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Volumn 8, Issue 8, 2013, Pages

Implication of IRF4 Aberrant Gene Expression in the Acute Leukemias of Childhood

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LEUKEMIA; ARTICLE; B LYMPHOCYTE; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CELL MATURATION; CELL POPULATION; CHILD; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; CYTOGENETICS; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IRF4 GENE; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRE B LYMPHOCYTE; PRESCHOOL CHILD; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; UPREGULATION; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; B CELL LEUKEMIA; CASE CONTROL STUDY; GENE EXPRESSION REGULATION; GENETICS; INFANT; MORTALITY; NEWBORN; PATHOLOGY; RECURRENT DISEASE; SURVIVAL; T CELL LEUKEMIA; TUMOR CELL LINE;

EID: 84881568102     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072326     Document Type: Article
Times cited : (18)

References (51)
  • 2
    • 84892790243 scopus 로고    scopus 로고
    • Childhood leukemia and lymphoma: time trends and factors affecting survival in five Southern and Eastern European Cancer Registries
    • Petridou ET, Dimitrova N, Eser S, Kachanov D, Karakilinc H, et al. (2013) Childhood leukemia and lymphoma: time trends and factors affecting survival in five Southern and Eastern European Cancer Registries. Cancer Causes Control 24: 1111-1118.
    • (2013) Cancer Causes Control , vol.24 , pp. 1111-1118
    • Petridou, E.T.1    Dimitrova, N.2    Eser, S.3    Kachanov, D.4    Karakilinc, H.5
  • 3
    • 33746498580 scopus 로고    scopus 로고
    • Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
    • Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, et al. (2006) Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 442: 818-822.
    • (2006) Nature , vol.442 , pp. 818-822
    • Krivtsov, A.V.1    Twomey, D.2    Feng, Z.3    Stubbs, M.C.4    Wang, Y.5
  • 4
    • 0142062911 scopus 로고    scopus 로고
    • MLL-rearranged leukemias: insights from gene expression profiling
    • Armstrong SA, Golub TR, Korsmeyer SJ, (2003) MLL-rearranged leukemias: insights from gene expression profiling. Semin Hematol 40: 268-273.
    • (2003) Semin Hematol , vol.40 , pp. 268-273
    • Armstrong, S.A.1    Golub, T.R.2    Korsmeyer, S.J.3
  • 5
    • 77954671464 scopus 로고    scopus 로고
    • Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development
    • Boiers C, Buza-Vidas N, Jensen CT, Pronk CJ, Kharazi S, et al. (2010) Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development. Blood 115: 5061-5068.
    • (2010) Blood , vol.115 , pp. 5061-5068
    • Boiers, C.1    Buza-Vidas, N.2    Jensen, C.T.3    Pronk, C.J.4    Kharazi, S.5
  • 6
    • 0042440852 scopus 로고    scopus 로고
    • Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements
    • Tsutsumi S, Taketani T, Nishimura K, Ge X, Taki T, et al. (2003) Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements. Cancer Res 63: 4882-4887.
    • (2003) Cancer Res , vol.63 , pp. 4882-4887
    • Tsutsumi, S.1    Taketani, T.2    Nishimura, K.3    Ge, X.4    Taki, T.5
  • 7
    • 19044399684 scopus 로고    scopus 로고
    • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
    • Yeoh EJ, Ross ME, Shurtleff SA, Williams WK, Patel D, et al. (2002) Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 1: 133-143.
    • (2002) Cancer Cell , vol.1 , pp. 133-143
    • Yeoh, E.J.1    Ross, M.E.2    Shurtleff, S.A.3    Williams, W.K.4    Patel, D.5
  • 8
    • 0041370095 scopus 로고    scopus 로고
    • Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
    • Ayton PM, Cleary ML, (2003) Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev 17: 2298-2307.
    • (2003) Genes Dev , vol.17 , pp. 2298-2307
    • Ayton, P.M.1    Cleary, M.L.2
  • 10
    • 38349177497 scopus 로고    scopus 로고
    • MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment
    • Stubbs MC, Kim YM, Krivtsov AV, Wright RD, Feng Z, et al. (2008) MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment. Leukemia 22: 66-77.
    • (2008) Leukemia , vol.22 , pp. 66-77
    • Stubbs, M.C.1    Kim, Y.M.2    Krivtsov, A.V.3    Wright, R.D.4    Feng, Z.5
  • 11
    • 2542442633 scopus 로고    scopus 로고
    • Transcriptional control of early B cell development
    • Busslinger M, (2004) Transcriptional control of early B cell development. Annu Rev Immunol 22: 55-79.
    • (2004) Annu Rev Immunol , vol.22 , pp. 55-79
    • Busslinger, M.1
  • 12
    • 52049093870 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 and 8 in B-cell development
    • Lu R, (2008) Interferon regulatory factor 4 and 8 in B-cell development. Trends Immunol 29: 487-492.
    • (2008) Trends Immunol , vol.29 , pp. 487-492
    • Lu, R.1
  • 13
    • 84859713325 scopus 로고    scopus 로고
    • The diverse roles of IRF4 in late germinal center B-cell differentiation
    • De Silva NS, Simonetti G, Heise N, Klein U, (2012) The diverse roles of IRF4 in late germinal center B-cell differentiation. Immunol Rev 247: 73-92.
    • (2012) Immunol Rev , vol.247 , pp. 73-92
    • De Silva, N.S.1    Simonetti, G.2    Heise, N.3    Klein, U.4
  • 14
    • 15444346834 scopus 로고    scopus 로고
    • Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
    • Mittrucker HW, Matsuyama T, Grossman A, Kundig TM, Potter J, et al. (1997) Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275: 540-543.
    • (1997) Science , vol.275 , pp. 540-543
    • Mittrucker, H.W.1    Matsuyama, T.2    Grossman, A.3    Kundig, T.M.4    Potter, J.5
  • 15
    • 0033400453 scopus 로고    scopus 로고
    • Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4
    • Gupta S, Jiang M, Anthony A, Pernis AB, (1999) Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4. J Exp Med 190: 1837-1848.
    • (1999) J Exp Med , vol.190 , pp. 1837-1848
    • Gupta, S.1    Jiang, M.2    Anthony, A.3    Pernis, A.B.4
  • 16
    • 33745182931 scopus 로고    scopus 로고
    • Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
    • Klein U, Casola S, Cattoretti G, Shen Q, Lia M, et al. (2006) Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol 7: 773-782.
    • (2006) Nat Immunol , vol.7 , pp. 773-782
    • Klein, U.1    Casola, S.2    Cattoretti, G.3    Shen, Q.4    Lia, M.5
  • 18
    • 0034678445 scopus 로고    scopus 로고
    • Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB
    • Grumont RJ, Gerondakis S, (2000) Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB. J Exp Med 191: 1281-1292.
    • (2000) J Exp Med , vol.191 , pp. 1281-1292
    • Grumont, R.J.1    Gerondakis, S.2
  • 19
    • 55749111381 scopus 로고    scopus 로고
    • IRF-4 functions as a tumor suppressor in early B-cell development
    • Acquaviva J, Chen X, Ren R, (2008) IRF-4 functions as a tumor suppressor in early B-cell development. Blood 112: 3798-3806.
    • (2008) Blood , vol.112 , pp. 3798-3806
    • Acquaviva, J.1    Chen, X.2    Ren, R.3
  • 20
    • 0032697261 scopus 로고    scopus 로고
    • Detection of MUM1/IRF4-IgH fusion in multiple myeloma
    • Yoshida S, Nakazawa N, Iida S, Hayami Y, Sato S, et al. (1999) Detection of MUM1/IRF4-IgH fusion in multiple myeloma. Leukemia 13: 1812-1816.
    • (1999) Leukemia , vol.13 , pp. 1812-1816
    • Yoshida, S.1    Nakazawa, N.2    Iida, S.3    Hayami, Y.4    Sato, S.5
  • 21
    • 0029928685 scopus 로고    scopus 로고
    • A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes
    • Yamagata T, Nishida J, Tanaka S, Sakai R, Mitani K, et al. (1996) A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes. Mol Cell Biol 16: 1283-1294.
    • (1996) Mol Cell Biol , vol.16 , pp. 1283-1294
    • Yamagata, T.1    Nishida, J.2    Tanaka, S.3    Sakai, R.4    Mitani, K.5
  • 22
    • 76649135152 scopus 로고    scopus 로고
    • IRF4 gene rearrangements define a subgroup of CD30-positive cutaneous T-cell lymphoma: a study of 54 cases
    • Pham-Ledard A, Prochazkova-Carlotti M, Laharanne E, Vergier B, Jouary T, et al. (2009) IRF4 gene rearrangements define a subgroup of CD30-positive cutaneous T-cell lymphoma: a study of 54 cases. J Invest Dermatol 130: 816-825.
    • (2009) J Invest Dermatol , vol.130 , pp. 816-825
    • Pham-Ledard, A.1    Prochazkova-Carlotti, M.2    Laharanne, E.3    Vergier, B.4    Jouary, T.5
  • 24
    • 0037114759 scopus 로고    scopus 로고
    • Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia
    • Chang CC, Lorek J, Sabath DE, Li Y, Chitambar CR, et al. (2002) Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia. Blood 100: 4671-4675.
    • (2002) Blood , vol.100 , pp. 4671-4675
    • Chang, C.C.1    Lorek, J.2    Sabath, D.E.3    Li, Y.4    Chitambar, C.R.5
  • 25
    • 0036322325 scopus 로고    scopus 로고
    • MUM1/IRF4 expression is an unfavorable prognostic factor in B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)
    • Ito M, Iida S, Inagaki H, Tsuboi K, Komatsu H, et al. (2002) MUM1/IRF4 expression is an unfavorable prognostic factor in B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Jpn J Cancer Res 93: 685-694.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 685-694
    • Ito, M.1    Iida, S.2    Inagaki, H.3    Tsuboi, K.4    Komatsu, H.5
  • 26
    • 38849188479 scopus 로고    scopus 로고
    • MUM1/IRF4 expression in the circulating compartment of chronic lymphocytic leukemia
    • Craig F, Soma L, Melan M, Kant J, Swerdlow S, (2008) MUM1/IRF4 expression in the circulating compartment of chronic lymphocytic leukemia. Leuk Lymphoma 49: 273-280.
    • (2008) Leuk Lymphoma , vol.49 , pp. 273-280
    • Craig, F.1    Soma, L.2    Melan, M.3    Kant, J.4    Swerdlow, S.5
  • 27
    • 77950961443 scopus 로고    scopus 로고
    • Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia
    • Allan JM, Sunter NJ, Bailey JR, Pettitt AR, Harris RJ, et al. (2010) Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia. Leukemia 24: 877-881.
    • (2010) Leukemia , vol.24 , pp. 877-881
    • Allan, J.M.1    Sunter, N.J.2    Bailey, J.R.3    Pettitt, A.R.4    Harris, R.J.5
  • 28
    • 45849102392 scopus 로고    scopus 로고
    • In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties
    • le Viseur C, Hotfilder M, Bomken S, Wilson K, Rottgers S, et al. (2008) In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties. Cancer Cell 14: 47-58.
    • (2008) Cancer Cell , vol.14 , pp. 47-58
    • le Viseur, C.1    Hotfilder, M.2    Bomken, S.3    Wilson, K.4    Rottgers, S.5
  • 29
    • 74149093117 scopus 로고    scopus 로고
    • An intronic polymorphism of IRF4 gene influences gene transcription in vitro and shows a risk association with childhood acute lymphoblastic leukemia in males
    • Do TN, Ucisik-Akkaya E, Davis CF, Morrison BA, Dorak MT, (2010) An intronic polymorphism of IRF4 gene influences gene transcription in vitro and shows a risk association with childhood acute lymphoblastic leukemia in males. Biochim Biophys Acta 1802: 292-300.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 292-300
    • Do, T.N.1    Ucisik-Akkaya, E.2    Davis, C.F.3    Morrison, B.A.4    Dorak, M.T.5
  • 30
    • 70249146146 scopus 로고    scopus 로고
    • Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression
    • Lambrou GI, Vlahopoulos S, Papathanasiou C, Papanikolaou M, Karpusas M, et al. (2009) Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression. Leuk Res.
    • (2009) Leuk Res
    • Lambrou, G.I.1    Vlahopoulos, S.2    Papathanasiou, C.3    Papanikolaou, M.4    Karpusas, M.5
  • 31
    • 0030970798 scopus 로고    scopus 로고
    • Clinical features and treatment outcome of children with biphenotypic CD2+ CD19+ acute lymphoblastic leukemia: a Children's Cancer Group study
    • Uckun FM, Gaynon P, Sather H, Arthur D, Trigg M, et al. (1997) Clinical features and treatment outcome of children with biphenotypic CD2+ CD19+ acute lymphoblastic leukemia: a Children's Cancer Group study. Blood 89: 2488-2493.
    • (1997) Blood , vol.89 , pp. 2488-2493
    • Uckun, F.M.1    Gaynon, P.2    Sather, H.3    Arthur, D.4    Trigg, M.5
  • 32
    • 0027303092 scopus 로고
    • Clinical and biologic relevance of immunologic marker studies in childhood acute lymphoblastic leukemia
    • Pui CH, Behm FG, Crist WM, (1993) Clinical and biologic relevance of immunologic marker studies in childhood acute lymphoblastic leukemia. Blood 82: 343-362.
    • (1993) Blood , vol.82 , pp. 343-362
    • Pui, C.H.1    Behm, F.G.2    Crist, W.M.3
  • 33
    • 77952305440 scopus 로고    scopus 로고
    • Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial
    • Moorman AV, Ensor HM, Richards SM, Chilton L, Schwab C, et al. (2010) Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. Lancet Oncol 11: 429-438.
    • (2010) Lancet Oncol , vol.11 , pp. 429-438
    • Moorman, A.V.1    Ensor, H.M.2    Richards, S.M.3    Chilton, L.4    Schwab, C.5
  • 34
    • 0034306317 scopus 로고    scopus 로고
    • Expression of interferon regulatory factor 4 in chronic myeloid leukemia: correlation with response to interferon alfa therapy
    • Schmidt M, Hochhaus A, Konig-Merediz SA, Brendel C, Proba J, et al. (2000) Expression of interferon regulatory factor 4 in chronic myeloid leukemia: correlation with response to interferon alfa therapy. J Clin Oncol 18: 3331-3338.
    • (2000) J Clin Oncol , vol.18 , pp. 3331-3338
    • Schmidt, M.1    Hochhaus, A.2    Konig-Merediz, S.A.3    Brendel, C.4    Proba, J.5
  • 35
    • 0029763203 scopus 로고    scopus 로고
    • Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1
    • Brass AL, Kehrli E, Eisenbeis CF, Storb U, Singh H, (1996) Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. Genes Dev 10: 2335-2347.
    • (1996) Genes Dev , vol.10 , pp. 2335-2347
    • Brass, A.L.1    Kehrli, E.2    Eisenbeis, C.F.3    Storb, U.4    Singh, H.5
  • 36
    • 33747133955 scopus 로고    scopus 로고
    • Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation
    • Sciammas R, Shaffer AL, Schatz JH, Zhao H, Staudt LM, et al. (2006) Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 25: 225-236.
    • (2006) Immunity , vol.25 , pp. 225-236
    • Sciammas, R.1    Shaffer, A.L.2    Schatz, J.H.3    Zhao, H.4    Staudt, L.M.5
  • 37
    • 84881587456 scopus 로고    scopus 로고
    • PubMed website. Available: ID = GDS1095:37625/Accessed 2013 May 5
    • PubMed website. Available: http://www.ncbi.nlm.nih.gov/geo/tools/profileGraph.cgi? ID = GDS1095:37625/Accessed 2013 May 5.
  • 38
    • 30344462965 scopus 로고    scopus 로고
    • Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex
    • Kanno Y, Levi BZ, Tamura T, Ozato K, (2005) Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex. J Interferon Cytokine Res 25: 770-779.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 770-779
    • Kanno, Y.1    Levi, B.Z.2    Tamura, T.3    Ozato, K.4
  • 39
    • 34548140141 scopus 로고    scopus 로고
    • The role of the interferon regulatory factor (IRF) family in dendritic cell development and function
    • Gabriele L, Ozato K, (2007) The role of the interferon regulatory factor (IRF) family in dendritic cell development and function. Cytokine Growth Factor Rev 18: 503-510.
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 503-510
    • Gabriele, L.1    Ozato, K.2
  • 40
    • 27744509044 scopus 로고    scopus 로고
    • Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages
    • Lehtonen A, Veckman V, Nikula T, Lahesmaa R, Kinnunen L, et al. (2005) Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. J Immunol 175: 6570-6579.
    • (2005) J Immunol , vol.175 , pp. 6570-6579
    • Lehtonen, A.1    Veckman, V.2    Nikula, T.3    Lahesmaa, R.4    Kinnunen, L.5
  • 41
    • 80053926066 scopus 로고    scopus 로고
    • Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development
    • Yamamoto M, Kato T, Hotta C, Nishiyama A, Kurotaki D, et al. (2011) Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development. PLoS One 6: e25812.
    • (2011) PLoS One , vol.6
    • Yamamoto, M.1    Kato, T.2    Hotta, C.3    Nishiyama, A.4    Kurotaki, D.5
  • 42
    • 0031964844 scopus 로고    scopus 로고
    • Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias
    • Schmidt M, Nagel S, Proba J, Thiede C, Ritter M, et al. (1998) Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias. Blood 91: 22-29.
    • (1998) Blood , vol.91 , pp. 22-29
    • Schmidt, M.1    Nagel, S.2    Proba, J.3    Thiede, C.4    Ritter, M.5
  • 43
    • 0035383797 scopus 로고    scopus 로고
    • Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-alpha
    • Schmidt M, Hochhaus A, Nitsche A, Hehlmann R, Neubauer A, (2001) Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-alpha. Blood 97: 3648-3650.
    • (2001) Blood , vol.97 , pp. 3648-3650
    • Schmidt, M.1    Hochhaus, A.2    Nitsche, A.3    Hehlmann, R.4    Neubauer, A.5
  • 44
    • 0036179847 scopus 로고    scopus 로고
    • The role of IRF-4 in B and T cell activation and differentiation
    • Pernis AB, (2002) The role of IRF-4 in B and T cell activation and differentiation. J Interferon Cytokine Res 22: 111-120.
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 111-120
    • Pernis, A.B.1
  • 46
    • 65549112644 scopus 로고    scopus 로고
    • Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas
    • Malumbres R, Sarosiek KA, Cubedo E, Ruiz JW, Jiang X, et al. (2009) Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas. Blood 113: 3754-3764.
    • (2009) Blood , vol.113 , pp. 3754-3764
    • Malumbres, R.1    Sarosiek, K.A.2    Cubedo, E.3    Ruiz, J.W.4    Jiang, X.5
  • 48
    • 0034654411 scopus 로고    scopus 로고
    • A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells
    • Falini B, Fizzotti M, Pucciarini A, Bigerna B, Marafioti T, et al. (2000) A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood 95: 2084-2092.
    • (2000) Blood , vol.95 , pp. 2084-2092
    • Falini, B.1    Fizzotti, M.2    Pucciarini, A.3    Bigerna, B.4    Marafioti, T.5
  • 49
    • 3242759829 scopus 로고    scopus 로고
    • Enhanced TCR-induced apoptosis in interferon regulatory factor 4-deficient CD4(+) Th cells
    • Lohoff M, Mittrucker HW, Brustle A, Sommer F, Casper B, et al. (2004) Enhanced TCR-induced apoptosis in interferon regulatory factor 4-deficient CD4(+) Th cells. J Exp Med 200: 247-253.
    • (2004) J Exp Med , vol.200 , pp. 247-253
    • Lohoff, M.1    Mittrucker, H.W.2    Brustle, A.3    Sommer, F.4    Casper, B.5
  • 50
    • 31344450346 scopus 로고    scopus 로고
    • Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein
    • Lee CH, Melchers M, Wang H, Torrey TA, Slota R, et al. (2006) Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein. J Exp Med 203: 63-72.
    • (2006) J Exp Med , vol.203 , pp. 63-72
    • Lee, C.H.1    Melchers, M.2    Wang, H.3    Torrey, T.A.4    Slota, R.5
  • 51
    • 34548237299 scopus 로고    scopus 로고
    • A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
    • Saito M, Gao J, Basso K, Kitagawa Y, Smith PM, et al. (2007) A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 12: 280-292.
    • (2007) Cancer Cell , vol.12 , pp. 280-292
    • Saito, M.1    Gao, J.2    Basso, K.3    Kitagawa, Y.4    Smith, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.