The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

Parasitology

Volumn 139, Issue 10, 2012, Pages 1309-1316

  Vokřál, Ivan ^a   Bártíková, Hana ^a   Prchal, LUKáš ^a   Stuchlíková, Lucie ^a   Skálová, Lenka ^a   Szotáková, Barbora ^a   Lamka, JIří ^a   Várady, MARIáN ^b   Kubíček, Vladimír ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

carbonyl reductases; drug metabolism; helminths; strain differences; UDP glucosyltransferase

Indexed keywords

CARBONYL DERIVATIVE; DRUG METABOLITE; FLUBENDAZOLE; GLUCOSIDE; MENADIONE; METYRAPONE; NALOXONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ARTICLE; DRUG METABOLISM; DRUG SENSITIVITY; DRUG TRANSFORMATION; EX VIVO STUDY; HAEMONCHOSIS; HAEMONCHUS CONTORTUS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTHELMINTICS; DRUG RESISTANCE; HAEMONCHIASIS; HAEMONCHUS; MEBENDAZOLE; SHEEP; SHEEP DISEASES;

CAPRA HIRCUS; HAEMONCHUS CONTORTUS; OVIS ARIES; VERMES;

EID: 84866135502     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182012000595     Document Type: Article

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