Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generation

Cancer Research

Volumn 73, Issue 16, 2013, Pages 5232-5241

  Rawal, Malvika ^a   Schroeder, Samuel R ^a   Wagner, Brett A ^a   Cushing, Cameron M ^a   Welsh, Jessemae L ^b   Button, Anna M ^c   Du, Juan ^a   Sibenaller, Zita A ^a   Buettner, Garry R ^a,c   Cullen, Joseph J ^a,b,c,d  

^a Radiation Oncology   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CATALASE; HYDROGEN PEROXIDE; MANGANESE MESOTETRAKIS(N ETHYLPYRIDINIUM 2 YL)PORPHYRIN PENTACHLORIDE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN CHLORIDE; MANGANESE TETRAKIS(N METHYLPYRIDINIUM 4 YL)PORPHYRIN PENTACHLORIDE; OXYGEN; PORPHYRIN DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PANCREAS CANCER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STEADY STATE; THERMODYNAMICS;

EID: 84882637683     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0470     Document Type: Article

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