Innovations in proteomic profiling of cancers: Alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology

Journal of Proteomics

Volumn 90, Issue , 2013, Pages 28-37

  Omenn, Gilbert S ^a,c   Menon, Rajasree ^a   Zhang, Yang ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

Author keywords

Cancer biomarkers; Computational modeling; Differential expression; Splicing

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ANNEXIN; BIOLOGICAL MARKER; MESSENGER RNA; ISOPROTEIN; RNA; TUMOR MARKER; TUMOR PROTEIN;

ALGORITHM; ALTERNATIVE RNA SPLICING; BREAST CANCER; COLON CANCER; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EVOLUTION; EXON; GENETIC DATABASE; HUMAN; INTRON; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; NEOPLASM; NONHUMAN; PANCREAS ADENOCARCINOMA; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN TARGETING; PROTEOMICS; REVIEW; RNA TRANSCRIPTION; RNA TRANSLATION; SIGNAL TRANSDUCTION; SIMULATION; STRUCTURAL HOMOLOGY; STRUCTURAL PROTEOMICS; TISSUES; UPREGULATION; ZINC FINGER MOTIF; ANIMAL; BIOSYNTHESIS; CHEMISTRY; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; PROTEIN TERTIARY STRUCTURE;

ALTERNATIVE SPLICING; ANIMALS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; NEOPLASMS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; RNA, MESSENGER; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL;

EID: 84882604044     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2013.04.007     Document Type: Review

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