MyD88 controls human metapneumovirus-induced pulmonary immune responses and disease pathogenesis

Virus Research

Volumn 176, Issue 1-2, 2013, Pages 241-250

  Ren, Junping ^a   Kolli, Deepthi ^a   Deng, Junfang ^a   Fang, Rong ^a   Gong, Bin ^a   Xue, Megan ^a   Casola, Antonella ^a,b   Garafalo, Roberto P ^a,b   Wang, Tian ^a   Bao, Xiaoyong ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Cytokines chemokines; HMPV; MyD88; Pulmonary immune response

Indexed keywords

BETA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MUCIN 5AC; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HOST RESISTANCE; HUMAN METAPNEUMOVIRUS; HUMAN METAPNEUMOVIRUS INFECTION; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; ISOLATED LUNG; LUNG INFECTION; LUNG LAVAGE; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; REGULATORY MECHANISM; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE;

HUMAN METAPNEUMOVIRUS; MUS;

EID: 84881375038     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2013.06.014     Document Type: Article

References (54)

1. Aderem A., Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature 2000, 406:782-787.
2. Akira S., Takeda K. Functions of toll-like receptors: lessons from KO mice. C. R. Biol. 2004, 327:581-589.
3. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
4. Alvarez R., Harrod K.S., Shieh W.J., Zaki S., Tripp R.A. Human metapneumovirus persists in BALB/c mice despite the presence of neutralizing antibodies. J. Virol. 2004, 78:14003-14011.
5. Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature 1998, 392:245-252.
6. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y.J., Pulendran B., Palucka K. Immunobiology of dendritic cells. Annu. Rev. Immunol. 2000, 18:767-811.
7. Banos-Lara M.D., Ghosh A., Guerrero-Plata A. Critical role of MDA5 in the interferon response induced by hMPV infection in dendritic cells and in vivo. J. Virol. 2012, 87(2):1242-1251.
8. Bao X., Liu T., Shan Y., Li K., Garofalo R.P., Casola A. Human metapneumovirus glycoprotein G inhibits innate immune responses. PLoS Pathog. 2008, 4:e1000077.
9. Bao X., Sinha M., Liu T., Hong C., Luxon B.A., Garofalo R.P., Casola A. Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis. Virology 2008, 374:114-127.
10. Beutler B. TNF, immunity and inflammatory disease: lessons of the past decade. J. Invest. Med. 1995, 43:227-235.
11. Bhoj V.G., Sun Q., Bhoj E.J., Somers C., Chen X., Torres J.P., Mejias A., Gomez A.M., Jafri H., Ramilo O., Chen Z.J. MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:14046-14051.
12. Castro S.M., Guerrero-Plata A., Suarez-Real G., Adegboyega P.A., Colasurdo G.N., Khan A.M., Garofalo R.P., Casola A. Antioxidant treatment ameliorates respiratory syncytial virus-induced disease and lung inflammation. Am. J. Respir. Crit. Care Med. 2006, 174:1361-1369.
13. Chakraborty K., Zhou Z., Wakamatsu N., Guerrero-Plata A. Interleukin-12p40 modulates human metapneumovirus-induced pulmonary disease in an acute mouse model of infection. PLoS ONE 2012, 7:e37173.
14. Crowe J.E., Williams J.V. Immunology of viral respiratory tract infection in infancy. Paediatr. Respir. Rev. 2003, 4:112-119.
15. Falsey A.R., Erdman D., Anderson L.J., Walsh E.E. Human metapneumovirus infections in young and elderly adults. J. Infect. Dis. 2003, 187:785-790.
16. Goutagny N., Jiang Z., Tian J., Parroche P., Schickli J., Monks B.G., Ulbrandt N., Ji H., Kiener P.A., Coyle A.J., Fitzgerald K.A. Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein. J. Immunol. 2010, 184:1168-1179.
17. Guerrero-Plata A., Baron S., Poast J.S., Adegboyega P.A., Casola A., Garofalo R.P. Activity and regulation of alpha interferon in respiratory syncytial virus and human metapneumovirus experimental infections. J. Virol. 2005, 79:10190-10199.
18. Guerrero-Plata A., Casola A., Garofalo R.P. Human metapneumovirus induces a profile of lung cytokines distinct from that of respiratory syncytial virus. J. Virol. 2005, 79:14992-14997.
19. Guerrero-Plata A., Casola A., Suarez G., Yu X., Spetch L., Peeples M.E., Garofalo R.P. Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus. Am. J. Respir. Cell Mol. Biol. 2006, 34:320-329.
20. Guerrero-Plata A., Kolli D., Hong C., Casola A., Garofalo R.P. Subversion of pulmonary dendritic cell function by paramyxovirus infections. J. Immunol. 2009, 182:3072-3083.
21. Hamelin M.E., Prince G.A., Gomez A.M., Kinkead R., Boivin G. Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice. J. Infect. Dis. 2006, 193:1634-1642.
22. Hamelmann E., Schwarze J., Takeda K., Oshiba A., Larsen G.L., Irvin C.G., Gelfand E.W. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am. J. Respir. Crit. Care Med. 1997, 156:766-775.
23. Hartmann E., Graefe H., Hopert A., Pries R., Rothenfusser S., Poeck H., Mack B., Endres S., Hartmann G., Wollenberg B. Analysis of plasmacytoid and myeloid dendritic cells in nasal epithelium. Clin. Vaccine Immunol. 2006, 13:1278-1286.
24. Hashimoto K., Graham B.S., Ho S.B., Adler K.B., Collins R.D., Olson S.J., Zhou W., Suzutani T., Jones P.W., Goleniewska K., O'Neal J.F., Peebles R.S. Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5. Am. J. Respir. Crit. Care Med. 2004, 170:306-312.
25. Herd K.A., Mahalingam S., Mackay I.M., Nissen M., Sloots T.P., Tindle R.W. Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice. J. Virol. 2006, 80:2034-2044.
26. Isnardi I., Ng Y.S., Srdanovic I., Motaghedi R., Rudchenko S., von B.H., Zhang S.Y., Puel A., Jouanguy E., Picard C., Garty B.Z., Camcioglu Y., Doffinger R., Kumararatne D., Davies G., Gallin J.I., Haraguchi S., Day N.K., Casanova J.L., Meffre E. IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity 2008, 29:746-757.
27. Ren J., Wang Q., Kolli D., Prusak D.J., Tseng C.-T.K., Chen Z.J., Li K., Wood T.G., Bao X. Human metapneumovirus M2-2 protein inhibits the innate cellular signaling by targeting MAVS. J. Virol. 2012, 86(23):13049-13061.
28. Kawai T., Akira S. Toll-like receptor downstream signaling. Arthritis Res. Ther. 2005, 7:12-19.
29. Kawai T., Akira S. Innate immune recognition of viral infection. Nat. Immunol. 2006, 7:131-137.
30. Kawai T., Akira S. TLR signaling. Cell Death Differ. 2006, 13(5):816-825.
31. Kolli D., Bao X., Liu T., Hong C., Wang T., Garofalo R.P., Casola A. Human metapneumovirus glycoprotein G inhibits TLR4-dependent signaling in monocyte-derived dendritic cells. J. Immunol. 2011, 187:47-54.
32. Kolli D., Bataki E.L., Spetch L., Guerrero-Plata A., Jewell A.M., Piedra P.A., Milligan G.N., Garofalo R.P., Casola A. T lymphocytes contribute to antiviral immunity and pathogenesis in experimental human metapneumovirus infection. J. Virol. 2008, 82:8560-8569.
33. Li Y.P., Gottwein J.M., Scheel T.K., Jensen T.B., Bukh J. MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:4991-4996.
34. Liao S., Bao X., Liu T., Lai S., Li K., Garofalo R.P., Casola A. Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. J. Gen. Virol. 2008, 89:1978-1986.
35. Liew F.Y., Xu D., Brint E.K., O'Neill L.A. Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 2005, 5:446-458.
36. Lin S.C., Lo Y.C., Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 2010, 465:885-890.
37. Liu P., Jamaluddin M., Li K., Garofalo R.P., Casola A., Brasier A.R. Retinoic Acid-inducible gene I mediates early antiviral response and toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. J. Virol. 2007, 81:1401-1411.
38. McKenna K., Beignon A.S., Bhardwaj N. Plasmacytoid dendritic cells: linking innate and adaptive immunity. J. Virol. 2005, 79:17-27.
39. Morcillo E.J., Cortijo J. Mucus and MUC in asthma. Curr. Opin. Pulm. Med. 2006, 12:1-6.
40. Picard C., von B.H., Ghandil P., Chrabieh M., Levy O., Arkwright P.D., McDonald D., Geha R.S., Takada H., Krause J.C., Creech C.B., Ku C.L., Ehl S., Marodi L., Al-Muhsen S., Al-Hajjar S., Al-Ghonaium A., Day-Good N.K., Holland S.M., Gallin J.I., Chapel H., Speert D.P., Rodriguez-Gallego C., Colino E., Garty B.Z., Roifman C., Hara T., Yoshikawa H., Nonoyama S., Domachowske J., Issekutz A.C., Tang M., Smart J., Zitnik S.E., Hoarau C., Kumararatne D.S., Thrasher A.J., Davies E.G., Bethune C., Sirvent N., de R.D., Camcioglu Y., Vasconcelos J., Guedes M., Vitor A.B., Rodrigo C., Almazan F., Mendez M., Arostegui J.I., Alsina L., Fortuny C., Reichenbach J., Verbsky J.W., Bossuyt X., Doffinger R., Abel L., Puel A., Casanova J.L. Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore) 2010, 89:403-425.
41. Rudd B.D., Schaller M.A., Smit J.J., Kunkel S.L., Neupane R., Kelley L., Berlin A.A., Lukacs N.W. MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection. J. Immunol. 2007, 178:5820-5827.
42. Rutigliano J.A., Rock M.T., Johnson A.K., Crowe J.E., Graham B.S. Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus. Virology 2005, 337:335-343.
43. Skrzeczynska-Moncznik J., Wawro K., Stefanska A., Oleszycka E., Kulig P., Zabel B.A., Sulkowski M., Kapinska-Mrowiecka M., Czubak-Macugowska M., Butcher E.C., Cichy J. Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem. Biophys. Res. Commun. 2009, 380:323-327.
44. Song K.S., Kim H.J., Kim K., Lee J.G., Yoon J.H. Regulator of G-protein signaling 4 suppresses LPS-induced MUC5AC overproduction in the airway. Am. J. Respir. Cell Mol. Biol. 2009, 41:40-49.
45. Takeda K., Akira S. Toll-like receptors in innate immunity. Int. Immunol. 2005, 17:1-14.
46. van den Hoogen B.G., de Jong J.C., Groen J., Kuiken T., de Groot R., Fouchier R.A., Osterhaus A.D. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat. Med. 2001, 7:719-724.
47. van Schaik S.M., Enhorning G., Vargas I., Welliver R.C. Respiratory syncytial virus affects pulmonary function in BALB/c mice. J. Infect. Dis. 1998, 177:269-276.
48. Vicente D., Cilla G., Montes M., Perez-Trallero E. Human metapneumovirus and community-acquired respiratory illness in children. Emerg. Infect. Dis. 2003, 9:602-603.
49. von B.H., Picard C., Puel A., Casanova J.L. Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans. Eur. J. Immunol. 2012, 42:3126-3135.
50. Voynow J.A., Gendler S.J., Rose M.C. Regulation of mucin genes in chronic inflammatory airway diseases. Am. J. Respir. Cell Mol. Biol. 2006, 34:661-665.
51. Wang S., Welte T., McGargill M., Town T., Thompson J., Anderson J.F., Flavell R.A., Fikrig E., Hedrick S.M., Wang T. Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. J. Immunol. 2008, 181:2084-2091.
52. Wang S.Z., Bao Y.X., Rosenberger C.L., Tesfaigzi Y., Stark J.M., Harrod K.S. IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection. J. Immunol. 2004, 173:4040-4049.
53. Williams J.V., Wang C.K., Yang C.F., Tollefson S.J., House F.S., Heck J.M., Chu M., Brown J.B., Lintao L.D., Quinto J.D., Chu D., Spaete R.R., Edwards K.M., Wright P.F., Crowe J.E. The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience. J. Infect. Dis. 2006, 193:387-395.
54. Xu L.L., Warren M.K., Rose W.L., Gong W., Wang J.M. Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro. J. Leukoc. Biol. 1996, 60:365-371.