Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 305, Issue 4, 2013, Pages

  Schmidt, Tracy Thennes ^a   Tauseef, Mohammad ^a   Yue, Lili ^a   Bonini, Marcelo G ^a   Gothert, Joachim ^b   Shen, Tang Long ^c   Guan, Jun Lin ^c   Predescu, Sanda ^d   Sadikot, Ruxana ^a   Mehta, Dolly ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d RUSH UNIVERSITY   (United States)

Author keywords

Acute lung injury; Adherens junctions; Endothelial barrier; Focal adhesion kinase

Indexed keywords

FOCAL ADHESION KINASE; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; ENDOTHELIUM; LUNG BLOOD VESSEL; LUNG INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

ACUTE LUNG INJURY; ADHERENS JUNCTIONS; ENDOTHELIAL BARRIER; FOCAL ADHESION KINASE;

ANIMALS; BODY FLUIDS; ENDOTHELIAL CELLS; ENDOTHELIUM; ENZYME STABILITY; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE DELETION; HUMANS; INTEGRASES; LUNG; LUNG INJURY; MALE; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; ORGAN SPECIFICITY; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN;

EID: 84881644076     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00094.2013     Document Type: Article

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