Altered drug influx/efflux and enhanced metabolic activity in triclabendazole-resistant liver flukes

Parasitology

Volumn 131, Issue 4, 2005, Pages 501-510

  Alvarez, L I ^a,b   Solana, H D ^a,c   Mottier, M L ^a,b   Virkel, G L ^a,b   Fairweather, I ^d   Lanusse, C E ^a,b  

^a UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c Universidad Provincial del Sudoeste   (Argentina)

^d QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Drug diffusion and metabolism; Fasciola hepatica; Resistance mechanisms; Triclabendazole

Indexed keywords

TRICLABENDAZOLE;

ARTICLE; BIOTRANSFORMATION; BLOOD FLOW; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG DIFFUSION; DRUG METABOLISM; FASCIOLA HEPATICA; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SHEEP;

ANIMALS; ANTHELMINTICS; BENZIMIDAZOLES; BIOTRANSFORMATION; CELLS, CULTURED; DIFFUSION; DRUG RESISTANCE; FASCIOLA HEPATICA; FASCIOLIASIS; METABOLIC CLEARANCE RATE; PARASITIC SENSITIVITY TESTS; SHEEP;

ANIMALIA; DIGENEA (FLUKES); FASCIOLA HEPATICA; OVIS ARIES;

EID: 23944452203     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182005007997     Document Type: Article

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