-
1
-
-
46149087663
-
-
Global Strategy for Asthma Management and Prevention. Accessed February 12, 2013
-
Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma (GINA) 2012.GINA website. http://www.ginasthma.org/. Accessed February 12, 2013.
-
Global Initiative for Asthma (GINA) 2012
-
-
-
2
-
-
84858157489
-
The effect of environmental oxidative stress on airway inflammation
-
Auerbach A, Hernandez ML. The effect of environmental oxidative stress on airway inflammation. Curr Opin Allergy Clin Immunol. 2012; 12 (2): 133-139.
-
(2012)
Curr Opin Allergy Clin Immunol
, vol.12
, Issue.2
, pp. 133-139
-
-
Auerbach, A.1
Hernandez, M.L.2
-
3
-
-
84857045944
-
Asthma heterogeneity and therapeutic options from the clinic to the bench
-
Bonfield TL, Ross KR. Asthma heterogeneity and therapeutic options from the clinic to the bench. Curr Opin Allergy Clin Immunol. 2012; 12 (1): 60-67.
-
(2012)
Curr Opin Allergy Clin Immunol
, vol.12
, Issue.1
, pp. 60-67
-
-
Bonfield, T.L.1
Ross, K.R.2
-
4
-
-
32644453492
-
Gene by environment interactions and the development of asthma and allergy
-
Kabesch M. Gene by environment interactions and the development of asthma and allergy. Toxicol Lett. 2006; 162 (1): 43-48.
-
(2006)
Toxicol Lett
, vol.162
, Issue.1
, pp. 43-48
-
-
Kabesch, M.1
-
5
-
-
72149129743
-
The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke
-
Faux SP, Tai T, Thorne D, Xu Y, Breheny D, Gaca M. The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke. Biomarkers. 2009; 14(suppl 1): 90-96.
-
(2009)
Biomarkers
, vol.14
, Issue.SUPPL. 1
, pp. 90-96
-
-
Faux, S.P.1
Tai, T.2
Thorne, D.3
Xu, Y.4
Breheny, D.5
Gaca, M.6
-
6
-
-
1642534601
-
Perforin expression and cytotoxic activity of sputum CD8 1 lymphocytes in patients with COPD
-
Chrysofakis G, Tzanakis N, Kyriakoy D, et al. Perforin expression and cytotoxic activity of sputum CD8 1 lymphocytes in patients with COPD. Chest. 2004; 125 (1): 71-76.
-
(2004)
Chest
, vol.125
, Issue.1
, pp. 71-76
-
-
Chrysofakis, G.1
Tzanakis, N.2
Kyriakoy, D.3
-
7
-
-
84864425694
-
Response to infections in patients with asthma and atopic disease: An epiphenomenon or reflection of host susceptibility?
-
James KM, Peebles RS Jr, Hartert TV. Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility? J Allergy Clin Immunol. 2012; 130 (2): 343-351.
-
(2012)
J Allergy Clin Immunol
, vol.130
, Issue.2
, pp. 343-351
-
-
James, K.M.1
Peebles Jr., R.S.2
Hartert, T.V.3
-
8
-
-
84865000814
-
Innate type 2 cells and asthma
-
Hams E, Fallon PG. Innate type 2 cells and asthma. Curr Opin Pharmacol. 2012; 12 (4): 503-509.
-
(2012)
Curr Opin Pharmacol
, vol.12
, Issue.4
, pp. 503-509
-
-
Hams, E.1
Fallon, P.G.2
-
9
-
-
84859018336
-
Regulatory T cells in allergic asthma
-
Langier S, Sade K, Kivity S. Regulatory T cells in allergic asthma. Isr Med Assoc J. 2012; 14 (3): 180-183.
-
(2012)
Isr Med Assoc J.
, vol.14
, Issue.3
, pp. 180-183
-
-
Langier, S.1
Sade, K.2
Kivity, S.3
-
11
-
-
77951670553
-
Functional dissection of the granzyme family: Cell death and inflammation
-
Anthony DA, Andrews DM, Watt SV, Trapani JA, Smyth MJ. Functional dissection of the granzyme family: cell death and inflammation. Immunol Rev. 2010; 235 (1): 73-92.
-
(2010)
Immunol Rev
, vol.235
, Issue.1
, pp. 73-92
-
-
Anthony, D.A.1
Andrews, D.M.2
Watt, S.V.3
Trapani, J.A.4
Smyth, M.J.5
-
12
-
-
64549090599
-
The biology of cytotoxic cell granule exocytosis pathway: Granzymes have evolved to induce cell death and inflammation
-
Pardo J, Aguilo JI, Anel A, et al. The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation. Microbes Infect. 2009; 11 (4): 452-459.
-
(2009)
Microbes Infect
, vol.11
, Issue.4
, pp. 452-459
-
-
Pardo, J.1
Aguilo, J.I.2
Anel, A.3
-
13
-
-
52249097403
-
Natural killer cells in allergic inflammation
-
Erten G, Aktas E, Deniz G. Natural killer cells in allergic inflammation. Chem Immunol Allergy. 2008; 94: 48-57.
-
(2008)
Chem Immunol Allergy
, vol.94
, pp. 48-57
-
-
Erten, G.1
Aktas, E.2
Deniz, G.3
-
14
-
-
79961172459
-
Role of TNF superfamily ligands in innate immunity
-
Vujanovic NL. Role of TNF superfamily ligands in innate immunity. Immunol Res. 2011; 50 (2-3): 159-174.
-
(2011)
Immunol Res
, vol.50
, Issue.2-3
, pp. 159-174
-
-
Vujanovic, N.L.1
-
15
-
-
77951670713
-
Orphan granzymes find a home
-
Bovenschen N, Kummer JA. Orphan granzymes find a home. Immunol Rev. 2010; 235 (1): 117-127.
-
(2010)
Immunol Rev
, vol.235
, Issue.1
, pp. 117-127
-
-
Bovenschen, N.1
Kummer, J.A.2
-
16
-
-
1842552109
-
Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper
-
ATS/ERS Task Force
-
Celli BR, MacNee W; ATS/ERS Task Force. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 2004; 23 (6): 932-946.
-
(2004)
Eur Respir J.
, vol.23
, Issue.6
, pp. 932-946
-
-
Celli, B.R.1
MacNee, W.2
-
17
-
-
84859424158
-
Chronic obstructive pulmonary disease
-
Decramer M, Janssens W, Miravitlles M. Chronic obstructive pulmonary disease. Lancet. 2012; 379 (9823): 1341-1351.
-
(2012)
Lancet
, vol.379
, Issue.9823
, pp. 1341-1351
-
-
Decramer, M.1
Janssens, W.2
Miravitlles, M.3
-
18
-
-
70049084594
-
Decreased small airway and alveolar CD83 1 dendritic cells in COPD
-
Tsoumakidou M, Koutsopoulos AV, Tzanakis N, et al. Decreased small airway and alveolar CD83 1 dendritic cells in COPD. Chest. 2009; 136 (3): 726-733.
-
(2009)
Chest
, vol.136
, Issue.3
, pp. 726-733
-
-
Tsoumakidou, M.1
Koutsopoulos, A.V.2
Tzanakis, N.3
-
19
-
-
33845661834
-
Increased airway granzyme b and perforin in current and ex-smoking COPD subjects
-
Hodge S, Hodge G, Nairn J, Holmes M, Reynolds PN. Increased airway granzyme b and perforin in current and ex-smoking COPD subjects. COPD. 2006; 3 (4): 179-187.
-
(2006)
COPD
, vol.3
, Issue.4
, pp. 179-187
-
-
Hodge, S.1
Hodge, G.2
Nairn, J.3
Holmes, M.4
Reynolds, P.N.5
-
20
-
-
84860588926
-
Oxidative DNA damage and somatic mutations: A link to the molecular pathogenesis of chronic inflammatory airway diseases
-
Tzortzaki EG, Dimakou K, Neofytou E, et al. Oxidative DNA damage and somatic mutations: a link to the molecular pathogenesis of chronic inflammatory airway diseases. Chest. 2012; 141 (5): 1243-1250.
-
(2012)
Chest
, vol.141
, Issue.5
, pp. 1243-1250
-
-
Tzortzaki, E.G.1
Dimakou, K.2
Neofytou, E.3
-
21
-
-
79956366064
-
Unbalanced oxidant-induced DNA damage and repair in COPD: A link towards lung cancer
-
Caramori G, Adcock IM, Casolari P, et al. Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer. Thorax. 2011; 66 (6): 521-527.
-
(2011)
Thorax
, vol.66
, Issue.6
, pp. 521-527
-
-
Caramori, G.1
Adcock, I.M.2
Casolari, P.3
-
22
-
-
77956260373
-
Molecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary disease
-
Chung KF, Marwick JA. Molecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary disease. Ann N Y Acad Sci. 2010; 1203: 85-91.
-
(2010)
Ann N y Acad Sci
, vol.1203
, pp. 85-91
-
-
Chung, K.F.1
Marwick, J.A.2
-
23
-
-
0031912740
-
Airway inflammation in mild intermittent and in persistent asthma
-
Vignola AM, Chanez P, Campbell AM, et al. Airway inflammation in mild intermittent and in persistent asthma. Am J Respir Crit Care Med. 1998; 157 (2): 403-409.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, Issue.2
, pp. 403-409
-
-
Vignola, A.M.1
Chanez, P.2
Campbell, A.M.3
-
24
-
-
12144249965
-
Decline in lung function in the Busselton Health Study: The effects of asthma and cigarette smoking
-
James AL, Palmer LJ, Kicic E, et al. Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking. Am J Respir Crit Care Med. 2005; 171 (2): 109-114.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.2
, pp. 109-114
-
-
James, A.L.1
Palmer, L.J.2
Kicic, E.3
-
25
-
-
79951518607
-
Molecular targets of oxidative stress
-
Avery SV. Molecular targets of oxidative stress. Biochem J. 2011; 434 (2): 201-210.
-
(2011)
Biochem J.
, vol.434
, Issue.2
, pp. 201-210
-
-
Avery, S.V.1
-
26
-
-
33751264590
-
Differences in mic rosatellite DNA level between asthma and chronic obstruc tive pulmonary disease
-
Zervou MI, Tzortzaki EG, Makris D, et al. Differences in mic rosatellite DNA level between asthma and chronic obstruc tive pulmonary disease. Eur Respir J. 2006; 28 (3): 472-478.
-
(2006)
Eur Respir J.
, vol.28
, Issue.3
, pp. 472-478
-
-
Zervou, M.I.1
Tzortzaki, E.G.2
Makris, D.3
-
27
-
-
0346121625
-
Microsatellite DNA instability and loss of heterozygosity in bronchial asthma
-
Paraskakis E, Sourvinos G, Passam F, et al. Microsatellite DNA instability and loss of heterozygosity in bronchial asthma. Eur Respir J. 2003; 22 (6): 951-955.
-
(2003)
Eur Respir J.
, vol.22
, Issue.6
, pp. 951-955
-
-
Paraskakis, E.1
Sourvinos, G.2
Passam, F.3
-
28
-
-
58149384365
-
Microsatellite DNA instability and COPD exacerbations
-
Makris D, Tzanakis N, Damianaki A, et al. Microsatellite DNA instability and COPD exacerbations. Eur Respir J. 2008; 32 (3): 612-618.
-
(2008)
Eur Respir J.
, vol.32
, Issue.3
, pp. 612-618
-
-
Makris, D.1
Tzanakis, N.2
Damianaki, A.3
-
29
-
-
70349479415
-
Acquired somatic mutations in the microsatellite DNA, in children with bronchial asthma
-
Thomou C, Paraskakis E, Neofytou E, Kalmanti M, Siafakas NM, Tzortzaki EG. Acquired somatic mutations in the microsatellite DNA, in children with bronchial asthma. Pediatr Pulmonol. 2009; 44 (10): 1017-1024.
-
(2009)
Pediatr Pulmonol
, vol.44
, Issue.10
, pp. 1017-1024
-
-
Thomou, C.1
Paraskakis, E.2
Neofytou, E.3
Kalmanti, M.4
Siafakas, N.M.5
Tzortzaki, E.G.6
-
31
-
-
77953794345
-
The many paths to asthma: Phenotype shaped by innate and adaptive immunity
-
Kim HY, DeKruyff RH, Umetsu DT. The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol. 2010; 11 (7): 577-584.
-
(2010)
Nat Immunol
, vol.11
, Issue.7
, pp. 577-584
-
-
Kim, H.Y.1
Dekruyff, R.H.2
Umetsu, D.T.3
-
32
-
-
25644461000
-
Inflammatory process of CD8 1 CD28- T cells in induced sputum from asthmatic patients
-
Hamzaoui A, Chaouch N, Graïri H, Ammar J, Hamzaoui K. Inflammatory process of CD8 1 CD28- T cells in induced sputum from asthmatic patients. Mediators Inflamm. 2005; 2005 (3): 160-166.
-
(2005)
Mediators Inflamm
, vol.2005
, Issue.3
, pp. 160-166
-
-
Hamzaoui, A.1
Chaouch, N.2
Graïri, H.3
Ammar, J.4
Hamzaoui, K.5
-
33
-
-
25444522192
-
Bronchial CD8 cell infiltrate and lung function decline in asthma
-
AMPUL Study Group
-
van Rensen EL, Sont JK, Evertse CE, et al; AMPUL Study Group. Bronchial CD8 cell infiltrate and lung function decline in asthma. Am J Respir Crit Care Med. 2005; 172 (7): 837-841.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, Issue.7
, pp. 837-841
-
-
Van Rensen, E.L.1
Sont, J.K.2
Evertse, C.E.3
-
34
-
-
33847681925
-
Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease
-
Vernooy JH, Möller GM, van Suylen RJ, et al. Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007; 175 (5): 464-472.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, Issue.5
, pp. 464-472
-
-
Vernooy, J.H.1
Möller, G.M.2
Van Suylen, R.J.3
-
35
-
-
77953503076
-
Functional expression of granzyme B in human plasmacytoid dendritic cells: A role in allergic inflammation
-
Bratke K, Nielsen J, Manig F, et al. Functional expression of granzyme B in human plasmacytoid dendritic cells: a role in allergic inflammation. Clin Exp Allergy. 2010; 40(7): 1015-1024.
-
(2010)
Clin Exp Allergy
, vol.40
, Issue.7
, pp. 1015-1024
-
-
Bratke, K.1
Nielsen, J.2
Manig, F.3
-
36
-
-
0033137079
-
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
-
Beresford PJ, Xia Z, Greenberg AH, Lieberman J. Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity. 1999; 10 (5): 585-594.
-
(1999)
Immunity
, vol.10
, Issue.5
, pp. 585-594
-
-
Beresford, P.J.1
Xia, Z.2
Greenberg, A.H.3
Lieberman, J.4
-
37
-
-
0037423932
-
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
-
Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell. 2003; 112(5): 659-672.
-
(2003)
Cell
, vol.112
, Issue.5
, pp. 659-672
-
-
Fan, Z.1
Beresford, P.J.2
Oh, D.Y.3
Zhang, D.4
Lieberman, J.5
-
38
-
-
15244351845
-
Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis
-
Martinvalet D, Zhu P, Lieberman J. Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis. Immunity. 2005; 22 (3): 355-370.
-
(2005)
Immunity
, vol.22
, Issue.3
, pp. 355-370
-
-
Martinvalet, D.1
Zhu, P.2
Lieberman, J.3
-
39
-
-
0029844220
-
Nuclear transport of granzyme B (fragmentin-2). Dependence of perforin in vivo and cytosolic factors in vitro
-
Jans DA, Jans P, Briggs LJ, Sutton V, Trapani JA. Nuclear transport of granzyme B (fragmentin-2). Dependence of perforin in vivo and cytosolic factors in vitro. J Biol Chem. 1996; 271 (48): 30781-30789.
-
(1996)
J Biol Chem
, vol.271
, Issue.48
, pp. 30781-30789
-
-
Jans, D.A.1
Jans, P.2
Briggs, L.J.3
Sutton, V.4
Trapani, J.A.5
-
40
-
-
0030044052
-
Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis
-
Trapani JA, Browne KA, Smyth MJ, Jans DA. Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis. J Biol Chem. 1996; 271 (8): 4127-4133.
-
(1996)
J Biol Chem
, vol.271
, Issue.8
, pp. 4127-4133
-
-
Trapani, J.A.1
Browne, K.A.2
Smyth, M.J.3
Jans, D.A.4
|