Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages

Biochemical and Biophysical Research Communications

Volumn 438, Issue 1, 2013, Pages 122-128

  Sung, Nak Yun ^a   Yang, Mi So ^b   Song, Du Sub ^a,c   Kim, Jae Kyung ^a   Park, Jong Heum ^a   Song, Beom Seok ^a   Park, Sang Hyun ^a   Lee, Ju Woon ^a   Park, Hyun Jin ^c   Kim, Jae Hun ^a   Byun, Eui Baek ^a   Byun, Eui Hong ^d  

^a Korea Atomic Energy Research Institute   (South Korea)

^b Chungnam National University   (South Korea)

^c Korea University   (South Korea)

^d Kongju National University   (South Korea)

Author keywords

Cytokine; Mitogen activated protein kinases; Nuclear factor B; Procyanidin B2; Toll like receptor

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROCYANIDIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION;

CYTOKINE; DITHIOTHREITOL; DTT; FITC; FLUORESCEIN ISOTHIOCYANATE; IΚ-B; IFN; IL; IL-1 RECEPTOR-ASSOCIATED KINASE; INHIBITOR OF ΚB; INTERFERON; INTERLEUKIN; IRAK; LIPOPOLYSACCHARIDE; LPS; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; MITOGEN-ACTIVATED PROTEIN KINASES; MYD88; MYELOID DIFFERENTIATION FACTOR 88; NF-ΚB; NUCLEAR FACTOR ΚB; NUCLEAR FACTOR-ΚB; PBS; PE; PHENYLMETHANESULFONYL FLUORIDE; PHOSPHATE-BUFFERED SALINE; PHYCOERYTHRIN; PMSF; PROCYANIDIN B2; SDS; SOCS1; SODIUM DODECYL SULFATE; SUPPRESSOR OF CYTOKINE SIGNALING 1; TIR; TIR DOMAIN-CONTAINING ADAPTER-INDUCING INTERFERON-Β; TLR; TNF-Α; TOLL-INTERACTING PROTEIN; TOLL-LIKE RECEPTOR; TOLL/INTERLEUKIN-1 RECEPTOR HOMOLOGY; TOLLIP; TRIF; TUMOR NECROSIS FACTOR-Α;

ANIMALS; BIFLAVONOIDS; CATECHIN; CELL LINE; DOWN-REGULATION; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MACROPHAGES; MICE; PROANTHOCYANIDINS; TOLL-LIKE RECEPTOR 4;

EID: 84881551722     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.07.038     Document Type: Article

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