IKK interacts with rictor and regulates mTORC2

Cellular Signalling

Volumn 25, Issue 11, 2013, Pages 2239-2245

  Xu, Yuanfei ^a   Lai, Eryong ^b   Liu, Jun ^c,d   Lin, Jun ^a   Yang, Cuilan ^a   Jia, Chunhong ^a   Li, Yunfeng ^b   Bai, Xiaochun ^a   Li, Ming ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

^d Guangzhou General Pharmaceutical Research Institute   (China)

Author keywords

Rictor; The I B kinase; The mammalian target of rapamycin complex 2

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; RICTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

RICTOR; THE IΚB KINASE; THE MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2;

ACTIN CYTOSKELETON; ANIMALS; CARRIER PROTEINS; CELL CYCLE; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; MICE; MULTIPROTEIN COMPLEXES; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84882584665     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.07.008     Document Type: Article

References (28)

1. Wullschleger S., Loewith R., Hall M.N. Cell 2006, 124:471.
2. Dunlop E.A., Tee A.R. Cell. Signal. 2009, 21:827.
3. Sabatini D.M. Nat. Rev. Cancer 2006, 6:729.
4. Kim D.H., Sarbassov D.D., Ali S.M., King J.E., Latek R.R., Erdjument-Bromage H., Tempst P., Sabatini D.M. Cell 2002, 110:163.
5. Dann S.G., Selvaraj A., Thomas G. Trends Mol. Med. 2007, 13:252.
6. Sarbassov D.D., Ali S.M., Kim D.H., Guertin D.A., Latek R.R., Erdjument-Bromage H., Tempst P., Sabatini D.M. Curr. Biol. 2004, 14:1296.
7. Sarbassov D.D., Guertin D.A., Ali S.M., Sabatini D.M. Science 2005, 307:1098.
8. Jacinto E., Facchinetti V., Liu D., Soto N., Wei S., Jung S.Y., Huang Q., Qin J., Su B. Cell 2006, 127:125.
9. Pearce L.R., Huang X., Boudeau J., Pawłowski R., Wullschleger S., Deak M., Ibrahim A.F., Gourlay R., Magnuson M.A., Alessi D.R. Biochem. J. 2007, 405:513.
10. Bhaskar P.T., Hay N. Dev. Cell 2007, 12:487.
11. Won J.H., Estela J. Cell Cycle 2010, 14:2305.
12. Nana Hagan G., Yenshou L., Mark A., Magnuson A. Mol. Cell. Biol. 2008, 28:4215.
13. Jacinto E., Loewith R., Schmidt A., Lin S., Ruegg M.A., Hall A., Hall M.N. Nat. Cell Biol. 2004, 6:1122.
14. Ivette H.N., Jorge C.O., Hans R., Ricardo H.G., Victor C.S.J., Guadalupe R.C., Silvio G.J., Jose V.P. J. Biol. Chem. 2007, 282:23708.
15. Li H., Lin X. Cytokine 2008, 41:1.
16. Hacker H., Karin M. Sci. STKE 2006, 357:re13.
17. Karin M. Oncogene 1999, 18:6867.
18. Ozes O.N., Akca H., Mayo L.D., Gustin J.A., Maehama T., Dixon J.E., Donner D.B. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:4640.
19. Lee D.F., Kuo H.P., Chen C.T., Hsu J.M., Chou C.K., Wei Y., Sun H.L., Li L.Y., Ping B., Huang W.C., He X., Hung J.Y., Lai C.C., Ding Q., Su J.L., Yang J.Y., Sahin A.A., Hortobagyi G.N., Tsai F.J., Tsai C.H., Hung M.C. Cell 2007, 130:440.
20. Dan H.C., Baldwin A.S. J. Immunol. 2008, 180:7582.
21. Dan H.C., Adli M., Baldwin A.S. Cancer Res. 2007, 67:263.
22. Julien L.A., Carriere A., Moreau J., Roux P.P. Mol. Cell. Biol. 2010, 30:908.
23. Copp J., Manning G., Hunter T. Cancer Res. 2009, 69:1821.
24. Chiang G.G., Abraham R.T. J. Biol. Chem. 2005, 280:25485.
25. Gan X., Wang J., Su B., Wu D. J. Biol. Chem. 2011, 286:10998.
26. Oh W.J., Wu C.C., Kim S.J., Facchinetti V., Julien L.A., Finlan M., Roux P.P., Su B., Jacinto E. EMBO J. 2010, 29:3939.
27. Zinzalla V., Stracka D., Oppliger W., Hall M.N. Cell 2011, 144:757.
28. Han C.D., Matthew J. Genes Dev. 2008, 22:1490.