Magnetic resonance imaging with hyperpolarized [1,4- 13C 2]fumarate allows detection of early renal acute tubular necrosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 33, 2012, Pages 13374-13379

  Clatworthy, Menna R ^a,b   Kettunen, Mikko I ^c,d   Hu, De En ^c,d   Mathews, Rebeccah J ^a   Witney, Timothy H ^c,d   Kennedy, Brett W C ^c,d   Bohndiek, Sarah E ^c,d   Gallagher, Ferdia A ^c,d   Jarvis, Lorna B ^a   Smith, Kenneth G C ^a,b   Brindle, Kevin M ^c,d  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Hyperpolarization; MRI

Indexed keywords

CARBON 13; FUMARIC ACID; LACTATE[1 13 CARBON]; MALIC ACID; PYRUVATE [1 13 CARBON]; UNCLASSIFIED DRUG;

ACUTE GLOMERULONEPHRITIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; INFLAMMATION; KIDNEY DYSFUNCTION; KIDNEY TUBULE NECROSIS; LUPUS ERYTHEMATOSUS NEPHRITIS; MAGNETIC RESONANCE SPECTROSCOPIC IMAGING CARBON 13; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ANIMALS; CARBON ISOTOPES; EARLY DIAGNOSIS; FOLIC ACID; FUMARATES; HUMANS; KIDNEY; KIDNEY TUBULAR NECROSIS, ACUTE; KINETICS; LUPUS NEPHRITIS; MAGNETIC RESONANCE IMAGING; MALATES; MICE; MICE, INBRED C57BL; PYRUVIC ACID;

EID: 84865191464     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1205539109     Document Type: Article

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