-
1
-
-
0037032835
-
The protein kinase complement of the human genome
-
G. Manning, D. B. Whyte, R. Martinez, T. Hunter, S. Sudarsanam, The protein kinase complement of the human genome. Science 298, 1912-1934 (2002).
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
2
-
-
0036527429
-
Protein kinases - The major drug targets of the twenty-first century?
-
P. Cohen, Protein kinases - the major drug targets of the twenty-first century? Nat. Rev. Drug Discov. 1, 309-315 (2002).
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 309-315
-
-
Cohen, P.1
-
3
-
-
0028938721
-
Catalytic specificity of protein-tyrosine kinases is critical for selective signaling
-
Z. Songyang, K. L. Carraway, M. Eck, S. C. Harrison, R. A. Feldman, M. Mohammadi, J. Schlessinger, S. R. Hubbard, D. P. Smith, C. Eng, M. J. Lorenzo, B. A. J. Ponder, B. J. Mayer, L. C. Cantley, Catalytic specificity of protein-tyrosine kinases is critical for selective signaling. Nature 373, 536-539 (1995).
-
(1995)
Nature
, vol.373
, pp. 536-539
-
-
Songyang, Z.1
Carraway, K.L.2
Eck, M.3
Harrison, S.C.4
Feldman, R.A.5
Mohammadi, M.6
Schlessinger, J.7
Hubbard, S.R.8
Smith, D.P.9
Eng, C.10
Lorenzo, M.J.11
Ponder, B.A.J.12
Mayer, B.J.13
Cantley, L.C.14
-
4
-
-
0000028057
-
Substrate specificity of the cyclic AMP-dependent protein kinase
-
B. E. Kemp, D. B. Bylund, T. S. Huang, E. G. Krebs, Substrate specificity of the cyclic AMP-dependent protein kinase. Proc. Natl. Acad. Sci. U.S.A. 72, 3448-3452 (1975).
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 3448-3452
-
-
Kemp, B.E.1
Bylund, D.B.2
Huang, T.S.3
Krebs, E.G.4
-
5
-
-
0017078844
-
The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver
-
O. Zetterqvist, U. Ragnarsson, E. Humble, L. Berglund, L. Engstrom, The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver. Biochem.Biophys.Res. Commun. 70, 696-703 (1976).
-
(1976)
Biochem. Biophys. Res. Commun.
, vol.70
, pp. 696-703
-
-
Zetterqvist, O.1
Ragnarsson, U.2
Humble, E.3
Berglund, L.4
Engstrom, L.5
-
6
-
-
0017638132
-
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase
-
B. E. Kemp, D. J. Graves, E. Benjamini, E. G. Krebs, Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase. J. Biol. Chem. 252, 4888-4894 (1977).
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 4888-4894
-
-
Kemp, B.E.1
Graves, D.J.2
Benjamini, E.3
Krebs, E.G.4
-
7
-
-
0036629182
-
Towards quantitative assays with peptide chips: A surface engineering approach
-
B. T. Houseman, M. Mrksich, Towards quantitative assays with peptide chips: A surface engineering approach. Trends Biotechnol. 20, 279-281 (2002).
-
(2002)
Trends Biotechnol.
, vol.20
, pp. 279-281
-
-
Houseman, B.T.1
Mrksich, M.2
-
8
-
-
0036199649
-
Peptide chips for the quantitative evaluation of protein kinase activity
-
B. T. Houseman, J. H. Huh, S. J. Kron, M. Mrksich, Peptide chips for the quantitative evaluation of protein kinase activity. Nat. Biotechnol. 20, 270-274 (2002).
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 270-274
-
-
Houseman, B.T.1
Huh, J.H.2
Kron, S.J.3
Mrksich, M.4
-
9
-
-
10344223002
-
Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells
-
S. H. Diks, K. Kok, T. O'Toole, D. W. Hommes, P. van Dijken, J. Joore, M. P. Peppelenbosch, Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells. J. Biol. Chem. 279, 49206-49213 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49206-49213
-
-
Diks, S.H.1
Kok, K.2
O'Toole, T.3
Hommes, D.W.4
Van Dijken, P.5
Joore, J.6
Peppelenbosch, M.P.7
-
10
-
-
33846254038
-
Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia
-
J. W. van Baal, S. H. Diks, R. J. Wanders, A. M. Rygiel, F. Milano, J. Joore, J. J. Bergman, M. P. Peppelenbosch, K. K. Krishnadath, Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia. Cancer Res. 66, 11605-11612 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 11605-11612
-
-
Van Baal, J.W.1
Diks, S.H.2
Wanders, R.J.3
Rygiel, A.M.4
Milano, F.5
Joore, J.6
Bergman, J.J.7
Peppelenbosch, M.P.8
Krishnadath, K.K.9
-
11
-
-
23944502316
-
Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn
-
M. Lowenberg, J. Tuynman, J. Bilderbeek, T. Gaber, F. Buttgereit, S. van Deventer, M. Peppelenbosch, D. Hommes, Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn. Blood 106, 1703-1710 (2005).
-
(2005)
Blood
, vol.106
, pp. 1703-1710
-
-
Lowenberg, M.1
Tuynman, J.2
Bilderbeek, J.3
Gaber, T.4
Buttgereit, F.5
Van Deventer, S.6
Peppelenbosch, M.7
Hommes, D.8
-
12
-
-
34548039258
-
Profiling of the renal kinome: A novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damage
-
M. H. de Borst, S. H. Diks, J. Bolbrinker, M. W. Schellings, M. P. van Dalen, M. P. Peppelenbosch, R. Kreutz, Y. M. Pinto, G. Navis, H. van Goor, Profiling of the renal kinome: A novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damage. Am. J. Physiol. Renal Physiol. 293, F428-F437 (2007).
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.293
-
-
De Borst, M.H.1
Diks, S.H.2
Bolbrinker, J.3
Schellings, M.W.4
Van Dalen, M.P.5
Peppelenbosch, M.P.6
Kreutz, R.7
Pinto, Y.M.8
Navis, G.9
Van Goor, H.10
-
13
-
-
4143139896
-
The mouse kinome: Discovery and comparative genetics of all mouse protein kinases
-
S. Caenepeel, G. Charydczak, S. Sudarsanam, T. Hunter, G. Manning, The mouse kinome: Discovery and comparative genetics of all mouse protein kinases. Proc. Natl. Acad. Sci. U.S.A. 101, 11707-11712 (2004).
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 11707-11712
-
-
Caenepeel, S.1
Charydczak, G.2
Sudarsanam, S.3
Hunter, T.4
Manning, G.5
-
14
-
-
37549019652
-
Use of animal models in the development of human vaccines
-
V. Gerdts, S. van den Hurk, P. Griebel, L. Babiuk, Use of animal models in the development of human vaccines. Future Med. 2, 667-675 (2007).
-
(2007)
Future Med.
, vol.2
, pp. 667-675
-
-
Gerdts, V.1
Van Den Hurk, S.2
Griebel, P.3
Babiuk, L.4
-
15
-
-
2942592575
-
Strategies for improved formulation and delivery of DNA vaccines to veterinary target species
-
S. van Drunen Littel-van den Hurk, S. L. Babiuk, L. A. Babiuk, Strategies for improved formulation and delivery of DNA vaccines to veterinary target species. Immunol. Rev. 199, 113-125 (2004).
-
(2004)
Immunol. Rev.
, vol.199
, pp. 113-125
-
-
Van Drunen Littel-Van Den Hurk, S.1
Babiuk, S.L.2
Babiuk, L.A.3
-
16
-
-
33745135437
-
Preclinical safety assessment of a DNA vaccine using particle-mediated epidermal delivery in domestic pig, minipig and mouse
-
Z. Dincer, S. Jones, R. Haworth, Preclinical safety assessment of a DNA vaccine using particle-mediated epidermal delivery in domestic pig, minipig and mouse. Exp. Toxicol. Pathol. 57, 351-357 (2006).
-
(2006)
Exp. Toxicol. Pathol.
, vol.57
, pp. 351-357
-
-
Dincer, Z.1
Jones, S.2
Haworth, R.3
-
17
-
-
0037271852
-
A road less travelled: Large animal models in immunological research
-
W. R. Hein, P. J. Griebel, A road less travelled: Large animal models in immunological research. Nat. Rev. Immunol. 3, 79-85 (2003).
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 79-85
-
-
Hein, W.R.1
Griebel, P.J.2
-
18
-
-
21144462635
-
Infection of newborn piglets with Bordetella pertussis: A new model for pertussis
-
S. Elahi, R. Brownlie, J. Korzeniowski, R. Buchanan, B. O'Connor, M. S. Peppler, S. A. Halperin, S. F. Lee, L. A. Babiuk, V. Gerdts, Infection of newborn piglets with Bordetella pertussis: A new model for pertussis. Infect. Immun. 73, 3636-3645 (2005).
-
(2005)
Infect. Immun.
, vol.73
, pp. 3636-3645
-
-
Elahi, S.1
Brownlie, R.2
Korzeniowski, J.3
Buchanan, R.4
O'Connor, B.5
Peppler, M.S.6
Halperin, S.A.7
Lee, S.F.8
Babiuk, L.A.9
Gerdts, V.10
-
19
-
-
33846280489
-
Phosphoproteome and kinome analysis: Unique perspectives on the same problem
-
S. Jalal, J. Kindrachuk, S. Napper, Phosphoproteome and kinome analysis: Unique perspectives on the same problem. Curr. Anal. Chem. 3, 1-15 (2007).
-
(2007)
Curr. Anal. Chem.
, vol.3
, pp. 1-15
-
-
Jalal, S.1
Kindrachuk, J.2
Napper, S.3
-
20
-
-
3142724031
-
Toll-like receptor signaling
-
S. Akira, K. Takeda, Toll-like receptor signaling. Nat. Rev. Immunol. 4, 499-511 (2004).
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
21
-
-
1242272100
-
Sequential phosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling
-
C. Kollewe, A. C. Mackensen, D. Neumann, J. Knop, S. Li, H. Wesche, M. U. Martin, Sequential phosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling. J. Biol. Chem. 279, 5227-5236 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5227-5236
-
-
Kollewe, C.1
Mackensen, A.C.2
Neumann, D.3
Knop, J.4
Li, S.5
Wesche, H.6
Martin, M.U.7
-
22
-
-
0242664264
-
Phosphorylation of serine 337 of NF-κB p50 is critical for DNA binding
-
S. Hou, H. Guan, R. P. Richard, Phosphorylation of serine 337 of NF-κB p50 is critical for DNA binding. J. Biol. Chem. 278, 45994-45998 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45994-45998
-
-
Hou, S.1
Guan, H.2
Richard, R.P.3
-
23
-
-
0034745420
-
NF-κB-inducing kinase regulates the processing of NF-κB2 p100
-
G. Xiao, E. W. Harhaj, S. J. Sun, NF-κB-inducing kinase regulates the processing of NF-κB2 p100. Mol. Cell 7, 401-409 (2001).
-
(2001)
Mol. Cell
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.J.3
-
24
-
-
24344468250
-
NF-κB RelA phosphorylaton regulates RelA acetylation
-
L. F. Chen, S. A. Williams, Y. Mu, H. Nakano, J. M. Duerr, L. Buckbinder, W. C. Greece, NF-κB RelA phosphorylaton regulates RelA acetylation. Mol. Cell. Biol. 25, 7966-7975 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7966-7975
-
-
Chen, L.F.1
Williams, S.A.2
Mu, Y.3
Nakano, H.4
Duerr, J.M.5
Buckbinder, L.6
Greece, W.C.7
-
25
-
-
0038660668
-
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA
-
M. J. Servant, N. Grandvaux, B. R. Tenover, D. Duguay, R. Lin, J. Hiscott, Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA. J. Biol. Chem. 278, 9441-9447 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9441-9447
-
-
Servant, M.J.1
Grandvaux, N.2
Tenover, B.R.3
Duguay, D.4
Lin, R.5
Hiscott, J.6
-
26
-
-
33845383026
-
Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide
-
N. Mookherjee, H. L. Wilson, S. Doria, Y. Popowych, R. Falsafi, J. J. Yu, S. Veatch, F. M. Roche, K. L. Brown, F. S. Brinkman, K. Hokamp, A. Potter, L. A. Babiuk, P. J. Griebel, R. E. Hancock, Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide. J. Leukoc. Biol. 80, 1563-1574 (2006).
-
(2006)
J. Leukoc. Biol.
, vol.80
, pp. 1563-1574
-
-
Mookherjee, N.1
Wilson, H.L.2
Doria, S.3
Popowych, Y.4
Falsafi, R.5
Yu, J.J.6
Veatch, S.7
Roche, F.M.8
Brown, K.L.9
Brinkman, F.S.10
Hokamp, K.11
Potter, A.12
Babiuk, L.A.13
Griebel, P.J.14
Hancock, R.E.15
-
27
-
-
0036605185
-
Analysis of protein phosphorylation using mass spectrometery: Deciphering the phosphoproteome
-
M. Mann, S. E. Ong, M. Gronborg, H. Steen, O. N. Jensen, A. Pandey, Analysis of protein phosphorylation using mass spectrometery: Deciphering the phosphoproteome. Trends Biotechnol. 20, 261-268 (2002).
-
(2002)
Trends Biotechnol.
, vol.20
, pp. 261-268
-
-
Mann, M.1
Ong, S.E.2
Gronborg, M.3
Steen, H.4
Jensen, O.N.5
Pandey, A.6
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