Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging

Journal of Magnetic Resonance Imaging

Volumn 33, Issue 6, 2011, Pages 1284-1290

  Park, Ilwoo ^a,c   Bok, Robert ^a   Ozawa, Tomoko ^a   Phillips, Joanna J ^a   James, C David ^a   Vigneron, Daniel B ^a,b   Ronen, Sabrina M ^a   Nelson, Sarah J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Francisco   (United States)

^c NONE   (United States)

Author keywords

brain tumor; dynamic nuclear polarization; hyperpolarized 13C MRSI; response to temozolomide

Indexed keywords

LACTIC ACID; PYRUVIC ACID; PYRUVIC ACID C 13; RADIOPHARMACEUTICAL AGENT; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DYNAMIC NUCLEAR POLARIZATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLARIZATION; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; TREATMENT RESPONSE; TUMOR CELL LINE; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; CARBON ISOTOPES; CELL LINE, TUMOR; DACARBAZINE; DRUG MONITORING; GLIOBLASTOMA; HUMANS; LACTIC ACID; MAGNETIC RESONANCE IMAGING; MALE; NEOPLASM TRANSPLANTATION; PYRUVIC ACID; RATS; TREATMENT OUTCOME;

EID: 79958244879     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22563     Document Type: Article

References (26)

1. Macdonald DR, Cascino TL, Schold SC Jr, Cairncross JG,. Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 1990; 8: 1277-1280. (Pubitemid 20195640)
2. Walecki J, Tarasow E, Kubas B, et al. Hydrogen-1 MR spectroscopy of the peritumoral zone in patients with cerebral glioma: assessment of the value of the method. Acad Radiol 2003; 10: 145-153. (Pubitemid 36150967)
3. Balmaceda C, Critchell D, Mao X, et al. Multisection 1H magnetic resonance spectroscopic imaging assessment of glioma response to chemotherapy. J Neurooncol 2006; 76: 185-191. (Pubitemid 43125747)
4. Leimgruber A, Ostermann S, Yeon EJ, et al. Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial. Int J Radiat Oncol Biol Phys 2006; 64: 869-875. (Pubitemid 43183587)
5. Akella NS, Twieg DB, Mikkelsen T, et al. Assessment of brain tumor angiogenesis inhibitors using perfusion magnetic resonance imaging: quality and analysis results of a phase I trial. J Magn Reson Imaging 2004; 20: 913-922. (Pubitemid 39577891)
6. Tomura N, Narita K, Izumi J, et al. Diffusion changes in a tumor and peritumoral tissue after stereotactic irradiation for brain tumors: possible prediction of treatment response. J Comput Assist Tomogr 2006; 30: 496-500. (Pubitemid 43922271)
7. Hamstra DA, Rehemtulla A, Ross BD,. Diffusion magnetic resonance imaging: a biomarker for treatment response in oncology. J Clin Oncol 2007; 25: 4104-4109. (Pubitemid 47495868)
8. Gambhir SS,. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer 2002; 2: 683-693. (Pubitemid 37328919)
9. Wong TZ, van der Westhuizen GJ, Coleman RE,. Positron emission tomography imaging of brain tumors. Neuroimaging Clin N Am 2002; 12: 615-626. (Pubitemid 36015495)
10. Ardenkjaer-Larsen JH, Fridlund B, Gram A, et al. Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR. Proc Natl Acad Sci U S A 2003; 100: 10158-10163. (Pubitemid 37071849)
11. Day SE, Kettunen MI, Gallagher FA, et al. Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med 2007; 13: 1382-1387. (Pubitemid 350073590)
12. Chen AP, Albers MJ, Cunningham CH, et al. Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-initial experience. Magn Reson Med 2007; 58: 1099-1106. (Pubitemid 350234196)
13. Albers MJ, Bok R, Chen AP, et al. Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. Cancer Res 2008; 68: 8607-8615.
14. Golman K, Petersson JS, Magnusson P, et al. Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI. Magn Reson Med 2008; 59: 1005-1013. (Pubitemid 351590513)
15. Hu S, Lustig M, Balakrishnan A, et al. 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer. Magn Reson Med 2010; 63: 312-321.
16. Park I, Larson PE, Zierhut ML, et al. Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors. Neuro Oncol 2010; 12: 133-144.
17. Ardenkjaer-Larsen JH, Macholl S, Johannesson H,. Dynamic nuclear polarization with trityls at 1.2 K. Appl Magn Reson 2008; 34: 509-522.
18. Derby K, Tropp J, Hawryszko C,. Design and evaluation of a novel dual-tuned resonator for spectroscopic imaging. J Magn Reson 1990; 86: 645-651.
19. Cunningham CH, Chen AP, Albers MJ, et al. Double spin-echo sequence for rapid spectroscopic imaging of hyperpolarized 13C. J Magn Reson 2007; 187: 357-362. (Pubitemid 47069025)
20. Zhao L, Mulkern R, Tseng CH, et al. Gradient-echo imaging considerations for hyperpolarized 129Xe MR. J Magn Reson B 1996; 113: 179-183. (Pubitemid 126758765)
21. Nelson SJ,. Analysis of volume MRI and MR spectroscopic imaging data for the evaluation of patients with brain tumors. Magn Reson Med 2001; 46: 228-239. (Pubitemid 32703267)
22. Cunningham CH, Vigneron DB, Chen AP, et al. Design of flyback echo-planar readout gradients for magnetic resonance spectroscopic imaging. Magn Reson Med 2005; 54: 1286-1289. (Pubitemid 41567210)
23. Haacke EM, Brown RW, Thompson MR, Venkatesan R,. Magnetic Resonance Imaging: physical principles and sequence design 1st ed. New York: Wiley-Liss; 1999.
24. Huang F, Kavan P, Guiot MC, Markovic Y, Roberge D,. When temozolomide alone fails: adding procarbazine in salvage therapy of glioma. Can J Neurol Sci 2008; 35: 192-197. (Pubitemid 351831056)
25. Brandes AA, Tosoni A, Basso U, et al. Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). J Clin Oncol 2004; 22: 4779-4786.
26. Walker P, Tizon X, Parfait S, et al. Evaluation of early response to temozolomide and radiotherapy with magnetic resonance imaging and proton magnetic resonance spectroscopy in human glioma models in nude rats. In: Proceedings of the 99th Annual Meeting of AACR, San Diego, 2008 (abstract 3733).