-
1
-
-
0000042464
-
Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs Eggs
-
Briggs R, King TJ. Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs Eggs. Proc Natl Acad Sci USA 1952; 38: 455-463.
-
(1952)
Proc Natl Acad Sci USA
, vol.38
, pp. 455-463
-
-
Briggs, R.1
King, T.J.2
-
2
-
-
0035797898
-
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
-
Tada M, Takahama Y, Abe K, Nakatsuji N, Tada T. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol 2001; 11: 1553-1558.
-
(2001)
Curr Biol
, vol.11
, pp. 1553-1558
-
-
Tada, M.1
Takahama, Y.2
Abe, K.3
Nakatsuji, N.4
Tada, T.5
-
3
-
-
33745632618
-
Nuclear reprogramming and pluripotency
-
Hochedlinger K, Jaenisch R. Nuclear reprogramming and pluripotency. Nature 2006; 441: 1061-1067.
-
(2006)
Nature
, vol.441
, pp. 1061-1067
-
-
Hochedlinger, K.1
Jaenisch, R.2
-
4
-
-
23944457397
-
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
Cowan CA, Atienza J, Melton DA, Eggan K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 2005; 309: 1369-1373.
-
(2005)
Science
, vol.309
, pp. 1369-1373
-
-
Cowan, C.A.1
Atienza, J.2
Melton, D.A.3
Eggan, K.4
-
5
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
6
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
7
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
8
-
-
0037227099
-
Multipotent cell lineages in early mouse development depend on SOX2 function
-
Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 2003; 17: 126-140.
-
(2003)
Genes Dev
, vol.17
, pp. 126-140
-
-
Avilion, A.A.1
Nicolis, S.K.2
Pevny, L.H.3
Perez, L.4
Vivian, N.5
Lovell, B.R.6
-
9
-
-
2142821474
-
Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human
-
Hart AH, Hartley L, Ibrahim M, Robb L. Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human. Dev Dyn 2004; 230: 187-198.
-
(2004)
Dev Dyn
, vol.230
, pp. 187-198
-
-
Hart, A.H.1
Hartley, L.2
Ibrahim, M.3
Robb, L.4
-
10
-
-
1042302747
-
Histone deacetylase activity is required for embryonic stem cell differentiation
-
Lee JH, Hart SR, Skalnik DG. Histone deacetylase activity is required for embryonic stem cell differentiation. Genesis 2004; 38: 32-38.
-
(2004)
Genesis
, vol.38
, pp. 32-38
-
-
Lee, J.H.1
Hart, S.R.2
Skalnik, D.G.3
-
11
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
-
12
-
-
0025666925
-
Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity
-
Nichols J, Evans EP, Smith AG. Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity. Development 1990; 110: 1341-1348.
-
(1990)
Development
, vol.110
, pp. 1341-1348
-
-
Nichols, J.1
Evans, E.P.2
Smith, A.G.3
-
13
-
-
0025291459
-
Oct-4: A germline-specific transcription factor mapping to the mouse t-complex
-
Scholer HR, Dressler GR, Balling R, Rohdewohld H, Gruss P. Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J 1990; 9: 2185-2195.
-
(1990)
EMBO J
, vol.9
, pp. 2185-2195
-
-
Scholer, H.R.1
Dressler, G.R.2
Balling, R.3
Rohdewohld, H.4
Gruss, P.5
-
14
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005; 122: 947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
-
15
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Loh YH, Wu Q, Chew JL, et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006; 38: 431-440.
-
(2006)
Nat Genet
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
-
16
-
-
33746773659
-
Dissecting self-renewal in stem cells with RNA interference
-
Ivanova N, Dobrin R, Lu R, et al. Dissecting self-renewal in stem cells with RNA interference. Nature 2006; 442: 533-538.
-
(2006)
Nature
, vol.442
, pp. 533-538
-
-
Ivanova, N.1
Dobrin, R.2
Lu, R.3
-
17
-
-
33646483183
-
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells
-
Pritsker M, Ford NR, Jenq HT, Lemischka IR. Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. Proc Natl Acad Sci USA 2006; 103: 6946-6951.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6946-6951
-
-
Pritsker, M.1
Ford, N.R.2
Jenq, H.T.3
Lemischka, I.R.4
-
18
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen X, Xu H, Yuan P, et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008; 133: 1106-1117.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
-
19
-
-
34147117905
-
Zfx controls the self-renewal of embryonic and hematopoietic stem cells
-
Galan-Caridad JM, Harel S, Arenzana TL, et al. Zfx controls the self-renewal of embryonic and hematopoietic stem cells. Cell 2007; 129: 345-357.
-
(2007)
Cell
, vol.129
, pp. 345-357
-
-
Galan-Caridad, J.M.1
Harel, S.2
Arenzana, T.L.3
-
20
-
-
16844364151
-
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
-
Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 2005; 132: 885-896.
-
(2005)
Development
, vol.132
, pp. 885-896
-
-
Cartwright, P.1
McLean, C.2
Sheppard, A.3
Rivett, D.4
Jones, K.5
Dalton, S.6
-
21
-
-
0030875352
-
Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells
-
Boeuf H, Hauss C, Graeve FD, Baran N, Kedinger C. Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells. J Cell Biol 1997; 138: 1207-1217.
-
(1997)
J Cell Biol
, vol.138
, pp. 1207-1217
-
-
Boeuf, H.1
Hauss, C.2
Graeve, F.D.3
Baran, N.4
Kedinger, C.5
-
22
-
-
11244281579
-
Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4
-
Li Y, McClintick J, Zhong L, Edenberg HJ, Yoder MC, Chan RJ. Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood 2005; 105: 635-637.
-
(2005)
Blood
, vol.105
, pp. 635-637
-
-
Li, Y.1
McClintick, J.2
Zhong, L.3
Edenberg, H.J.4
Yoder, M.C.5
Chan, R.J.6
-
23
-
-
0344845415
-
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
-
Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003; 115: 281-292.
-
(2003)
Cell
, vol.115
, pp. 281-292
-
-
Ying, Q.L.1
Nichols, J.2
Chambers, I.3
Smith, A.4
-
24
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao Y, Yin X, Qin H, et al. Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell 2008; 3: 475-479.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
-
25
-
-
0032797827
-
The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2
-
Nishimoto M, Fukushima A, Okuda A, Muramatsu M. The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2. Mol Cell Biol 1999; 19: 5453-5465.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5453-5465
-
-
Nishimoto, M.1
Fukushima, A.2
Okuda, A.3
Muramatsu, M.4
-
26
-
-
33750823408
-
Murine inner cell mass-derived lineages depend on Sall4 function
-
Elling U, Klasen C, Eisenberger T, Anlag K, Treier M. Murine inner cell mass-derived lineages depend on Sall4 function. Proc Natl Acad Sci USA 2006; 103: 16319-16324.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16319-16324
-
-
Elling, U.1
Klasen, C.2
Eisenberger, T.3
Anlag, K.4
Treier, M.5
-
27
-
-
33747747661
-
Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells
-
Wu Q, Chen X, Zhang J, et al. Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells. J Biol Chem 2006; 281: 24090-24094.
-
(2006)
J Biol Chem
, vol.281
, pp. 24090-24094
-
-
Wu, Q.1
Chen, X.2
Zhang, J.3
-
28
-
-
58149378334
-
Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells
-
Yang J, Chai L, Fowles TC, et al. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. Proc Natl Acad Sci USA 2008; 105: 19756-19761.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19756-19761
-
-
Yang, J.1
Chai, L.2
Fowles, T.C.3
-
29
-
-
66749125824
-
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts
-
Tsubooka N, Ichisaka T, Okita K, Takahashi K, Nakagawa M, Yamanaka S. Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts. Genes Cells 2009; 14: 683-694.
-
(2009)
Genes Cells
, vol.14
, pp. 683-694
-
-
Tsubooka, N.1
Ichisaka, T.2
Okita, K.3
Takahashi, K.4
Nakagawa, M.5
Yamanaka, S.6
-
30
-
-
52649136596
-
Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression
-
van den Berg DL, Zhang W, Yates A, et al. Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression. Mol Cell Biol 2008; 28: 5986-5995.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5986-5995
-
-
Van den, B.D.L.1
Zhang, W.2
Yates, A.3
-
31
-
-
58149104232
-
Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells
-
Zhang X, Zhang J, Wang T, Esteban MA, Pei D. Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells. J Biol Chem 2008; 283: 35825-35833.
-
(2008)
J Biol Chem
, vol.283
, pp. 35825-35833
-
-
Zhang, X.1
Zhang, J.2
Wang, T.3
Esteban, M.A.4
Pei, D.5
-
32
-
-
59649105969
-
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
-
Feng B, Jiang J, Kraus P, et al. Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb. Nat Cell Biol 2009; 11: 197-203.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 197-203
-
-
Feng, B.1
Jiang, J.2
Kraus, P.3
-
33
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M, Koyanagi M, Tanabe K, et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008; 26: 101-106.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
-
34
-
-
0034054503
-
Synergy of SF1 and RAR in activation of Oct-3/4 promoter
-
Barnea E, Bergman Y. Synergy of SF1 and RAR in activation of Oct-3/4 promoter. J Biol Chem 2000; 275: 6608-6619.
-
(2000)
J Biol Chem
, vol.275
, pp. 6608-6619
-
-
Barnea, E.1
Bergman, Y.2
-
35
-
-
0028821102
-
Dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:Retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells
-
Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y. A Dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol 1995; 15: 1034-1048.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1034-1048
-
-
Ben-Shushan, E.1
Sharir, H.2
Pikarsky, E.3
Bergman, Y.A.4
-
36
-
-
20244381404
-
Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development
-
Gu P, Goodwin B, Chung AC, et al. Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol 2005; 25: 3492-3505.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3492-3505
-
-
Gu, P.1
Goodwin, B.2
Chung, A.C.3
-
38
-
-
75349088911
-
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
Heng JC, Feng B, Han J, et al. The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell 2010; 6: 167-174.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.C.1
Feng, B.2
Han, J.3
-
39
-
-
33750524413
-
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase
-
Becker KA, Ghule PN, Therrien JA, et al. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J Cell Physiol 2006; 209: 883-893.
-
(2006)
J Cell Physiol
, vol.209
, pp. 883-893
-
-
Becker, K.A.1
Ghule, P.N.2
Therrien, J.A.3
-
40
-
-
0028157458
-
Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts
-
Savatier P, Huang S, Szekely L, Wiman KG, Samarut J. Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts. Oncogene 1994; 9: 809-818.
-
(1994)
Oncogene
, vol.9
, pp. 809-818
-
-
Savatier, P.1
Huang, S.2
Szekely, L.3
Wiman, K.G.4
Samarut, J.5
-
41
-
-
0030034110
-
Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells
-
Savatier P, Lapillonne H, van Grunsven LA, Rudkin BB, Samarut J. Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 1996; 12: 309-322.
-
(1996)
Oncogene
, vol.12
, pp. 309-322
-
-
Savatier, P.1
Lapillonne, H.2
van Grunsven, L.A.3
Rudkin, B.B.4
Samarut, J.5
-
42
-
-
0035189927
-
Embryo-derived stem cells: Of mice and men
-
Smith AG. Embryo-derived stem cells: of mice and men. Annu Rev Cell Dev Biol 2001; 17: 435-462.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 435-462
-
-
Smith, A.G.1
-
43
-
-
0023661324
-
Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice
-
Suda Y, Aizawa S, Hirai S, et al. Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice. EMBO J 1987; 6: 4055-4065.
-
(1987)
EMBO J
, vol.6
, pp. 4055-4065
-
-
Suda, Y.1
Aizawa, S.2
Hirai, S.3
-
44
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
-
Aladjem MI, Spike BT, Rodewald LW, et al. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr Biol 1998; 8: 145-155.
-
(1998)
Curr Biol
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
Spike, B.T.2
Rodewald, L.W.3
-
45
-
-
33744975288
-
Cell cycle features of primate embryonic stem cells
-
Fluckiger AC, Marcy G, Marchand M, et al. Cell cycle features of primate embryonic stem cells. Stem Cells 2006; 24: 547-556.
-
(2006)
Stem Cells
, vol.24
, pp. 547-556
-
-
Fluckiger, A.C.1
Marcy, G.2
Marchand, M.3
-
46
-
-
0036709213
-
Signalling, cell cycle and pluripotency in embryonic stem cells
-
Burdon T, Smith A, Savatier P. Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 2002; 12: 432-438.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 432-438
-
-
Burdon, T.1
Smith, A.2
Savatier, P.3
-
47
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li R, Liang J, Ni S, et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 2010; 7: 51-63.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
-
48
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen TS, Hanna J, Zhang X, et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 2008; 454: 49-55.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
-
49
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani P, Golipour A, David L, et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 2010; 7: 64-77.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
Golipour, A.2
David, L.3
-
50
-
-
39149115929
-
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
-
Stadtfeld M, Maherali N, Breault DT, Hochedlinger K. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2008; 2: 230-240.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 230-240
-
-
Stadtfeld, M.1
Maherali, N.2
Breault, D.T.3
Hochedlinger, K.4
-
52
-
-
0033214995
-
Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1)
-
Perez-Roger I, Kim SH, Griffiths B, Sewing A, Land H. Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). EMBO J 1999; 18: 5310-5320.
-
(1999)
EMBO J
, vol.18
, pp. 5310-5320
-
-
Perez-Roger, I.1
Kim, S.H.2
Griffiths, B.3
Sewing, A.4
Land, H.5
-
53
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
Hong H, Takahashi K, Ichisaka T, et al. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 2009; 460: 1132-1135.
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
-
54
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
Kawamura T, Suzuki J, Wang YV, et al. Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 2009; 460: 1140-1144.
-
(2009)
Nature
, vol.460
, pp. 1140-1144
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
-
55
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
Li H, Collado M, Villasante A, et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 2009; 460: 1136-1139.
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
-
56
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
Marion RM, Strati K, Li H, et al. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 2009; 460: 1149-1153.
-
(2009)
Nature
, vol.460
, pp. 1149-1153
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
-
57
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
Utikal J, Polo JM, Stadtfeld M, et al. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 2009; 460: 1145-1148.
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
-
58
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 1992; 69: 1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
59
-
-
22144489899
-
INK4a/ARF: A multifunctional tumor suppressor locus
-
Sharpless NE. INK4a/ARF: a multifunctional tumor suppressor locus. Mutat Res 2005; 576: 22-38.
-
(2005)
Mutat Res
, vol.576
, pp. 22-38
-
-
Sharpless, N.E.1
-
60
-
-
77949383744
-
Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1
-
Edel MJ, Menchon C, Menendez S, Consiglio A, Raya A, Izpisua Belmonte JC. Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. Genes Dev 2010; 24: 561-573.
-
(2010)
Genes Dev
, vol.24
, pp. 561-573
-
-
Edel, M.J.1
Menchon, C.2
Menendez, S.3
Consiglio, A.4
Raya, A.5
Izpisua, B.J.C.6
-
61
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
62
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
-
Pasquinelli AE, Reinhart BJ, Slack F, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 2000; 408: 86-89.
-
(2000)
Nature
, vol.408
, pp. 86-89
-
-
Pasquinelli, A.E.1
Reinhart, B.J.2
Slack, F.3
-
63
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
65
-
-
34547441263
-
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3 UTR
-
Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3 UTR. Proc Natl Acad Sci USA 2007; 104: 9667-9672.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 9667-9672
-
-
Lytle, J.R.1
Yario, T.A.2
Steitz, J.A.3
-
66
-
-
38349064711
-
MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1
-
Tay YM, Tam WL, Ang YS, et al. MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells 2008; 26: 17-29.
-
(2008)
Stem Cells
, vol.26
, pp. 17-29
-
-
Tay, Y.M.1
Tam, W.L.2
Ang, Y.S.3
-
67
-
-
34249076321
-
The regulation of genes and genomes by small RNAs
-
Ambros V, Chen X. The regulation of genes and genomes by small RNAs. Development 2007; 134: 1635-1641.
-
(2007)
Development
, vol.134
, pp. 1635-1641
-
-
Ambros, V.1
Chen, X.2
-
68
-
-
67349123973
-
Redefining microRNA targets
-
Seitz H. Redefining microRNA targets. Curr Biol 2009; 19: 870-873.
-
(2009)
Curr Biol
, vol.19
, pp. 870-873
-
-
Seitz, H.1
-
69
-
-
0033634943
-
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
-
Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 2000; 5: 659-669.
-
(2000)
Mol Cell
, vol.5
, pp. 659-669
-
-
Slack, F.J.1
Basson, M.2
Liu, Z.3
Ambros, V.4
Horvitz, H.R.5
Ruvkun, G.6
-
71
-
-
79960040020
-
MicroRNA in Cancer---The involvement of aberrant microRNA biogenesis regulatory pathways
-
Davis BN, Hata A. microRNA in Cancer---The involvement of aberrant microRNA biogenesis regulatory pathways. Genes Cancer 2011; 1: 1100-1114.
-
(2011)
Genes Cancer
, vol.1
, pp. 1100-1114
-
-
Davis, B.N.1
Hata, A.2
-
72
-
-
79956190689
-
MicroRNA profiling in cancer
-
Munker R, Calin GA. MicroRNA profiling in cancer. Clin Sci (Lond) 2011; 121: 141-158.
-
(2011)
Clin Sci (Lond)
, vol.121
, pp. 141-158
-
-
Munker, R.1
Calin, G.A.2
-
73
-
-
78751474118
-
Non-coding RNAs as regulators of embryogenesis
-
Pauli A, Rinn JL, Schier AF. Non-coding RNAs as regulators of embryogenesis. Nat Rev Genet 2011; 12: 136-149.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 136-149
-
-
Pauli, A.1
Rinn, J.L.2
Schier, A.F.3
-
74
-
-
79955411900
-
Small RNAs in early mammalian development: From gametes to gastrulation
-
Suh N, Blelloch R. Small RNAs in early mammalian development: from gametes to gastrulation. Development 2011; 138: 1653-1661.
-
(2011)
Development
, vol.138
, pp. 1653-1661
-
-
Suh, N.1
Blelloch, R.2
-
75
-
-
55049135859
-
MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries
-
Bar M, Wyman SK, Fritz BR, et al. MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells 2008; 26: 2496-2505.
-
(2008)
Stem Cells
, vol.26
, pp. 2496-2505
-
-
Bar, M.1
Wyman, S.K.2
Fritz, B.R.3
-
77
-
-
66149131037
-
Target identification of microRNAs expressed highly in human embryonic stem cells
-
Li SS, Yu SL, Kao LP, et al. Target identification of microRNAs expressed highly in human embryonic stem cells. J Cell Biochem 2009; 106: 1020-1030.
-
(2009)
J Cell Biochem
, vol.106
, pp. 1020-1030
-
-
Li, S.S.1
Yu, S.L.2
Kao, L.P.3
-
78
-
-
48449084118
-
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
-
Marson A, Levine SS, Cole MF, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008; 134: 521-533.
-
(2008)
Cell
, vol.134
, pp. 521-533
-
-
Marson, A.1
Levine, S.S.2
Cole, M.F.3
-
79
-
-
2942534403
-
Human embryonic stem cells express a unique set of microRNAs
-
Suh MR, Lee Y, Kim JY, et al. Human embryonic stem cells express a unique set of microRNAs. Dev Biol 2004; 270: 488-498.
-
(2004)
Dev Biol
, vol.270
, pp. 488-498
-
-
Suh, M.R.1
Lee, Y.2
Kim, J.Y.3
-
80
-
-
40949130398
-
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
-
Sinkkonen L, Hugenschmidt T, Berninger P, et al. MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat Struct Mol Biol 2008; 15: 259-267.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 259-267
-
-
Sinkkonen, L.1
Hugenschmidt, T.2
Berninger, P.3
-
81
-
-
56749091922
-
Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
-
Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 2008; 40: 1478-1483.
-
(2008)
Nat Genet
, vol.40
, pp. 1478-1483
-
-
Wang, Y.1
Baskerville, S.2
Shenoy, A.3
Babiarz, J.E.4
Baehner, L.5
Blelloch, R.6
-
82
-
-
66149160608
-
Embryonic stem cell-specific microRNAs promote induced pluripotency
-
Judson RL, Babiarz JE, Venere M, Blelloch R. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol 2009; 27: 459-461.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 459-461
-
-
Judson, R.L.1
Babiarz, J.E.2
Venere, M.3
Blelloch, R.4
-
83
-
-
52949125268
-
Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
-
Lin SL, Chang DC, Chang-Lin S, et al. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 2008; 14: 2115-2124.
-
(2008)
RNA
, vol.14
, pp. 2115-2124
-
-
Lin, S.L.1
Chang, D.C.2
Chang-Lin, S.3
-
84
-
-
78650196632
-
Regulation of somatic cell reprogramming through inducible mir-302 expression
-
Lin SL, Chang DC, Lin CH, Ying SY, Leu D, Wu DT. Regulation of somatic cell reprogramming through inducible mir-302 expression. Nucleic Acids Res 2011; 39: 1054-1065.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1054-1065
-
-
Lin, S.L.1
Chang, D.C.2
Lin, C.H.3
Ying, S.Y.4
Leu, D.5
Wu, D.T.6
-
85
-
-
34548291568
-
The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons
-
Sone M, Hayashi T, Tarui H, Agata K, Takeichi M, Nakagawa S. The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. J Cell Sci 2007; 120: 2498-2506.
-
(2007)
J Cell Sci
, vol.120
, pp. 2498-2506
-
-
Sone, M.1
Hayashi, T.2
Tarui, H.3
Agata, K.4
Takeichi, M.5
Nakagawa, S.6
-
86
-
-
38649114329
-
Specific expression of long noncoding RNAs in the mouse brain
-
Mercer TR, Dinger ME, Sunkin SM, Mehler MF, Mattick JS. Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci USA 2008; 105: 716-721.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 716-721
-
-
Mercer, T.R.1
Dinger, M.E.2
Sunkin, S.M.3
Mehler, M.F.4
Mattick, J.S.5
-
87
-
-
34250189924
-
Genome mapping and expression analyses of human intronic noncoding RNAs reveal tissue-specific patterns and enrichment in genes related to regulation of transcription
-
Nakaya HI, Amaral PP, Louro R, et al. Genome mapping and expression analyses of human intronic noncoding RNAs reveal tissue-specific patterns and enrichment in genes related to regulation of transcription. Genome Biol 2007; 8: R43.
-
(2007)
Genome Biol
, vol.8
-
-
Nakaya, H.I.1
Amaral, P.P.2
Louro, R.3
-
88
-
-
56949091456
-
Noncoding RNA in development
-
Amaral PP, Mattick JS. Noncoding RNA in development. Mamm Genome 2008; 19: 454-492.
-
(2008)
Mamm Genome
, vol.19
, pp. 454-492
-
-
Amaral, P.P.1
Mattick, J.S.2
-
89
-
-
75149163987
-
Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells
-
Sheik Mohamed J, Gaughwin PM, Lim B, Robson P, Lipovich L. Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA 2010; 16: 324-337.
-
(2010)
RNA
, vol.16
, pp. 324-337
-
-
Sheik, M.J.1
Gaughwin, P.M.2
Lim, B.3
Robson, P.4
Lipovich, L.5
-
90
-
-
50649118350
-
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation
-
Dinger ME, Amaral PP, Mercer TR, et al. Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Res 2008; 18: 1433-1445.
-
(2008)
Genome Res
, vol.18
, pp. 1433-1445
-
-
Dinger, M.E.1
Amaral, P.P.2
Mercer, T.R.3
-
91
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
-
Guttman M, Amit I, Garber M, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009; 458: 223-227.
-
(2009)
Nature
, vol.458
, pp. 223-227
-
-
Guttman, M.1
Amit, I.2
Garber, M.3
-
92
-
-
78649467088
-
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells
-
Loewer S, Cabili MN, Guttman M, et al. Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet 2010; 42: 1113-1117.
-
(2010)
Nat Genet
, vol.42
, pp. 1113-1117
-
-
Loewer, S.1
Cabili, M.N.2
Guttman, M.3
-
93
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
Rinn JL, Kertesz M, Wang JK, et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 2007; 129: 1311-1323.
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
-
94
-
-
55349109963
-
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
-
Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science 2008; 322: 750-756.
-
(2008)
Science
, vol.322
, pp. 750-756
-
-
Zhao, J.1
Sun, B.K.2
Erwin, J.A.3
Song, J.J.4
Lee, J.T.5
-
95
-
-
35148845584
-
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
-
Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol 2007; 25: 1177-1181.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1177-1181
-
-
Meissner, A.1
Wernig, M.2
Jaenisch, R.3
-
96
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
Huangfu D, Maehr R, Guo W, et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 2008; 26: 795-797.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
-
97
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
-
Huangfu D, Osafune K, Maehr R, et al. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol 2008; 26: 1269-1275.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
-
98
-
-
54949115497
-
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
-
Shi Y, Desponts C, Do JT, Hahm HS, Scholer HR, Ding S. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 2008; 3: 568-574.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 568-574
-
-
Shi, Y.1
Desponts, C.2
Do, J.T.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
99
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
Kubicek S, O'Sullivan RJ, August EM, et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell 2007; 25: 473-481.
-
(2007)
Mol Cell
, vol.25
, pp. 473-481
-
-
Kubicek, S.1
O'Sullivan, R.J.2
August, E.M.3
-
100
-
-
22244435605
-
Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases
-
Brueckner B, Garcia Boy R, Siedlecki P, et al. Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases. Cancer Res 2005; 65: 6305-6311.
-
(2005)
Cancer Res
, vol.65
, pp. 6305-6311
-
-
Brueckner, B.1
Garcia, B.R.2
Siedlecki, P.3
-
101
-
-
0020579260
-
Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels
-
Schramm M, Thomas G, Towart R, Franckowiak G. Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels. Nature 1983; 303: 535-537.
-
(1983)
Nature
, vol.303
, pp. 535-537
-
-
Schramm, M.1
Thomas, G.2
Towart, R.3
Franckowiak, G.4
-
102
-
-
73049112178
-
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
-
Esteban MA, Wang T, Qin B, et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 2010; 6: 71-79.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 71-79
-
-
Esteban, M.A.1
Wang, T.2
Qin, B.3
-
103
-
-
11144314914
-
The molecular basis of pluripotency in mouse embryonic stem cells
-
Chambers I. The molecular basis of pluripotency in mouse embryonic stem cells. Cloning Stem Cells 2004; 6: 386-391.
-
(2004)
Cloning Stem Cells
, vol.6
, pp. 386-391
-
-
Chambers, I.1
-
104
-
-
9144239955
-
Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
-
Paling NR, Wheadon H, Bone HK, Welham MJ. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. J Biol Chem 2004; 279: 48063-48070.
-
(2004)
J Biol Chem
, vol.279
, pp. 48063-48070
-
-
Paling, N.R.1
Wheadon, H.2
Bone, H.K.3
Welham, M.J.4
-
105
-
-
0032747233
-
Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells
-
Burdon T, Chambers I, Stracey C, Niwa H, Smith A. Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells. Cells Tissues Organs 1999; 165: 131-143.
-
(1999)
Cells Tissues Organs
, vol.165
, pp. 131-143
-
-
Burdon, T.1
Chambers, I.2
Stracey, C.3
Niwa, H.4
Smith, A.5
-
106
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying QL, Wray J, Nichols J, et al. The ground state of embryonic stem cell self-renewal. Nature 2008; 453: 519-523.
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
-
107
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10: 55-63.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
108
-
-
54949105021
-
Promotion of reprogramming to ground state pluripotency by signal inhibition
-
Silva J, Barrandon O, Nichols J, Kawaguchi J, Theunissen TW, Smith A. Promotion of reprogramming to ground state pluripotency by signal inhibition. PLoS Biol 2008; 6: e253.
-
(2008)
PLoS Biol
, vol.6
-
-
Silva, J.1
Barrandon, O.2
Nichols, J.3
Kawaguchi, J.4
Theunissen, T.W.5
Smith, A.6
-
109
-
-
70350536767
-
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog
-
Ichida JK, Blanchard J, Lam K, et al. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 2009; 5: 491-503.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
-
110
-
-
51149118892
-
Deciphering the function of canonical Wnt signals in development and disease: Conditional loss- and gain-of-function mutations of beta-catenin in mice
-
Grigoryan T, Wend P, Klaus A, Birchmeier W. Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev 2008; 22: 2308-2341.
-
(2008)
Genes Dev
, vol.22
, pp. 2308-2341
-
-
Grigoryan, T.1
Wend, P.2
Klaus, A.3
Birchmeier, W.4
-
112
-
-
79953001876
-
Combined Chemical Treatment Enables Oct4-Induced Reprogramming from Mouse Embryonic Fibroblasts
-
Epub ahead of print)
-
Yuan X, Wan H, Zhao X, Zhu S, Zhou Q, Ding S. Combined Chemical Treatment Enables Oct4-Induced Reprogramming from Mouse Embryonic Fibroblasts. Stem Cells 2011; (Epub ahead of print).
-
(2011)
Stem Cells
-
-
Yuan, X.1
Wan, H.2
Zhao, X.3
Zhu, S.4
Zhou, Q.5
Ding, S.6
-
113
-
-
78650915547
-
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules
-
Li Y, Zhang Q, Yin X, et al. Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Res 2011; 21: 196-204.
-
(2011)
Cell Res
, vol.21
, pp. 196-204
-
-
Li, Y.1
Zhang, Q.2
Yin, X.3
-
114
-
-
2642551574
-
Small molecule regulators of protein arginine methyltransferases
-
Cheng D, Yadav N, King RW, Swanson MS, Weinstein EJ, Bedford MT. Small molecule regulators of protein arginine methyltransferases. J Biol Chem 2004; 279: 23892-23899.
-
(2004)
J Biol Chem
, vol.279
, pp. 23892-23899
-
-
Cheng, D.1
Yadav, N.2
King, R.W.3
Swanson, M.S.4
Weinstein, E.J.5
Bedford, M.T.6
-
115
-
-
20844450998
-
Arginine methylation an emerging regulator of protein function
-
Bedford MT, Richard S. Arginine methylation an emerging regulator of protein function. Mol Cell 2005; 18: 263-272.
-
(2005)
Mol Cell
, vol.18
, pp. 263-272
-
-
Bedford, M.T.1
Richard, S.2
-
116
-
-
34848885467
-
Interplay between chromatin remodelers and protein arginine methyltransferases
-
Pal S, Sif S. Interplay between chromatin remodelers and protein arginine methyltransferases. J Cell Physiol 2007; 213: 306-315.
-
(2007)
J Cell Physiol
, vol.213
, pp. 306-315
-
-
Pal, S.1
Sif, S.2
-
117
-
-
67649968054
-
The protein arginine methyltransferase family: An update about function, new perspectives and the physiological role in humans
-
Wolf SS. The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans. Cell Mol Life Sci 2009; 66: 2109-2121.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2109-2121
-
-
Wolf, S.S.1
-
118
-
-
79953323442
-
Reprogramming of mouse and human somatic cells by high-performance engineered factors
-
Wang Y, Chen J, Hu JL, et al. Reprogramming of mouse and human somatic cells by high-performance engineered factors. EMBO Rep 2011; 12: 373-378.
-
(2011)
EMBO Rep
, vol.12
, pp. 373-378
-
-
Wang, Y.1
Chen, J.2
Hu, J.L.3
-
119
-
-
0037100658
-
Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex
-
Tomioka M, Nishimoto M, Miyagi S, et al. Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res 2002; 30: 3202-3213.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 3202-3213
-
-
Tomioka, M.1
Nishimoto, M.2
Miyagi, S.3
-
120
-
-
34548077820
-
Back to basics: Sox genes
-
Kiefer JC. Back to basics: Sox genes. Dev Dyn 2007; 236: 2356-2366.
-
(2007)
Dev Dyn
, vol.236
, pp. 2356-2366
-
-
Kiefer, J.C.1
-
121
-
-
34748830336
-
Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors
-
Lefebvre V, Dumitriu B, Penzo-Mendez A, Han Y, Pallavi B. Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors. Int J Biochem Cell Biol 2007; 39: 2195-2214.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 2195-2214
-
-
Lefebvre, V.1
Dumitriu, B.2
Penzo-Mendez, A.3
Han, Y.4
Pallavi, B.5
-
122
-
-
0036668285
-
Matching SOX: Partner proteins and co-factors of the SOX family of transcriptional regulators
-
Wilson M, Koopman P. Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Curr Opin Genet Dev 2002; 12: 441-446.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 441-446
-
-
Wilson, M.1
Koopman, P.2
-
123
-
-
69949118280
-
Interplay of Oct4 with Sox2 and Sox17: A molecular switch from stem cell pluripotency to specifying a cardiac fate
-
Stefanovic S, Abboud N, Desilets S, Nury D, Cowan C, Puceat M. Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate. J Cell Biol 2009; 186: 665-673.
-
(2009)
J Cell Biol
, vol.186
, pp. 665-673
-
-
Stefanovic, S.1
Abboud, N.2
Desilets, S.3
Nury, D.4
Cowan, C.5
Puceat, M.6
-
124
-
-
79957592228
-
Conversion of Sox17 into a Pluripotency Reprogramming Factor by re-engineering its Association with Oct4 on DNA
-
Jauch R, Aksoy I, Hutchins AP, et al. Conversion of Sox17 into a Pluripotency Reprogramming Factor by re-engineering its Association with Oct4 on DNA. Stem Cells 2011; 29: 940-951.
-
(2011)
Stem Cells
, vol.29
, pp. 940-951
-
-
Jauch, R.1
Aksoy, I.2
Hutchins, A.P.3
-
125
-
-
84875940444
-
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm
-
Aksoy I, Jauch R, Chen J, et al. Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm. EMBO J 2013; 32(7): 938-953.
-
(2013)
EMBO J
, vol.32
, Issue.7
, pp. 938-953
-
-
Aksoy, I.1
Jauch, R.2
Chen, J.3
-
126
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L, Manos PD, Ahfeldt T, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010; 7: 618-630.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
-
127
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou H, Wu S, Joo JY, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009; 4: 381-384.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
-
128
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
Brennand KJ, Simone A, Jou J, et al. Modelling schizophrenia using human induced pluripotent stem cells. Nature 2011; 473: 221-225.
-
(2011)
Nature
, vol.473
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
-
129
-
-
79955602167
-
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
-
Cheung AY, Horvath LM, Grafodatskaya D, et al. Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Hum Mol Genet 2011; 20: 2103-2115.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2103-2115
-
-
Cheung, A.Y.1
Horvath, L.M.2
Grafodatskaya, D.3
-
130
-
-
78149488365
-
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto MC, Carromeu C, Acab A, et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 2010; 143: 527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
Carromeu, C.2
Acab, A.3
|