Urinary trypsin inhibitor reduces C-X-C chemokine production in rat liver ischemia/reperfusion

Journal of Surgical Research

Volumn 94, Issue 2, 2000, Pages 107-115

  Yamaguchi, Yasuo ^a   Ohshiro, Hajime ^a   Nagao, Yuji ^b   Odawara, Kiichiro ^b   Okabe, Kazutoshi ^a   Hidaka, Hideki ^a   Ishihara, Kohjiroh ^a   Uchino, Shinichiro ^a   Furuhashi, Takashi ^a   Shinwa, Yamada ^c   Mori, Katsutaka ^a   Ogawa, Michio ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b MOCHIDA PHARMACEUTICAL CO   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Cytokine induced neutrophil chemoattractant; Ischemia reperfusion injury; Kupffer cells; Neutrophil elastase

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA CHEMOKINE; ASPARTATE AMINOTRANSFERASE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; LACTATE DEHYDROGENASE; LEUKOCYTE ELASTASE; LIVER ENZYME; PROTEINASE; PROTEINASE INHIBITOR; SIVELESTAT; ULINASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; KUPFFER CELL; LIVER ISCHEMIA; MALE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NORTHERN BLOTTING; PERITONEUM MACROPHAGE; PORTAL VEIN OBSTRUCTION; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

EID: 0033664331     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2000.5999     Document Type: Article

References (64)

1. Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo
2. Liver injury is a reversible neutrophil-mediated event following gut ischemia
3. The neutrophil chemoattractant produced by the rat kidney epithelial cell line NRK-52E is a protein related to the KC/gro protein
4. Effect of rat CINC/gro a member of the interleukin-8 family on leukocytes in microcirculation of the rat mesentery
5. Purification and characterization of cytokine-induced neutrophil chemoattractant produced by epithelial cell line of normal rat kidney (NRK-52E cell)
6. Kupffer cell production of cytokine-induced neutrophil chemoattractant (CINC) following ischemia/reperfusion injury in rats
7. Effect of protease inhibitor on ischemia/reperfusion injury of the rat liver
8. Protective effects of ulinastatin against ischemia-reperfusion injury
9. Neutrophil elastase inhibitor reduces neutrophil chemoattractant production after ischemia-reperfusion in rat liver
10. Novel factor Xa and plasma kallikrein inhibitory-activities of the second Kunitz-type inhibitory domain of urinary trypsin inhibitor
11. Inhibition of tumor cell invasion through matrigel by a peptide derived from the domain II region in urinary trypsin inhibition
12. Effects of a urinary trypsin inhibitor on acute circulatory insufficiency after surgical operation
13. Changes in the levels of rat interleukin 8/CINC and gelatinase in the exudate of carrageenan-induced inflammation in rats
14. Cytochemical identification of monocytes and granulocytes
15. High yield preparation of isolated rat liver parenchymal cells. A biochemical and fine structure study
16. Preparation of isolated rat liver cells
17. A comparative endothelin- and platelet-activating-factor-mediated signal transduction and prostaglandin synthesis in rat Kupffer cells
18. The synthesis and analytical use of a highly sensitive and convenient substrate of elastase
19. ONO- 5046 a novel inhibitor of human neutrophil elastase
20. Nafamostat mesilate a broad spectrum protease inhibitor modulates platelet neutrophil and contact activation in simulated extracorporeal circulation
21. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
22. Kinetics of interleukin-1 secretion by murine macrophages recovered from the peritoneal cavity after surgery
23. Isolation of leukocytes granulocytes and macrophages
24. Establishment of a new perchloric acid treatment method to allow determination of the total endotoxin content in human plasma by the limulus test and clinical application
25. Inhibition of AP-1 and NF-kappaB by manganese-containing superoxide dismutase in human breast cancer cells
26. Inhibition of TNF-α-induced NF-kappaB activation and IL-8 release in A549 cells with the proteasome inhibitor MG- 132
27. Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants
28. Yersinia enterocolitica impairs activation of transcription factor NF-kappaB: Involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor α production
29. A monoclonal antibody to the adherence-promoting leukocyte glycoprotein CD 18 reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits
30. Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases
31. Neutrophil elastase: A determinant of endothelial damage and reperfusion injury after liver transplantation?
32. Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase
33. Reperfusion-induced leukocyte infiltration: Role of elastase
34. Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin- 8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor
35. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin- 8 gene expression in a human bronchial epithelial cell line
36. Protease inhibitors of human plasma. Antithrombin-III. 'The heparin-antithrombin system
37. Synthesis and release of interleukin 1 by reoxygenated human mononuclear phagocytes
38. Inactivation of human antithrombin by neutrophil elastase. Kinetics of the heparin-dependent reaction
39. Interaction of heparin cofactor II with neutrophil elastase and cathepsin G
40. Protein S degradation in vitro by neutrophil elastase
41. D-dimers are degraded by human neutrophil elastase
42. Interactions of neutrophils and coagulation proteins
43. Inositol triphosphate a novel second messenger in cellular signal transduction
44. Mechanisms of action of calcium mobilizing agonists: Some variations on young theme
45. Cytokine-induced neutrophil chemoattractant mediates neutrophilic alveolitis in rats: Association with nuclear factor kappa B activation
46. 2+ and reactive oxygen intermediates as messengers
47. Intracellular calcium affects neutrophil chemoattractant expression by macrophages in rats with cerulein-induced pancreatitis
48. 2+ in HL 60 cells and HUVEC cells
49. 2+ in human neutrophils and HUVEC cells
50. Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/gro a member of the interleukin-8 family through impairment of NF-kB activation
51. RelB regulation of chemokine expression modulates local inflammation
52. Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa B in rat lung: Inhibition by corticosteroids
53. Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat
54. Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes
55. Pyrrolidine dithiocarbamate prevents I-kappaB degradation and reduces microvascular injury induced by lipopolysaccharide in multiple organs
56. Transient nuclear factor kappaB (NF-kappaB) activation stimulated by interleukin-1β may be partly dependent on proteasome activity but not phosphorylation and ubiquitination of the IkappaBα molecule in C6 glioma cells. Regulation of NF-kappaB linked to chemokine production
57. The mechanism of hepatic cellular injury in sepsis: An in vitro study of the implications of cytokines and neutrophils in its pathogenesis
58. Effects of ulinastatin on polymorphonuclear leukocyte elastase and interleukin 6 levels after hepatectomy
59. A human urinary protease inhibitor (ulinastatin) inhibits neutrophil extracellular release of elastase during cardiopulmonary bypass
60. Inhibition of neutrophil elastase-induced interleukin- 8 gene expression by urinary trypsin inhibitor in human bronchial epithelial cells
61. Effect of urinary trypsin inhibitor on pancreatic cellular and lysosomal fragility in cerulein-induced acute pancreatitis in rats
62. Human urinary trypsin inhibitor urinastatin prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat
63. Human neutrophil elastase degrades inter-α-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins