Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

Veterinary Parasitology

Volumn 196, Issue 3-4, 2013, Pages 373-381

  Vokřál, Ivan ^a   Jirásko, Robert ^b   Stuchlíková, Lucie ^a   Bártíková, Hana ^a   Szotáková, Barbora ^a   Lamka, Jiří ^a   Várady, Marián ^c   Skálová, Lenka ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b UNIVERSITY OF PARDUBICE   (Czech Republic)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Drug resistance; Nematodes; Strain differences; UDP glucosyltransferase

Indexed keywords

ALBENDAZOLE; ALBENDAZOLE GLUCOSIDE; ALBENDAZOLE SULFONE; ALBENDAZOLE SULFOXIDE; BENZIMIDAZOLE DERIVATIVE; CATALASE; DRUG METABOLITE; GLUCOSYLTRANSFERASE; PEROXIDASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSYLTRANSFERASE;

ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DRUG OXIDATION; DRUG RESISTANCE; DRUG SENSITIVITY; DRUG TRANSFORMATION; ENZYME ACTIVITY; EX VIVO STUDY; HAEMONCHUS CONTORTUS; IN VITRO STUDY; NONHUMAN; STRAIN DIFFERENCE;

HAEMONCHUS CONTORTUS; NEMATODA; OVIS ARIES; VERMES;

ABZ; ABZ-SO; ABZ-SO(2); ALBENDAZOLE; ALBENDAZOLE SULFONE; ALBENDAZOLE SULFOXIDE; DRUG RESISTANCE; NEMATODES; STRAIN-DIFFERENCES; UDP-GLUCOSYLTRANSFERASE;

ALBENDAZOLE; ANIMALS; ANTHELMINTICS; CATALASE; DRUG RESISTANCE; ENZYME ACTIVATION; HAEMONCHUS; MOLECULAR STRUCTURE; PEROXIDASE; SHEEP; SHEEP DISEASES; SUPEROXIDE DISMUTASE;

EID: 84881556939     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2013.03.018     Document Type: Article

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