메뉴 건너뛰기




Volumn 91, Issue 7, 2013, Pages 486-489

Rapamycin and omega-1: MTOR-dependent and -independent Th2 skewing by human dendritic cells

Author keywords

dendritic cells; helminth; mammalian target of rapamycin; omega 1; rapamycin; T helper 2

Indexed keywords

ANTIGEN; GAMMA INTERFERON; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; OMEGA 1; RAPAMYCIN; S6 KINASE; SOLUBLE EGG ANTIGEN; UNCLASSIFIED DRUG;

EID: 84881477053     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.31     Document Type: Article
Times cited : (32)

References (27)
  • 1
    • 79151486083 scopus 로고    scopus 로고
    • Metabolism, migration and memory in cytotoxic T cells
    • Finlay D, Cantrell DA. Metabolism, migration and memory in cytotoxic T cells. Nat Rev Immunol 2011; 11: 109-117.
    • (2011) Nat Rev Immunol , vol.11 , pp. 109-117
    • Finlay, D.1    Cantrell, D.A.2
  • 2
    • 79151475165 scopus 로고    scopus 로고
    • Immunometabolism: An emerging frontier
    • Mathis D, Shoelson SE. Immunometabolism: an emerging frontier. Nat Rev Immunol 2011; 11: 81.
    • (2011) Nat Rev Immunol , vol.11 , pp. 81
    • Mathis, D.1    Shoelson, S.E.2
  • 3
    • 79960725910 scopus 로고    scopus 로고
    • The influence of mTOR on T helper cell differentiation and dendritic cell function
    • Salmond RJ, Zamoyska R. The influence of mTOR on T helper cell differentiation and dendritic cell function. Eur J Immunol 2011; 41: 2137-2141.
    • (2011) Eur J Immunol , vol.41 , pp. 2137-2141
    • Salmond, R.J.1    Zamoyska, R.2
  • 5
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012; 149: 274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 6
    • 84873056283 scopus 로고    scopus 로고
    • Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2
    • Ye L, Varamini B, Lamming DW, Sabatini DM, Baur JA. Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2. Front Genet 2012; 3: 177.
    • (2012) Front Genet , vol.3 , pp. 177
    • Ye, L.1    Varamini, B.2    Lamming, D.W.3    Sabatini, D.M.4    Baur, J.A.5
  • 8
    • 0036707521 scopus 로고    scopus 로고
    • PI3K-mediated negative feedback regulation of IL-12 production in DCs
    • Fukao T, Tanabe M, Terauchi Y, Ota T, Matsuda S, Asano T et al. PI3K-mediated negative feedback regulation of IL-12 production in DCs. Nat Immunol 2002; 3: 875-881.
    • (2002) Nat Immunol , vol.3 , pp. 875-881
    • Fukao, T.1    Tanabe, M.2    Terauchi, Y.3    Ota, T.4    Matsuda, S.5    Asano, T.6
  • 9
    • 0038036797 scopus 로고    scopus 로고
    • Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
    • DOI 10.1182/blood-2002-11-3370
    • Hackstein H, Taner T, Zahorchak AF, Morelli AE, Logar AJ, Gessner A et al. Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 2003; 101: 4457-4463. (Pubitemid 36857814)
    • (2003) Blood , vol.101 , Issue.11 , pp. 4457-4463
    • Hackstein, H.1    Taner, T.2    Zahorchak, A.F.3    Morelli, A.E.4    Logar, A.J.5    Gessner, A.6    Thomson, A.W.7
  • 10
    • 34249805413 scopus 로고    scopus 로고
    • + T regulatory cells and promote organ transplant tolerance
    • Turnquist HR, Raimondi G, Zahorchak AF, Fischer RT, Wang Z, Thomson AW. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4 + T cells, but enrich for antigen-specific Foxp3 + T regulatory cells and promote organ transplant tolerance. J Immunol 2007; 178: 7018-7031. (Pubitemid 46847428)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 7018-7031
    • Turnquist, H.R.1    Raimondi, G.2    Zahorchak, A.F.3    Fischer, R.T.4    Wang, Z.5    Thomson, A.W.6
  • 11
    • 77954748989 scopus 로고    scopus 로고
    • MTOR and GSK-3 shape the CD4 + T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS
    • Turnquist HR, Cardinal J, Macedo C, Rosborough BR, Sumpter TL, Geller DA et al. mTOR and GSK-3 shape the CD4 + T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS. Blood 2010; 115: 4758-4769.
    • (2010) Blood , vol.115 , pp. 4758-4769
    • Turnquist, H.R.1    Cardinal, J.2    MacEdo, C.3    Rosborough, B.R.4    Sumpter, T.L.5    Geller, D.A.6
  • 12
    • 79957583362 scopus 로고    scopus 로고
    • Evolution of Th2 immunity: A rapid repair response to tissue destructive pathogens
    • Allen JE, Wynn TA. Evolution of Th2 immunity: a rapid repair response to tissue destructive pathogens. PLoS Pathog 2011; 7: e1002003.
    • (2011) PLoS Pathog , vol.7
    • Allen, J.E.1    Wynn, T.A.2
  • 14
    • 84870262436 scopus 로고    scopus 로고
    • Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor
    • Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ et al. Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor. J Exp Med 2012; 209: S1.
    • (2012) J Exp Med , vol.209
    • Everts, B.1    Hussaarts, L.2    Driessen, N.N.3    Meevissen, M.H.4    Schramm, G.5    Van Der Ham, A.J.6
  • 15
    • 68149163162 scopus 로고    scopus 로고
    • The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)
    • Steinfelder S, Andersen JF, Cannons JL, Feng CG, Joshi M, Dwyer D et al. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med 2009; 206: 1681-1690.
    • (2009) J Exp Med , vol.206 , pp. 1681-1690
    • Steinfelder, S.1    Andersen, J.F.2    Cannons, J.L.3    Feng, C.G.4    Joshi, M.5    Dwyer, D.6
  • 16
    • 0348135024 scopus 로고    scopus 로고
    • Dendritic-cell control of pathogen-driven T-cell polarization
    • Kapsenberg ML. Dendritic-cell control of pathogen-driven T-cell polarization. Nat Rev Immunol 2003; 3: 984-993. (Pubitemid 37521540)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.12 , pp. 984-993
    • Kapsenberg, M.L.1
  • 17
  • 18
    • 80155142474 scopus 로고    scopus 로고
    • Rapamycin passes the torch: A new generation of mTOR inhibitors
    • Benjamin D, Colombi M, Moroni C, Hall MN. Rapamycin passes the torch: a new generation of mTOR inhibitors. Nat Rev Drug Discov 2011; 10: 868-880.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 868-880
    • Benjamin, D.1    Colombi, M.2    Moroni, C.3    Hall, M.N.4
  • 19
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induce T(H)2 and tolerogenic responses
    • Pulendran B, Tang H, Manicassamy S. Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat Immunol 2010; 11: 647-655.
    • (2010) Nat Immunol , vol.11 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 20
    • 77958126087 scopus 로고    scopus 로고
    • A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation
    • Haidinger M, Poglitsch M, Geyeregger R, Kasturi S, Zeyda M, Zlabinger GJ et al. A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. J Immunol 2010; 185: 3919-3931.
    • (2010) J Immunol , vol.185 , pp. 3919-3931
    • Haidinger, M.1    Poglitsch, M.2    Geyeregger, R.3    Kasturi, S.4    Zeyda, M.5    Zlabinger, G.J.6
  • 21
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • Trinchieri G. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 1994; 84: 4008-4027. (Pubitemid 24371902)
    • (1994) Blood , vol.84 , Issue.12 , pp. 4008-4027
    • Trinchieri, G.1
  • 22
    • 0035424854 scopus 로고    scopus 로고
    • Th1- and Th2-cell commitment during infectious disease: Asymmetry in divergent pathways
    • DOI 10.1016/S1471-4906(01)01975-5, PII S1471490601019755
    • Jankovic D, Liu Z, Gause WC. Th1-and Th2-cell commitment during infectious disease: asymmetry in divergent pathways. Trends Immunol 2001; 22: 450-457. (Pubitemid 32709980)
    • (2001) Trends in Immunology , vol.22 , Issue.8 , pp. 450-457
    • Jankovic, D.1    Liu, Z.2    Gause, W.C.3
  • 23
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012; 12: 265-277.
    • (2012) Nat Rev Cancer , vol.12 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 24
    • 56749096845 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells for autoimmune disease and transplantation
    • Thomson AW, Robbins PD. Tolerogenic dendritic cells for autoimmune disease and transplantation. Ann Rheum Dis 2008; 67 (Suppl 3), iii90-iii96.
    • (2008) Ann Rheum Dis , vol.67 , Issue.SUPPL. 3
    • Thomson, A.W.1    Robbins, P.D.2
  • 25
    • 0030068964 scopus 로고    scopus 로고
    • + cells after chemotherapy in human Schistosoma haematobium infection
    • DOI 10.1002/eji.1830260628
    • Grogan JL, Kremsner PG, Deelder AM, Yazdanbakhsh M. Elevated proliferation and interleukin-4 release from CD4 + cells after chemotherapy in human Schistosoma haematobium infection. Eur J Immunol 1996; 26: 1365-1370. (Pubitemid 26001074)
    • (1996) European Journal of Immunology , vol.26 , Issue.6 , pp. 1365-1370
    • Grogan, J.L.1    Kremsner, P.G.2    Deelder, A.M.3    Yazdanbakhsh, M.4
  • 26
    • 0025744455 scopus 로고
    • The purification, characterization, serological activity and hepatotoxic properties of two cationic glycoproteins (alpha 1 and omega 1) from Schistosoma mansoni eggs
    • Dunne DW, Jones FM, Doenhoff MJ. The purification, characterization, serological activity and hepatotoxic properties of two cationic glycoproteins (alpha 1 and omega 1) from Schistosoma mansoni eggs. Parasitology 1991; 103 (Pt 2), 225-236.
    • (1991) Parasitology , vol.103 , Issue.PART 2 , pp. 225-236
    • Dunne, D.W.1    Jones, F.M.2    Doenhoff, M.J.3
  • 27
    • 80051468764 scopus 로고    scopus 로고
    • Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells
    • Linssen MM, van Raalte DH, Toonen EJ, Alkema W, van der Zon GC, Dokter WH et al. Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells. Cell Signal 2011; 23: 1708-1715.
    • (2011) Cell Signal , vol.23 , pp. 1708-1715
    • Linssen, M.M.1    Van Raalte, D.H.2    Toonen, E.J.3    Alkema, W.4    Van Der Zon, G.C.5    Dokter, W.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.