The effect of polymer coatings on physicochemical properties of spray-dried liposomes for nasal delivery of BSA

European Journal of Pharmaceutical Sciences

Volumn 50, Issue 3-4, 2013, Pages 312-322

  Chen, K H ^a   Di Sabatino, M ^b   Albertini, B ^b   Passerini, N ^b   Kett, V L ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Glass transition; Liposomes; Nasal; Protein; Spray dried; Trimethyl chitosan

Indexed keywords

BOVINE SERUM ALBUMIN; LIPOSOME; POLYMER;

AEROSOL; ARTICLE; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRY POWDER; ENCAPSULATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

GLASS TRANSITION; LIPOSOMES; NASAL; PROTEIN; SPRAY-DRIED; TRIMETHYL CHITOSAN;

ADHESIVENESS; ADMINISTRATION, INTRANASAL; ALGINATES; ANIMALS; ANTIGENS; CATTLE; CHITOSAN; DESICCATION; GLUCURONIC ACID; HEXURONIC ACIDS; LIPOSOMES; NASAL MUCOSA; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; SERUM ALBUMIN, BOVINE; TECHNOLOGY, PHARMACEUTICAL;

EID: 84882743133     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.07.006     Document Type: Article

References (67)

1. B. Albertini, N. Passerini, M. Di Sabatino, B. Vitali, P. Brigidi, and L. Rodriguez Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate Eur. J. Pharm. Sci. 36 2009 591 601
2. M. Amidi, S.G. Romeijn, G. Borchard, H.E. Junginger, W.E. Hennink, and W. Jiskoot Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system J. Control. Release 111 2006 107 116 (Pubitemid 43290000)
3. M. Amidi, S.G. Romeijn, J.C. Verhoef, H.E. Junginger, L. Bungener, A. Huckriede, D.J. Crommelin, and W. Jiskoot N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model Vaccine 25 2007 144 153 (Pubitemid 44855251)
4. P. Artursson, T. Lindmark, S.S. Davis, and L. Illum Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2) Pharm. Res. 11 1994 1358 1361 (Pubitemid 24287420)
5. M.R. Avadi, M.J. Zohuriaan-Mehr, P. Younessi, M. Amini, M.R. Tehrani, and A. Shafiee Optimized synthesis and characterization of N-triethyl chitosan J. Bioact. Compat. Polym. 18 2003 469 480
6. M.R. Avadi, M. Erfan, A.M.M. Sadeghi, L. Moezi, A.R. Dehpour, P. Younessi, M.R. Tehrani, and A. Shafiee N,N,Diethyl N-methyl chitosan as an enhancing agent for colon drug delivery J. Bioact. Compat. Polym. 19 2004 421 433 (Pubitemid 39371802)
7. A. Bayat, A.M.M. Sadeghi, M.R. Avadi, M. Amini, M. Rafiee-Tehrani, A. Shafiee, R. Majlesi, and H.E. Junginger Synthesis of N-N dimethyl N-ethyl chitosan as a carrier for oral delivery of peptide drugs J. Bioact. Compat. Polym. 21 2006 433 444 (Pubitemid 44267579)
8. A. Bernkop-Schnurch Mucoadhesive polymers S. Dumitriu, Polymer Biomaterial 2002 Marcel Dekker Inc. New York 147 165
9. E.G. Bligh, and W.J. Dyer A rapid method for total lipid extraction and purification Can. J. Biochem. Physiol. 37 1959 911 917
10. M.C. Bonferoni, P. Giunchedi, S. Scalia, S. Rossi, G. Sandri, and C. Caramella Chitosan gels for the vaginal delivery of lactic acid. Relevance of formulation parameters to mucoadhesion and release mechanisms AAPS Pharm. Sci. Tech. 2006 7 Article 104
11. W. Boonyo, H.E. Junginger, N. Waranuch, A. Polnok, and T. Pitaksuteepong Chitosan and trimethyl chitosan chloride (TMC) as adjuvants for inducing immune responses to ovalbumin in mice following nasal administration J Control. Release 121 3 2007 168 175 (Pubitemid 47212538)
12. G. Borchard, H.L. Lueβen, A.G. de Boer, J.C. Verhoef, C.M. Lehr, and H.E. Junginger The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. 3. Effects of chitosan glutamate and carbomer on epithelial tight junctions in vitro J. Control. Release 39 1996 131 138 (Pubitemid 26194212)
13. 2+-induced gelation in alginates and pectins: the egg-box model revisited Biomacromolecules 2 2001 1089 1096 (Pubitemid 34026883)
14. C. Callens, and J.P. Remon Evaluation of starch-maltodextrin-carbopol 974 P mixtures for the nasal delivery of insulin in rabbits J. Control. Release 66 2000 215 220 (Pubitemid 30160858)
15. J. Cao, J. Sun, X. Wang, X. Li, and Y. Deng N-Trimethyl chitosan-coated multivesicular liposomes for oxymatrine oral delivery Drug Dev. Ind. Pharm. 35 2009 1339 1347
16. K.H. Chen, W. Mueannoom, S. Gaisford, and V.L. Kett Investigation into the effect of varying L-leucine concentration on the product characteristics of spray-dried liposome powders J. Pharm. Pharmacol. 64 2012 1412 1424
17. J.H. Crowe, S.B. Leslie, and L.M. Crowe Is vitrification sufficient to preserve liposome during freeze-drying? Cryobiology 31 1994 355 366 (Pubitemid 124010998)
18. A. Dalpiaz, E. Gavini, G. Colombo, P. Russo, F. Bortolotti, L. Ferraro, S. Tanganelli, A. Scatturin, E. Menegatti, and P. Giunchedi Brain uptake of an anti-ischemic agent by nasal administration of microparticles J. Pharm. Sci. 97 11 2008 4889 4903
19. N.O. Dhoot, and M.A. Wheatley Microencapsulated liposomes in controlled drug delivery: strategies to modulate drug release and eliminate the burst effect J. Pharm. Sci. 92 2003 679 689 (Pubitemid 36258982)
20. M. di Cagno, and B. Luppi Drug ''supersaturation'' states induced by polymeric micelles and liposomes: a mechanistic investigation into permeability enhancements Eur. J. Pharm. Sci. 48 2013 775 780
21. M. Di Sabatino, B. Albertini, V.L. Kett, and N. Passerini Spray congealed lipid microparticles with high protein loading: preparation and solid state characterisation Eur. J. Pharm. Sci. 46 2012 346 356
22. S. Dimova, M.E. Brewster, M. Noppe, M. Jorissen, and P. Augustijns The use of human nasal in vitro cell systems during drug discovery and development Toxicol. In Vitro 19 2005 107 122 (Pubitemid 39592983)
23. V. Dodane, M.A. Khan, and J.R. Merwin Effect of chitosan on epithelial permeability and structure Int. J. Pharm. 182 1999 21 32 (Pubitemid 29229791)
24. A.M. Dyer, M. Hinchcliffe, P. Watts, J. Castile, I. Jabbal-Gill, R. Nankervis, A. Smith, and L. Illum Nasal delivery of insulin using novel chitosan based formulations: a comparative study in two animal models between simple chitosan formulations and chitosan nanoparticles Pharm. Res. 19 2002 998 1008 (Pubitemid 34804242)
25. R. Fernandez-Urrusuno, D. Romani, P. Calvo, J.L. Vila-Jato, and M.J. Alonso Development of a freeze-dried formulation of insulin-loaded chitosan nanoparticles intended for nasal administration STP Pharma Sci. 9 1999 429 436
26. M. Garg, T. Dutta, and N.K. Jain Stability study of stavudine-loaded o-palmitoyl anchored carbohydrate-coated liposomes AAPS Pharm. Sci. Tech. 8 2007 1 8
27. E. Gavini, G. Rassu, V. Sanna, M. Cossu, and P. Giunchedi Mucoadhesive microspheres for nasal administration of an antiemetic drug, metoclopramide: in-vitro/ex-vivo studies J. Pharm. Pharmacol. 57 2005 287 294 (Pubitemid 40314426)
28. E. Gavini, G. Rassu, T. Haukvik, C. Lanni, M. Racchi, and P. Giunchedi Mucoadhesive microspheres for nasal administration of cyclodextrins J. Drug Target. 17 2008 168 179
29. I.J. Gill, A.N. Fisher, N. Farraj, C.G. Pitt, S.S. Davis, and L. Illum Intranasal absorption of granulocyte colony stimulating factor (G-CSF) from powder formulations, in sheep Eur. J. Pharm. Sci. 6 1998 1 10 (Pubitemid 28035219)
30. P. Goldbach, H. Brochart, and A. Stamm Spray-drying of liposomes for a pulmonary administration. II. Retention of encapsulated materials Drug. Dev. Ind. Pharm. 19 1993 2623 2636 (Pubitemid 23337908)
31. J.H. Hamman, C.M. Schultz, and A.F. Kotzé N-trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells Drug. Dev. Ind. Pharm. 29 2003 161 172 (Pubitemid 36292939)
32. L. Illum Nasal drug delivery: possibilities, problems and solutions J. Control. Release 87 2003 187 198 (Pubitemid 36255456)
33. L. Illum, N.F. Farraj, and S.S. Davis Chitosan as a novel delivery system for peptide drugs Pharm. Res. 11 1994 1186 1189 (Pubitemid 24259861)
34. L. Illum, P. Watts, A.N. Fisher, I. Jabbal-Gill, and S.S. Davis Novel chitosan based delivery systems for nasal administration of a LHRH-analogue STP Pharma Sci. 10 2000 89 94 (Pubitemid 30126791)
35. A.K. Jain, K.B. Chalasani, R.K. Khar, F.J. Ahmed, and P.V. Diwan Muco-adhesive multivesicular liposomes as an effective carrier for transmucosal insulin delivery J. Drug Target. 15 2007 417 427 (Pubitemid 47073057)
36. A. Janda, and A. Casadevall Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure Mol. Immunol. 47 2010 1421 1425
37. Y. Kato, T. Hosokawa, E. Hayakawa, and K. Ito Influence of liposomes on tryptic digestion of insulin Biol. Pharm. Bull. 16 1993 457 461 (Pubitemid 23208662)
38. S.L. Law, K.J. Huang, V.H.Y. Chou, and J.Y. Cherng Enhancement of nasal absorption of calcitonin loaded in liposomes J. liposome Res. 11 2001 164 174
39. V.H. Lee, and A. Yamamoto Penetration and enzymatic barriers of peptide and protein absorption Adv. Drug Deliv. Rev. 4 1990 171 207
40. V.H. Lee, A. Yamamoto, and U.B. Kompella Mucosal penetration enhancers for facilitation of peptide and protein drug absorption Crit. Rev. Ther. Drug Carrier Syst. 8 1991 91 192
41. W.K. Lee, J.S. Ko, and H.M. Kim Effect of electrostatic interaction on the adsorption of globular proteins on octacalcium phosphate crystal film J. Colloid Interface Sci. 246 2002 70 77
42. J. Liu, J. Tian, X. Tian, Z. Hu, and X. Chen Interaction of isofraxidin with human serum albumin Bioorg. Med. Chem. 12 2004 469 474 (Pubitemid 38067254)
43. C. Louis-Jeune, M.A. Andrade-Navarro, and C. Perez-Iratxeta Prediction of protein secondary structure from circular dichroism using theoretically derived spectra Proteins 80 2 2012 374 381 K2D3 < http://www.ogic.ca/projects/k2d3/ > (accessed 14.12.12)
44. B. Luppi, F. Bigucci, T. Cerchiara, and V. Zecchi Chitosan-based hydrogels for nasal drug delivery: from inserts to nanoparticles Exp. Op. Drug Del. 7 2010 811 828
45. U. Massing, S. Cicko, and V. Ziroli Dual asymmetric centrifugation (DAC)- a new technique for liposome preparation J. Control. Release 125 2008 16 24 (Pubitemid 350198678)
46. A. Minne, H. Boireau, M.J. Horta, and R. Vanbever Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients Eur. J. Pharm. Biopharm. 3 2008 839 844
47. A.K. Mitra, and R. Krishnamoorthy Prodrugs for nasal drug delivery Adv. Drug Deliv. Rev. 29 1998 135 146 (Pubitemid 28044090)
48. M. Mosca, A. Ceglie, and L. Ambrosone Effect of membrane composition on lipid oxidation in liposomes Chem. Phys. Lipids 164 2011 158 165
49. K. Murramatsu, Y. Maitani, K. Takayama, and T. Nagai The relationship between the rigidity of the liposomal membrane and the absorption of insulin after nasal administration of liposomes modified with an enhancer containing insulin in rabbits Drug Dev. Ind. Pharm. 25 1999 1099 1105 (Pubitemid 29477867)
50. D.T. O'Hagan, and L. Illum Absorption of peptides and proteins from the respiratory tract and the potential for development of locally administered vaccine Crit. Rev. Ther. Drug Carrier Syst. 7 1990 35 97 (Pubitemid 20355577)
51. S.B. Patil, and K.K. Sawant Development, optimization and in vitro evaluation of alginate mucoadhesive microspheres of carvedilol for nasal delivery J. Microencapsul. 26 2009 432 443
52. A. Pires, A. Fortuna, G. Alves, and A. Falcão Intranasal drug delivery: how, why, and what for? J. Pharm. Pharm. Sci. 12 2009 288 311
53. A. Polnok, G. Borchard, J.C. Verhoef, N. Sarisuta, and H.E. Junginger Influence of methylation process on the degree of quaternization of N-trimethyl chitosan chloride Eur. J. Pharm. Biopharm. 57 2004 77 83 (Pubitemid 38058805)
54. A.M.M. Sadeghi, F.A. Dorkoosh, M.R. Avadi, M. Weinhold, A. Bayat, F. Delie, R. Gurny, B. Larijani, M. Rafiee-Tehrani, and H.E. Junginger Permeation enhancer effect of chitosan and chitosan derivates: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption inCaco-2 cells Eur. J. Pharm. Biopharm. 70 2008 270 278
55. A.B. Sieval, M. Thanou, A.F. Kotze, J.E. Verhoef, J. Brussee, and H.E. Junginger Preparation and NMR characterization of highly substituted N-trimethyl chitosan chloride Carbohydr. Polym. 36 1998 157 165 (Pubitemid 128399589)
56. J. Smith, E. Wood, and M. Dornish Effect of chitosan on epithelial cell tight junctions Pharm. Res. 21 2004 43 49 (Pubitemid 38122290)
57. J.C. Stewart Colorimetric determination of phospholipids with ammonium ferrothiocyanate Anal. Biochem. 104 1980 10 14 (Pubitemid 10045896)
58. G. Strauss, P. Schurtenberger, and H. Hauser The interaction of saccharides with lipid bilayer vesicles: stabilization during freeze-thawing and freeze-drying Biochim. Biophys. Acta 858 1986 169 180
59. H. Takeuchi, H. Yamamoto, T. Toyoda, H. Toyobuku, T. Hino, and Y. Kawashima Physical stability of size controlled small unilamellar liposomes coated with a modified polyvinyl alcohol Int. J. Pharm. 164 1998 103 111 (Pubitemid 28160102)
60. H. Takeuchi, Y. Matsui, H. Sugihara, H. Yamamoto, and Y. Kawashima Effectiveness of submicron sized, chitosan-coated liposomes in oral administration of peptide drugs Int. J. Pharm. 303 2005 160 170 (Pubitemid 41318033)
61. M.M. Thanou, A.F. Kotze', T. Scharringhausen, H.L. Luesen, A.G. De Boer, J.C. Verhoef, and H.E. Junginger Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers J. Control. Release 64 2000 15 25 (Pubitemid 30035304)
62. K. Thongborisute, H. Takeuchi, H. Yamamoto, and Y. Kawashima Visualization of the penetrative and mucoadhesive properties of chitosan and chitosan-coated liposomes through the rat intestine J. Liposome Res. 2 2006 127 141 (Pubitemid 43861149)
63. S. Tiwari, A.K. Goyal, N. Mishra, K. Khatri, B. Vaidya, A. Mehta, Y. Wu, and S.P. Vyas Development and characterization of novel carrier gel core liposomes based transmission blocking malaria vaccine J Control. Release 140 2009 157 165
64. M.I. Ugwoke, R.U. Agu, N. Verbeke, and R. Kinget Nasal mucoadhesive drug delivery: background, applications, trends and future perspectives Adv. Drug Deliv. Rev. 57 2005 1640 1665 (Pubitemid 41443473)
65. M. Umrethia, V.L. Kett, G.P. Andrews, R.K. Malcolm, and A.D. Woolfson Selection of an analytical method for evaluating bovine serum albumin concentrations in pharmaceutical polymeric formulations J. Pharm. Biomed. Anal. 51 2010 1175 1179
66. C. Wadell, E. Björk, and O. Camber Nasal drug delivery-evaluation of an in vitro model using porcine nasal mucosa Eur. J. Pharm. Sci. 7 3 1999 197 206 (Pubitemid 29015736)
67. J. Wang, Y. Tabata, and K. Morimoto Aminated gelatin microspheres as a nasal delivery system for peptide drugs: Evaluation of in vitro release and in vivo absorption in rats J. Control. Release 113 2006 31 37 (Pubitemid 43833468)