Protective effects of urinary trypsin inhibitor on vascular permeability following subarachnoid hemorrhage in a rat model

CNS Neuroscience and Therapeutics

Volumn 19, Issue 9, 2013, Pages 659-666

  Zhou, Ning ^a   Xu, Ting ^b   Bai, Ying ^a   Prativa, Sherchan ^c   Xu, Jia Zhou ^b,d   Li, Kai ^e   Han, Hong Bin ^e   Yan, Jun Hao ^b  

^a Beijing Jishuitan Hospital   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ZUNYI MEDICAL UNIVERSITY   (China)

^e PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

Magnetic resonance imaging; Rat; Subarachnoid hemorrhage; Urinary trypsin inhibitor; Vascular permeability

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MALONALDEHYDE; MYELOPEROXIDASE; PROTECTIVE AGENT; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BRAIN EDEMA; BRAIN WATER; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RANDOMIZED CONTROLLED TRIAL; RAT; SPRAGUE DAWLEY RAT; SUBARACHNOID HEMORRHAGE; WATER CONTENT; WESTERN BLOTTING;

MAGNETIC RESONANCE IMAGING; RAT; SUBARACHNOID HEMORRHAGE; URINARY TRYPSIN INHIBITOR; VASCULAR PERMEABILITY;

ANIMALS; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAGNETIC RESONANCE IMAGING; MALE; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; SUBARACHNOID HEMORRHAGE; TRYPSIN INHIBITORS;

EID: 84882823051     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12122     Document Type: Article

References (37)

1. Claassen J, Carhuapoma JR, Kreiter KT, Du EY, Connolly ES, Mayer SA. Global cerebral edema after subarachnoid hemorrhage: Frequency, predictors, and impact on outcome. Stroke 2002;33:1225-1232.
2. Yan J, Li L, Khatibi NH, et al. Blood-brain barrier disruption following subarchnoid hemorrhage may be facilitated through PUMA induction of endothelial cell apoptosis from the endoplasmic reticulum. Exp Neurol 2011;230:240-247.
3. Altay O, Suzuki H, Hasegawa Y, et al. Isoflurane attenuates blood-brain barrier disruption in ipsilateral hemisphere after subarachnoid hemorrhage in mice. Stroke 2012;43:2513-2516.
4. Sercombe R, Dinh YR, Gomis P. Cerebrovascular inflammation following subarachnoid hemorrhage. Jpn J Pharmacol 2002;88:227-249.
5. Park S, Yamaguchi M, Zhou C, Calvert JW, Tang J, Zhang JH. Neurovascular protection reduces early brain injury after subarachnoid hemorrhage. Stroke 2004;35:2412-2417.
6. Yan J, Chen C, Hu Q, et al. The role of p53 in brain edema after 24 h of experimental subarachnoid hemorrhage in a rat model. Exp Neurol 2008;214:37-46.
7. Simard JM, Geng Z, Woo SK, et al. Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage. J Cereb Blood Flow Metab 2009;29:317-330.
8. Yamaguchi Y, Ohshiro H, Nagao Y, et al. Urinary trypsin inhibitor reduces C-X-C chemokine production in rat liver ischemia/reperfusion. J Surg Res 2000;94:107-115.
9. Zhou C, Yamaguchi M, Kusaka G, Schonholz C, Nanda A, Zhang JH. Caspase inhibitors prevent endothelial apoptosis and cerebral vasospasm in dog model of experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab 2004;24:419-431.
10. Özsavcí D, Erşahin M, Şener A, et al. The novel function of nesfatin-1 as an anti-inflammatory and antiapoptotic peptide in subarachnoid hemorrhage-induced oxidative brain damage in rats. Neurosurgery 2011;68:1699-1708.
11. Liu X, Sun J. Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-kappaB pathways. Biomaterials 2010;31:8198-8209.
12. Zhang Y, Fong CC, Wong MS, et al. Molecular mechanisms of survival and apoptosis in RAW 264.7 macrophages under oxidative stress. Apoptosis 2005;10:545-556.
13. Friedrich V, Flores R, Muller A, Bi W, Peerschke EI, Sehba FA. Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage. J Neuroinflammation 2011;8:103.
14. Kobayashi H, Gotoh J, Fujie M, Terao T. Characterization of the cellular binding site for the urinary trypsin inhibitor. J Biol Chem 1994;269:20642-20647.
15. Endo S, Inada K, Yamashita H, et al. The inhibitory actions of protease inhibitors on the production of polymorphonuclear leukocyte elastase and interleukin 8. Res Commun Chem Pathol Pharmacol 1993;82:27-34.
16. Nakatani K, Takeshita S, Tsujimoto H, Kawamura Y, Sekine I. Inhibitory effect of serine protease inhibitors on neutrophil-mediated endothelial cell injury. J Leukoc Biol 2001;69:241-247.
17. Li XK, Suzuki H, Kimura T, Kawabe A, Uno T, Harada Y. Ulinastatin, a protease inhibitor, attenuates intestinal ischemia/reperfusion injury. Transplant Proc 1994;26:2423-2425.
18. Nakahama H, Obata K, Sugita M. Ulinastatin ameliorates acute ischemic renal injury in rats. Ren Fail 1996;18:893-898.
19. Aihara T, Shiraishi M, Hiroyasu S, et al. Ulinastatin, a protease inhibitor, attenuates hepatic ischemia/reperfusion injury by downregulating TNF-alpha in the liver. Transplant Proc 1998;30:3732-3734.
20. Duris K, Manaenko A, Suzuki H, Rolland W, Tang J, Zhang JH. Sampling of CSF via the cisterna magna and blood collection via the heart affects brain water content in a rat SAH model. Transl Stroke Res 2011;2:232-237.
21. Sugawara T, Ayer R, Jadhav V, Zhang JH. A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model. J Neurosci Methods 2008;167:327-334.
22. Garcia JH, Wagner S, Liu KF, Hu XJ. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 1995;26:627-634.
23. Han H, Xia Z, Chen H, Hou C, Li W. Simple diffusion delivery via brain interstitial route for the treatment of cerebral ischemia. Sci China Life Sci 2011;54:235-239.
24. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. London: Academic Press, 1986.
25. Ma Q, Manaenko A, Khatibi NH, Chen W, Zhang JH, Tang J. Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice. J Cereb Blood Flow Metab 2011;31:881-893.
26. Ma Q, Huang B, Khatibi N, et al. PDGFR-α inhibition preserves blood-brain barrier after intracerebral hemorrhage. Ann Neurol 2011;70:920-931.
27. Sherchan P, Lekic T, Hidenori S, et al. Minocycline improves functional outcomes, memory deficits and histopathology after endovascular perforation-induced subarachnoid hemorrhage in rats. J Neurotrauma 2011;28:2503-2512.
28. Yan JH, Khatibi NH, Han HB, et al. p53-induced uncoupling expression of aquaporin-4 and inwardly rectifying K+ 4.1 channels in cytotoxic edema after subarachnoid hemorrhage. CNS Neurosci Ther 2012;18:334-342.
29. Yu JR, Yan S, Liu XS, et al. Attenuation of graft ischemia-reperfusion injury by urinary trypsin inhibitor in mouse intestinal transplantation. World J Gastroenterol 2005;11:1605-1609.
30. Shin IW, Jang IS, Lee SM, et al. Myocardial protective effect by ulinastatin via an anti-inflammatory response after regional ischemia/reperfusion injury in an in vivo rat heart model. Korean J Anesthesiol 2011;61:499-505.
31. Chou SH, Feske SK, Simmons SL, et al. Elevated peripheral neutrophils and matrix metalloproteinase 9 as biomarkers of functional outcome following subarachnoid hemorrhage. Transl Stroke Res 2011;2:600-607.
32. Owen CA, Campbell EJ. The cell biology of leukocyte-mediated proteolysis. J Leukoc Biol 1999;65:137-150.
33. Davies C, Tournier C. Exploring the function of the JNK (c-Jun N-terminal kinase) signaling pathway in physiological and pathological processes to design novel therapeutic strategies. Biochem Soc Trans 2012;40:85-89.
34. Wang L, Li JY, Zhang XZ, et al. Involvement of p38MAPK/NF-κB signaling pathways in osteoblasts differentiation in response to mechanical stretch. Ann Biomed Eng 2012;40:1884-1894.
35. Sironi L, Banfi C, Brioschi M, et al. Activation of NF-κB and ERK1/2 after permanent focal ischemia is abolished by simvastatin treatment. Neurobiol Dis 2006;22:445-451.
36. Zhang HL, Gu ZL, Savitz SI, Han F, Fukunaga K, Qin ZH. Neuroprotective effects of prostaglandinA (1) in rat models of permanent focal cerebral ischemia are associated with nuclear factor-kappaB inhibition and peroxisome proliferator-activated receptor-gamma up-regulation. J Neurosci Res 2008;86:1132-1141.
37. Kim MS, Kwon JY, Kang NJ, Lee KW, Lee HJ. Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling. Ann N Y Acad Sci 2009;1171:479-483.