메뉴 건너뛰기




Volumn 5, Issue 3, 2013, Pages 1049-1071

Glioblastoma-initiating cells: Relationship with neural stem cells and the micro-environment

Author keywords

Cancer stem cells; Glioblastoma; Micro environment; Neural stem cells; Subventricular zone

Indexed keywords

CANCER CELL; CANCER STEM CELL; CARCINOGENESIS; CELL DEDIFFERENTIATION; CELL INTERACTION; CELL POPULATION; GLIOBLASTOMA; GLIOBLASTOMA INITIATING CELL; HUMAN; IMMUNE SYSTEM; MICROGLIA; NEURAL STEM CELL; NONHUMAN; REVIEW; STEM CELL NICHE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT;

EID: 84882713028     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers5031049     Document Type: Review
Times cited : (76)

References (133)
  • 2
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp, R.; Hegi, M.E.; Mason, W.P.; van den Bent, M.J.; Taphoorn, M.J.; Janzer, R.C.; Ludwin, S.K.; Allgeier, A.; Fisher, B.; Belanger, K.; et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009, 10, 459-466.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    van den Bent, M.J.4    Taphoorn, M.J.5    Janzer, R.C.6    Ludwin, S.K.7    Allgeier, A.8    Fisher, B.9    Belanger, K.10
  • 3
    • 20444456659 scopus 로고    scopus 로고
    • The role of radio- and chemotherapy in glioblastoma
    • Stupp, R.; Weber, D.C. The role of radio- and chemotherapy in glioblastoma. Onkologie 2005, 28, 315-317.
    • (2005) Onkologie , vol.28 , pp. 315-317
    • Stupp, R.1    Weber, D.C.2
  • 5
    • 2542590281 scopus 로고    scopus 로고
    • Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients
    • Ostermann, S.; Csajka, C.; Buclin, T.; Leyvraz, S.; Lejeune, F.; Decosterd, L.A.; Stupp, R. Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. Clin. Cancer Res. 2004, 10, 3728-3736.
    • (2004) Clin. Cancer Res , vol.10 , pp. 3728-3736
    • Ostermann, S.1    Csajka, C.2    Buclin, T.3    Leyvraz, S.4    Lejeune, F.5    Decosterd, L.A.6    Stupp, R.7
  • 6
    • 72549116837 scopus 로고    scopus 로고
    • The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: Potential implications for the current approach to chemoradiation
    • Portnow, J.; Badie, B.; Chen, M.; Liu, A.; Blanchard, S.; Synold, T.W. The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: Potential implications for the current approach to chemoradiation. Clin. Cancer Res. 2009, 15, 7092-7098.
    • (2009) Clin. Cancer Res , vol.15 , pp. 7092-7098
    • Portnow, J.1    Badie, B.2    Chen, M.3    Liu, A.4    Blanchard, S.5    Synold, T.W.6
  • 7
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak, R.G.; Hoadley, K.A.; Purdom, E.; Wang, V.; Qi, Y.; Wilkerson, M.D.; Miller, C.R.; Ding, L.; Golub, T.; Mesirov, J.P.; et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17, 98-110.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6    Miller, C.R.7    Ding, L.8    Golub, T.9    Mesirov, J.P.10
  • 12
    • 45249119952 scopus 로고    scopus 로고
    • Glioma stem cells: A midterm exam
    • Stiles, C.D.; Rowitch, D.H. Glioma stem cells: A midterm exam. Neuron 2008, 58, 832-846.
    • (2008) Neuron , vol.58 , pp. 832-846
    • Stiles, C.D.1    Rowitch, D.H.2
  • 13
    • 33750541962 scopus 로고    scopus 로고
    • Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype
    • Salmaggi, A.; Boiardi, A.; Gelati, M.; Russo, A.; Calatozzolo, C.; Ciusani, E.; Sciacca, F.L.;Ottolina, A.; Parati, E.A.; la Porta, C.; et al. Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia 2006, 54, 850-860.
    • (2006) Glia , vol.54 , pp. 850-860
    • Salmaggi, A.1    Boiardi, A.2    Gelati, M.3    Russo, A.4    Calatozzolo, C.5    Ciusani, E.6    Sciacca, F.L.7    Ottolina, A.8    Parati, E.A.9    la Porta, C.10
  • 17
    • 0028361594 scopus 로고
    • Long-distance neuronal migration in the adult mammalian brain
    • Lois, C.; Alvarez-Buylla, A. Long-distance neuronal migration in the adult mammalian brain. Science 1994, 264, 1145-1148.
    • (1994) Science , vol.264 , pp. 1145-1148
    • Lois, C.1    Alvarez-Buylla, A.2
  • 18
    • 0027291286 scopus 로고
    • Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone
    • Luskin, M.B. Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron 1993, 11, 173-189.
    • (1993) Neuron , vol.11 , pp. 173-189
    • Luskin, M.B.1
  • 22
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 23
    • 0036791177 scopus 로고    scopus 로고
    • Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt
    • Uhrbom, L.; Dai, C.; Celestino, J.C.; Rosenblum, M.K.; Fuller, G.N.; Holland, E.C. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res. 2002, 62, 5551-5558.
    • (2002) Cancer Res , vol.62 , pp. 5551-5558
    • Uhrbom, L.1    Dai, C.2    Celestino, J.C.3    Rosenblum, M.K.4    Fuller, G.N.5    Holland, E.C.6
  • 24
    • 19044397160 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
    • Bachoo, R.M.; Maher, E.A.; Ligon, K.L.; Sharpless, N.E.; Chan, S.S.; You, M.J.; Tang, Y.; DeFrances, J.; Stover, E.; Weissleder, R.; et al. Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 2002, 1, 269-277.
    • (2002) Cancer Cell , vol.1 , pp. 269-277
    • Bachoo, R.M.1    Maher, E.A.2    Ligon, K.L.3    Sharpless, N.E.4    Chan, S.S.5    You, M.J.6    Tang, Y.7    Defrances, J.8    Stover, E.9    Weissleder, R.10
  • 25
    • 84873721875 scopus 로고    scopus 로고
    • Akt and c-Myc induce stem-cell markers in mature primary p53-/- astrocytes and render these cells gliomagenic in the brain of immunocompetent mice
    • Radke, J.; Bortolussi, G.; Pagenstecher, A. Akt and c-Myc induce stem-cell markers in mature primary p53-/- astrocytes and render these cells gliomagenic in the brain of immunocompetent mice. PLoS One 2013, 8, e56691.
    • (2013) PLoS One , vol.e56691 , pp. 8
    • Radke, J.1    Bortolussi, G.2    Pagenstecher, A.3
  • 26
    • 77953215319 scopus 로고    scopus 로고
    • Invasive glioblastoma cells acquire stemness and increased Akt activation
    • Molina, J.R.; Hayashi, Y.; Stephens, C.; Georgescu, M.M. Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia 2010, 12, 453-463.
    • (2010) Neoplasia , vol.12 , pp. 453-463
    • Molina, J.R.1    Hayashi, Y.2    Stephens, C.3    Georgescu, M.M.4
  • 28
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • Holland, E.C.; Celestino, J.; Dai, C.; Schaefer, L.; Sawaya, R.E.; Fuller, G.N. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat. Genet. 2000, 25, 55-57.
    • (2000) Nat. Genet , vol.25 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5    Fuller, G.N.6
  • 30
    • 70449717544 scopus 로고    scopus 로고
    • Methods for analysis of brain tumor stem cell and neural stem cell self-renewal
    • Nakano, I.; Kornblum, H.I. Methods for analysis of brain tumor stem cell and neural stem cell self-renewal. Methods Mol. Biol. 2009, 568, 37-
    • (2009) Methods Mol. Biol , vol.568 , pp. 37
    • Nakano, I.1    Kornblum, H.I.2
  • 32
    • 6044221204 scopus 로고    scopus 로고
    • Cancer stem cells in nervous system tumors
    • Singh, S.K.; Clarke, I.D.; Hide, T.; Dirks, P.B. Cancer stem cells in nervous system tumors. Oncogene 2004, 23, 7267-7273.
    • (2004) Oncogene , vol.23 , pp. 7267-7273
    • Singh, S.K.1    Clarke, I.D.2    Hide, T.3    Dirks, P.B.4
  • 35
    • 38449087465 scopus 로고    scopus 로고
    • Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype
    • Lim, D.A.; Cha, S.; Mayo, M.C.; Chen, M.H.; Keles, E.; VandenBerg, S.; Berger, M.S. Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype. Neuro-oncology 2007, 9, 424-429.
    • (2007) Neuro-oncology , vol.9 , pp. 424-429
    • Lim, D.A.1    Cha, S.2    Mayo, M.C.3    Chen, M.H.4    Keles, E.5    Vandenberg, S.6    Berger, M.S.7
  • 36
    • 23644443053 scopus 로고    scopus 로고
    • Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
    • Zhu, Y.; Guignard, F.; Zhao, D.; Liu, L.; Burns, D.K.; Mason, R.P.; Messing, A.; Parada, L.F. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 2005, 8, 119-130.
    • (2005) Cancer Cell , vol.8 , pp. 119-130
    • Zhu, Y.1    Guignard, F.2    Zhao, D.3    Liu, L.4    Burns, D.K.5    Mason, R.P.6    Messing, A.7    Parada, L.F.8
  • 39
    • 65649142176 scopus 로고    scopus 로고
    • Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
    • Wang, Y.; Yang, J.; Zheng, H.; Tomasek, G.J.; Zhang, P.; McKeever, P.E.; Lee, E.Y.; Zhu, Y. Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 2009, 15, 514-526.
    • (2009) Cancer Cell , vol.15 , pp. 514-526
    • Wang, Y.1    Yang, J.2    Zheng, H.3    Tomasek, G.J.4    Zhang, P.5    McKeever, P.E.6    Lee, E.Y.7    Zhu, Y.8
  • 40
    • 33745880884 scopus 로고    scopus 로고
    • PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling
    • Jackson, E.L.; Garcia-Verdugo, J.M.; Gil-Perotin, S.; Roy, M.; Quinones-Hinojosa, A.; VandenBerg, S.; Alvarez-Buylla, A. PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron 2006, 51, 187-199.
    • (2006) Neuron , vol.51 , pp. 187-199
    • Jackson, E.L.1    Garcia-Verdugo, J.M.2    Gil-Perotin, S.3    Roy, M.4    Quinones-Hinojosa, A.5    Vandenberg, S.6    Alvarez-Buylla, A.7
  • 44
    • 0029860591 scopus 로고    scopus 로고
    • Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
    • Weiss, S.; Dunne, C.; Hewson, J.; Wohl, C.; Wheatley, M.; Peterson, A.C.; Reynolds, B.A. Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J. Neurosci. 1996, 16, 7599-7609.
    • (1996) J. Neurosci , vol.16 , pp. 7599-7609
    • Weiss, S.1    Dunne, C.2    Hewson, J.3    Wohl, C.4    Wheatley, M.5    Peterson, A.C.6    Reynolds, B.A.7
  • 46
    • 84863730854 scopus 로고    scopus 로고
    • Innate neural stem cell heterogeneity determines the patterning of glioma formation in children
    • Lee da, Y.; Gianino, S.M.; Gutmann, D.H. Innate neural stem cell heterogeneity determines the patterning of glioma formation in children. Cancer Cell 2012, 22, 131-138.
    • (2012) Cancer Cell , vol.22 , pp. 131-138
    • da Lee, Y.1    Gianino, S.M.2    Gutmann, D.H.3
  • 48
    • 66249100578 scopus 로고    scopus 로고
    • Common astrocytic programs during brain development, injury and cancer
    • Silver, D.J.; Steindler, D.A. Common astrocytic programs during brain development, injury and cancer. Trends Neurosci. 2009, 32, 303-311.
    • (2009) Trends Neurosci , vol.32 , pp. 303-311
    • Silver, D.J.1    Steindler, D.A.2
  • 50
    • 77954387918 scopus 로고    scopus 로고
    • Glial progenitors in the brainstem give rise to malignant gliomas by platelet-derived growth factor stimulation
    • Masui, K.; Suzuki, S.O.; Torisu, R.; Goldman, J.E.; Canoll, P.; Iwaki, T. Glial progenitors in the brainstem give rise to malignant gliomas by platelet-derived growth factor stimulation. Glia 2010, 58, 1050-1065.
    • (2010) Glia , vol.58 , pp. 1050-1065
    • Masui, K.1    Suzuki, S.O.2    Torisu, R.3    Goldman, J.E.4    Canoll, P.5    Iwaki, T.6
  • 53
    • 67349108288 scopus 로고    scopus 로고
    • Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma
    • Lindberg, N.; Kastemar, M.; Olofsson, T.; Smits, A.; Uhrbom, L. Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma. Oncogene 2009, 28, 2266-2275.
    • (2009) Oncogene , vol.28 , pp. 2266-2275
    • Lindberg, N.1    Kastemar, M.2    Olofsson, T.3    Smits, A.4    Uhrbom, L.5
  • 55
    • 0034622930 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells
    • Kondo, T.; Raff, M. Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 2000, 289, 1754-1757.
    • (2000) Science , vol.289 , pp. 1754-1757
    • Kondo, T.1    Raff, M.2
  • 57
    • 33644820339 scopus 로고    scopus 로고
    • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
    • Phillips, H.S.; Kharbanda, S.; Chen, R.; Forrest, W.F.; Soriano, R.H.; Wu, T.D.; Misra, A.; Nigro, J.M.; Colman, H.; Soroceanu, L.; et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006, 9, 157-173.
    • (2006) Cancer Cell , vol.9 , pp. 157-173
    • Phillips, H.S.1    Kharbanda, S.2    Chen, R.3    Forrest, W.F.4    Soriano, R.H.5    Wu, T.D.6    Misra, A.7    Nigro, J.M.8    Colman, H.9    Soroceanu, L.10
  • 59
    • 79953220742 scopus 로고    scopus 로고
    • Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation
    • Fumagalli, M.; Daniele, S.; Lecca, D.; Lee, P.R.; Parravicini, C.; Fields, R.D.; Rosa, P.; Antonucci, F.; Verderio, C.; Trincavelli, M.L.; et al. Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation. J. Biol. Chem. 2011, 286, 10593-10604.
    • (2011) J. Biol. Chem , vol.286 , pp. 10593-10604
    • Fumagalli, M.1    Daniele, S.2    Lecca, D.3    Lee, P.R.4    Parravicini, C.5    Fields, R.D.6    Rosa, P.7    Antonucci, F.8    Verderio, C.9    Trincavelli, M.L.10
  • 62
    • 63849335831 scopus 로고    scopus 로고
    • Flow cytometry and in vitro analysis of human glioma-associated macrophages. Laboratory investigation
    • Parney, I.F.; Waldron, J.S.; Parsa, A.T. Flow cytometry and in vitro analysis of human glioma-associated macrophages. Laboratory investigation. J. Neurosurg. 2009, 110, 572-582.
    • (2009) J. Neurosurg , vol.110 , pp. 572-582
    • Parney, I.F.1    Waldron, J.S.2    Parsa, A.T.3
  • 65
    • 67649448823 scopus 로고    scopus 로고
    • Tumor-associated macrophage/microglia infiltration in human gliomas is correlated with MCP-3, but not MCP-1
    • Okada, M.; Saio, M.; Kito, Y.; Ohe, N.; Yano, H.; Yoshimura, S.; Iwama, T.; Takami, T. Tumor-associated macrophage/microglia infiltration in human gliomas is correlated with MCP-3, but not MCP-1. Int. J. Oncol. 2009, 34, 1621-1627.
    • (2009) Int. J. Oncol , vol.34 , pp. 1621-1627
    • Okada, M.1    Saio, M.2    Kito, Y.3    Ohe, N.4    Yano, H.5    Yoshimura, S.6    Iwama, T.7    Takami, T.8
  • 66
    • 0028225493 scopus 로고
    • Colony stimulating factor-1 expression in human glioma
    • Alterman, R.L.; Stanley, E.R. Colony stimulating factor-1 expression in human glioma. Mol. Chem. Neuropathol. 1994, 21, 177-188.
    • (1994) Mol. Chem. Neuropathol , vol.21 , pp. 177-188
    • Alterman, R.L.1    Stanley, E.R.2
  • 67
    • 24644490056 scopus 로고    scopus 로고
    • Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2
    • Markovic, D.S.; Glass, R.; Synowitz, M.; Rooijen, N.; Kettenmann, H. Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J. Neuropathol. Exp. Neurol. 2005, 64, 754-762.
    • (2005) J. Neuropathol. Exp. Neurol , vol.64 , pp. 754-762
    • Markovic, D.S.1    Glass, R.2    Synowitz, M.3    Rooijen, N.4    Kettenmann, H.5
  • 70
    • 34249054990 scopus 로고    scopus 로고
    • CD4+ CD25+ FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas
    • El Andaloussi, A.; Lesniak, M.S. CD4+ CD25+ FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas. J. Neurooncol. 2007, 83, 145-152.
    • (2007) J. Neurooncol , vol.83 , pp. 145-152
    • El Andaloussi, A.1    Lesniak, M.S.2
  • 71
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • Jordan, J.T.; Sun, W.; Hussain, S.F.; DeAngulo, G.; Prabhu, S.S.; Heimberger, A.B. Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol. Immunother. 2008, 57, 123-131.
    • (2008) Cancer Immunol. Immunother , vol.57 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    Deangulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 72
    • 67649966553 scopus 로고    scopus 로고
    • Site-specific anti-tumor immunity: Differences in DC function, TGF-beta production and numbers of intratumoral Foxp3+ Treg
    • Biollaz, G.; Bernasconi, L.; Cretton, C.; Puntener, U.; Frei, K.; Fontana, A.; Suter, T. Site-specific anti-tumor immunity: Differences in DC function, TGF-beta production and numbers of intratumoral Foxp3+ Treg. Eur. J. Immunol. 2009, 39, 1323-1333.
    • (2009) Eur. J. Immunol , vol.39 , pp. 1323-1333
    • Biollaz, G.1    Bernasconi, L.2    Cretton, C.3    Puntener, U.4    Frei, K.5    Fontana, A.6    Suter, T.7
  • 73
    • 77954368572 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells
    • Chirasani, S.R.; Sternjak, A.; Wend, P.; Momma, S.; Campos, B.; Herrmann, I.M.; Graf, D.; Mitsiadis, T.; Herold-Mende, C.; Besser, D.; et al. Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells. Brain 2010, 133, 1961-1972.
    • (2010) Brain , vol.133 , pp. 1961-1972
    • Chirasani, S.R.1    Sternjak, A.2    Wend, P.3    Momma, S.4    Campos, B.5    Herrmann, I.M.6    Graf, D.7    Mitsiadis, T.8    Herold-Mende, C.9    Besser, D.10
  • 74
    • 33745778950 scopus 로고    scopus 로고
    • Glial progenitors in adult white matter are driven to form malignant gliomas by platelet-derived growth factor-expressing retroviruses
    • Assanah, M.; Lochhead, R.; Ogden, A.; Bruce, J.; Goldman, J.; Canoll, P. Glial progenitors in adult white matter are driven to form malignant gliomas by platelet-derived growth factor-expressing retroviruses. J. Neurosci. 2006, 26, 6781-6790.
    • (2006) J. Neurosci , vol.26 , pp. 6781-6790
    • Assanah, M.1    Lochhead, R.2    Ogden, A.3    Bruce, J.4    Goldman, J.5    Canoll, P.6
  • 77
    • 70349501957 scopus 로고    scopus 로고
    • Chemokine CXC receptor 4-Mediated glioma tumor tracking by bone marrow-Derived neural progenitor/stem cells
    • Xu, Q.; Yuan, X.; Xu, M.; McLafferty, F.; Hu, J.; Lee, B.S.; Liu, G.; Zeng, Z.; Black, K.L.; Yu, J.S. Chemokine CXC receptor 4-Mediated glioma tumor tracking by bone marrow-Derived neural progenitor/stem cells. Mol. Cancer Ther. 2009, 8, 2746-2753.
    • (2009) Mol. Cancer Ther , vol.8 , pp. 2746-2753
    • Xu, Q.1    Yuan, X.2    Xu, M.3    McLafferty, F.4    Hu, J.5    Lee, B.S.6    Liu, G.7    Zeng, Z.8    Black, K.L.9    Yu, J.S.10
  • 78
    • 70350710001 scopus 로고    scopus 로고
    • Reciprocal effects of conditioned medium on cultured glioma cells and neural stem cells
    • Chen, F.X.; Ren, W.W.; Yang, Y.; Shen, D.; Zong, Y.; Xu, S.; Duan, Y.; Qian, Y.; Ji, Y. Reciprocal effects of conditioned medium on cultured glioma cells and neural stem cells. J. Clin. Neurosci. 2009, 16, 1619-1623.
    • (2009) J. Clin. Neurosci , vol.16 , pp. 1619-1623
    • Chen, F.X.1    Ren, W.W.2    Yang, Y.3    Shen, D.4    Zong, Y.5    Xu, S.6    Duan, Y.7    Qian, Y.8    Ji, Y.9
  • 81
    • 50849142558 scopus 로고    scopus 로고
    • Adult SVZ stem cells lie in a vascular niche: A quantitative analysis of niche cell-cell interactions
    • Shen, Q.; Wang, Y.; Kokovay, E.; Lin, G.; Chuang, S.M.; Goderie, S.K.; Roysam, B.; Temple, S. Adult SVZ stem cells lie in a vascular niche: A quantitative analysis of niche cell-cell interactions. Cell Stem Cell 2008, 3, 289-300.
    • (2008) Cell Stem Cell , vol.3 , pp. 289-300
    • Shen, Q.1    Wang, Y.2    Kokovay, E.3    Lin, G.4    Chuang, S.M.5    Goderie, S.K.6    Roysam, B.7    Temple, S.8
  • 83
    • 34648821254 scopus 로고    scopus 로고
    • Making a tumour's bed: Glioblastoma stem cells and the vascular niche
    • Gilbertson, R.J.; Rich, J.N. Making a tumour's bed: Glioblastoma stem cells and the vascular niche. Nat. Rev. Cancer 2007, 7, 733-736.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 733-736
    • Gilbertson, R.J.1    Rich, J.N.2
  • 84
    • 34248550985 scopus 로고    scopus 로고
    • Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors
    • Folkins, C.; Man, S.; Xu, P.; Shaked, Y.; Hicklin, D.J.; Kerbel, R.S. Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors. Cancer Res. 2007, 67, 3560-3564.
    • (2007) Cancer Res , vol.67 , pp. 3560-3564
    • Folkins, C.1    Man, S.2    Xu, P.3    Shaked, Y.4    Hicklin, D.J.5    Kerbel, R.S.6
  • 85
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen, P.Y.; Kesari, S. Malignant gliomas in adults. N. Engl. J. Med. 2008, 359, 492-507.
    • (2008) N. Engl. J. Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 86
    • 64149101418 scopus 로고    scopus 로고
    • Tumor initiating cells in malignant gliomas: Biology and implications for therapy
    • Hadjipanayis, C.G.; van Meir, E.G. Tumor initiating cells in malignant gliomas: Biology and implications for therapy. J. Mol. Med. 2009, 87, 363-374.
    • (2009) J. Mol. Med , vol.87 , pp. 363-374
    • Hadjipanayis, C.G.1    van Meir, E.G.2
  • 88
    • 8644290263 scopus 로고    scopus 로고
    • Stem cell factor is a chemoattractant and a survival factor for CNS stem cells
    • Erlandsson, A.; Larsson, J.; Forsberg-Nilsson, K. Stem cell factor is a chemoattractant and a survival factor for CNS stem cells. Exp. Cell Res. 2004, 301, 201-210.
    • (2004) Exp. Cell Res , vol.301 , pp. 201-210
    • Erlandsson, A.1    Larsson, J.2    Forsberg-Nilsson, K.3
  • 90
    • 33344456910 scopus 로고    scopus 로고
    • PEDF: Bridging neurovascular interactions in the stem cell niche
    • Pumiglia, K.; Temple, S. PEDF: Bridging neurovascular interactions in the stem cell niche. Nat. Neurosci. 2006, 9, 299-300.
    • (2006) Nat. Neurosci , vol.9 , pp. 299-300
    • Pumiglia, K.1    Temple, S.2
  • 92
    • 77956241246 scopus 로고    scopus 로고
    • Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling
    • Kokovay, E.; Goderie, S.; Wang, Y.; Lotz, S.; Lin, G.; Sun, Y.; Roysam, B.; Shen, Q.; Temple, S. Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell 2010, 7, 163-173.
    • (2010) Cell Stem Cell , vol.7 , pp. 163-173
    • Kokovay, E.1    Goderie, S.2    Wang, Y.3    Lotz, S.4    Lin, G.5    Sun, Y.6    Roysam, B.7    Shen, Q.8    Temple, S.9
  • 93
    • 79851501293 scopus 로고    scopus 로고
    • A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target
    • Schulte, A.; Gunther, H.S.; Phillips, H.S.; Kemming, D.; Martens, T.; Kharbanda, S.; Soriano, R.H.; Modrusan, Z.; Zapf, S.; Westphal, M.; et al. A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target. Glia 2011, 59, 590-602.
    • (2011) Glia , vol.59 , pp. 590-602
    • Schulte, A.1    Gunther, H.S.2    Phillips, H.S.3    Kemming, D.4    Martens, T.5    Kharbanda, S.6    Soriano, R.H.7    Modrusan, Z.8    Zapf, S.9    Westphal, M.10
  • 94
    • 23244435467 scopus 로고    scopus 로고
    • How do stem cells find their way home?
    • Lapidot, T.; Dar, A.; Kollet, O. How do stem cells find their way home? Blood 2005, 106, 1901-1910.
    • (2005) Blood , vol.106 , pp. 1901-1910
    • Lapidot, T.1    Dar, A.2    Kollet, O.3
  • 95
    • 33845383924 scopus 로고    scopus 로고
    • Modeling the neurovascular niche: VEGF- and BDNF-mediated cross-talk between neural stem cells and endothelial cells: An in vitro study
    • Li, Q.; Ford, M.C.; Lavik, E.B.; Madri, J.A. Modeling the neurovascular niche: VEGF- and BDNF-mediated cross-talk between neural stem cells and endothelial cells: An in vitro study. J. Neurosci. Res. 2006, 84, 1656-1668.
    • (2006) J. Neurosci. Res , vol.84 , pp. 1656-1668
    • Li, Q.1    Ford, M.C.2    Lavik, E.B.3    Madri, J.A.4
  • 97
    • 70349747011 scopus 로고    scopus 로고
    • Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1
    • Folkins, C.; Shaked, Y.; Man, S.; Tang, T.; Lee, C.R.; Zhu, Z.; Hoffman, R.M.; Kerbel, R.S. Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1. Cancer Res. 2009, 69, 7243-7251.
    • (2009) Cancer Res , vol.69 , pp. 7243-7251
    • Folkins, C.1    Shaked, Y.2    Man, S.3    Tang, T.4    Lee, C.R.5    Zhu, Z.6    Hoffman, R.M.7    Kerbel, R.S.8
  • 98
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston, J.M.; Li, Z.; McLendon, R.E.; Hjelmeland, A.B.; Rich, J.N. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009, 8, 3274-3284.
    • (2009) Cell Cycle , vol.8 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3    Hjelmeland, A.B.4    Rich, J.N.5
  • 99
    • 67649118749 scopus 로고    scopus 로고
    • Turning cancer stem cells inside out: An exploration of glioma stem cell signaling pathways
    • Li, Z.; Wang, H.; Eyler, C.E.; Hjelmeland, A.B.; Rich, J.N. Turning cancer stem cells inside out: an exploration of glioma stem cell signaling pathways. J. Biol. Chem. 2009, 284, 16705-16709.
    • (2009) J. Biol. Chem , vol.284 , pp. 16705-16709
    • Li, Z.1    Wang, H.2    Eyler, C.E.3    Hjelmeland, A.B.4    Rich, J.N.5
  • 100
    • 0037228960 scopus 로고    scopus 로고
    • PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter
    • Pore, N.; Liu, S.; Haas-Kogan, D.A.; O'Rourke, D.M.; Maity, A. PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter. Cancer Res. 2003, 63, 236-241.
    • (2003) Cancer Res , vol.63 , pp. 236-241
    • Pore, N.1    Liu, S.2    Haas-Kogan, D.A.3    O'Rourke, D.M.4    Maity, A.5
  • 101
    • 67649200247 scopus 로고    scopus 로고
    • Anti-VEGF therapies for malignant glioma: Treatment effects and escape mechanisms
    • Miletic, H.; Niclou, S.P.; Johansson, M.; Bjerkvig, R. Anti-VEGF therapies for malignant glioma: Treatment effects and escape mechanisms. Expert Opin. Ther. Targets 2009, 13, 455-468.
    • (2009) Expert Opin. Ther. Targets , vol.13 , pp. 455-468
    • Miletic, H.1    Niclou, S.P.2    Johansson, M.3    Bjerkvig, R.4
  • 102
    • 76949086699 scopus 로고    scopus 로고
    • Available online, (accessed on 25 July 2013)
    • ClinicalTrials.gov Homepage. Available online: http://www.clinicaltrials.gov/ (accessed on 25 July 2013).
    • ClinicalTrials.gov Homepage
  • 105
    • 33947665095 scopus 로고    scopus 로고
    • Progenitor cells and adult neurogenesis in neurodegenerative diseases and injuries of the basal ganglia
    • Curtis, M.A.; Eriksson, P.S.; Faull, R.L.M. Progenitor cells and adult neurogenesis in neurodegenerative diseases and injuries of the basal ganglia. Clin. Exp. Pharmacol. Physiol. 2007, 34, 528-532.
    • (2007) Clin. Exp. Pharmacol. Physiol , vol.34 , pp. 528-532
    • Curtis, M.A.1    Eriksson, P.S.2    Faull, R.L.M.3
  • 106
    • 17044375442 scopus 로고    scopus 로고
    • The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain
    • Curtis, M.A.; Penney, E.B.; Pearson, J.; Dragunow, M.; Connor, B.; Faull, R.L.M. The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain. Neuroscience 2005, 132, 777-788.
    • (2005) Neuroscience , vol.132 , pp. 777-788
    • Curtis, M.A.1    Penney, E.B.2    Pearson, J.3    Dragunow, M.4    Connor, B.5    Faull, R.L.M.6
  • 107
    • 0028596086 scopus 로고
    • In vitro neuronal productiondifferentiation by precursor cells derived from the adult human forebrain
    • Kirschenbaum, B.; Nedergaard, M.; Preuss, A.; Barami, K.; Fraser, R.A.; Goldman, S.A. In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cereb. Cortex 1994, 4, 576-589.
    • (1994) Cereb. Cortex , vol.4 , pp. 576-589
    • Kirschenbaum, B.1    Nedergaard, M.2    Preuss, A.3    Barami, K.4    Fraser, R.A.5    Goldman, S.A.6
  • 112
    • 0030979469 scopus 로고    scopus 로고
    • ellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
    • Doetsch, F.; Garcia-Verdugo, J.M.; Alvarez-Buylla, A. Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci. 1997, 17, 5046-5061.
    • (1997) J. Neurosci , vol.17 , pp. 5046-5061
    • Doetsch, F.1    Garcia-Verdugo, J.M.2    Alvarez-Buylla, A.3
  • 113
  • 117
    • 60649105513 scopus 로고    scopus 로고
    • The cellular composition and morphological organization of the rostral migratory stream in the adult human brain
    • Kam, M.; Curtis, M.A.; McGlashan, S.R.; Connor, B.; Nannmark, U.; Faull, R.L. The cellular composition and morphological organization of the rostral migratory stream in the adult human brain. J. Chem. Neuroanat. 2009, 37, 196-205.
    • (2009) J. Chem. Neuroanat , vol.37 , pp. 196-205
    • Kam, M.1    Curtis, M.A.2    McGlashan, S.R.3    Connor, B.4    Nannmark, U.5    Faull, R.L.6
  • 124
    • 84871953461 scopus 로고    scopus 로고
    • Relationship of glioblastoma multiforme to the subventricular zone is associated with survival
    • Jafri, N.F.; Clarke, J.L.; Weinberg, V.; Barani, I.J.; Cha, S. Relationship of glioblastoma multiforme to the subventricular zone is associated with survival. Neuroncology 2013, 15, 91-96.
    • (2013) Neuroncology , vol.15 , pp. 91-96
    • Jafri, N.F.1    Clarke, J.L.2    Weinberg, V.3    Barani, I.J.4    Cha, S.5
  • 130
    • 77954667472 scopus 로고    scopus 로고
    • Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma
    • Evers, P.; Lee, P.P.; Demarco, J.; Agazaryan, N.; Sayre, J.W.; Selch, M.; Pajonk, F. Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma. BMC Cancer 2010, 10, e384.
    • (2010) BMC Cancer , vol.e384 , pp. 10
    • Evers, P.1    Lee, P.P.2    Demarco, J.3    Agazaryan, N.4    Sayre, J.W.5    Selch, M.6    Pajonk, F.7
  • 131
    • 84864287761 scopus 로고    scopus 로고
    • Can irradiation of potential cancer stem-cell niche in the subventricular zone influence survival in patients with newly diagnosed glioblastoma
    • Gupta, T.; Nair, V.; Paul, S.N.; Kannan, S.; Moiyadi, A.; Epari, S.; Jalali, R. Can irradiation of potential cancer stem-cell niche in the subventricular zone influence survival in patients with newly diagnosed glioblastoma? J. Neurooncol. 2012, 109, 195-203.
    • (2012) J. Neurooncol , vol.109 , pp. 195-203
    • Gupta, T.1    Nair, V.2    Paul, S.N.3    Kannan, S.4    Moiyadi, A.5    Epari, S.6    Jalali, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.