-
1
-
-
77954216770
-
Molecular imaging and targeted therapies
-
Morse DL, Gillies RJ, (2010) Molecular imaging and targeted therapies. Biochem Pharmacol 80: 731-738.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 731-738
-
-
Morse, D.L.1
Gillies, R.J.2
-
3
-
-
0042763165
-
Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR
-
Ardenkjaer-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, et al. (2003) Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc Natl Acad Sci U S A 100: 10158-10163.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10158-10163
-
-
Ardenkjaer-Larsen, J.H.1
Fridlund, B.2
Gram, A.3
Hansson, G.4
Hansson, L.5
-
4
-
-
79951507755
-
Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research
-
Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev EY, Comment A, et al. (2011) Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia 13: 81-97.
-
(2011)
Neoplasia
, vol.13
, pp. 81-97
-
-
Kurhanewicz, J.1
Vigneron, D.B.2
Brindle, K.3
Chekmenev, E.Y.4
Comment, A.5
-
5
-
-
43949109568
-
Compressed sensing for resolution enhancement of hyperpolarized 13C flyback 3D-MRSI
-
Hu S, Lustig M, Chen AP, Crane J, Kerr A, et al. (2008) Compressed sensing for resolution enhancement of hyperpolarized 13C flyback 3D-MRSI. J Magn Reson 192: 258-264.
-
(2008)
J Magn Reson
, vol.192
, pp. 258-264
-
-
Hu, S.1
Lustig, M.2
Chen, A.P.3
Crane, J.4
Kerr, A.5
-
6
-
-
79951818706
-
Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies
-
Larson PE, Hu S, Lustig M, Kerr AB, Nelson SJ, et al. (2011) Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies. Magn Reson Med 65: 610-619.
-
(2011)
Magn Reson Med
, vol.65
, pp. 610-619
-
-
Larson, P.E.1
Hu, S.2
Lustig, M.3
Kerr, A.B.4
Nelson, S.J.5
-
7
-
-
84881585289
-
Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance spectroscopic imaging (MRSI)
-
In press
-
Ohliger MA, Larson PE, Bok RA, Shin P, Hu S, et al. (2013) Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance spectroscopic imaging (MRSI). J Magn Reson Imaging: In press.
-
(2013)
J Magn Reson Imaging
-
-
Ohliger, M.A.1
Larson, P.E.2
Bok, R.A.3
Shin, P.4
Hu, S.5
-
8
-
-
69449097368
-
Application of subsecond spiral chemical shift imaging to real-time multislice metabolic imaging of the rat in vivo after injection of hyperpolarized 13C1-pyruvate
-
Mayer D, Yen YF, Tropp J, Pfefferbaum A, Hurd RE, et al. (2009) Application of subsecond spiral chemical shift imaging to real-time multislice metabolic imaging of the rat in vivo after injection of hyperpolarized 13C1-pyruvate. Magn Reson Med 62: 557-564.
-
(2009)
Magn Reson Med
, vol.62
, pp. 557-564
-
-
Mayer, D.1
Yen, Y.F.2
Tropp, J.3
Pfefferbaum, A.4
Hurd, R.E.5
-
9
-
-
34547930743
-
Optimization of fast spiral chemical shift imaging using least squares reconstruction: application for hyperpolarized (13)C metabolic imaging
-
Levin YS, Mayer D, Yen YF, Hurd RE, Spielman DM, (2007) Optimization of fast spiral chemical shift imaging using least squares reconstruction: application for hyperpolarized (13)C metabolic imaging. Magn Reson Med 58: 245-252.
-
(2007)
Magn Reson Med
, vol.58
, pp. 245-252
-
-
Levin, Y.S.1
Mayer, D.2
Yen, Y.F.3
Hurd, R.E.4
Spielman, D.M.5
-
10
-
-
34447576611
-
Double spin-echo sequence for rapid spectroscopic imaging of hyperpolarized 13C
-
Cunningham CH, Chen AP, Albers MJ, Kurhanewicz J, Hurd RE, et al. (2007) Double spin-echo sequence for rapid spectroscopic imaging of hyperpolarized 13C. J Magn Reson 187: 357-362.
-
(2007)
J Magn Reson
, vol.187
, pp. 357-362
-
-
Cunningham, C.H.1
Chen, A.P.2
Albers, M.J.3
Kurhanewicz, J.4
Hurd, R.E.5
-
11
-
-
75749094342
-
3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer
-
Hu S, Lustig M, Balakrishnan A, Larson PE, Bok R, et al. (2010) 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer. Magn Reson Med 63: 312-321.
-
(2010)
Magn Reson Med
, vol.63
, pp. 312-321
-
-
Hu, S.1
Lustig, M.2
Balakrishnan, A.3
Larson, P.E.4
Bok, R.5
-
12
-
-
70649093026
-
Accelerated spectroscopic imaging of hyperpolarized C-13 pyruvate using SENSE parallel imaging
-
Arunachalam A, Whitt D, Fish K, Giaquinto R, Piel J, et al. (2009) Accelerated spectroscopic imaging of hyperpolarized C-13 pyruvate using SENSE parallel imaging. NMR Biomed 22: 867-873.
-
(2009)
NMR Biomed
, vol.22
, pp. 867-873
-
-
Arunachalam, A.1
Whitt, D.2
Fish, K.3
Giaquinto, R.4
Piel, J.5
-
13
-
-
77649134950
-
Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI
-
Larson PE, Bok R, Kerr AB, Lustig M, Hu S, et al. (2010) Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI. Magn Reson Med 63: 582-591.
-
(2010)
Magn Reson Med
, vol.63
, pp. 582-591
-
-
Larson, P.E.1
Bok, R.2
Kerr, A.B.3
Lustig, M.4
Hu, S.5
-
14
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB, (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
15
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ, (2004) Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
16
-
-
54249093810
-
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading
-
Albers MJ, Bok R, Chen AP, Cunningham CH, Zierhut ML, et al. (2008) Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. Cancer Res 68: 8607-8615.
-
(2008)
Cancer Res
, vol.68
, pp. 8607-8615
-
-
Albers, M.J.1
Bok, R.2
Chen, A.P.3
Cunningham, C.H.4
Zierhut, M.L.5
-
17
-
-
35948970970
-
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
-
Day SE, Kettunen MI, Gallagher FA, Hu DE, Lerche M, et al. (2007) Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med 13: 1382-1387.
-
(2007)
Nat Med
, vol.13
, pp. 1382-1387
-
-
Day, S.E.1
Kettunen, M.I.2
Gallagher, F.A.3
Hu, D.E.4
Lerche, M.5
-
18
-
-
84857227950
-
Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization
-
Bohndiek SE, Kettunen MI, Hu DE, Brindle KM, (2012) Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization. Cancer Res 72: 854-864.
-
(2012)
Cancer Res
, vol.72
, pp. 854-864
-
-
Bohndiek, S.E.1
Kettunen, M.I.2
Hu, D.E.3
Brindle, K.M.4
-
19
-
-
79958244879
-
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging
-
Park I, Bok R, Ozawa T, Phillips JJ, James CD, et al. (2011) Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging. J Magn Reson Imaging 33: 1284-1290.
-
(2011)
J Magn Reson Imaging
, vol.33
, pp. 1284-1290
-
-
Park, I.1
Bok, R.2
Ozawa, T.3
Phillips, J.J.4
James, C.D.5
-
20
-
-
79960113705
-
Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells
-
Witney TH, Kettunen MI, Brindle KM, (2011) Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells. J Biol Chem 286: 24572-24580.
-
(2011)
J Biol Chem
, vol.286
, pp. 24572-24580
-
-
Witney, T.H.1
Kettunen, M.I.2
Brindle, K.M.3
-
21
-
-
0014440379
-
Rate of isotope exchange in enzyme-catalyzed reactions
-
Yagil G, Hoberman HD, (1969) Rate of isotope exchange in enzyme-catalyzed reactions. Biochemistry 8: 352-360.
-
(1969)
Biochemistry
, vol.8
, pp. 352-360
-
-
Yagil, G.1
Hoberman, H.D.2
-
22
-
-
0000039143
-
Kinetic studies of rabbit muscle lactate dehydrogenase
-
Zewe V, Fromm HJ, (1962) Kinetic studies of rabbit muscle lactate dehydrogenase. J Biol Chem 237: 1668-1675.
-
(1962)
J Biol Chem
, vol.237
, pp. 1668-1675
-
-
Zewe, V.1
Fromm, H.J.2
-
23
-
-
0007285384
-
Kinetic Studies of Rabbit Muscle Lactate Dehydrogenase. Ii. Mechanism of the Reaction
-
Zewe V, Fromm HJ, (1965) Kinetic Studies of Rabbit Muscle Lactate Dehydrogenase. Ii. Mechanism of the Reaction. Biochemistry 4: 782-792.
-
(1965)
Biochemistry
, vol.4
, pp. 782-792
-
-
Zewe, V.1
Fromm, H.J.2
-
24
-
-
84860502652
-
Biochemical issues in estimation of cytosolic free NAD/NADH ratio
-
Sun F, Dai C, Xie J, Hu X, (2012) Biochemical issues in estimation of cytosolic free NAD/NADH ratio. PLoS One 7: e34525.
-
(2012)
PLoS One
, vol.7
-
-
Sun, F.1
Dai, C.2
Xie, J.3
Hu, X.4
-
25
-
-
70849085768
-
Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells
-
Harris T, Eliyahu G, Frydman L, Degani H, (2009) Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells. Proc Natl Acad Sci U S A 106: 18131-18136.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18131-18136
-
-
Harris, T.1
Eliyahu, G.2
Frydman, L.3
Degani, H.4
-
26
-
-
84868089158
-
Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13 C NMR
-
Harrison C, Yang C, Jindal A, DeBerardinis RJ, Hooshyar MA, et al. (2012) Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13 C NMR. NMR Biomed 25: 1286-1294.
-
(2012)
NMR Biomed
, vol.25
, pp. 1286-1294
-
-
Harrison, C.1
Yang, C.2
Jindal, A.3
DeBerardinis, R.J.4
Hooshyar, M.A.5
-
27
-
-
84885330774
-
Kinetic modeling of hyperpolarized (13) C pyruvate metabolism in tumors using a measured arterial input function
-
in press
-
Kazan SM, Reynolds S, Kennerley A, Wholey E, Bluff JE, et al. (2012) Kinetic modeling of hyperpolarized (13) C pyruvate metabolism in tumors using a measured arterial input function. Magn Reson Med: in press.
-
(2012)
Magn Reson Med
-
-
Kazan, S.M.1
Reynolds, S.2
Kennerley, A.3
Wholey, E.4
Bluff, J.E.5
-
29
-
-
76749161366
-
Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy
-
Ward CS, Venkatesh HS, Chaumeil MM, Brandes AH, Vancriekinge M, et al. (2010) Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy. Cancer Res 70: 1296-1305.
-
(2010)
Cancer Res
, vol.70
, pp. 1296-1305
-
-
Ward, C.S.1
Venkatesh, H.S.2
Chaumeil, M.M.3
Brandes, A.H.4
Vancriekinge, M.5
-
30
-
-
84862515692
-
Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation
-
Sandulache VC, Skinner HD, Wang Y, Chen Y, Dodge CT, et al. (2012) Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation. Mol Cancer Ther 11: 1373-1380.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1373-1380
-
-
Sandulache, V.C.1
Skinner, H.D.2
Wang, Y.3
Chen, Y.4
Dodge, C.T.5
-
31
-
-
0030308425
-
Gradient-echo imaging considerations for hyperpolarized 129Xe MR
-
Zhao L, Mulkern R, Tseng CH, Williamson D, Patz S, et al. (1996) Gradient-echo imaging considerations for hyperpolarized 129Xe MR. J Magn Reson B 113: 179-183.
-
(1996)
J Magn Reson B
, vol.113
, pp. 179-183
-
-
Zhao, L.1
Mulkern, R.2
Tseng, C.H.3
Williamson, D.4
Patz, S.5
-
32
-
-
84883225184
-
Detection of radiation-induced lung injury using hyperpolarized (13) C magnetic resonance spectroscopy and imaging
-
in press
-
Thind K, Chen A, Friesen-Waldner L, Ouriadov A, Scholl TJ, et al. (2012) Detection of radiation-induced lung injury using hyperpolarized (13) C magnetic resonance spectroscopy and imaging. Magn Reson Med: in press.
-
(2012)
Magn Reson Med
-
-
Thind, K.1
Chen, A.2
Friesen-Waldner, L.3
Ouriadov, A.4
Scholl, T.J.5
-
33
-
-
84873993074
-
Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells
-
Lodi A, Woods SM, Ronen SM, (2013) Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells. NMR Biomed 26: 299-306.
-
(2013)
NMR Biomed
, vol.26
, pp. 299-306
-
-
Lodi, A.1
Woods, S.M.2
Ronen, S.M.3
-
34
-
-
84865191464
-
Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis
-
Clatworthy MR, Kettunen MI, Hu DE, Mathews RJ, Witney TH, et al. (2012) Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis. Proc Natl Acad Sci U S A 109: 13374-13379.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13374-13379
-
-
Clatworthy, M.R.1
Kettunen, M.I.2
Hu, D.E.3
Mathews, R.J.4
Witney, T.H.5
-
35
-
-
78650472851
-
Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy
-
Bohndiek SE, Kettunen MI, Hu DE, Witney TH, Kennedy BW, et al. (2010) Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy. Mol Cancer Ther 9: 3278-3288.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 3278-3288
-
-
Bohndiek, S.E.1
Kettunen, M.I.2
Hu, D.E.3
Witney, T.H.4
Kennedy, B.W.5
-
36
-
-
84876494236
-
EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate
-
Matsumoto S, Saito K, Yasui H, Morris HD, Munasinghe JP, et al. (2013) EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate. Magn Reson Med 69: 1443-1450.
-
(2013)
Magn Reson Med
, vol.69
, pp. 1443-1450
-
-
Matsumoto, S.1
Saito, K.2
Yasui, H.3
Morris, H.D.4
Munasinghe, J.P.5
-
37
-
-
84875372304
-
Reproducibility study for free-breathing measurements of pyruvate metabolism using hyperpolarized (13) C in the heart
-
Lau AZ, Chen AP, Barry J, Graham JJ, Dominguez-Viqueira W, et al. (2013) Reproducibility study for free-breathing measurements of pyruvate metabolism using hyperpolarized (13) C in the heart. Magn Reson Med 69: 1063-1071.
-
(2013)
Magn Reson Med
, vol.69
, pp. 1063-1071
-
-
Lau, A.Z.1
Chen, A.P.2
Barry, J.3
Graham, J.J.4
Dominguez-Viqueira, W.5
-
39
-
-
84864349557
-
Fully MR-Compatible Syringe Pump for the Controllable Injection of Hyperpolarized Substrate in Animals
-
Reynolds S, Kazan S, Bluff J, Port M, Wholey E, et al. (2012) Fully MR-Compatible Syringe Pump for the Controllable Injection of Hyperpolarized Substrate in Animals. Applied Magnetic Resonance 43: 263-273.
-
(2012)
Applied Magnetic Resonance
, vol.43
, pp. 263-273
-
-
Reynolds, S.1
Kazan, S.2
Bluff, J.3
Port, M.4
Wholey, E.5
-
40
-
-
79956312010
-
Quantitative imaging test approval and biomarker qualification: interrelated but distinct activities
-
Buckler AJ, Bresolin L, Dunnick NR, Sullivan DC, Aerts HJ, et al. (2011) Quantitative imaging test approval and biomarker qualification: interrelated but distinct activities. Radiology 259: 875-884.
-
(2011)
Radiology
, vol.259
, pp. 875-884
-
-
Buckler, A.J.1
Bresolin, L.2
Dunnick, N.R.3
Sullivan, D.C.4
Aerts, H.J.5
-
41
-
-
84873428339
-
Assessment of early diabetic renal changes with hyperpolarized [1-(13) C]pyruvate
-
Laustsen C, Ostergaard JA, Lauritzen MH, Norregaard R, Bowen S, et al. (2013) Assessment of early diabetic renal changes with hyperpolarized [1-(13) C]pyruvate. Diabetes Metab Res Rev 29: 125-129.
-
(2013)
Diabetes Metab Res Rev
, vol.29
, pp. 125-129
-
-
Laustsen, C.1
Ostergaard, J.A.2
Lauritzen, M.H.3
Norregaard, R.4
Bowen, S.5
|