Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 33, 2013, Pages

  Chen, Yen Shan ^a   Racca, Joseph D ^a   Sequeira, Paul W ^a   Phillips, Nelson B ^a   Weiss, Michael A ^a,b,c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b Case Western Reserve University   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Nucleocytoplasmic trafficking; Protein DNA recognition; Sexual dimorphism; Transcriptional activation; Triplet expansion

Indexed keywords

GLUTAMINE; HIGH MOBILITY GROUP PROTEIN; KRUPPEL LIKE FACTOR; MICROSATELLITE DNA; TRANSCRIPTION FACTOR SOX9; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CAG REPEAT; CELL DIFFERENTIATION; CLONAL EVOLUTION; CONTROLLED STUDY; DNA BINDING; DNA REPLICATION; GENE DELETION; GENE DUPLICATION; GENE TARGETING; HIGH MOBILITY GROUP BOX DOMAIN; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SERTOLI CELL; SEX DETERMINATION; SRY GENE; Y CHROMOSOME;

NUCLEOCYTOPLASMIC TRAFFICKING; PROTEIN-DNA RECOGNITION; SEXUAL DIMORPHISM; TRANSCRIPTIONAL ACTIVATION; TRIPLET EXPANSION;

ANIMALS; BIOLOGICAL EVOLUTION; BLOTTING, WESTERN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CIRCULAR DICHROISM; DNA; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HMG-BOX DOMAINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICROSATELLITE REPEATS; PROTEIN STRUCTURE, TERTIARY; RATS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RODENTIA; SEX DETERMINATION PROCESSES; SEX-DETERMINING REGION Y PROTEIN; SPECTROMETRY, FLUORESCENCE; TRINUCLEOTIDE REPEATS;

EID: 84882306712     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1300860110     Document Type: Article

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