Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABA A-benzodiazepine receptors

Journal of Ethnopharmacology

Volumn 142, Issue 1, 2012, Pages 213-220

  Shrestha, Sabina ^a   Park, Ji Hae ^a   Lee, Dae Young ^a   Cho, Jin Gyeong ^a   Cho, Suengmok ^b   Yang, Hye Jin ^b   Yong, Hye Im ^b   Yoon, Min Seok ^b   Han, Dae Seok ^b   Baek, Nam In ^a  

^a Kyung Hee University   (South Korea)

^b Korea Food Research Institute   (South Korea)

Author keywords

Ayurveda; Biflavonoid; GABA type A benzodiazeine receptor; Hypnotic effects; Rhusflavone Rhus parviflora

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ACETIC ACID ETHYL ESTER; AGATHISFLAVONE; BENZODIAZEPINE RECEPTOR; BIFLAVONOID; BUTANOL; CUPRESSUFLAVONE; FLUMAZENIL; HYPNOTIC SEDATIVE AGENT; MESUAFERRONE B; METHANOL; PENTOBARBITAL; PLANT EXTRACT; RHUS PARVIFLORA METHANOL EXTRACT; RHUSFLAVANONE; RHUSFLAVONE; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ARTICLE; AYURVEDA; BINDING AFFINITY; BINDING SITE; DRUG STRUCTURE; FRUIT; INFRARED RADIATION; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; POISON IVY; RAT; RHUS PARVIFLORA; SLEEP; SLEEP INDUCTION; SOLVENT EXTRACTION;

ANIMALS; BIFLAVONOIDS; FRUIT; HYPNOTICS AND SEDATIVES; MALE; MICE; MICE, INBRED ICR; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RHUS; SLEEP;

MUS; RHUS PARVIFLORA;

EID: 84861983177     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.04.047     Document Type: Article

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