ECVAM and pharmaceuticals

Alternatives to Laboratory Animals

Volumn 30, Issue SUPPL. 2, 2002, Pages 221-223

  Vanparys, Philippe ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Alternatives; Animal testing; Drug discovery; Preclinical toxicology

Indexed keywords

ANIMAL MODEL; ANIMAL TESTING ALTERNATIVE; ANIMAL TESTING REDUCTION; ANIMAL TESTING REFINEMENT; ANIMAL WELFARE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG INDUSTRY; DRUG SAFETY; EUROPE; EYE IRRITATION; GENOTOXICITY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT; TOXICITY TESTING;

ANIMALIA;

EID: 0036975222     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290203002s37     Document Type: Conference Paper

References (10)

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8. Hayashi, M., MacGregor, J.T., Gatehouse, D.G., Adler, I-D., Blakey, D.H., Dertinger, S.D., Krishna G., Morita, T., Russo, A. & Sutou, S. (2000). In vivo rodent erythrocyte micronucleus assay: aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring. A report from the International Workshop on Genotoxicity Test Procedures (IWGTP). Environmental and Molecular Mutagenesis 35, 234-252.
9. International Conference on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use (1996). Guidance on Specific Aspects of Regulatory Genotoxicity Tests for Pharmaceuticals (S2A document). Federal Register 61, 18198-18202.
10. Vanparys, P. & Deknudt, G. (1999). The need for positive control animals in routine micronucleus testing. ATLA 27, 370.