. Nature 409:860-921
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1
  • 2
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter JC et al (2001) The sequence of the human genome. Science 291(5507):1304-1351
    • (2001) Science , vol.291 , Issue.5507 , pp. 1304-1351
    • Venter, J.C.1
  • 3
    • 77953397764 scopus 로고    scopus 로고
    • Systems medicine: The future of medical genomics and healthcare
    • Auffray C, Chen Z, Hood L (2009) Systems medicine: the future of medical genomics and healthcare. Genome Med 1(1):2
    • (2009) Genome Med , vol.1 , Issue.1 , pp. 2
    • Auffray, C.1    Chen, Z.2    Hood, L.3
  • 4
    • 84883010272 scopus 로고    scopus 로고
    • ITFoM: IT future of medicine-an IT revolution in medicine and health care
    • ITFoM Consortium
    • ITFoM Consortium (2011) ITFoM: IT future of medicine-an IT revolution in medicine and health care. ERCIM News 87:15
    • (2011) ERCIM News , vol.87 , pp. 15
  • 5
    • 84870560360 scopus 로고    scopus 로고
    • Role of genomics on the path to personalized medicine
    • doi:10.1016/j.metabol.2012.08.023
    • Tremblay J, Hamet P (2012) Role of genomics on the path to personalized medicine. Metabolism. doi:10.1016/j.metabol.2012.08.023
    • (2012) Metabolism
    • Tremblay, J.1    Hamet, P.2
  • 6
    • 27444434741 scopus 로고    scopus 로고
    • Genomic medicine: Genetic variation and its impact on the future of health care
    • Willard HF, Angrist M, Ginsburg GS (2005) Genomic medicine: genetic variation and its impact on the future of health care. Philos Trans R Soc Lond B Biol Sci 360(1460): 1543-1550
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , Issue.1460 , pp. 1543-1550
    • Willard, H.F.1    Angrist, M.2    Ginsburg, G.S.3
  • 7
    • 78649487695 scopus 로고    scopus 로고
    • Overview of personalized medicine in the disease genomic era
    • Hong KW, Oh B (2010) Overview of personalized medicine in the disease genomic era. BMB Rep 43(10):643-648
    • (2010) BMB Rep , vol.43 , Issue.10 , pp. 643-648
    • Hong, K.W.1    Oh, B.2
  • 8
    • 70449465250 scopus 로고    scopus 로고
    • Genomic and personalized medicine: Foundations and applications
    • Ginsburg GS, Willard HF (2009) Genomic and personalized medicine: foundations and applications. Transl Res 154(6):277-287
    • (2009) Transl Res , vol.154 , Issue.6 , pp. 277-287
    • Ginsburg, G.S.1    Willard, H.F.2
  • 10
    • 0034844646 scopus 로고    scopus 로고
    • Clinical application of pharmacogenetics
    • Spear BB, Heath-Chiozzi M, Huff J (2001) Clinical application of pharmacogenetics. Trends Mol Med 7(5):201-204
    • (2001) Trends Mol Med , vol.7 , Issue.5 , pp. 201-204
    • Spear, B.B.1    Heath-Chiozzi, M.2    Huff, J.3
  • 11
    • 84865429505 scopus 로고    scopus 로고
    • A personal view on systems medicine and the emergence of proactive P4 medicine: Predictive, preventive, personalized and participatory
    • Hood L, Flores M (2012) A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory. N Biotechnol 29(6):613-624
    • (2012) N Biotechnol , vol.29 , Issue.6 , pp. 613-624
    • Hood, L.1    Flores, M.2
  • 12
    • 78650323671 scopus 로고    scopus 로고
    • Predictive, preventive, personalized and participatory medicine: Back to the future
    • Auffray C, Charron D, Hood L (2012) Predictive, preventive, personalized and participatory medicine: back to the future. Genome Med 2(8):57
    • (2012) Genome Med , vol.2 , Issue.8 , pp. 57
    • Auffray, C.1    Charron, D.2    Hood, L.3
  • 13
    • 77954127988 scopus 로고    scopus 로고
    • Systems biology and the discovery of diagnostic biomarkers
    • Wang K, Lee I, Carlson G, Hood L, Galas D (2012) Systems biology and the discovery of diagnostic biomarkers. Dis Markers 28(4):199-207
    • (2012) Dis Markers , vol.28 , Issue.4 , pp. 199-207
    • Wang, K.1    Lee, I.2    Carlson, G.3    Hood, L.4    Galas, D.5
  • 15
    • 70449209123 scopus 로고
    • On protein synthesis
    • Crick FHC (1958) On protein synthesis. Symp Soc Exp Biol XII:139-163
    • (1958) Symp Soc Exp Biol , vol.12 , pp. 139-163
    • Crick, F.H.C.1
  • 16
    • 0014937223 scopus 로고
    • Central dogma of molecular biology
    • Crick F (1970) Central dogma of molecular biology. Nature 227(5258):561-563
    • (1970) Nature , vol.227 , Issue.5258 , pp. 561-563
    • Crick, F.1
  • 17
    • 77955505357 scopus 로고    scopus 로고
    • Protein-protein interactions essentials: Key concepts to building and analyzing interactome networks
    • De Las Rivas J, Fontanillo C (2010) Protein-protein interactions essentials: key concepts to building and analyzing interactome networks. PLoS Comput Biol 6(6):e1000807
    • (2010) PLoS Comput Biol , vol.6 , Issue.6
    • de Las Rivas, J.1    Fontanillo, C.2
  • 18
    • 52049096212 scopus 로고    scopus 로고
    • Move over proteomics, here comes glycomics
    • Srivastava S (2008) Move over proteomics, here comes glycomics. J Proteome Res 7(5):1799
    • (2008) J Proteome Res , vol.7 , Issue.5 , pp. 1799
    • Srivastava, S.1
  • 19
    • 33947192955 scopus 로고    scopus 로고
    • Comparison of the methods for profiling glycoprotein glycans-HUPO Human Disease Glycomics/Proteome Initiative multiinstitutional study
    • Wada J, Azadi P, Costello CE et al (2007) Comparison of the methods for profiling glycoprotein glycans-HUPO Human Disease Glycomics/Proteome Initiative multiinstitutional study. Glycobiology 17(4):411-422
    • (2007) Glycobiology , vol.17 , Issue.4 , pp. 411-422
    • Wada, J.1    Azadi, P.2    Costello, C.E.3
  • 20
    • 67650713930 scopus 로고    scopus 로고
    • The chemical biology of protein phosphorylation
    • Tarrant MK, Cole PA (2009) The chemical biology of protein phosphorylation. Annu Rev Biochem 78:797-825
    • (2009) Annu Rev Biochem , vol.78 , pp. 797-825
    • Tarrant, M.K.1    Cole, P.A.2
  • 22
    • 79951475133 scopus 로고    scopus 로고
    • A decade's perspective on DNA sequencing technology
    • Mardis ER (2011) A decade's perspective on DNA sequencing technology. Nature 470(7333):198-203
    • (2011) Nature , vol.470 , Issue.7333 , pp. 198-203
    • Mardis, E.R.1
  • 23
    • 58049117061 scopus 로고    scopus 로고
    • Reading the metabolic fine print. The application of metabolomics to diagnostics, drug research and nutrition might be integral to improved health and personalized medicine
    • Hunter P (2009) Reading the metabolic fine print. The application of metabolomics to diagnostics, drug research and nutrition might be integral to improved health and personalized medicine. EMBO Rep 10(1):20-23
    • (2009) EMBO Rep , vol.10 , Issue.1 , pp. 20-23
    • Hunter, P.1
  • 28
    • 33646443942 scopus 로고    scopus 로고
    • Recent developments and future trends in nuclear medicine instrumentation
    • Zaidi H (2006) Recent developments and future trends in nuclear medicine instrumentation. Z Med Phys 16(1):5-17
    • (2006) Z Med Phys , vol.16 , Issue.1 , pp. 5-17
    • Zaidi, H.1
  • 29
    • 68849097549 scopus 로고    scopus 로고
    • Advances in multimodality molecular imaging
    • Zaidi H, Prasad R (2009) Advances in multimodality molecular imaging. J Med Phys 34(3):122-128
    • (2009) J Med Phys , vol.34 , Issue.3 , pp. 122-128
    • Zaidi, H.1    Prasad, R.2
  • 30
    • 46849085176 scopus 로고    scopus 로고
    • Imaging and cancer: A review
    • Fass L (2008) Imaging and cancer: a review. Mol Oncol 2:115-152
    • (2008) Mol Oncol , vol.2 , pp. 115-152
    • Fass, L.1
  • 31
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function and diversity of the healthy human microbiome
    • Human Microbiome Project Consortium
    • Human Microbiome Project Consortium (2012) Structure, function and diversity of the healthy human microbiome. Nature 486(7402):207-214
    • (2012) Nature , vol.486 , Issue.7402 , pp. 207-214
  • 32
    • 84861961018 scopus 로고    scopus 로고
    • Tackling the microbiome
    • Hood L (2012) Tackling the microbiome. Science 336(6086):1209
    • (2012) Science , vol.336 , Issue.6086 , pp. 1209
    • Hood, L.1
  • 38
    • 77149146490 scopus 로고    scopus 로고
    • Physiologically based modelling and prediction of drug interactions
    • Bois FY (2010) Physiologically based modelling and prediction of drug interactions. Basic Clin Pharmacol Toxicol 106(3):154-161
    • (2010) Basic Clin Pharmacol Toxicol , vol.106 , Issue.3 , pp. 154-161
    • Bois, F.Y.1
  • 40
    • 77956651201 scopus 로고    scopus 로고
    • Biochemical network-based drug-target prediction
    • Klipp E, Wade RC, Kummer U (2010) Biochemical network-based drug-target prediction. Curr Opin Biotechnol 21(4):511-516
    • (2010) Curr Opin Biotechnol , vol.21 , Issue.4 , pp. 511-516
    • Klipp, E.1    Wade, R.C.2    Kummer, U.3
  • 41
    • 33745588546 scopus 로고    scopus 로고
    • The limits of reductionism in medicine: Could systems biology offer an alternative?
    • Ahn AC, Tewari M, Poon CS, Phillips RS (2006) The limits of reductionism in medicine: could systems biology offer an alternative? PLoS Med 3(6):e208
    • (2006) PLoS Med , vol.3 , Issue.6
    • Ahn, A.C.1    Tewari, M.2    Poon, C.S.3    Phillips, R.S.4
  • 42
    • 0036941857 scopus 로고    scopus 로고
    • Looking beyond the details: A rise in system-oriented approaches in genetics and molecular biology
    • Kitano H (2002) Looking beyond the details: a rise in system-oriented approaches in genetics and molecular biology. Curr Genet 41:1-10
    • (2002) Curr Genet , vol.41 , pp. 1-10
    • Kitano, H.1
  • 43
    • 7644238181 scopus 로고    scopus 로고
    • Biological robustness
    • Kitano H (2004) Biological robustness. Nat Rev Genet 5:826-837
    • (2004) Nat Rev Genet , vol.5 , pp. 826-837
    • Kitano, H.1
  • 45
    • 84858402950 scopus 로고    scopus 로고
    • A revolution in healthcare: Challenges and opportunities for personalized medicine
    • for The IT Future of Medicine consortium
    • Lehrach H for The IT Future of Medicine consortium (2012) A revolution in healthcare: challenges and opportunities for personalized medicine. Pers Med 9(2):105-108
    • (2012) Pers Med , vol.9 , Issue.2 , pp. 105-108
    • Lehrach, H.1
  • 46
    • 79751534354 scopus 로고    scopus 로고
    • Molecular imaging in oncology: The acceptance of PET/CT and the emergence of MR/PET imaging
    • Schiepers C, Dahlbom M (2011) Molecular imaging in oncology: the acceptance of PET/CT and the emergence of MR/PET imaging. Eur Radiol 21(3):548-554
    • (2011) Eur Radiol , vol.21 , Issue.3 , pp. 548-554
    • Schiepers, C.1    Dahlbom, M.2
  • 47
    • 33646489152 scopus 로고    scopus 로고
    • Diagnostic value of systematic biopsy methods in the investigation of prostate cancer: A systematic review
    • Eichler K, Hempel S, Wilby J, Myers L, Bachmann LM, Kleijnen J (2006) Diagnostic value of systematic biopsy methods in the investigation of prostate cancer: a systematic review. J Urol 175(5):1605-1612
    • (2006) J Urol , vol.175 , Issue.5 , pp. 1605-1612
    • Eichler, K.1    Hempel, S.2    Wilby, J.3    Myers, L.4    Bachmann, L.M.5    Kleijnen, J.6
  • 48
    • 77953746656 scopus 로고    scopus 로고
    • Tridimensional vector animation from fetal MRI as a simulation of delivery
    • Ami O, Chabrot P, Rabischong B, Rocas D, Delmas V, Boyer L, Mage G (2010) Tridimensional vector animation from fetal MRI as a simulation of delivery. J Radiol 91(4):515-517
    • (2010) J Radiol , vol.91 , Issue.4 , pp. 515-517
    • Ami, O.1    Chabrot, P.2    Rabischong, B.3    Rocas, D.4    Delmas, V.5    Boyer, L.6    Mage, G.7
  • 50
    • 77956417789 scopus 로고    scopus 로고
    • Computational reconstruction of tissue-specific metabolic models: Application to human liver metabolism
    • Jerby L, Shlomi T, Ruppin E (2010) Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism. Mol Syst Biol 6:401
    • (2010) Mol Syst Biol , vol.6 , pp. 401
    • Jerby, L.1    Shlomi, T.2    Ruppin, E.3
  • 52
    • 84857656298 scopus 로고    scopus 로고
    • The "Virtual Patient" system: Modeling cancer using deep sequencing technologies for personalized cancer treatment
    • Kühn A, Lehrach H (2012) The "Virtual Patient" system: modeling cancer using deep sequencing technologies for personalized cancer treatment. J Cons Prot Food Safety 7(1):55-62
    • (2012) J Cons Prot Food Safety , vol.7 , Issue.1 , pp. 55-62
    • Kühn, A.1    Lehrach, H.2
  • 53
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks in cancer
    • Hanahan D, Weinberg RA (2000) The hallmarks in cancer. Cell 100(1):57-70
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 54
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks in cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks in cancer: the next generation. Cell 144(5):646-674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 56
    • 33845212250 scopus 로고    scopus 로고
    • Anticipating the 1, 000 dollar genome
    • Mardis ER (2006) Anticipating the 1, 000 dollar genome. Genome Biol 7(7):112
    • (2006) Genome Biol , vol.7 , Issue.7 , pp. 112
    • Mardis, E.R.1
  • 57
    • 61449109247 scopus 로고    scopus 로고
    • Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking
    • Swan M (2009) Emerging patient-driven health care models: an examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 6(2):492-525
    • (2009) Int J Environ Res Public Health , vol.6 , Issue.2 , pp. 492-525
    • Swan, M.1
  • 58
    • 80052164935 scopus 로고    scopus 로고
    • Deployment of distributed applications in wireless sensor networks
    • Pilloni V, Atzori L (2011) Deployment of distributed applications in wireless sensor networks. Sensors (Basel, Switzerland) 11(8):7395-7419
    • (2011) Sensors (Basel, Switzerland) , vol.11 , Issue.8 , pp. 7395-7419
    • Pilloni, V.1    Atzori, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.