-
1
-
-
4143051237
-
Inhibition of centrosome separation after DNA damage: A role for Nek2
-
DOI 10.1667/RR3211
-
Fletcher L, Cerniglia GJ, Nigg EA, Yend TJ and Muschel RJ: Inhibition of centrosome separation after DNA damage: a role for Nek2. Radiat Res 162: 128-135, 2004. (Pubitemid 39100011)
-
(2004)
Radiation Research
, vol.162
, Issue.2
, pp. 128-135
-
-
Fletcher, L.1
Cerniglia, G.J.2
Nigg, E.A.3
Yen, T.J.4
Muschel, R.J.5
-
2
-
-
0037048312
-
The Nek2 protein kinase: A novel regulator of centrosome structure
-
Fry AM: The Nek2 protein kinase: a novel regulator of centrosome structure. Oncogene 21: 6184-6194, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 6184-6194
-
-
Fry, A.M.1
-
3
-
-
0038739131
-
Never say never. The NIMA-related protein kinases in mitotic control
-
DOI 10.1016/S0962-8924(03)00056-4
-
O'Connell MJ, Krien MJ and Hunter T: Never say never. The NIMA-related protein kinases in mitotic control. Trends Cell Biol 13: 221-228, 2003. (Pubitemid 36556006)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.5
, pp. 221-228
-
-
O'Connell, M.J.1
Krien, M.J.E.2
Hunter, T.3
-
4
-
-
0032518798
-
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
-
DOI 10.1093/emboj/17.2.470
-
Fry AM, Meraldi P and Nigg EA: A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J 17: 470-481, 1998. (Pubitemid 28045488)
-
(1998)
EMBO Journal
, vol.17
, Issue.2
, pp. 470-481
-
-
Fry, A.M.1
Meraldi, P.2
Nigg, E.A.3
-
5
-
-
40349089148
-
Analysis of the cellular centrosome in fine-needle aspirations of the breast
-
Guo HQ, Gao M, Ma J, Xiao T, Zhao LL, Gao Y and Pan QJ: Analysis of the cellular centrosome in fine-needle aspirations of the breast. Breast Cancer Res 9: R48, 2007.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Guo, H.Q.1
Gao, M.2
Ma, J.3
Xiao, T.4
Zhao, L.L.5
Gao, Y.6
Pan, Q.J.7
-
6
-
-
0032539868
-
Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity
-
DOI 10.1073/pnas.95.6.2950
-
Lingle WL, Lutz WH, Ingle JN, Maihle NJ and Salisbury JL: Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity. Proc Natl Acad Sci USA 95: 2950-2955, 1998. (Pubitemid 28135835)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.6
, pp. 2950-2955
-
-
Lingle, W.L.1
Lutz, W.H.2
Ingle, J.N.3
Maihle, N.J.4
Salisbury, J.L.5
-
7
-
-
77950627939
-
Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: A mechanism for aneuploidy in cancer
-
Liu Q, Hirohashi Y, Du X, Greene MI and Wang Q: Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer. Exp Mol Pathol 88: 225-233, 2010.
-
(2010)
Exp Mol Pathol
, vol.88
, pp. 225-233
-
-
Liu, Q.1
Hirohashi, Y.2
Du, X.3
Greene, M.I.4
Wang, Q.5
-
8
-
-
33646839443
-
Nek2 kinase in chromosome instability and cancer
-
DOI 10.1016/j.canlet.2005.06.017, PII S0304383505005616
-
Hayward DG and Fry AM: Nek2 kinase in chromosome instability and cancer. Cancer Lett 237: 155-166, 2006. (Pubitemid 43777084)
-
(2006)
Cancer Letters
, vol.237
, Issue.2
, pp. 155-166
-
-
Hayward, D.G.1
Fry, A.M.2
-
9
-
-
5644280152
-
The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer
-
DOI 10.1158/0008-5472.CAN-04-0960
-
Hayward DG, Clarke RB, Faragher AJ, Pillai MR, Hagan IM and Fry AM: The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer. Cancer Res 64: 7370-7376, 2004. (Pubitemid 39372076)
-
(2004)
Cancer Research
, vol.64
, Issue.20
, pp. 7370-7376
-
-
Hayward, D.G.1
Clarke, R.B.2
Faragher, A.J.3
Pillai, M.R.4
Hagan, I.M.5
Fry, A.M.6
-
10
-
-
0037324949
-
Gene expression profile of serial samples of transformed B-cell lymphomas
-
de Vos S, Hofmann WK, Grogan TM, et al: Gene expression profile of serial samples of transformed B-cell lymphomas. Lab Invest 83: 271-285, 2003. (Pubitemid 36255371)
-
(2003)
Laboratory Investigation
, vol.83
, Issue.2
, pp. 271-285
-
-
De Vos, S.1
Hofmann, W.-K.2
Grogan, T.M.3
Krug, U.4
Schrage, M.5
Miller, T.P.6
Braun, J.G.7
Wachsman, W.8
Koeffler, H.P.9
Said, J.W.10
-
11
-
-
0033560918
-
Two structural variants of Nek2 kinase, termed Nek2A and Nek2B, are differentially expressed in Xenopus tissues and development
-
DOI 10.1006/dbio.1999.9231
-
Uto K, Nakajo N and Sagata N: Two structural variants of Nek2 kinase, termed Nek2A and Nek2B, are differentially expressed in Xenopus tissues and development. Dev Biol 208: 456-464, 1999. (Pubitemid 29184003)
-
(1999)
Developmental Biology
, vol.208
, Issue.2
, pp. 456-464
-
-
Uto, K.1
Nakajo, N.2
Sagata, N.3
-
12
-
-
15044349834
-
Alternatively spliced protein variants as potential therapeutic targets for male infertility and contraception
-
DOI 10.1196/annals.1329.059
-
Fardilha M, Wu W, Sa R, et al: Alternatively spliced protein variants as potential therapeutic targets for male infertility and contraception. Ann NY Acad Sci 1030: 468-478, 2004. (Pubitemid 40378948)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1030
, pp. 468-478
-
-
Fardilha, M.1
Wu, W.2
Sa, R.3
Fidalgo, S.4
Sousa, C.5
Mota, C.6
Da, C.E.S.O.A.B.7
Da C.E, S.E.F.8
-
13
-
-
33645229443
-
High-resolution mapping of molecular events associated with immortalization, transformation, and progression to breast cancer in the MCF10 model
-
Worsham MJ, Pals G, Schouten JP, Miller F, Tiwari N, van Spaendonk R and Wolman SR: High-resolution mapping of molecular events associated with immortalization, transformation, and progression to breast cancer in the MCF10 model. Breast Cancer Res Treat 96: 177-186, 2006.
-
(2006)
Breast Cancer Res Treat
, vol.96
, pp. 177-186
-
-
Worsham, M.J.1
Pals, G.2
Schouten, J.P.3
Miller, F.4
Tiwari, N.5
Van Spaendonk, R.6
Wolman, S.R.7
-
14
-
-
38549147538
-
Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells
-
DOI 10.1111/j.1365-2184.2007.00498.x
-
Vazquez-Martin A, Colomer R, Brunet J, Lupu R and Menendez JA: Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells. Cell Prolif 41: 59-85, 2008. (Pubitemid 351147647)
-
(2008)
Cell Proliferation
, vol.41
, Issue.1
, pp. 59-85
-
-
Vazquez-Martin, A.1
Colomer, R.2
Brunet, J.3
Lupu, R.4
Menendez, J.A.5
-
15
-
-
34548857062
-
Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase
-
DOI 10.1074/jbc.M704969200
-
Wu W, Baxter JE, Wattam SL, et al: Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase. J Biol Chem 282: 26431-26440, 2007. (Pubitemid 47443796)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.36
, pp. 26431-26440
-
-
Wu, W.1
Baxter, J.E.2
Wattam, S.L.3
Hayward, D.G.4
Fardilha, M.5
Knebel, A.6
Ford, E.M.7
Da C. E S., E.F.8
Fry, A.M.9
-
16
-
-
84859569810
-
Nek2A contributes to tumorigenic growth and possibly functions as potential therapeutic target for human breast cancer
-
Wang S, Li W, Liu N, et al: Nek2A contributes to tumorigenic growth and possibly functions as potential therapeutic target for human breast cancer. J Cell Biochem 113: 1904-1914, 2012.
-
(2012)
J Cell Biochem
, vol.113
, pp. 1904-1914
-
-
Wang, S.1
Li, W.2
Liu, N.3
-
17
-
-
24944450362
-
The transcriptional repressor Snail promotes mammary tumor recurrence
-
DOI 10.1016/j.ccr.2005.07.009, PII S153561080500231X
-
Moody SE, Perez D, Pan TC, et al: The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 8: 197-209, 2005. (Pubitemid 41317591)
-
(2005)
Cancer Cell
, vol.8
, Issue.3
, pp. 197-209
-
-
Moody, S.E.1
Perez, D.2
Pan, T.-C.3
Sarkisian, C.J.4
Portocarrero, C.P.5
Sterner, C.J.6
Notorfrancesco, K.L.7
Cardiff, R.D.8
Chodosh, L.A.9
-
18
-
-
0035126052
-
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
-
DOI 10.1038/84691
-
D'Cruz CM, Gunther EJ, Boxer RB, et al: c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med 7: 235-239, 2001. (Pubitemid 32148492)
-
(2001)
Nature Medicine
, vol.7
, Issue.2
, pp. 235-239
-
-
D'Cruz, C.M.1
Gunther, E.J.2
Boxer, R.B.3
Hartman, J.L.4
Sintasath, L.5
Moody, S.E.6
Cox, J.D.7
Ha, S.I.8
Belka, G.K.9
Golant, A.10
Cardiff, R.D.11
Chodosh, L.A.12
-
19
-
-
0037442760
-
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
-
DOI 10.1101/gad.1051603
-
Gunther EJ, Moody SE, Belka GK, et al: Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev 17: 488-501, 2003. (Pubitemid 36258763)
-
(2003)
Genes and Development
, vol.17
, Issue.4
, pp. 488-501
-
-
Gunther, E.J.1
Moody, S.E.2
Belka, G.K.3
Hahn, K.T.4
Innocent, N.5
Dugan, K.D.6
Cardiff, R.D.7
Chodosh, L.A.8
-
20
-
-
24944516000
-
RNA interference and potential therapeutic applications of short interfering RNAs
-
Karagiannis TC and El- Osta A: RNA interference and potential therapeutic applications of short interfering RNAs. Cancer Gene Ther 12: 787-795, 2005.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 787-795
-
-
Karagiannis, T.C.1
El-Osta, A.2
-
21
-
-
25144498128
-
In vivo application of RNA interference: From functional genomics to therapeutics
-
Lu PY, Xie F and Woodle MC: In vivo application of RNA interference: from functional genomics to therapeutics. Adv Gen 54: 117-142, 2005.
-
(2005)
Adv Gen
, vol.54
, pp. 117-142
-
-
Lu, P.Y.1
Xie, F.2
Woodle, M.C.3
-
23
-
-
20444422912
-
Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B
-
Fletcher L, Cerniglia GJ, Yen TJ and Muschel RJ: Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B. Biochem Biophys Acta 1744: 89-92, 2005.
-
(2005)
Biochem Biophys Acta
, vol.1744
, pp. 89-92
-
-
Fletcher, L.1
Cerniglia, G.J.2
Yen, T.J.3
Muschel, R.J.4
-
24
-
-
2442504702
-
NEK2A Interacts with MAD1 and Possibly Functions as a Novel Integrator of the Spindle Checkpoint Signaling
-
DOI 10.1074/jbc.M314205200
-
Lou Y, Yao J, Zereshki A, et al: NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling. J Biol Chem 279: 20049-20057, 2004. (Pubitemid 38623449)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 20049-20057
-
-
Lou, Y.1
Yao, J.2
Zereshki, A.3
Dou, Z.4
Ahmed, K.5
Wang, H.6
Hu, J.7
Wang, Y.8
Yao, X.9
-
25
-
-
4544283606
-
Nek2A kinase regulates the localization of numatrin to centrosome in mitosis
-
DOI 10.1016/j.febslet.2004.08.047, PII S0014579304010658
-
Yao J, Fu C, Ding X, et al : Nek2A kinase regulates the localization of numatrin to centrosome in mitosis. FEBS Lett 575: 112-118, 2004. (Pubitemid 39237691)
-
(2004)
FEBS Letters
, vol.575
, Issue.1-3
, pp. 112-118
-
-
Yao, J.1
Fu, C.2
Ding, X.3
Guo, Z.4
Zenreski, A.5
Chen, Y.6
Ahmed, K.7
Liao, J.8
Dou, Z.9
Yao, X.10
-
26
-
-
58149284063
-
Nek2 as a novel molecular target for the treatment of breast carcinoma
-
Tsunoda N, Kokuryo T, Oda K, et al: Nek2 as a novel molecular target for the treatment of breast carcinoma. Cancer Sci 100: 111-116, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 111-116
-
-
Tsunoda, N.1
Kokuryo, T.2
Oda, K.3
-
27
-
-
59149104834
-
Insights into the conformational variability and regulation of human Nek2 kinase
-
Westwood I, Cheary DM, Baxter JE, Richards MW, van Montfort RL, Fry AM and Bayliss R: Insights into the conformational variability and regulation of human Nek2 kinase. J Mol Biol 386: 476-485, 2009.
-
(2009)
J Mol Biol
, vol.386
, pp. 476-485
-
-
Westwood, I.1
Cheary, D.M.2
Baxter, J.E.3
Richards, M.W.4
Van Montfort, R.L.5
Fry, A.M.6
Bayliss, R.7
|