메뉴 건너뛰기




Volumn 148, Issue 1, 2010, Pages 85-92

Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency

Author keywords

cell surface protein; colon adenocarcinoma; hDlk 1; hepatocellular carcinoma (HCC); small cell lung carcinoma

Indexed keywords

ALPHA FETOPROTEIN; DELTA LIKE 1 PROTEIN; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; DLK1 PROTEIN, HUMAN; MEMBRANE PROTEIN; SIGNAL PEPTIDE; TUMOR ANTIGEN;

EID: 77954419078     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq034     Document Type: Article
Times cited : (71)

References (51)
  • 1
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • Parkin, D.M., Bray, F., Ferlay, J., and Pisani, P. (2001) Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 94, 153-156
    • (2001) Int. J. Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El-Serag, H.B. and Mason, A.C. (1999) Rising incidence of hepatocellular carcinoma in the United States. New Engl. J. Med. 340, 745-750
    • (1999) New Engl. J. Med , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 3
    • 0034090264 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Okuda, K. (2000) Hepatocellular carcinoma. J. Hepatol 32, 225-237
    • (2000) J. Hepatol , vol.32 , pp. 225-237
    • Okuda, K.1
  • 4
    • 0031730288 scopus 로고    scopus 로고
    • Cloning of a membrane-spanning protein with epidermal growth factor-like repeat motifs from adrenal glomerulosa cells
    • Halder, S.K., Takemori, H, Hatano, O., Nonaka, Y., Wada, A., and Okamoto, M. (1998) Cloning of a membrane-spanning protein with epidermal growth factor-like repeat motifs from adrenal glomerulosa cells. Endocrinology 139, 3316-3328
    • (1998) Endocrinology , vol.139 , pp. 3316-3328
    • Halder, S.K.1    Takemori, H.2    Hatano, O.3    Nonaka, Y.4    Wada, A.5    Okamoto, M.6
  • 5
    • 0028017528 scopus 로고
    • Protein structure of fetal antigen 1 (FA1). A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2
    • Jensen, C.H., Krogh, T.N., Højrup, P., Clausen, P.P., Skjødt, K., Larsson, L.I., Enghild, J.J., and Teisner, B. (1994)Protein structure of fetal antigen 1 (FA1). A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2. Eur. J. Biochem. 225, 83-92
    • (1994) Eur. J. Biochem , vol.225 , pp. 83-92
    • Jensen, C.H.1    Krogh, T.N.2    Højrup, P.3    Clausen, P.P.4    Skjødt, K.5    Larsson, L.I.6    Enghild, J.J.7    Teisner, B.8
  • 6
    • 0027467416 scopus 로고
    • Dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line
    • Laborda, J., Sausville, E.A., Hoffman, T., and Notario, V. (1993) dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line. J. Biol. Chem. 268, 3817-3820
    • (1993) J. Biol. Chem , vol.268 , pp. 3817-3820
    • Laborda, J.1    Sausville, E.A.2    Hoffman, T.3    Notario, V.4
  • 7
    • 0028961044 scopus 로고
    • Dlk, pG2 and Pref-1 mRNAs encode similar proteins belonging to the EGF-like superfamily. Identification of polymorphic variants of this RNA
    • Lee, Y.L., Helman, L., Hoffman, T., and Laborda, J. (1995) dlk, pG2 and Pref-1 mRNAs encode similar proteins belonging to the EGF-like superfamily. Identification of polymorphic variants of this RNA. Biochim. Biophys. Acta 1261, 223-232
    • (1995) Biochim. Biophys. Acta , vol.1261 , pp. 223-232
    • Lee, Y.L.1    Helman, L.2    Hoffman, T.3    Laborda, J.4
  • 8
    • 0027245963 scopus 로고
    • Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
    • Smas, CM. and Sul, H.S. (1993) Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 73, 725-734
    • (1993) Cell , vol.73 , pp. 725-734
    • Smas, C.M.1    Sul, H.S.2
  • 9
    • 0033885174 scopus 로고    scopus 로고
    • Does fetal antigen 1 (FA1) identify cells with regenerative, endocrine and neuroendocrine potentials? A study of FA1 in embryonic, fetal, and placental tissue and in maternal circulation
    • Floridon, C, Jensen, C.H., Thorsen, P., Nielsen, O., Sunde, L., Westergaard, J.G., Thomsen, S.G., and Teisner, B. (2000) Does fetal antigen 1 (FA1) identify cells with regenerative, endocrine and neuroendocrine potentials? A study of FA1 in embryonic, fetal, and placental tissue and in maternal circulation. Differentiation 66, 49-59
    • (2000) Differentiation , vol.66 , pp. 49-59
    • Floridon, C.1    Jensen, C.H.2    Thorsen, P.3    Nielsen, O.4    Sunde, L.5    Westergaard, J.G.6    Thomsen, S.G.7    Teisner, B.8
  • 10
    • 0038325629 scopus 로고    scopus 로고
    • Isolation of hepatoblasts based on the expression of Dlk/Pref-1
    • Tanimizu, N., Nishikawa, M., Saito, H., Tsujimura, T., and Miyajima, A. (2003) Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J. Cell Sci. 116, 1775-1786
    • (2003) J. Cell Sci , vol.116 , pp. 1775-1786
    • Tanimizu, N.1    Nishikawa, M.2    Saito, H.3    Tsujimura, T.4    Miyajima, A.5
  • 12
    • 0033971947 scopus 로고    scopus 로고
    • The role of the epidermal growth factor-like protein dlk in cell differentiation
    • Laborda, J. (2000) The role of the epidermal growth factor-like protein dlk in cell differentiation. Histol. Histopathol. 15, 119-129
    • (2000) Histol. Histopathol , vol.15 , pp. 119-129
    • Laborda, J.1
  • 13
    • 0032532311 scopus 로고    scopus 로고
    • Notch and neurogenesis
    • Beatus, P. and Lendahl, U. (1999) Notch and neurogenesis. J. Neurosci. Res. 54, 125-136
    • (1999) J. Neurosci. Res , vol.54 , pp. 125-136
    • Beatus, P.1    Lendahl, U.2
  • 14
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., Rand, M.D., and Lake, R.J. (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 15
    • 0029923167 scopus 로고    scopus 로고
    • Characterization of Pref-1 and its inhibitory role in adipocyte differentiation
    • Smas, CM. and Sul, H.S. (1996) Characterization of Pref-1 and its inhibitory role in adipocyte differentiation. Int. J. Obes. Relat. Metab. Disord. 20 (Suppl. 3), S65-S72
    • (1996) Int. J. Obes. Relat. Metab. Disord , vol.20 , Issue.SUPPL. 3
    • Smas, C.M.1    Sul, H.S.2
  • 16
    • 0031774080 scopus 로고    scopus 로고
    • Recent progress in identifying genes regulating hematopoietic stem cell function and fate
    • Jordan, C.T. and Van Zant, G. (1998) Recent progress in identifying genes regulating hematopoietic stem cell function and fate. Curr. Opin. Cell Biol. 10, 716-720
    • (1998) Curr. Opin. Cell Biol , vol.10 , pp. 716-720
    • Jordan, C.T.1    Van Zant, G.2
  • 17
    • 0030936580 scopus 로고    scopus 로고
    • Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs
    • Moore, K.A., Pytowski, B., Witte, L., Hicklin, D., and Lemischka, I.R. (1997) Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs. Proc. Natl. Acad. Sci. USA 94, 4011-4016
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4011-4016
    • Moore, K.A.1    Pytowski, B.2    Witte, L.3    Hicklin, D.4    Lemischka, I.R.5
  • 18
    • 0027166743 scopus 로고
    • Fetal antigen 1 (FA1 in the human pancreas: Cell type expression, topological and quantitative variations during development
    • Tornehave, D., Jansen, P., Teisner, B., Rasmussen, H.B., Chemnitz, J., and Moscoso, G. (1993) Fetal antigen 1 (FA1) in the human pancreas: cell type expression, topological and quantitative variations during development. Anat. Embryol. (Berl.) 187, 335-341
    • (1993) Anat. Embryol. (Berl.) , vol.187 , pp. 335-341
    • Tornehave, D.1    Jansen, P.2    Teisner, B.3    Rasmussen, H.B.4    Chemnitz, J.5    Moscoso, G.6
  • 19
    • 0030457199 scopus 로고    scopus 로고
    • FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; Negative correlation with glucagon expression
    • Tornehave, D., Jensen, C.H., Teisner, B., and Larsson, L.I. (1996) FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; negative correlation with glucagon expression. Histochem. Cell Biol. 106, 535-542
    • (1996) Histochem. Cell Biol , vol.106 , pp. 535-542
    • Tornehave, D.1    Jensen, C.H.2    Teisner, B.3    Larsson, L.I.4
  • 20
    • 0027411983 scopus 로고
    • Studies on the isolation, structural analysis and tissue localization of fetal antigen 1 and its relation to a human adrenal-specific cDNA, pG2
    • Jensen, C.H., Teisner, B., Højrup, P., Rasmussen, H.B., Madsen, O.D., Nielsen, B., and Skjødt, K. (1993) Studies on the isolation, structural analysis and tissue localization of fetal antigen 1 and its relation to a human adrenal-specific cDNA, pG2. Hum. Reprod. 8, 635-641
    • (1993) Hum. Reprod , vol.8 , pp. 635-641
    • Jensen, C.H.1    Teisner, B.2    Højrup, P.3    Rasmussen, H.B.4    Madsen, O.D.5    Nielsen, B.6    Skjødt, K.7
  • 21
    • 0025415390 scopus 로고
    • Human neuroblastoma tumor cell lines correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts
    • Cooper, M.J., Hutchins, G.M., Cohen, P.S., Helman, L.J., Mennie, R.J., and Israel, M.A. (1990) Human neuroblastoma tumor cell lines correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts. Cell Growth Differ. 1, 149-159
    • (1990) Cell Growth Differ , vol.1 , pp. 149-159
    • Cooper, M.J.1    Hutchins, G.M.2    Cohen, P.S.3    Helman, L.J.4    Mennie, R.J.5    Israel, M.A.6
  • 22
    • 0026802012 scopus 로고
    • In vitro activation of distinct molecular and cellular phenotypes after induction of differentiation in a human neuroblastoma cell line
    • Gaetano, C, Matsumoto, K., and Thiele, C.J. (1992) In vitro activation of distinct molecular and cellular phenotypes after induction of differentiation in a human neuroblastoma cell line. Cancer Res. 52, 4402-4407
    • (1992) Cancer Res , vol.52 , pp. 4402-4407
    • Gaetano, C.1    Matsumoto, K.2    Thiele, C.J.3
  • 23
    • 18744366960 scopus 로고    scopus 로고
    • Differential expression of delta-like gene and protein in neuroblastoma, ganglioneuroblastoma and ganglioneuroma
    • Hsiao, C.C., Huang, C.C., Sheen, J.M., Tai, M.H., Chen, CM., Huang, L.L., and Chuang, J.H. (2005) Differential expression of delta-like gene and protein in neuroblastoma, ganglioneuroblastoma and ganglioneuroma. Mod. Pathol. 18, 656-662
    • (2005) Mod. Pathol , vol.18 , pp. 656-662
    • Hsiao, C.C.1    Huang, C.C.2    Sheen, J.M.3    Tai, M.H.4    Chen, C.M.5    Huang, L.L.6    Chuang, J.H.7
  • 25
    • 0032768431 scopus 로고    scopus 로고
    • Elevated serum levels of fetal antigen 1, a member of the epidermal growth factor superfamily, in patients with small cell lung cancer
    • Harken Jensen, C, Drivsholm, L., Laursen, I., and Teisner, B. (1999) Elevated serum levels of fetal antigen 1, a member of the epidermal growth factor superfamily, in patients with small cell lung cancer. Tumour Biol. 20, 256-262
    • (1999) Tumour Biol , vol.20 , pp. 256-262
    • Harken Jensen, C.1    Drivsholm, L.2    Laursen, I.3    Teisner, B.4
  • 28
    • 13244273748 scopus 로고    scopus 로고
    • Imprinting, expression, and localisation of DLK1 in Wilms tumours
    • Fukuzawa, R., Heathcott, R.W., Morison, I.M., and Reeve, A.E. (2005) Imprinting, expression, and localisation of DLK1 in Wilms tumours. J. Clin. Pathol. 58, 145-150
    • (2005) J. Clin. Pathol , vol.58 , pp. 145-150
    • Fukuzawa, R.1    Heathcott, R.W.2    Morison, I.M.3    Reeve, A.E.4
  • 29
    • 0037213389 scopus 로고    scopus 로고
    • The role of hep-atocytes and oval cells in liver regeneration and repopu-lation
    • Fausto, N. and Campbell, J.S. (2003) The role of hep-atocytes and oval cells in liver regeneration and repopu-lation. Mech. Dev. 120, 117-130
    • (2003) Mech. Dev , vol.120 , pp. 117-130
    • Fausto, N.1    Campbell, J.S.2
  • 30
    • 28444463613 scopus 로고    scopus 로고
    • Evidence regarding a stem cell origin of hepatocellular carcinoma
    • Shupe, T. and Petersen, B.E. (2005) Evidence regarding a stem cell origin of hepatocellular carcinoma. Stem Cell Rev. 1, 261-264
    • (2005) Stem Cell Rev , vol.1 , pp. 261-264
    • Shupe, T.1    Petersen, B.E.2
  • 32
    • 6044221204 scopus 로고    scopus 로고
    • Cancer stem cells in nervous system tumors
    • Singh, S.K., Clarke, I.D., Hide, T., and Dirks, P.B. (2004) Cancer stem cells in nervous system tumors. Oncogene 23, 7267-7273
    • (2004) Oncogene , vol.23 , pp. 7267-7273
    • Singh, S.K.1    Clarke, I.D.2    Hide, T.3    Dirks, P.B.4
  • 34
  • 36
    • 5444256238 scopus 로고    scopus 로고
    • Self-renewal and solid tumor stem cells
    • Al-Hajj, M. and Clarke, M.F. (2004) Self-renewal and solid tumor stem cells. Oncogene 23, 7274-7282
    • (2004) Oncogene , vol.23 , pp. 7274-7282
    • Al-Hajj, M.1    Clarke, M.F.2
  • 38
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien, C.A., Pollett, A., Gallinger, S., and Dick, J.E. (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445, 106-110
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 40
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collins, A.T., Berry, P.A., Hyde, C, Stower, M.J., and Maitland, N.J. (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res. 65, 10946-10951
    • (2005) Cancer Res , vol.65 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 41
    • 34249980343 scopus 로고    scopus 로고
    • Identification and characterization of tumorigenic liver cancer stem/progenitor cells
    • Ma, S., Chan, K.W., Hu, L., Lee, T.K., Wo, J.Y., Ng, I.O., Zheng, B.J., and Guan, X.Y. (2007) Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 132, 2542-2556
    • (2007) Gastroenterology , vol.132 , pp. 2542-2556
    • Ma, S.1    Chan, K.W.2    Hu, L.3    Lee, T.K.4    Wo, J.Y.5    Ng, I.O.6    Zheng, B.J.7    Guan, X.Y.8
  • 42
    • 41049114702 scopus 로고    scopus 로고
    • Delta-like protein (DLK) is a novel immunohistochemical marker for human hepatoblastomas
    • Dezso, K., Halasz, J., Bisgaard, H.C., Paku, S., Turanyi, E., Schaff, Z., and Nagy, P. (2008) Delta-like protein (DLK) is a novel immunohistochemical marker for human hepatoblastomas. Virchows Arch. 452, 443-448
    • (2008) Virchows Arch , vol.452 , pp. 443-448
    • Dezso, K.1    Halasz, J.2    Bisgaard, H.C.3    Paku, S.4    Turanyi, E.5    Schaff, Z.6    Nagy, P.7
  • 43
    • 0036929828 scopus 로고    scopus 로고
    • Hepatic progenitor cells in human liver diseases
    • Libbrecht, L. and Roskams, T. (2002) Hepatic progenitor cells in human liver diseases. Semin. Cell Dev. Biol. 13, 389-396
    • (2002) Semin. Cell Dev. Biol , vol.13 , pp. 389-396
    • Libbrecht, L.1    Roskams, T.2
  • 44
    • 0032964899 scopus 로고    scopus 로고
    • Oval cell numbers in human chronic liver diseases are directly related to disease severity
    • Lowes, K.N., Brennan, B.A., Yeoh, G.C., and Olynyk, J.K. (1999) Oval cell numbers in human chronic liver diseases are directly related to disease severity. Am. J. Pathol. 154, 537-541
    • (1999) Am. J. Pathol , vol.154 , pp. 537-541
    • Lowes, K.N.1    Brennan, B.A.2    Yeoh, G.C.3    Olynyk, J.K.4
  • 46
    • 34250361494 scopus 로고    scopus 로고
    • Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration
    • Jelnes, P., Santoni-Rugiu, E., Rasmussen, M., Friis, S.L., Nielsen, J.H., Tygstrup, N., and Bisgaard, H.C. (2007) Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration. Hepatology 45, 1462-1470
    • (2007) Hepatology , vol.45 , pp. 1462-1470
    • Jelnes, P.1    Santoni-Rugiu, E.2    Rasmussen, M.3    Friis, S.L.4    Nielsen, J.H.5    Tygstrup, N.6    Bisgaard, H.C.7
  • 49
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 51
    • 0346365362 scopus 로고    scopus 로고
    • Notch 1 signaling inhibits growth on human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis
    • Qi, R., An, H, Yu, Y., Zhang, M., Liu, S., Xu, H, Guo, Z., Cheng, T., and Cao, X. (2003) Notch 1 signaling inhibits growth on human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res. 63, 8323-8329
    • (2003) Cancer Res , vol.63 , pp. 8323-8329
    • Qi, R.1    An, H.2    Yu, Y.3    Zhang, M.4    Liu, S.5    Xu, H.6    Guo, Z.7    Cheng, T.8    Cao, X.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.