Blood-brain barrier disruption following subarchnoid hemorrhage may be faciliated through PUMA induction of endothelial cell apoptosis from the endoplasmic reticulum

Experimental Neurology

Volumn 230, Issue 2, 2011, Pages 240-247

  Yan, Junhao ^a,b   Li, Li ^a   Khatibi, Nikan H ^b   Yang, Lei ^a   Wang, Ke ^a   Zhang, Weiguang ^a   Martin, Robert D ^b   Han, Jingyan ^a   Zhang, John ^b   Zhou, Changman ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Blood brain barrier; Endoplasmic reticulum; P53 upregulated modulator of apoptosis; Subarachnoid hemorrhage

Indexed keywords

DYNAMIN; GLUCOSE REGULATED PROTEIN 78; PROTEIN BAK; PROTEIN BAX; PROTEIN DRP1; PUMA PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER DISRUPTION; BRAIN EDEMA; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HIPPOCAMPUS; MALE; MEMBRANE DAMAGE; MICROVASCULAR ENDOTHELIAL CELL; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SUBARACHNOID HEMORRHAGE;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; BRAIN EDEMA; ENDOPLASMIC RETICULUM; ENDOTHELIAL CELLS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; PERMEABILITY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE;

EID: 79958741053     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.04.022     Document Type: Article

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