ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors

Biochemical Journal

Volumn 454, Issue 2, 2013, Pages 201-208

  Halasi, Marianna ^a   Wang, Ming ^a   Chavan, Tanmay S ^a   Gaponenko, Vadim ^a   Hay, Nissim ^a,b   Gartel, Andrei L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

Catalase; Forkhead box protein M1 (FOXM1); N acetyl L cysteine (NAC); Proteasome inhibitor; Reactive oxygen species (ROS)

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BORTEZOMIB; CATALASE; HYDROGEN PEROXIDE; LACTACYSTIN; PIPERLONGUMINE; PROTEASOME INHIBITOR; REACTIVE OXYGEN METABOLITE; THIOSTREPTON; TROLOX C; UBIQUITIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; DOWN REGULATION; DRUG ANTAGONISM; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; WESTERN BLOTTING;

ACETYLCYSTEINE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CATALASE; CELL LINE, TUMOR; CHROMANS; CYTOMEGALOVIRUS; DIOXOLANES; FORKHEAD TRANSCRIPTION FACTORS; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PROTEIN STABILITY; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; UBIQUITINATED PROTEINS; VIRAL PROTEINS;

EID: 84881522811     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130282     Document Type: Article

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