Sry expression level and protein isoform differences play a role in abnormal testis development in C57BL/6J mice carrying certain Sry alleles

Genetics

Volumn 164, Issue 1, 2003, Pages 277-288

  Albrecht, Kenneth H ^a   Young, Maureen ^c   Washburn, Linda L ^c   Eicher, Eva M ^b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JACKSON LABORATORY   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; FETUS DEVELOPMENT; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GONAD DEVELOPMENT; HYBRID; KARYOTYPE 46,XX; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OVARY DEVELOPMENT; PRIORITY JOURNAL; SEX TRANSFORMATION; SEXUAL DEVELOPMENT; SRY GENE; TESTIS DEVELOPMENT; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE; Y CHROMOSOME;

ANIMALS; DNA-BINDING PROTEINS; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR PROTEINS; PROTEIN ISOFORMS; RNA, MESSENGER; SEX DETERMINATION (GENETICS); SEX-DETERMINING REGION Y PROTEIN; TESTIS; TRANSCRIPTION FACTORS; X CHROMOSOME; Y CHROMOSOME;

ANIMALIA; MAMMALIA; MUS; MUS MUSCULUS; MUS MUSCULUS DOMESTICUS; MUSCULUS;

EID: 0037854446     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. POS sex reversal and defines the SRY functional unit. Genetics 147: 1267-1277.
2. BARNES, J. D., J. L. CROSBY, C. M. JONES, C. V. WRIGHT and B. L. HOGAN, 1994 Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis. Dev. Biol. 161: 168-178.
3. BERGSTROM, D. E., M. YOUNG, K. H. ALBRECHT and E. M. EICHER, 2000 Related function of mouse SOX3, SOX9, and SRY HMG domains assayed by male sex determination. Genesis 28:111-124.
4. BIDDLE, F. G., and Y. NISHIOKA, 1988 Assays of testis development of the mouse distinguish three classes of domesticus-type Y chromosome. Genome 30: 870-878.
5. BISHOP, C. E., P. BOURSOT, B. BARON, F. BONHOMME and D. HATAT, 1985 Most classical Mus musculus domesticus laboratory mouse strains carry a Mus musculus musculus Y chromosome. Nature 315: 70-72.
6. BISHOP, C. E., A. WEITH, M. G. MATTEI and C. ROBERTS, 1988 Molecular aspects of sex determination in mice: an alternative model for the origin of the Sxr region. Philos. Trans. R. Soc. Lond. B Biol. Sci. 322: 119-124.
7. BONHOMME, F., 1986 Evolutionary relationships in the genus Mus. Curr. Top. Microbiol. Immunol. 127: 19-34.
8. CAPEL, B., K. H. ALBRECHT, L. L. WASHBURN and E. M. EICHER, 1999 Migration of mesonephric cells into the mammalian gonad depends on Sry. Mech. Dev, 84: 127-131.
9. CARLISLE, C., H. WINKING, D. WEICHENHAN and C. M. NAGAMINE, 1996 Absence of correlation between Sry polymorphisms and XY sex reversal caused by the M. m. domesticus Y chromosome. Genomics 33: 32-45.
10. CATTANACH, B. M., C. E. POLLARD and S. G. HAWKES, 1971 Sex-reversed mice: XX and XO males. Cytogenetics 10: 318-337.
11. CATTANACH, B. M., E. P. EVANS, M. D. BURTENSHAW and J. BARLOW, 1982 Male, female and intersex development in mice of identical chromosome constitution. Nature 300: 445-446.
12. DOM sex reversal. Nat. Genet. 6: 245-250.
13. EICHER, E. M., and L. L. WASHBURN, 1986 Genetic control of sex determination in mice. Annu. Rev. Genet. 20: 327-360.
14. POS mouse will develop as a female or as an hermaphrodite? J. Exp. Zool. 290: 322-326.
15. EICHER, E. M., W. G. BEAMER, L. L. WASHBURN and W. K. WHITTEN, 1980 A cytogenetic investigation of inherited true hermaphroditism in BALB/cWt mice. Cytogenet. Cell Genet. 28: 104-115.
16. EICHER, E. M., L. L. WASHBURN, J. B. WHITNEY, III and K. E. MORROW, 1982 Mus poschiavinus Y chromosome in the C57BL/6J murine genome causes sex reversal. Science 217: 535-537.
17. POS mice corrected by a Sry transgene. Philos. Trans. R. Soc. Lond. B Biol. Sci. 350: 263-269.
18. POS sex reversal. Nat. Genet. 14: 206-209.
19. EVANS, E. P., M. D. BURTENSHAW and B. M. CATTANACH, 1982 Meiotic crossing-over between the X and Y chromosomes of male mice carrying the sex-reversing (Sxr) factor. Nature 300: 443-445.
20. FUJII, T., J. G. PICHEL, M. TAIRA, R. TOYAMA, I. B. DAWID et al., 1994 Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system. Dev. Dyn. 199: 73-83.
21. GUBBAY, J., J. COLLIGNON, P. KOOPMAN, B. CAPEL, A. ECONOMOU et al., 1990 A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 346: 245-250.
22. GUBBAY, J., N. VIVIAN, A. ECONOMOU, D. JACKSON, P. GOODFELLOW et al., 1992 Inverted repeat structure of the Sry locus in mice. Proc. Natl. Acad. Sci. USA 89: 7953-7957.
23. HACKER, A., B. CAPEL, P. GOODFELLOW and R. LOVELL-BADGE, 1995 Expression of Sry, the mouse sex determining gene. Development 121: 1603-1614.
24. JESKE, Y. W., J. BOWLES, A. GREENFIELD and P. KOOPMAN, 1995 Expression of a linear Sry transcript in the mouse genital ridge. Nat. Genet. 10: 480-482.
25. KOOPMAN, P., J. GUBBAY, J. COLLIGNON and R. LOVELLBADGE, 1989 Zfy gene expression patterns are not compatible with a primary role in mouse sex determination. Nature 342: 940-942.
26. KOOPMAN, P., A. MÜNSTERBERG, B. CAPEL, N. VIVIAN and R. LOVELL-BADGE, 1990 Expression of a candidate sex-determining gene during mouse testis differentiation. Nature 348: 450-452.
27. KOOPMAN, P., J. GUBBAY, N. VIVIAN, P. GOODFELLOW and R. LOVELLBADGE, 1991 Male development of chromosomally female mice transgenic for Sry. Nature 352: 117-121.
28. DOM sex-reversal mouse gonad. Dev. Biol. 165: 442-452.
29. TIR sex reversal. Genesis 30: 7-11.
30. MCELREAVEY, K., and M. FELLOUS, 1999 Sex determination and the Y chromosome. Am. J. Med. Genet. 89: 176-185.
31. NAGAMINE, C. M., T. TAKETO and G. C. KOO, 1987 Studies on the genetics of tda-1 XY sex reversal in the mouse. Differentiation 33: 223-231.
32. NAGAMINE, C. M., K. MOROHASHI, C. CARLISLE and D. K. CHANG, 1999 Sex reversal caused by Mus musculus domesticus Y chromosomes linked to variant expression of the testis-determining gene Sry. Dev. Biol. 216: 182-194.
33. NISHIOKA, Y., and E. LAMOTHE, 1987 The Mus musculus musculus type Y chromosome predominates in Asian house mice. Genet. Res. 50: 195-198.
34. SCHAFER, A. J., 1995 Sex determination and its pathology in man. Adv. Genet. 33: 275-329.
35. SIMPSON, E., A. MCLAREN, P. CHANDLER and K. TOMONARI, 1984 Expression of H-Y antigen by female mice carrying Sxr. Transplantation 37: 17-21.
36. THEILER, K., 1989 The House Mouse. Springer-Verlag, New York.
37. TUCKER, P. K., B. K. LEE, B. L. LUNDRIGAN and E. M. EICHER, 1992 Geographic origin of the Y chromosome of "old" inbred strains of mice. Mamm. Genome 3: 254-261.
38. WAGNER, T. E., P. C. HOPPE, J. D. JOLLICK, D. R. SCHOLL, R. L. HODINKA et al., 1981 Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring. Proc. Natl. Acad. Sci. USA 78: 6376-6380.
39. WASHBURN, L. L., and E. M. EICHER, 1983 Sex reversal in XY mice caused by dominant mutation on chromosome 17. Nature 303: 338-340.
40. WASHBURN, L. L., and E. M. EICHER, 1989 Normal testis determination in the mouse depends on genetic interaction of a locus on chromosome 17 and the Y chromosome. Genetics 123: 173-179.
41. WASHBURN, L. L., K. H. ALBRECHT and E. M. EICHER, 2001 C57BL/6J-T-associated sex reversal in mice is caused by reduced expression of a Mus domesticus Sry allele. Genetics 158: 1675-1681.