Bioimaging and pulmonary applications of self-assembled Flt1 peptide-hyaluronic acid conjugate nanoparticles

Biomaterials

Volumn 34, Issue 33, 2013, Pages 8478-8490

  Kim, Hyemin ^a   Park, Hyun Taek ^a   Tae, You Me ^a   Kong, Won Ho ^a   Sung, Dong Kyung ^b   Hwang, Byung Woo ^a   Kim, Ki Su ^a   Kim, Yoon Keun ^a   Hahn, Sei Kwang ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Samsung Medical Center   (South Korea)

Author keywords

Asthma; Dexamethasone; Flt1 peptide; Hyaluronic acid; Nanoparticle; Pulmonary delivery

Indexed keywords

ASTHMA; DEXAMETHASONES; HISTOLOGICAL ANALYSIS; LUNG EPITHELIAL CELLS; MUCOADHESIVE PROPERTIES; PHOSPHONIUM HEXAFLUOROPHOSPHATE; PULMONARY DELIVERY; PULMONARY DRUG DELIVERY;

DISEASES; DRUG PRODUCTS; DYNAMIC LIGHT SCATTERING; HYALURONIC ACID; MAMMALS; MOLECULAR BIOLOGY; NANOPARTICLES; ORGANIC ACIDS; PATIENT REHABILITATION; PATIENT TREATMENT; TRANSMISSION ELECTRON MICROSCOPY;

PEPTIDES;

BENZOTRIAZOL 1 YLOXY TRIS(DIMETHYLAMINO)PHOSPHONIUMHEXA FLUOROPHOSPHATE; CORTICOSTEROID; DEXAMETHASONE; HYALURONIC ACID; LIPOPOLYSACCHARIDE; NANOPARTICLE; PYROPHOSPHORIC ACID DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CONJUGATE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ENDOCYTOSIS; EPITHELIUM CELL; HUMAN; IN VITRO STUDY; INTERNALIZATION; LIGHT SCATTERING; LUNG ALVEOLUS EPITHELIUM; LUNG LAVAGE; LUNG PARENCHYMA; MOLECULAR IMAGING; MOUSE; NONHUMAN; PRIORITY JOURNAL; THERAPY EFFECT; TISSUE SECTION; TRANSMISSION ELECTRON MICROSCOPY;

MUS;

ASTHMA; DEXAMETHASONE; FLT1 PEPTIDE; HYALURONIC ACID; NANOPARTICLE; PULMONARY DELIVERY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE, TUMOR; CELL PROLIFERATION; DEXAMETHASONE; DIAGNOSTIC IMAGING; HUMANS; HYALURONIC ACID; MICE; NANOPARTICLES;

EID: 84881664035     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.07.062     Document Type: Article

References (34)

1. Busse W.W., Lemanske R.F. Asthma. NEngl J Med 2001, 344:350-362.
2. Bochner B.S., Undem B.J., Lichtenstein L.M. Immunological aspects of allergic asthma. Annu Rev Immunol 1994, 12:295-335.
3. Cohn L., Elias J.A., Chupp G.L. Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol 2004, 22:789-815.
4. Cho S.H., Stanciu L.A., Holgate S.T., Johnston S.L. Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma. Am J Respir Crit Care Med 2005, 171:224-230.
5. National Heart, Lung, and Blood Institute Guidelines for the diagnosis and management of asthma (EPR-3) 2007, 214. Available from: URL:. http://www.nhlbi.nih.gov/guidelines/asthma/.
6. Dominique M.B., Els T., Liesbeth C., Ellen D., Peter W.H., Lieven J.D., et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?. Respir Res 2006, 7:135-139.
7. Bryan C.P., Alison L.B., Alan P.B., Matthew A.S., Nicholas W.L. Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology. Nat Med 2012, 18:751-758.
8. Kim Y.K., Oh S.Y., Jeon S.G., Park H.W., Lee S.Y., Chun E.Y., et al. Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma. JImmunol 2007, 178:5375-5382.
9. Kim Y.S., Hong S.W., Choi J.P., Shin T.S., Moon H.G., Choi E.J., et al. Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways. JImmunol 2009, 183:5113-5120.
10. Chetta A., Zanini A., Foresi A., Donno M.D., Castagnaro A., D'lppolito R., et al. Vascular component of airway remodeling in asthma is reduced by high dose of fluticasone. Am J Respir Crit Care Med 2003, 167:751-757.
11. Hashimoto M., Tanaka H., Abe S. Quantitative analysis of bronchial wall vascularity in the medium and small airways of patients with asthma and COPD. Chest 2005, 127:965-972.
12. Chetta A., Zanini A., Foresi A., D'lppolito R., Tipa A., Castagnaro A., et al. Vascular endothelial growth factor up-regulation and bronchial wall remodeling in asthma. Clin Exp Allergy 2005, 35:1437-1442.
13. Lee K.S., Min K.H., Kim S.R., Park S.J., Park H.S., Jin G.J., et al. Vascular endothelial growth factor modulates metalloproteinase-9 expression in asthma. Am J Respir Crit Care Med 2006, 174:161-170.
14. Bae D.G., Kim T.D., Li G., Yoon W.H., Chae C.B. Anti-Flt1 peptide, a vascular endothelial growth factor receptor 1-specific hexapeptide, inhibits tumor growth and metastasis. Clin Cancer Res 2005, 11:2651-2661.
15. Kim Y.S., Choi S.J., Tae Y.M., Lee B.J., Jeon S.G., Oh S.Y., et al. Distinct roles of vascular endothelial growth factor receptor-1- and receptor-2-mediated signaling in T cell priming and Th17 polarization to lipopolysaccharide-containing allergens in the lung. JImmunol 2010, 185:5648-5655.
16. Varghese O.P., Sun W., Hilborn J., Ossipov D.A. In situ cross-linkable high molecular weight hyaluronan-bisphosphonate conjugate for localized delivery and cell-specific targeting: a hydrogel linked prodrug approach. JAm Chem Soc 2009, 131:8781-8783.
17. Jiang D., Liang J., Fan J., Yu S., Chen S., Luo Y., et al. Regulation of lung injury and repair by toll-like receptors and hyaluronan. Nat Med 2005, 11:1173-1179.
18. Al-Qadi S., Grenha A., Remunan-Lopez C. Microspheres loaded with polysaccharide nanoparticles for pulmonary delivery: preparation, structure and surface analysis. Carbohydr Polym 2011, 86:25-34.
19. Surendrakumar K., Martyn G.P., Hodgers E.C.M., Jansen M., Blair J.A. Sustained release of insulin from sodium hyaluronate based dry powder formulations after pulmonary delivery to beagle dogs. JControl Release 2003, 91:385-394.
20. Alpar H.O., Somavarapu S., Atuah K.N., Bramwell V.W. Biodegradable mucoadhesive particulates for nasal and pulmonary antigen and DNA delivery. Adv Drug Deliv Rev 2005, 57:411-430.
21. Hanania N.A., Chapman K.R., Kesten S. Adverse effects of inhaled corticosteroids. Am J Med 1995, 98:196-208.
22. Ng P.C. The effectiveness and side effects of dexamethasone in preterm infants with bronchopulmonary dysplasia. Arch Dis Child 1993, 68:330-336.
23. Zhou B., Weigel J.A., Fauss L.A., Weigel P.H. Identification of the hyaluronan receptor for endocytosis. JBiol Chem 2000, 275:37733-37741.
24. Banerji S., Ni J., Wang S.X., Clasper S., Su J., Tammi R., et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. JCell Biol 1999, 144:789-801.
25. Holgate S.T., Lackie P.M., Davies D.E., Roche W.R., Walls A.F. The bronchial epithelium as a key regulator of airway inflammation and remodeling in asthma. Clin Exp Allergy 1999, 29:90-95.
26. Oh E.J., Kim J.W., Kong J.H., Ryu S.H., Hahn S.K. Signal transduction of hyaluronic acid-peptide conjugate for formyl peptide receptor like 1 receptor. Bioconjug Chem 2008, 19:2401-2408.
27. Oh E.J., Park K., Choi J.S., Joo C.K., Hahn S.K. Synthesis, characterization, and preliminary assessment of anti-Flt1 peptide - hyaluronate conjugate for the treatment of corneal neovascularization. Biomaterials 2009, 30:6026-6034.
28. Kim E.S., Chang Y.S., Choi S.J., Kim J.K., Yoo H.S., Ahn S.Y., et al. Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells attenuates Escherichia coli-induced acute lung injury in mice. Respir Res 2011, 12:108-118.
29. Jeon S.G., Moon H.G., Kim Y.S., Choi J.P., Shin T.S., Hong S.W., et al. 15-Lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA. Clin Exp Allergy 2009, 39:908-917.
30. Oh E.J., Choi J.S., Kim H., Joo C.K., Hahn S.K. Anti-Flt1 peptide-hyaluronate conjugate for the treatment of retinal neovascularization and diabetic retinopathy. Biomaterials 2011, 32:3115-3123.
31. Kim H., Choi J.S., Kim K.S., Yang J.A., Joo C.K., Hahn S.K. Flt1 peptide - hyaluronate conjugate micelle-like nanoparticles encapsulating genistein for the treatment of ocular neovascularization. Acta Biomater 2012, 8:3932-3940.
32. Breeuwer P., Drocourt J., Rombouts F.M., Abee T. Anovel method for continuous determination of the intracellular pH in bacteria with the internally conjugated fluorescent probe 5 (and 6-)-carboxyfluorescein succinimidyl ester. Appl Environ Microbiol 1996, 62:178-183.
33. Qhattal H.S.S., Liu X. Characterization of CD44-mediated cancer cell uptake and intracellular distribution of hyaluronan-grafted liposomes. Mol Pharm 2011, 8:1233-1246.
34. McKee C.M., Penno M.B., Cowman M., Burdick M.D., Strieter R.M., Bao C., et al. Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44. JClin Invest 1996, 98:2403-2413.