DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation

EMBO Journal

Volumn 32, Issue 15, 2013, Pages 2172-2185

  Bétous, Rémy ^a,b   Pillaire, Marie Jeanne ^a,b   Pierini, Laura ^a,b   Van Der Laan, Siem ^c   Recolin, Bénédicte ^c,f   Ohl Séguy, Emma ^a,b   Guo, Caixia ^d   Niimi, Naoko ^e   Grúz, Petr ^e   Nohmi, Takehiko ^e   Friedberg, Errol ^d   Cazaux, Christophe ^a,b   Maiorano, Domenico ^c   Hoffmann, Jean Sébastien ^a,b  

^a CANCER RESEARCH CENTER OF TOULOUSE   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c INSTITUTE OF HUMAN GENETICS   (France)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^f UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

DNA polymerase ; genetic instability; replication checkpoint; replication stress

Indexed keywords

CHECKPOINT KINASE 1; DNA POLYMERASE;

ARTICLE; CELL CYCLE S PHASE; CELL PROLIFERATION; DNA DAMAGE CHECKPOINT; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE SILENCING; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; XENOPUS;

ANIMALS; CELL CYCLE PROTEINS; CELL PROLIFERATION; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GENOMIC INSTABILITY; HELA CELLS; HUMANS; PROTEIN KINASES; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 84881466184     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.148     Document Type: Article

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