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Volumn , Issue , 2010, Pages 76-83

Electroanalytical methods as tools for predictive drug metabolism studies

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EID: 84882871684     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.2174/978160805190811001010076     Document Type: Chapter
Times cited : (3)

References (86)
  • 1
    • 33846059783 scopus 로고    scopus 로고
    • Analytical Tools and Approaches for Metabolite Identification in Early Drug Discovery
    • Chen Y, Monshouwer M, Fitch W. Analytical Tools and Approaches for Metabolite Identification in Early Drug Discovery. Pharm Res 2007; 24(2): 248-257.
    • (2007) Pharm Res , vol.24 , Issue.2 , pp. 248-257
    • Chen, Y.1    Monshouwer, M.2    Fitch, W.3
  • 2
    • 18844373318 scopus 로고    scopus 로고
    • Role of Metabolism in Drug-Induced Idiosyncratic Hepatotoxicity
    • Walgren J L, Mitchell M D, Thompson D C. Role of Metabolism in Drug-Induced Idiosyncratic Hepatotoxicity. Crit Rev Toxicol 2005; 35(4): 325-361.
    • (2005) Crit Rev Toxicol , vol.35 , Issue.4 , pp. 325-361
    • Walgren, J.L.1    Mitchell, M.D.2    Thompson, D.C.3
  • 3
    • 20444465945 scopus 로고    scopus 로고
    • The impact of early ADME profiling on drug discovery and development strategy
    • Wang J, Urban L. The impact of early ADME profiling on drug discovery and development strategy. Drug Discov World 2004; fall: 73-86.
    • (2004) Drug Discov World , pp. 73-86
    • Wang, J.1    Urban, L.2
  • 4
    • 2342640748 scopus 로고    scopus 로고
    • Trends in early drug safety
    • Armer R E, Morris I D. Trends in early drug safety. Drug News Perspect 2004; 17(2): 143-148.
    • (2004) Drug News Perspect , vol.17 , Issue.2 , pp. 143-148
    • Armer, R.E.1    Morris, I.D.2
  • 5
    • 0036975222 scopus 로고    scopus 로고
    • ECVAM and pharmaceuticals
    • Vanparys P. ECVAM and pharmaceuticals. ATLA 2002; 30: 221-223.
    • (2002) ATLA , vol.30 , pp. 221-223
    • Vanparys, P.1
  • 7
    • 12844253069 scopus 로고    scopus 로고
    • From the Cover: Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses
    • Lee M-Y, Park C B, Dordick J S, Clark D S. From the Cover: Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses. PNAS 2005; 102(4): 983-987.
    • (2005) PNAS , vol.102 , Issue.4 , pp. 983-987
    • Lee, M.-Y.1    Park, C.B.2    Dordick, J.S.3    Clark, D.S.4
  • 8
    • 15944425080 scopus 로고    scopus 로고
    • Techniques: Application of systems biology to absorption, distribution, metabolism, excretion and toxicity
    • Ekins S, Nikolsky Y, Nikolskaya T. Techniques: Application of systems biology to absorption, distribution, metabolism, excretion and toxicity. Trends Pharmacol Sci 2005; 26(4): 202-209.
    • (2005) Trends Pharmacol Sci , vol.26 , Issue.4 , pp. 202-209
    • Ekins, S.1    Nikolsky, Y.2    Nikolskaya, T.3
  • 9
    • 0038278508 scopus 로고    scopus 로고
    • An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons
    • Brandon E F A, Raap C D, Meijerman I, Beijnen J H, Schellens J H M. An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons. Toxicol Appl Pharmacol 2003; 189(3): 233-246.
    • (2003) Toxicol Appl Pharmacol , vol.189 , Issue.3 , pp. 233-246
    • Brandon, E.F.A.1    Raap, C.D.2    Meijerman, I.3    Beijnen, J.H.4    Schellens, J.H.M.5
  • 10
    • 1542272438 scopus 로고    scopus 로고
    • Effects of EDTA on signal stability during electrochemical detection of acetaminophen
    • de Carvalho R M, Freire R S, Rath S, Kubota L T. Effects of EDTA on signal stability during electrochemical detection of acetaminophen. J Pharm Biomed Anal 2004; 34(5): 871-878.
    • (2004) J Pharm Biomed Anal , vol.34 , Issue.5 , pp. 871-878
    • De Carvalho, R.M.1    Freire, R.S.2    Rath, S.3    Kubota, L.T.4
  • 12
    • 0037258065 scopus 로고    scopus 로고
    • Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions
    • Jurva U, Wikström H V, Weidolf L, Bruins A P. Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions. Rapid Commun Mass Spectrom 2003; 17(8): 800-810.
    • (2003) Rapid Commun Mass Spectrom , vol.17 , Issue.8 , pp. 800-810
    • Jurva, U.1    Wikström, H.V.2    Weidolf, L.3    Bruins, A.P.4
  • 13
    • 68949086185 scopus 로고    scopus 로고
    • Environmentally Friendly Expeditious One-Pot Electrochemical Synthesis of Bis-Catechol-Thioether Metabolites of Ecstasy: in vitro Neurotoxic Effects in the Rat Hippocampus
    • Felim A, Neudörffer A, Monnet F P, Largeron M. Environmentally Friendly Expeditious One-Pot Electrochemical Synthesis of Bis-Catechol-Thioether Metabolites of Ecstasy: in vitro Neurotoxic Effects in the Rat Hippocampus. Int J Electrochem Sci 2008; 3: 266-281.
    • (2008) Int J Electrochem Sci , vol.3 , pp. 266-281
    • Felim, A.1    Neudörffer, A.2    Monnet, F.P.3    Largeron, M.4
  • 14
    • 34248589634 scopus 로고    scopus 로고
    • Bacterial Plate Assays and Electrochemical Methods: An Efficient Tandem for Evaluating the Ability of Catechol - Thioether Metabolites of MDMA ("Ecstasy") to Induce Toxic Effects through Redox-Cycling
    • Felim A, Urios A, Neudorffer A, Herrera G, Blanco M, Largeron M. Bacterial Plate Assays and Electrochemical Methods: An Efficient Tandem for Evaluating the Ability of Catechol - Thioether Metabolites of MDMA ("Ecstasy") to Induce Toxic Effects through Redox-Cycling. Chem Res Toxicol 2007; 20(4): 685-693.
    • (2007) Chem Res Toxicol , vol.20 , Issue.4 , pp. 685-693
    • Felim, A.1    Urios, A.2    Neudorffer, A.3    Herrera, G.4    Blanco, M.5    Largeron, M.6
  • 16
    • 1942504048 scopus 로고    scopus 로고
    • Biosensors for determination of total antioxidant capacity of phytotherapeutic integrators: comparison with other spectrophotometric, fluorimetric and voltammetric methods
    • Campanella L, Bonanni A, Bellantoni D, Tomassetti M. Biosensors for determination of total antioxidant capacity of phytotherapeutic integrators: comparison with other spectrophotometric, fluorimetric and voltammetric methods. J Pharm Biomed Anal 2004; 35(2): 303-320.
    • (2004) J Pharm Biomed Anal , vol.35 , Issue.2 , pp. 303-320
    • Campanella, L.1    Bonanni, A.2    Bellantoni, D.3    Tomassetti, M.4
  • 17
    • 4444359050 scopus 로고    scopus 로고
    • Comparison of fluorimetric, voltammetric and biosensor methods for the determination of total antioxidant capacity of drug products containing acetylsalicylic acid
    • Campanella L, Bonanni A, Bellantoni D, Favero G, Tomassetti M. Comparison of fluorimetric, voltammetric and biosensor methods for the determination of total antioxidant capacity of drug products containing acetylsalicylic acid. J Pharm Biomed Anal 2004; 36(1): 91-99.
    • (2004) J Pharm Biomed Anal , vol.36 , Issue.1 , pp. 91-99
    • Campanella, L.1    Bonanni, A.2    Bellantoni, D.3    Favero, G.4    Tomassetti, M.5
  • 18
    • 0034654255 scopus 로고    scopus 로고
    • The use of cyclic voltammetry for the evaluation of antioxidant capacity
    • Chevion S, Roberts M A, Chevion M. The use of cyclic voltammetry for the evaluation of antioxidant capacity. Free Radic Biol Med 2000; 28(6): 860-870.
    • (2000) Free Radic Biol Med , vol.28 , Issue.6 , pp. 860-870
    • Chevion, S.1    Roberts, M.A.2    Chevion, M.3
  • 19
    • 0031592275 scopus 로고    scopus 로고
    • Mediated electrochemistry of peroxidases-effects of variations in protein and mediator structures
    • Sadeghi S J, Gilardi G, Cass A E G. Mediated electrochemistry of peroxidases-effects of variations in protein and mediator structures. Biosens Bioelectron 1997; 12: 1191-1198.
    • (1997) Biosens Bioelectron , vol.12 , pp. 1191-1198
    • Sadeghi, S.J.1    Gilardi, G.2    Cass, A.E.G.3
  • 21
    • 0021734781 scopus 로고
    • Tentative correlation between the electrochemical oxidation of neuroleptics and their pharmacological properties
    • Kauffmann J-M, Vire J-C, Patriarche G J. Tentative correlation between the electrochemical oxidation of neuroleptics and their pharmacological properties. Bioelectrochem Bioenerg 1984; 12: 413-420.
    • (1984) Bioelectrochem Bioenerg , vol.12 , pp. 413-420
    • Kauffmann, J.-M.1    Vire, J.-C.2    Patriarche, G.J.3
  • 23
    • 0036535201 scopus 로고    scopus 로고
    • Advances in the Voltammetric Analysis of Small Biologically Relevant Compounds
    • Lawrence N S, Beckett E L, Davis J, Compton R G. Advances in the Voltammetric Analysis of Small Biologically Relevant Compounds. Anal Biochem 2002; 303(1): 1-16.
    • (2002) Anal Biochem , vol.303 , Issue.1 , pp. 1-16
    • Lawrence, N.S.1    Beckett, E.L.2    Davis, J.3    Compton, R.G.4
  • 24
    • 0035799725 scopus 로고    scopus 로고
    • Unusually large numbers of electrons for the oxidation of polyphenolic antioxidants
    • Hotta H, Sakamoto H, Nagano S, Osakai T, Tsujino Y. Unusually large numbers of electrons for the oxidation of polyphenolic antioxidants. Biochim Biophys Acta 2001; 1526(2): 159-167.
    • (2001) Biochim Biophys Acta , vol.1526 , Issue.2 , pp. 159-167
    • Hotta, H.1    Sakamoto, H.2    Nagano, S.3    Osakai, T.4    Tsujino, Y.5
  • 25
    • 3042565520 scopus 로고    scopus 로고
    • Voltammetric analysis of drugs
    • Abo El-Maali N. Voltammetric analysis of drugs. Bioelectrochem 2004; 64(1): 99-107.
    • (2004) Bioelectrochem , vol.64 , Issue.1 , pp. 99-107
    • Abo El-maali, N.1
  • 28
    • 65549107379 scopus 로고    scopus 로고
    • Voltammetric and spectral characterization of two flavonols for assaydependent antioxidant capacity
    • He J-B, Yuan S-J, Du J-Q, Hu X-R, Wang Y. Voltammetric and spectral characterization of two flavonols for assaydependent antioxidant capacity. Bioelectrochem 2009; 75(2): 110-116.
    • (2009) Bioelectrochem , vol.75 , Issue.2 , pp. 110-116
    • He, J.-B.1    Yuan, S.-J.2    Du, J.-Q.3    Hu, X-R.4    Wang, Y.5
  • 29
    • 0042563103 scopus 로고    scopus 로고
    • Phenothiazines drugs as redox mediators in horseradish peroxidase bioelectrocatalysis
    • Seradilla Razola S, Blankert B, Quarin G, Kauffmann J-M. Phenothiazines drugs as redox mediators in horseradish peroxidase bioelectrocatalysis. Anal. Lett. 2003; 36(9): 1819-1833.
    • (2003) Anal. Lett. , vol.36 , Issue.9 , pp. 1819-1833
    • Seradilla Razola, S.1    Blankert, B.2    Quarin, G.3    Kauffmann, J.-M.4
  • 30
    • 44849084454 scopus 로고    scopus 로고
    • Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds
    • Hillard E A, Caxico de Abreu F, Ferreira D C M, Jaouen G, Goulart M O F, Amatore C. Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds. Chem Commun 2008; 23: 2612-2628.
    • (2008) Chem Commun , vol.23 , pp. 2612-2628
    • Hillard, E.A.1    Caxico De Abreu, F.2    Ferreira, D.C.M.3    Jaouen, G.4    Goulart, M.O.F.5    Amatore, C.6
  • 32
    • 33947574296 scopus 로고    scopus 로고
    • Development of amperometric horseradish peroxidase based biosensors for clozapine and for the screening of thiol compounds
    • Yu D, Blankert B, Kauffmann J-M. Development of amperometric horseradish peroxidase based biosensors for clozapine and for the screening of thiol compounds. Biosens Bioelectron 2007; 22(11): 2707-2711.
    • (2007) Biosens Bioelectron , vol.22 , Issue.11 , pp. 2707-2711
    • Yu, D.1    Blankert, B.2    Kauffmann, J.-M.3
  • 33
    • 18944406318 scopus 로고    scopus 로고
    • Peroxidases: a role in the metabolism and side effects of drugs
    • Tafazoli S, O'Brien P J. Peroxidases: a role in the metabolism and side effects of drugs. Drug Discovery Today 2005; 10(9): 617-625.
    • (2005) Drug Discovery Today , vol.10 , Issue.9 , pp. 617-625
    • Tafazoli, S.1    O'Brien, P.J.2
  • 34
    • 0346250848 scopus 로고    scopus 로고
    • Idiosyncratic toxicity: the role of toxicophores and bioactivation
    • Williams D P, Park B K. Idiosyncratic toxicity: the role of toxicophores and bioactivation. Drug Discovery Today 2003; 8(22): 1044-1050.
    • (2003) Drug Discovery Today , vol.8 , Issue.22 , pp. 1044-1050
    • Williams, D.P.1    Park, B.K.2
  • 35
    • 21244505432 scopus 로고    scopus 로고
    • Prediction of clozapine metabolism by on-line electrochemistry/liquid chromatography/mass spectrometry
    • van Leeuw S M, Blankert B, Kauffmann J-M, Karst U. Prediction of clozapine metabolism by on-line electrochemistry/liquid chromatography/mass spectrometry. Anal. Bioanal.Chem 2005; 382: 742-750.
    • (2005) Anal. Bioanal.Chem , vol.382 , pp. 742-750
    • Van Leeuw, S.M.1    Blankert, B.2    Kauffmann, J.-M.3    Karst, U.4
  • 37
    • 0024534945 scopus 로고
    • Reduction potentials of anthelmintic drugs: Possible relationship to activity
    • Kovacic P, Ames J R, Rector D L, Jawdosiuk M, Ryan M D. Reduction potentials of anthelmintic drugs: Possible relationship to activity. Free Radic Biol Med 1989; 6(2): 131-139.
    • (1989) Free Radic Biol Med , vol.6 , Issue.2 , pp. 131-139
    • Kovacic, P.1    Ames, J.R.2    Rector, D.L.3    Jawdosiuk, M.4    Ryan, M.D.5
  • 38
    • 0036361472 scopus 로고    scopus 로고
    • On-line electrochemistry - MS and related techniques
    • Diehl G, Karst U. On-line electrochemistry - MS and related techniques. Anal Bioanal Chem 2002; 373(6): 390-398.
    • (2002) Anal Bioanal Chem , vol.373 , Issue.6 , pp. 390-398
    • Diehl, G.1    Karst, U.2
  • 39
    • 10044254190 scopus 로고    scopus 로고
    • ADME/TOx Profiling using coulometric electrochemistry and electrospray ionization mass spectrometry
    • Gamache P, Smith R, McCarthy R, Waraska J, Acworth I. ADME/TOx Profiling using coulometric electrochemistry and electrospray ionization mass spectrometry. Spectroscopy 2003; 18(6): 14-21.
    • (2003) Spectroscopy , vol.18 , Issue.6 , pp. 14-21
    • Gamache, P.1    Smith, R.2    McCarthy, R.3    Waraska, J.4    Acworth, I.5
  • 40
    • 10444223168 scopus 로고    scopus 로고
    • Pharmaceutical oxidative stability profiling with high-throughput voltammetry
    • Gamache P, McCarthy R, Waraska J, Acworth I. Pharmaceutical oxidative stability profiling with high-throughput voltammetry. American Laboratory 2003; 35: 21-25.
    • (2003) American Laboratory , vol.35 , pp. 21-25
    • Gamache, P.1    McCarthy, R.2    Waraska, J.3    Acworth, I.4
  • 42
    • 84882891633 scopus 로고    scopus 로고
    • Drug metabolism studies aided by redox chemistry
    • Asa D. Drug metabolism studies aided by redox chemistry. Genetic Engineering News 2004; 24(12).
    • (2004) Genetic Engineering News , vol.24 , Issue.12
    • Asa, D.1
  • 43
    • 33646245679 scopus 로고    scopus 로고
    • The influence of the thin-layer flow cell design on the mass spectra when coupling electrochemistry to electrospray ionisation mass spectrometry
    • Zettersten C, Lomoth R, Hammarström L, Sjöberg P J R, Nyholm L. The influence of the thin-layer flow cell design on the mass spectra when coupling electrochemistry to electrospray ionisation mass spectrometry. J Electroanal Chem 2006; 590(1): 90-99.
    • (2006) J Electroanal Chem , vol.590 , Issue.1 , pp. 90-99
    • Zettersten, C.1    Lomoth, R.2    Hammarström, L.3    Sjöberg, P.J.R.4    Nyholm, L.5
  • 44
    • 0037594507 scopus 로고    scopus 로고
    • Electrochemical oxidation and cleavage of peptides analyzed with on-line mass spectrometric detection
    • Permentier H P, Jurva U, Barroso B, Bruins A P. Electrochemical oxidation and cleavage of peptides analyzed with on-line mass spectrometric detection. Rapid Commun Mass Spectrom 2003; 17(14): 1585-1592.
    • (2003) Rapid Commun Mass Spectrom , vol.17 , Issue.14 , pp. 1585-1592
    • Permentier, H.P.1    Jurva, U.2    Barroso, B.3    Bruins, A.P.4
  • 45
    • 40049111087 scopus 로고    scopus 로고
    • Electrochemistry-Mass Spectrometry in Drug Metabolism and Protein Research
    • Permentier H P, Bruins A P, Bischoff R. Electrochemistry-Mass Spectrometry in Drug Metabolism and Protein Research. Mini Rev Med Chem 2008; 8(1): 46-56.
    • (2008) Mini Rev Med Chem , vol.8 , Issue.1 , pp. 46-56
    • Permentier, H.P.1    Bruins, A.P.2    Bischoff, R.3
  • 46
    • 67449133537 scopus 로고    scopus 로고
    • Electrochemistry meets enzymes: instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene
    • Lohmann W, Karst U. Electrochemistry meets enzymes: instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene. Anal Bioanal Chem 2009; 394(5): 1341-1348.
    • (2009) Anal Bioanal Chem , vol.394 , Issue.5 , pp. 1341-1348
    • Lohmann, W.1    Karst, U.2
  • 47
    • 33751182073 scopus 로고    scopus 로고
    • Simulation of the detoxification of paracetamol using on-line electrochemistry/liquid chromatography/mass spectrometry
    • Lohmann W, Karst U. Simulation of the detoxification of paracetamol using on-line electrochemistry/liquid chromatography/mass spectrometry. Anal Bioanal Chem 2006; 386(6): 1701-1708.
    • (2006) Anal Bioanal Chem , vol.386 , Issue.6 , pp. 1701-1708
    • Lohmann, W.1    Karst, U.2
  • 48
    • 34250731278 scopus 로고    scopus 로고
    • Development and Evaluation of an Electrochemical Method for Studying Reactive Phase-I Metabolites: Correlation to in Vitro Drug Metabolism
    • Madsen K G, Olsen J, Skonberg C, Hansen S H, Jurva U. Development and Evaluation of an Electrochemical Method for Studying Reactive Phase-I Metabolites: Correlation to in Vitro Drug Metabolism. Chem Res Toxicol 2007; 20(5): 821-831.
    • (2007) Chem Res Toxicol , vol.20 , Issue.5 , pp. 821-831
    • Madsen, K.G.1    Olsen, J.2    Skonberg, C.3    Hansen, S.H.4    Jurva, U.5
  • 49
    • 0141482222 scopus 로고    scopus 로고
    • Analysis of Phenothiazine and Its Derivatives Using LC/Electrochemistry/MS and LC/Electrochemistry/Fluorescence
    • Hayen H, Karst U. Analysis of Phenothiazine and Its Derivatives Using LC/Electrochemistry/MS and LC/Electrochemistry/Fluorescence. Anal Chem 2003; 75(18): 4833-4840.
    • (2003) Anal Chem , vol.75 , Issue.18 , pp. 4833-4840
    • Hayen, H.1    Karst, U.2
  • 50
    • 33745790666 scopus 로고    scopus 로고
    • Investigation of the electrochemical oxidation products of zotepine and their fragmentation using on-line electrochemistry/electrospray ionization mass spectrometry
    • Nozaki K, Kitagawa H, Kimura S, Kagayama A, Arakawa R. Investigation of the electrochemical oxidation products of zotepine and their fragmentation using on-line electrochemistry/electrospray ionization mass spectrometry. J Mass Spectrom 2006; 41(5): 606-612.
    • (2006) J Mass Spectrom , vol.41 , Issue.5 , pp. 606-612
    • Nozaki, K.1    Kitagawa, H.2    Kimura, S.3    Kagayama, A.4    Arakawa, R.5
  • 51
    • 57749188066 scopus 로고    scopus 로고
    • On-Line Electrochemistry/Liquid Chromatography/Mass Spectrometry for the Simulation of Pesticide Metabolism
    • Lohmann W, Dötzer R, Gütter G, Van Leeuwen S M, Karst U. On-Line Electrochemistry/Liquid Chromatography/Mass Spectrometry for the Simulation of Pesticide Metabolism. J Am Soc Mass Spectrom 2009; 20(1): 138-145.
    • (2009) J Am Soc Mass Spectrom , vol.20 , Issue.1 , pp. 138-145
    • Lohmann, W.1    Dötzer, R.2    Gütter, G.3    Van Leeuwen, S.M.4    Karst, U.5
  • 52
    • 34548577031 scopus 로고    scopus 로고
    • Generation and Identification of Reactive Metabolites by Electrochemistry and Immobilized Enzymes Coupled On-Line to Liquid Chromatography/Mass Spectrometry
    • Lohmann W, Karst U. Generation and Identification of Reactive Metabolites by Electrochemistry and Immobilized Enzymes Coupled On-Line to Liquid Chromatography/Mass Spectrometry. Anal Chem 2007; 79(17): 6831-6839.
    • (2007) Anal Chem , vol.79 , Issue.17 , pp. 6831-6839
    • Lohmann, W.1    Karst, U.2
  • 53
    • 0000634947 scopus 로고    scopus 로고
    • A Thin-Layer Electrochemical Flow Cell Coupled On-Line with Electrospray-Mass Spectrometry for the Study of Biological Redox Reactions
    • Deng H, Berkel G J V. A Thin-Layer Electrochemical Flow Cell Coupled On-Line with Electrospray-Mass Spectrometry for the Study of Biological Redox Reactions. Electroanal 1999; 11(12): 857-865.
    • (1999) Electroanal , vol.11 , Issue.12 , pp. 857-865
    • Deng, H.1    Berkel, G.J.V.2
  • 54
    • 11144358239 scopus 로고    scopus 로고
    • A Setup for the Coupling of a Thin-Layer Electrochemical Flow Cell to Electrospray Mass Spectrometry
    • Bokman C F, Zettersten C, Sjober P J R, Nyholm L. A Setup for the Coupling of a Thin-Layer Electrochemical Flow Cell to Electrospray Mass Spectrometry. Anal Chem 2004; 76(7): 2017-2024.
    • (2004) Anal Chem , vol.76 , Issue.7 , pp. 2017-2024
    • Bokman, C.F.1    Zettersten, C.2    Sjober, P.J.R.3    Nyholm, L.4
  • 55
    • 0034100506 scopus 로고    scopus 로고
    • In vitro mimicry of metabolic oxidation reactions by electrochemistry/mass spectrometry
    • Jurva U, Wikström H V, Bruins A P. In vitro mimicry of metabolic oxidation reactions by electrochemistry/mass spectrometry. Rapid Commun Mass Spectrom 2000; 14(6): 529-533.
    • (2000) Rapid Commun Mass Spectrom , vol.14 , Issue.6 , pp. 529-533
    • Jurva, U.1    Wikström, H.V.2    Bruins, A.P.3
  • 56
    • 34547165961 scopus 로고    scopus 로고
    • Mimicry of phase I drug metabolism - novel methods for metabolite characterization and synthesis
    • Johansson T, Weidolf L, Jurva U. Mimicry of phase I drug metabolism - novel methods for metabolite characterization and synthesis. Rapid Commun Mass Spectrom 2007; 21(14): 2323-2331.
    • (2007) Rapid Commun Mass Spectrom , vol.21 , Issue.14 , pp. 2323-2331
    • Johansson, T.1    Weidolf, L.2    Jurva, U.3
  • 57
    • 3242775486 scopus 로고    scopus 로고
    • Product analysis of caffeic acid oxidation by on-line electrochemistry/electrospray ionization mass spectrometry
    • Arakawa R, Yamaguchi M, Hotta H, Osakai T, Kimoto T. Product analysis of caffeic acid oxidation by on-line electrochemistry/electrospray ionization mass spectrometry. J Am Soc Mass Spectrom 2004; 15(8): 1228-1236.
    • (2004) J Am Soc Mass Spectrom , vol.15 , Issue.8 , pp. 1228-1236
    • Arakawa, R.1    Yamaguchi, M.2    Hotta, H.3    Osakai, T.4    Kimoto, T.5
  • 58
    • 62249162146 scopus 로고    scopus 로고
    • Metabolic studies of tetrazepam based on electrochemical simulation in comparison to in vivo and in vitro methods
    • Baumann A, Lohmann W, Schubert B, Oberacher H, Karst U. Metabolic studies of tetrazepam based on electrochemical simulation in comparison to in vivo and in vitro methods. J Chromatogr A 2009; 1216(15): 3192-3198.
    • (2009) J Chromatogr A , vol.1216 , Issue.15 , pp. 3192-3198
    • Baumann, A.1    Lohmann, W.2    Schubert, B.3    Oberacher, H.4    Karst, U.5
  • 60
    • 0034680498 scopus 로고    scopus 로고
    • Biosensors: Sense and sensitivity
    • Turner A P F. Biosensors: Sense and sensitivity. Science 2000; 290: 1315-1317.
    • (2000) Science , vol.290 , pp. 1315-1317
    • Turner A, P.F.1
  • 62
    • 0141758332 scopus 로고    scopus 로고
    • Biosensor profiling of molecular interactions in pharmacology
    • Cooper M A. Biosensor profiling of molecular interactions in pharmacology. Curr Opin Pharmacol 2003; 3(5): 557-562.
    • (2003) Curr Opin Pharmacol , vol.3 , Issue.5 , pp. 557-562
    • Cooper, M.A.1
  • 63
    • 0034250562 scopus 로고    scopus 로고
    • Application of P450s for biosensing: combination of biotechnology and electrochemistry
    • Hara M. Application of P450s for biosensing: combination of biotechnology and electrochemistry. Mater Sci Eng, C 2000; 12(1-2): 103-109.
    • (2000) Mater Sci Eng, C , vol.12 , Issue.1-2 , pp. 103-109
    • Hara, M.1
  • 64
    • 0038054179 scopus 로고    scopus 로고
    • An amperometric biosensor with human CYP3A4 as a novel drug screening tool
    • Joseph S, Rusling J F, Lvov Y M, Friedberg T, Fuhr U. An amperometric biosensor with human CYP3A4 as a novel drug screening tool. Biochem Pharmacol 2003; 65(11): 1817-1826.
    • (2003) Biochem Pharmacol , vol.65 , Issue.11 , pp. 1817-1826
    • Joseph, S.1    Rusling, J.F.2    Lvov, Y.M.3    Friedberg, T.4    Fuhr, U.5
  • 66
    • 0032425913 scopus 로고    scopus 로고
    • Drug metabolism biosensors: electrochemical reactivities of cytochrome P450cam immobilised in synthetic vesicular systems
    • Iwuoha E I, Joseph S, Zhang Z, Smyth M R, Fuhr U, Ortiz de Montellano P R. Drug metabolism biosensors: electrochemical reactivities of cytochrome P450cam immobilised in synthetic vesicular systems. J Pharm Biomed Anal 1998; 17: 1101-1110.
    • (1998) J Pharm Biomed Anal , vol.17 , pp. 1101-1110
    • Iwuoha, E.I.1    Joseph, S.2    Zhang, Z.3    Smyth, M.R.4    Fuhr, U.5    Ortiz De Montellano, P.R.6
  • 67
    • 40649086027 scopus 로고    scopus 로고
    • Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing
    • Liu S, Peng L, Yang X, Wu Y, He L. Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing. Anal Biochem 2008; 375(2): 209-216.
    • (2008) Anal Biochem , vol.375 , Issue.2 , pp. 209-216
    • Liu, S.1    Peng, L.2    Yang, X.3    Wu, Y.4    He, L.5
  • 69
    • 17044388243 scopus 로고    scopus 로고
    • Electrochemical reduction of cytochrome P450 as an approach to the construction of biosensors and bioreactors
    • Shumyantseva V V, Bulko T V, Archakov A I. Electrochemical reduction of cytochrome P450 as an approach to the construction of biosensors and bioreactors. J Inorg Biochem 2005; 99(5): 1051-1063.
    • (2005) J Inorg Biochem , vol.99 , Issue.5 , pp. 1051-1063
    • Shumyantseva, V.V.1    Bulko, T.V.2    Archakov, A.I.3
  • 70
    • 2142654475 scopus 로고    scopus 로고
    • Some recents designs and developments of screenprinted carbon electrochemical sensors/biosensors for biomedical, environmental, and industrial analyses
    • Hart J P, Crew A, Crouch E, Honeychurch K C, Pemberton R M. Some recents designs and developments of screenprinted carbon electrochemical sensors/biosensors for biomedical, environmental, and industrial analyses. Ann. Lett. 2004; 37(5): 1-42.
    • (2004) Ann. Lett. , vol.37 , Issue.5 , pp. 1-42
    • Hart, J.P.1    Crew, A.2    Crouch, E.3    Honeychurch, K.C.4    Pemberton, R.M.5
  • 71
    • 19744379448 scopus 로고    scopus 로고
    • Cell-based biosensors and its application in biomedicine
    • Wang P, Xu G, Qin L, Xu Y, Li Y, Li R. Cell-based biosensors and its application in biomedicine. Sens Actuators, B 2005; 108(1-2): 576-584.
    • (2005) Sens Actuators, B , vol.108 , Issue.1-2 , pp. 576-584
    • Wang, P.1    Xu, G.2    Qin, L.3    Xu, Y.4    Li, Y.5    Li, R.6
  • 72
    • 0037419867 scopus 로고    scopus 로고
    • Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films
    • Zhou L, Yang J, Estavillo C, Stuart J D, Schenkman J B, Rusling J F. Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films. J Am Chem Soc 2003; 125(1431-1436).
    • (2003) J Am Chem Soc , vol.125 , Issue.1431-1436
    • Zhou, L.1    Yang, J.2    Estavillo, C.3    Stuart, J.D.4    Schenkman, J.B.5    Rusling, J.F.6
  • 73
    • 0034878255 scopus 로고    scopus 로고
    • Cellular biosensors for drug discovery
    • Durick K, Negulescu P. Cellular biosensors for drug discovery. Biosens Bioelectron 2001; 16(7-8): 587-592.
    • (2001) Biosens Bioelectron , vol.16 , Issue.7-8 , pp. 587-592
    • Durick, K.1    Negulescu, P.2
  • 74
    • 0042045214 scopus 로고    scopus 로고
    • Whole cell biosensors
    • Bousse L. Whole cell biosensors. Sens Actuators, B 1996; 34(1-3): 270-275.
    • (1996) Sens Actuators, B , vol.34 , Issue.1-3 , pp. 270-275
    • Bousse, L.1
  • 75
  • 78
    • 0036684258 scopus 로고    scopus 로고
    • Electrochemical DNA Biosensors Based on DNA-Drug Interactions
    • Erdem A, Ozsoz M. Electrochemical DNA Biosensors Based on DNA-Drug Interactions. Electroanal 2002; 14(14): 965-974.
    • (2002) Electroanal , vol.14 , Issue.14 , pp. 965-974
    • Erdem, A.1    Ozsoz, M.2
  • 79
    • 33746008739 scopus 로고    scopus 로고
    • Deoxyribonucleic acid (DNA) biosensors for environmental risk assessment and drug studies
    • Bagni G, Osella D, Sturchio E, Mascini M. Deoxyribonucleic acid (DNA) biosensors for environmental risk assessment and drug studies. Anal Chim Acta 2006; 573-574: 81-89.
    • (2006) Anal Chim Acta , vol.573-574 , pp. 81-89
    • Bagni, G.1    Osella, D.2    Sturchio, E.3    Mascini, M.4
  • 81
    • 0034194742 scopus 로고    scopus 로고
    • Detection od chemically induced DNA damage by drivative square wave voltammetry
    • Mbindyo J, Zhou L, Zhang Z, Stuart J D, Rusling J F. Detection od chemically induced DNA damage by drivative square wave voltammetry. Anal Chem 2000; 72: 2059-2065.
    • (2000) Anal Chem , vol.72 , pp. 2059-2065
    • Mbindyo, J.1    Zhou, L.2    Zhang, Z.3    Stuart, J.D.4    Rusling, J.F.5
  • 82
    • 2542571719 scopus 로고    scopus 로고
    • Applications of polyions filsm containing biomolecules to sensing toxicity
    • Rusling J F. Applications of polyions filsm containing biomolecules to sensing toxicity. Faraday Discuss 2000; 116: 77-87.
    • (2000) Faraday Discuss , vol.116 , pp. 77-87
    • Rusling, J.F.1
  • 86
    • 33748520250 scopus 로고    scopus 로고
    • A Peroxidase-Based Biosensor Supported by Nanoporous Magnetic Silica Microparticles for Acetaminophen Biotransformation and Inhibition Studies
    • Yu D, Renedo O D, Blankert B, Sima V, Sandulescu R, Arcos J, Kauffmann J-M. A Peroxidase-Based Biosensor Supported by Nanoporous Magnetic Silica Microparticles for Acetaminophen Biotransformation and Inhibition Studies. Electroanal 2006; 18(17): 1637-1642.
    • (2006) Electroanal , vol.18 , Issue.17 , pp. 1637-1642
    • Yu, D.1    Renedo, O.D.2    Blankert, B.3    Sima, V.4    Sandulescu, R.5    Arcos, J.6    Kauffmann, J.-M.7


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