Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models

Free Radical Biology and Medicine

Volumn 51, Issue 3, 2011, Pages 681-687

  Chen, Ping ^a,b,c   Stone, Jennifer ^a   Sullivan, Garrett ^a   Drisko, Jeanne A ^a   Chen, Qi ^a,b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Ascorbic acid (ascorbate); Cancer; Free radicals; Glutathione; Hydrogen peroxide; Vitamin C

Indexed keywords

ASCORBIC ACID; GLUTATHIONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CYTOTOXICITY; DRUG ANTAGONISM; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ANTIOXIDANTS; ASCORBIC ACID; CARCINOMA; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; FEMALE; GLUTATHIONE; HELA CELLS; HUMANS; INFUSIONS, PARENTERAL; INJECTIONS, INTRAVENOUS; MICE; MICE, NUDE; PANCREATIC NEOPLASMS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79960008207     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.05.031     Document Type: Article

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