Survival of Primary Human Hepatocytes and Death of Induced Pluripotent Stem Cells in Media Lacking Glucose and Arginine

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Tomizawa, Minoru ^a   Shinozaki, Fuminobu ^a   Sugiyama, Takao ^a   Yamamoto, Shigenori ^a   Sueishi, Makoto ^a   Yoshida, Takanobu ^a  

^a SHIMOSHIZU HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GALACTOKINASE; GALACTOKINASE 1; GALACTOKINASE 2; GALACTOSE; GLUCOSE; ORNITHINE; ORNITHINE CARBAMOYLTRANSFERASE; PHENYLALANINE 4 MONOOXYGENASE; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; FETUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER CELL; NICK END LABELING; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; ARGININE; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CULTURE MEDIA; GLUCOSE; HEPATOCYTES; HUMANS; PLURIPOTENT STEM CELLS; STAINING AND LABELING;

EID: 84881515973     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071897     Document Type: Article

References (33)

1. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
2. Strom SC, Chowdhury JR, Fox IJ, (1999) Hepatocyte transplantation for the treatment of human disease. Semin Liver Dis 19: 39-48.
3. Si-Tayeb K, Noto FK, Nagaoka M, Li J, Battle MA, et al. (2010) Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology 51: 297-305.
4. Takayama K, Inamura M, Kawabata K, Sugawara M, Kikuchi K, et al. (2012) Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1alpha transduction. J Hepatol.
5. Okita K, Ichisaka T, Yamanaka S, (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
6. Miura K, Okada Y, Aoi T, Okada A, Takahashi K, et al. (2009) Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol 27: 743-745.
7. Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S, (2008) Generation of mouse induced pluripotent stem cells without viral vectors. Science 322: 949-953.
8. Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M, (2009) Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 85: 348-362.
9. Lin SL, Ying SY, (2013) Mechanism and method for generating tumor-free iPS cells using intronic microRNA miR-302 induction. Methods Mol Biol 936: 295-312.
10. Yakubov E, Rechavi G, Rozenblatt S, Givol D, (2010) Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Biochem Biophys Res Commun 394: 189-193.
11. Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, et al. (2008) Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26: 101-106.
12. Pierce GB Jr, Dixon FJ Jr, Verney EL, (1960) Teratocarcinogenic and tissue-forming potentials of the cell types comprising neoplastic embryoid bodies. Lab Invest 9: 583-602.
13. Kooreman NG, Wu JC, (2010) Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging. J R Soc Interface 7Suppl 6: S753-763.
14. Leffert HL, Paul D, (1972) Studies on primary cultures of differentiated fetal liver cells. J Cell Biol 52: 559-568.
15. Matsumoto K, Yamada K, Kohmura E, Kinoshita A, Hayakawa T, (1994) Role of pyruvate in ischaemia-like conditions on cultured neurons. Neurol Res 16: 460-464.
16. Ohira RH, Dipple KM, Zhang YH, McCabe ER, (2005) Human and murine glycerol kinase: influence of exon 18 alternative splicing on function. Biochem Biophys Res Commun 331: 239-246.
17. Ai Y, Jenkins NA, Copeland NG, Gilbert DH, Bergsma DJ, et al. (1995) Mouse galactokinase: isolation, characterization, and location on chromosome 11. Genome Res 5: 53-59.
18. Phillips JW, Jones ME, Berry MN, (2002) Implications of the simultaneous occurrence of hepatic glycolysis from glucose and gluconeogenesis from glycerol. Eur J Biochem 269: 792-797.
19. Sumida KD, Crandall SC, Chadha PL, Qureshi T, (2002) Hepatic gluconeogenic capacity from various precursors in young versus old rats. Metabolism 51: 876-880.
20. Wheatley DN, Scott L, Lamb J, Smith S, (2000) Single amino acid (arginine) restriction: growth and death of cultured HeLa and human diploid fibroblasts. Cell Physiol Biochem 10: 37-55.
21. Niwa A, Yamamoto K, Sorimachi K, Yasumura Y, (1980) Continuous culture of Reuber hepatoma cells in serum-free arginine-, glutamine- and tyrosine-deprived chemically defined medium. In Vitro 16: 987-993.
22. McGee MM, Greengard O, Knox WE, (1972) The quantitative determination of phenylalanine hydroxylase in rat tissues. Its developmental formation in liver. Biochem J 127: 669-674.
23. Tomizawa M, Toyama Y, Ito C, Toshimori K, Iwase K, et al. (2008) Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine. Cell Tissue Res 333: 17-27.
24. Nakamura T, Teramoto H, Tomita Y, Ichihara A, (1984) L-proline is an essential amino acid for hepatocyte growth in culture. Biochem Biophys Res Commun 122: 884-891.
25. Yamamoto H, Quinn G, Asari A, Yamanokuchi H, Teratani T, et al. (2003) Differentiation of embryonic stem cells into hepatocytes: biological functions and therapeutic application. Hepatology 37: 983-993.
26. Abe K, Niwa H, Iwase K, Takiguchi M, Mori M, et al. (1996) Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies. Exp Cell Res 229: 27-34.
27. Tanaka M, Okabe M, Suzuki K, Kamiya Y, Tsukahara Y, et al. (2009) Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development. Mech Dev 126: 665-676.
28. Yanai H, Nakamura K, Hijioka S, Kamei A, Ikari T, et al. (2010) Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency. J Biochem 148: 85-92.
29. Alekseenko LL, Zemelko VI, Zenin VV, Pugovkina NA, Kozhukharova IV, et al. (2012) Heat shock induces apoptosis in human embryonic stem cells but a premature senescence phenotype in their differentiated progeny. Cell Cycle 11: 3260-3269.
30. Cheng F, Ke Q, Chen F, Cai B, Gao Y, et al. (2012) Protecting against wayward human induced pluripotent stem cells with a suicide gene. Biomaterials 33: 3195-3204.
31. Conesa C, Doss MX, Antzelevitch C, Sachinidis A, Sancho J, et al. (2012) Identification of specific pluripotent stem cell death-inducing small molecules by chemical screening. Stem Cell Rev 8: 116-127.
32. Bieberich E, Silva J, Wang G, Krishnamurthy K, Condie BG, (2004) Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants. J Cell Biol 167: 723-734.
33. Folmes CD, Nelson TJ, Martinez-Fernandez A, Arrell DK, Lindor JZ, et al. (2011) Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. Cell Metab 14: 264-271.