Drug-loaded sickle cells programmed ex vivo for delayed hemolysis target hypoxic tumor microvessels and augment tumor drug delivery

Journal of Controlled Release

Volumn 171, Issue 2, 2013, Pages 184-192

  Choe, Se Woon ^a   Terman, David S ^b   Rivers, Angela E ^c   Rivera, Jose ^d   Lottenberg, Richard ^e   Sorg, Brian S ^f  

^a Biomedical IT Convergence Center Gumi Electronics and Information Technology Research Institute   (South Korea)

^b Jenomic   (United States)

^c UNIVERSITY OF ILLINOIS   (United States)

^d United States of America   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Blood; Cancer; Carrier; Chemotherapy; Particle; Photosensitizer

Indexed keywords

BLOOD; BLOOD VESSELS; CHEMOTHERAPY; HYPERSPECTRAL IMAGING; OXIDATION; PARTICLES (PARTICULATE MATTER); PHOTOSENSITIZERS; SPECTROSCOPY;

CANCER; CARRIER; CONCEPTUAL APPROACHES; OXYGEN SATURATION LEVELS; SYSTEMIC ADMINISTRATION; TUMOR DRUG DELIVERIES; VIDEO MICROSCOPY; WINDOW CHAMBERS;

TUMORS;

CALCEIN; CISPLATIN; HEMOGLOBIN; PHOTOSENSITIZING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ERYTHROCYTE; EX VIVO STUDY; FEMALE; HEMOLYSIS; HYPOXIC CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PHOTOLYSIS; PHOTOOXIDATION; PHOTOSENSITIZATION; PRIORITY JOURNAL; SICKLE CELL; VASCULAR TUMOR;

BLOOD; CANCER; CARRIER; CHEMOTHERAPY; PARTICLE; PHOTOSENSITIZER;

ANEMIA, SICKLE CELL; ANIMALS; ANOXIA; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; ERYTHROCYTES; FEMALE; FLUORESCENT DYES; HEMOLYSIS; HUMANS; LIGHT; LIVER; MICE; MICE, INBRED C57BL; MICE, NUDE; MICE, TRANSGENIC; MICROVESSELS; NEOPLASMS; OXIDATION-REDUCTION; PHOTOLYSIS; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS; SPLEEN;

EID: 84881520353     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.07.008     Document Type: Article

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