-
1
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T., Sirard C., Vormoor J., Murdoch B., Hoang T., Caceres-Cortes J., Minden M., Paterson B., Caligiuri M.A., Dick J.E. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994, 367:645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
2
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D., Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 1997, 3:730-737.
-
(1997)
Nat. Med.
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
3
-
-
3242754448
-
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
-
Hope K.J., Jin L., Dick J.E. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat. Immunol. 2004, 5:738-743.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 738-743
-
-
Hope, K.J.1
Jin, L.2
Dick, J.E.3
-
4
-
-
24344506258
-
Cancer stem cells: lessons from leukemia
-
Wang J.C., Dick J.E. Cancer stem cells: lessons from leukemia. Trends Cell Biol. 2005, 15:494-501.
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 494-501
-
-
Wang, J.C.1
Dick, J.E.2
-
5
-
-
50949090415
-
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells
-
Taussig D.C., Miraki-Moud F., Anjos-Afonso F., Pearce D.J., Allen K., Ridler C., Lillington D., Oakervee H., Cavenagh J., Agrawal S.G., Lister T.A., Gribben J.G., Bonnet D. Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells. Blood 2008, 112:568-575.
-
(2008)
Blood
, vol.112
, pp. 568-575
-
-
Taussig, D.C.1
Miraki-Moud, F.2
Anjos-Afonso, F.3
Pearce, D.J.4
Allen, K.5
Ridler, C.6
Lillington, D.7
Oakervee, H.8
Cavenagh, J.9
Agrawal, S.G.10
Lister, T.A.11
Gribben, J.G.12
Bonnet, D.13
-
6
-
-
77950451485
-
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction
-
Taussig D.C., Vargaftig J., Miraki-Moud F., Griessinger E., Sharrock K., Luke T., Lillington D., Oakervee H., Cavenagh J., Agrawal S.G., Lister T.A., Gribben J.G., Bonnet D. Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction. Blood 2010, 115:1976-1984.
-
(2010)
Blood
, vol.115
, pp. 1976-1984
-
-
Taussig, D.C.1
Vargaftig, J.2
Miraki-Moud, F.3
Griessinger, E.4
Sharrock, K.5
Luke, T.6
Lillington, D.7
Oakervee, H.8
Cavenagh, J.9
Agrawal, S.G.10
Lister, T.A.11
Gribben, J.G.12
Bonnet, D.13
-
7
-
-
80052468964
-
Stem cell gene expression programs influence clinical outcome in human leukemia
-
Eppert K., Takenaka K., Lechman E.R., Waldron L., Nilsson B., van Galen P., Metzeler K.H., Poeppl A., Ling V., Beyene J., Canty A.J., Danska J.S., Bohlander S.K., Buske C., Minden M.D., Golub T.R., Jurisica I., Ebert B.L., Dick J.E. Stem cell gene expression programs influence clinical outcome in human leukemia. Nat. Med. 2011, 17:1086-1093.
-
(2011)
Nat. Med.
, vol.17
, pp. 1086-1093
-
-
Eppert, K.1
Takenaka, K.2
Lechman, E.R.3
Waldron, L.4
Nilsson, B.5
van Galen, P.6
Metzeler, K.H.7
Poeppl, A.8
Ling, V.9
Beyene, J.10
Canty, A.J.11
Danska, J.S.12
Bohlander, S.K.13
Buske, C.14
Minden, M.D.15
Golub, T.R.16
Jurisica, I.17
Ebert, B.L.18
Dick, J.E.19
-
8
-
-
78650950098
-
Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rgammac-deficient mice
-
Sarry J.E., Murphy K., Perry R., Sanchez P.V., Secreto A., Keefer C., Swider C.R., Strzelecki A.C., Cavelier C., Recher C., Mansat-De Mas V., Delabesse E., Danet-Desnoyers G., Carroll M. Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rgammac-deficient mice. J. Clin. Invest. 2011, 121:384-395.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 384-395
-
-
Sarry, J.E.1
Murphy, K.2
Perry, R.3
Sanchez, P.V.4
Secreto, A.5
Keefer, C.6
Swider, C.R.7
Strzelecki, A.C.8
Cavelier, C.9
Recher, C.10
Mansat-De Mas, V.11
Delabesse, E.12
Danet-Desnoyers, G.13
Carroll, M.14
-
9
-
-
70449413732
-
Aldehyde dehydrogenase activity among primary leukemia cells is associated with stem cell features and correlates with adverse clinical outcomes
-
Ran D., Schubert M., Pietsch L., Taubert I., Wuchter P., Eckstein V., Bruckner T., Zoeller M., Ho A.D. Aldehyde dehydrogenase activity among primary leukemia cells is associated with stem cell features and correlates with adverse clinical outcomes. Exp. Hematol. 2009, 37:1423-1434.
-
(2009)
Exp. Hematol.
, vol.37
, pp. 1423-1434
-
-
Ran, D.1
Schubert, M.2
Pietsch, L.3
Taubert, I.4
Wuchter, P.5
Eckstein, V.6
Bruckner, T.7
Zoeller, M.8
Ho, A.D.9
-
10
-
-
78751496866
-
Differential survival of AML subpopulations in NOD/SCID mice
-
e254
-
Schubert M., Herbert N., Taubert I., Ran D., Singh R., Eckstein V., Vitacolonna M., Ho A.D., Zoller M. Differential survival of AML subpopulations in NOD/SCID mice. Exp. Hematol. 2011, 39:250-263. e254.
-
(2011)
Exp. Hematol.
, vol.39
, pp. 250-263
-
-
Schubert, M.1
Herbert, N.2
Taubert, I.3
Ran, D.4
Singh, R.5
Eckstein, V.6
Vitacolonna, M.7
Ho, A.D.8
Zoller, M.9
-
11
-
-
0029958876
-
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
-
Goodell M.A., Brose K., Paradis G., Conner A.S., Mulligan R.C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 1996, 183:1797-1806.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
12
-
-
2542432982
-
ABCG2 - a transporter for all seasons
-
Sarkadi B., Ozvegy-Laczka C., Nemet K., Varadi A. ABCG2 - a transporter for all seasons. FEBS Lett. 2004, 567:116-120.
-
(2004)
FEBS Lett.
, vol.567
, pp. 116-120
-
-
Sarkadi, B.1
Ozvegy-Laczka, C.2
Nemet, K.3
Varadi, A.4
-
13
-
-
0347363610
-
Membrane properties of rat embryonic multipotent neural stem cells
-
Cai J., Cheng A., Luo Y., Lu C., Mattson M.P., Rao M.S., Furukawa K. Membrane properties of rat embryonic multipotent neural stem cells. J. Neurochem. 2004, 88:212-226.
-
(2004)
J. Neurochem.
, vol.88
, pp. 212-226
-
-
Cai, J.1
Cheng, A.2
Luo, Y.3
Lu, C.4
Mattson, M.P.5
Rao, M.S.6
Furukawa, K.7
-
14
-
-
0033529756
-
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
-
Storms R.W., Trujillo A.P., Springer J.B., Shah L., Colvin O.M., Ludeman S.M., Smith C. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc. Natl. Acad. Sci. USA 1999, 96:9118-9123.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9118-9123
-
-
Storms, R.W.1
Trujillo, A.P.2
Springer, J.B.3
Shah, L.4
Colvin, O.M.5
Ludeman, S.M.6
Smith, C.7
-
15
-
-
0035883060
-
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
-
Wulf G.G., Wang R.Y., Kuehnle I., Weidner D., Marini F., Brenner M.K., Andreeff M., Goodell M.A. A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 2001, 98:1166-1173.
-
(2001)
Blood
, vol.98
, pp. 1166-1173
-
-
Wulf, G.G.1
Wang, R.Y.2
Kuehnle, I.3
Weidner, D.4
Marini, F.5
Brenner, M.K.6
Andreeff, M.7
Goodell, M.A.8
-
16
-
-
58049211689
-
Identification of a small subpopulation of candidate leukemia-initiating cells in the side population of patients with acute myeloid leukemia
-
Moshaver B., van Rhenen A., Kelder A., van der Pol M., Terwijn M., Bachas C., Westra A.H., Ossenkoppele G.J., Zweegman S., Schuurhuis G.J. Identification of a small subpopulation of candidate leukemia-initiating cells in the side population of patients with acute myeloid leukemia. Stem Cells 2008, 26:3059-3067.
-
(2008)
Stem Cells
, vol.26
, pp. 3059-3067
-
-
Moshaver, B.1
van Rhenen, A.2
Kelder, A.3
van der Pol, M.4
Terwijn, M.5
Bachas, C.6
Westra, A.H.7
Ossenkoppele, G.J.8
Zweegman, S.9
Schuurhuis, G.J.10
-
17
-
-
84855610965
-
Heterogeneity of leukemia stem cell candidates at diagnosis of acute myeloid leukemia and their clinical significance
-
e151
-
Ran D., Schubert M., Taubert I., Eckstein V., Bellos F., Jauch A., Chen H., Bruckner T., Saffrich R., Wuchter P., Ho A.D. Heterogeneity of leukemia stem cell candidates at diagnosis of acute myeloid leukemia and their clinical significance. Exp. Hematol. 2012, 40:155-165. e151.
-
(2012)
Exp. Hematol.
, vol.40
, pp. 155-165
-
-
Ran, D.1
Schubert, M.2
Taubert, I.3
Eckstein, V.4
Bellos, F.5
Jauch, A.6
Chen, H.7
Bruckner, T.8
Saffrich, R.9
Wuchter, P.10
Ho, A.D.11
-
18
-
-
20344364875
-
Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples
-
Pearce D.J., Taussig D., Simpson C., Allen K., Rohatiner A.Z., Lister T.A., Bonnet D. Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples. Stem Cells 2005, 23:752-760.
-
(2005)
Stem Cells
, vol.23
, pp. 752-760
-
-
Pearce, D.J.1
Taussig, D.2
Simpson, C.3
Allen, K.4
Rohatiner, A.Z.5
Lister, T.A.6
Bonnet, D.7
-
19
-
-
34250732230
-
Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential
-
Cheung A.M., Wan T.S., Leung J.C., Chan L.Y., Huang H., Kwong Y.L., Liang R., Leung A.Y. Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential. Leukemia 2007, 21:1423-1430.
-
(2007)
Leukemia
, vol.21
, pp. 1423-1430
-
-
Cheung, A.M.1
Wan, T.S.2
Leung, J.C.3
Chan, L.Y.4
Huang, H.5
Kwong, Y.L.6
Liang, R.7
Leung, A.Y.8
-
20
-
-
84859854912
-
A clinically relevant population of leukemic CD34+CD38- cells in acute myeloid leukemia
-
Gerber J.M., Smith B.D., Ngwang B., Zhang H., Vala M.S., Morsberger L., Galkin S., Collector M.I., Perkins B., Levis M.J., Griffin C.A., Sharkis S.J., Borowitz M.J., Karp J.E., Jones R.J. A clinically relevant population of leukemic CD34+CD38- cells in acute myeloid leukemia. Blood 2012, 119:3571-3577.
-
(2012)
Blood
, vol.119
, pp. 3571-3577
-
-
Gerber, J.M.1
Smith, B.D.2
Ngwang, B.3
Zhang, H.4
Vala, M.S.5
Morsberger, L.6
Galkin, S.7
Collector, M.I.8
Perkins, B.9
Levis, M.J.10
Griffin, C.A.11
Sharkis, S.J.12
Borowitz, M.J.13
Karp, J.E.14
Jones, R.J.15
-
21
-
-
0030988803
-
Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo
-
Blair A., Hogge D.E., Ailles L.E., Lansdorp P.M., Sutherland H.J. Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo. Blood 1997, 89:3104-3112.
-
(1997)
Blood
, vol.89
, pp. 3104-3112
-
-
Blair, A.1
Hogge, D.E.2
Ailles, L.E.3
Lansdorp, P.M.4
Sutherland, H.J.5
-
22
-
-
67649200331
-
Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells
-
Jin L., Lee E.M., Ramshaw H.S., Busfield S.J., Peoppl A.G., Wilkinson L., Guthridge M.A., Thomas D., Barry E.F., Boyd A., Gearing D.P., Vairo G., Lopez A.F., Dick J.E., Lock R.B. Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells. Cell Stem Cell 2009, 5:31-42.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 31-42
-
-
Jin, L.1
Lee, E.M.2
Ramshaw, H.S.3
Busfield, S.J.4
Peoppl, A.G.5
Wilkinson, L.6
Guthridge, M.A.7
Thomas, D.8
Barry, E.F.9
Boyd, A.10
Gearing, D.P.11
Vairo, G.12
Lopez, A.F.13
Dick, J.E.14
Lock, R.B.15
-
23
-
-
34447646569
-
Aberrant marker expression patterns on the CD34+CD38- stem cell compartment in acute myeloid leukemia allows to distinguish the malignant from the normal stem cell compartment both at diagnosis and in remission
-
van Rhenen A., Moshaver B., Kelder A., Feller N., Nieuwint A.W., Zweegman S., Ossenkoppele G.J., Schuurhuis G.J. Aberrant marker expression patterns on the CD34+CD38- stem cell compartment in acute myeloid leukemia allows to distinguish the malignant from the normal stem cell compartment both at diagnosis and in remission. Leukemia 2007, 21:1700-1707.
-
(2007)
Leukemia
, vol.21
, pp. 1700-1707
-
-
van Rhenen, A.1
Moshaver, B.2
Kelder, A.3
Feller, N.4
Nieuwint, A.W.5
Zweegman, S.6
Ossenkoppele, G.J.7
Schuurhuis, G.J.8
-
24
-
-
34948839959
-
The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells
-
van Rhenen A., van Dongen G.A., Kelder A., Rombouts E.J., Feller N., Moshaver B., Stigter-van Walsum M., Zweegman S., Ossenkoppele G.J., Jan Schuurhuis G. The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells. Blood 2007, 110:2659-2666.
-
(2007)
Blood
, vol.110
, pp. 2659-2666
-
-
van Rhenen, A.1
van Dongen, G.A.2
Kelder, A.3
Rombouts, E.J.4
Feller, N.5
Moshaver, B.6
Stigter-van Walsum, M.7
Zweegman, S.8
Ossenkoppele, G.J.9
Jan Schuurhuis, G.10
-
25
-
-
34547415968
-
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia
-
Hosen N., Park C.Y., Tatsumi N., Oji Y., Sugiyama H., Gramatzki M., Krensky A.M., Weissman I.L. CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proc. Natl. Acad. Sci. USA 2007, 104:11008-11013.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 11008-11013
-
-
Hosen, N.1
Park, C.Y.2
Tatsumi, N.3
Oji, Y.4
Sugiyama, H.5
Gramatzki, M.6
Krensky, A.M.7
Weissman, I.L.8
-
26
-
-
67650632683
-
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
-
Majeti R., Chao M.P., Alizadeh A.A., Pang W.W., Jaiswal S., Gibbs K.D., van Rooijen N., Weissman I.L. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell 2009, 138:286-299.
-
(2009)
Cell
, vol.138
, pp. 286-299
-
-
Majeti, R.1
Chao, M.P.2
Alizadeh, A.A.3
Pang, W.W.4
Jaiswal, S.5
Gibbs, K.D.6
van Rooijen, N.7
Weissman, I.L.8
-
27
-
-
78649686241
-
TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells
-
Kikushige Y., Shima T., Takayanagi S., Urata S., Miyamoto T., Iwasaki H., Takenaka K., Teshima T., Tanaka T., Inagaki Y., Akashi K. TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells. Cell Stem Cell 2010, 7:708-717.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 708-717
-
-
Kikushige, Y.1
Shima, T.2
Takayanagi, S.3
Urata, S.4
Miyamoto, T.5
Iwasaki, H.6
Takenaka, K.7
Teshima, T.8
Tanaka, T.9
Inagaki, Y.10
Akashi, K.11
-
28
-
-
67650646082
-
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis
-
Jaiswal S., Jamieson C.H., Pang W.W., Park C.Y., Chao M.P., Majeti R., Traver D., van Rooijen N., Weissman I.L. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 2009, 138:271-285.
-
(2009)
Cell
, vol.138
, pp. 271-285
-
-
Jaiswal, S.1
Jamieson, C.H.2
Pang, W.W.3
Park, C.Y.4
Chao, M.P.5
Majeti, R.6
Traver, D.7
van Rooijen, N.8
Weissman, I.L.9
-
29
-
-
84862012956
-
The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse
-
Bachas C., Schuurhuis G.J., Assaraf Y.G., Kwidama Z.J., Kelder A., Wouters F., Snel A.N., Kaspers G.J., Cloos J. The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse. Leukemia 2012.
-
(2012)
Leukemia
-
-
Bachas, C.1
Schuurhuis, G.J.2
Assaraf, Y.G.3
Kwidama, Z.J.4
Kelder, A.5
Wouters, F.6
Snel, A.N.7
Kaspers, G.J.8
Cloos, J.9
-
30
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K., Lutz C., van Delft F.W., Bateman C.M., Guo Y., Colman S.M., Kempski H., Moorman A.V., Titley I., Swansbury J., Kearney L., Enver T., Greaves M. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011, 469:356-361.
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
van Delft, F.W.3
Bateman, C.M.4
Guo, Y.5
Colman, S.M.6
Kempski, H.7
Moorman, A.V.8
Titley, I.9
Swansbury, J.10
Kearney, L.11
Enver, T.12
Greaves, M.13
-
31
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F., Mullighan C.G., Wang J.C., Poeppl A., Doulatov S., Phillips L.A., Ma J., Minden M.D., Downing J.R., Dick J.E. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 2011, 469:362-367.
-
(2011)
Nature
, vol.469
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.3
Poeppl, A.4
Doulatov, S.5
Phillips, L.A.6
Ma, J.7
Minden, M.D.8
Downing, J.R.9
Dick, J.E.10
-
32
-
-
51349126920
-
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing
-
Campbell P.J., Pleasance E.D., Stephens P.J., Dicks E., Rance R., Goodhead I., Follows G.A., Green A.R., Futreal P.A., Stratton M.R. Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing. Proc Natl Acad Sci USA 2008, 105:13081-13086.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13081-13086
-
-
Campbell, P.J.1
Pleasance, E.D.2
Stephens, P.J.3
Dicks, E.4
Rance, R.5
Goodhead, I.6
Follows, G.A.7
Green, A.R.8
Futreal, P.A.9
Stratton, M.R.10
-
33
-
-
57149118627
-
Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia
-
Mullighan C.G., Phillips L.A., Su X., Ma J., Miller C.B., Shurtleff S.A., Downing J.R. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science 2008, 322:1377-1380.
-
(2008)
Science
, vol.322
, pp. 1377-1380
-
-
Mullighan, C.G.1
Phillips, L.A.2
Su, X.3
Ma, J.4
Miller, C.B.5
Shurtleff, S.A.6
Downing, J.R.7
-
34
-
-
31544436322
-
AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML
-
Pearce D.J., Taussig D., Zibara K., Smith L.L., Ridler C.M., Preudhomme C., Young B.D., Rohatiner A.Z., Lister T.A., Bonnet D. AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML. Blood 2006, 107:1166-1173.
-
(2006)
Blood
, vol.107
, pp. 1166-1173
-
-
Pearce, D.J.1
Taussig, D.2
Zibara, K.3
Smith, L.L.4
Ridler, C.M.5
Preudhomme, C.6
Young, B.D.7
Rohatiner, A.Z.8
Lister, T.A.9
Bonnet, D.10
-
35
-
-
25144433295
-
High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival
-
van Rhenen A., Feller N., Kelder A., Westra A.H., Rombouts E., Zweegman S., van der Pol M.A., Waisfisz Q., Ossenkoppele G.J., Schuurhuis G.J. High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival. Clin. Cancer Res. 2005, 11:6520-6527.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 6520-6527
-
-
van Rhenen, A.1
Feller, N.2
Kelder, A.3
Westra, A.H.4
Rombouts, E.5
Zweegman, S.6
van der Pol, M.A.7
Waisfisz, Q.8
Ossenkoppele, G.J.9
Schuurhuis, G.J.10
-
36
-
-
0242268524
-
Osteoblastic cells regulate the haematopoietic stem cell niche
-
Calvi L.M., Adams G.B., Weibrecht K.W., Weber J.M., Olson D.P., Knight M.C., Martin R.P., Schipani E., Divieti P., Bringhurst F.R., Milner L.A., Kronenberg H.M., Scadden D.T. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003, 425:841-846.
-
(2003)
Nature
, vol.425
, pp. 841-846
-
-
Calvi, L.M.1
Adams, G.B.2
Weibrecht, K.W.3
Weber, J.M.4
Olson, D.P.5
Knight, M.C.6
Martin, R.P.7
Schipani, E.8
Divieti, P.9
Bringhurst, F.R.10
Milner, L.A.11
Kronenberg, H.M.12
Scadden, D.T.13
-
37
-
-
84868542509
-
The vascular niche: home for normal and malignant hematopoietic stem cells
-
Doan P.L., Chute J.P. The vascular niche: home for normal and malignant hematopoietic stem cells. Leukemia 2011.
-
(2011)
Leukemia
-
-
Doan, P.L.1
Chute, J.P.2
-
38
-
-
79959810834
-
Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells
-
Nagasawa T., Omatsu Y., Sugiyama T. Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells. Trends Immunol. 2011, 32:315-320.
-
(2011)
Trends Immunol.
, vol.32
, pp. 315-320
-
-
Nagasawa, T.1
Omatsu, Y.2
Sugiyama, T.3
-
39
-
-
54949103952
-
Aging of hematopoietic stem cells is regulated by the stem cell niche
-
Wagner W., Horn P., Bork S., Ho A.D. Aging of hematopoietic stem cells is regulated by the stem cell niche. Exp. Gerontol. 2008, 43:974-980.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 974-980
-
-
Wagner, W.1
Horn, P.2
Bork, S.3
Ho, A.D.4
-
40
-
-
46949087282
-
Adhesion of human hematopoietic progenitor cells to mesenchymal stromal cells involves CD44
-
Wagner W., Wein F., Roderburg C., Saffrich R., Diehlmann A., Eckstein V., Ho A.D. Adhesion of human hematopoietic progenitor cells to mesenchymal stromal cells involves CD44. Cells Tissues Organs 2008, 188:160-169.
-
(2008)
Cells Tissues Organs
, vol.188
, pp. 160-169
-
-
Wagner, W.1
Wein, F.2
Roderburg, C.3
Saffrich, R.4
Diehlmann, A.5
Eckstein, V.6
Ho, A.D.7
-
41
-
-
33846444324
-
Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell-cell interaction
-
Wagner W., Wein F., Roderburg C., Saffrich R., Faber A., Krause U., Schubert M., Benes V., Eckstein V., Maul H., Ho A.D. Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell-cell interaction. Exp. Hematol. 2007, 35:314-325.
-
(2007)
Exp. Hematol.
, vol.35
, pp. 314-325
-
-
Wagner, W.1
Wein, F.2
Roderburg, C.3
Saffrich, R.4
Faber, A.5
Krause, U.6
Schubert, M.7
Benes, V.8
Eckstein, V.9
Maul, H.10
Ho, A.D.11
-
42
-
-
77951962617
-
Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells
-
Walenda T., Bork S., Horn P., Wein F., Saffrich R., Diehlmann A., Eckstein V., Ho A.D., Wagner W. Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells. J. Cell Mol. Med. 2010, 14:337-350.
-
(2010)
J. Cell Mol. Med.
, vol.14
, pp. 337-350
-
-
Walenda, T.1
Bork, S.2
Horn, P.3
Wein, F.4
Saffrich, R.5
Diehlmann, A.6
Eckstein, V.7
Ho, A.D.8
Wagner, W.9
-
43
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
Jin L., Hope K.J., Zhai Q., Smadja-Joffe F., Dick J.E. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 2006, 12:1167-1174.
-
(2006)
Nat. Med.
, vol.12
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
44
-
-
33846241600
-
CXCR4 is a prognostic marker in acute myelogenous leukemia
-
Spoo A.C., Lubbert M., Wierda W.G., Burger J.A. CXCR4 is a prognostic marker in acute myelogenous leukemia. Blood 2007, 109:786-791.
-
(2007)
Blood
, vol.109
, pp. 786-791
-
-
Spoo, A.C.1
Lubbert, M.2
Wierda, W.G.3
Burger, J.A.4
-
45
-
-
33845445939
-
Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
-
Sugiyama T., Kohara H., Noda M., Nagasawa T. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 2006, 25:977-988.
-
(2006)
Immunity
, vol.25
, pp. 977-988
-
-
Sugiyama, T.1
Kohara, H.2
Noda, M.3
Nagasawa, T.4
-
46
-
-
76749142865
-
N-cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells
-
Wein F., Pietsch L., Saffrich R., Wuchter P., Walenda T., Bork S., Horn P., Diehlmann A., Eckstein V., Ho A.D., Wagner W. N-cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells. Stem Cell Res. 2010, 4:129-139.
-
(2010)
Stem Cell Res.
, vol.4
, pp. 129-139
-
-
Wein, F.1
Pietsch, L.2
Saffrich, R.3
Wuchter, P.4
Walenda, T.5
Bork, S.6
Horn, P.7
Diehlmann, A.8
Eckstein, V.9
Ho, A.D.10
Wagner, W.11
-
47
-
-
77953090345
-
CXCL12 (SDF-1)/CXCR4 pathway in cancer
-
Teicher B.A., Fricker S.P. CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin. Cancer Res. 2010, 16:2927-2931.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2927-2931
-
-
Teicher, B.A.1
Fricker, S.P.2
-
48
-
-
67650410440
-
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
-
Nervi B., Ramirez P., Rettig M.P., Uy G.L., Holt M.S., Ritchey J.K., Prior J.L., Piwnica-Worms D., Bridger G., Ley T.J., DiPersio J.F. Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. Blood 2009, 113:6206-6214.
-
(2009)
Blood
, vol.113
, pp. 6206-6214
-
-
Nervi, B.1
Ramirez, P.2
Rettig, M.P.3
Uy, G.L.4
Holt, M.S.5
Ritchey, J.K.6
Prior, J.L.7
Piwnica-Worms, D.8
Bridger, G.9
Ley, T.J.10
DiPersio, J.F.11
-
49
-
-
0141461414
-
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
-
Matsunaga T., Takemoto N., Sato T., Takimoto R., Tanaka I., Fujimi A., Akiyama T., Kuroda H., Kawano Y., Kobune M., Kato J., Hirayama Y., Sakamaki S., Kohda K., Miyake K., Niitsu Y. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia. Nat. Med. 2003, 9:1158-1165.
-
(2003)
Nat. Med.
, vol.9
, pp. 1158-1165
-
-
Matsunaga, T.1
Takemoto, N.2
Sato, T.3
Takimoto, R.4
Tanaka, I.5
Fujimi, A.6
Akiyama, T.7
Kuroda, H.8
Kawano, Y.9
Kobune, M.10
Kato, J.11
Hirayama, Y.12
Sakamaki, S.13
Kohda, K.14
Miyake, K.15
Niitsu, Y.16
-
50
-
-
70349348954
-
BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells
-
Ramirez P., Rettig M.P., Uy G.L., Deych E., Holt M.S., Ritchey J.K., DiPersio J.F. BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells. Blood 2009, 114:1340-1343.
-
(2009)
Blood
, vol.114
, pp. 1340-1343
-
-
Ramirez, P.1
Rettig, M.P.2
Uy, G.L.3
Deych, E.4
Holt, M.S.5
Ritchey, J.K.6
DiPersio, J.F.7
-
51
-
-
3042775143
-
The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells
-
Gadhoum Z., Delaunay J., Maquarre E., Durand L., Lancereaux V., Qi J., Robert-Lezenes J., Chomienne C., Smadja-Joffe F. The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells. Leuk. Lymphoma 2004, 45:1501-1510.
-
(2004)
Leuk. Lymphoma
, vol.45
, pp. 1501-1510
-
-
Gadhoum, Z.1
Delaunay, J.2
Maquarre, E.3
Durand, L.4
Lancereaux, V.5
Qi, J.6
Robert-Lezenes, J.7
Chomienne, C.8
Smadja-Joffe, F.9
-
52
-
-
0025992197
-
Most primitive hematopoietic stem cells are stimulated to cycle rapidly after treatment with 5-fluorouracil
-
Harrison D.E., Lerner C.P. Most primitive hematopoietic stem cells are stimulated to cycle rapidly after treatment with 5-fluorouracil. Blood 1991, 78:1237-1240.
-
(1991)
Blood
, vol.78
, pp. 1237-1240
-
-
Harrison, D.E.1
Lerner, C.P.2
-
53
-
-
0025138652
-
5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation
-
Lerner C., Harrison D.E. 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp. Hematol. 1990, 18:114-118.
-
(1990)
Exp. Hematol.
, vol.18
, pp. 114-118
-
-
Lerner, C.1
Harrison, D.E.2
-
54
-
-
66149115277
-
IFNalpha activates dormant haematopoietic stem cells in vivo
-
Essers M.A., Offner S., Blanco-Bose W.E., Waibler Z., Kalinke U., Duchosal M.A., Trumpp A. IFNalpha activates dormant haematopoietic stem cells in vivo. Nature 2009, 458:904-908.
-
(2009)
Nature
, vol.458
, pp. 904-908
-
-
Essers, M.A.1
Offner, S.2
Blanco-Bose, W.E.3
Waibler, Z.4
Kalinke, U.5
Duchosal, M.A.6
Trumpp, A.7
-
55
-
-
77749317560
-
Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML
-
Saito Y., Uchida N., Tanaka S., Suzuki N., Tomizawa-Murasawa M., Sone A., Najima Y., Takagi S., Aoki Y., Wake A., Taniguchi S., Shultz L.D., Ishikawa F. Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML. Nat. Biotechnol. 2010, 28:275-280.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 275-280
-
-
Saito, Y.1
Uchida, N.2
Tanaka, S.3
Suzuki, N.4
Tomizawa-Murasawa, M.5
Sone, A.6
Najima, Y.7
Takagi, S.8
Aoki, Y.9
Wake, A.10
Taniguchi, S.11
Shultz, L.D.12
Ishikawa, F.13
-
56
-
-
0042967809
-
Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
-
Lowenberg B., van Putten W., Theobald M., Gmur J., Verdonck L., Sonneveld P., Fey M., Schouten H., de Greef G., Ferrant A., Kovacsovics T., Gratwohl A., Daenen S., Huijgens P., Boogaerts M. Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia. N. Engl. J. Med. 2003, 349:743-752.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 743-752
-
-
Lowenberg, B.1
van Putten, W.2
Theobald, M.3
Gmur, J.4
Verdonck, L.5
Sonneveld, P.6
Fey, M.7
Schouten, H.8
de Greef, G.9
Ferrant, A.10
Kovacsovics, T.11
Gratwohl, A.12
Daenen, S.13
Huijgens, P.14
Boogaerts, M.15
-
57
-
-
0034662606
-
Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities
-
Costello R.T., Mallet F., Gaugler B., Sainty D., Arnoulet C., Gastaut J.A., Olive D. Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities. Cancer Res. 2000, 60:4403-4411.
-
(2000)
Cancer Res.
, vol.60
, pp. 4403-4411
-
-
Costello, R.T.1
Mallet, F.2
Gaugler, B.3
Sainty, D.4
Arnoulet, C.5
Gastaut, J.A.6
Olive, D.7
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