메뉴 건너뛰기




Volumn 23, Issue 3, 2013, Pages 381-392

Proton Magnetic Resonance Spectroscopy: Technique for the Neuroradiologist

Author keywords

Chemical shift; Localization; Metabolite; Shimming; Spectral dispersion; Suppression

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; ACETYL COENZYME A; ACETYLCHOLINE; ALANINE; ASPARTIC ACID; ASPARTOACYLASE; CHOLINE; CITICOLINE; CREATINE; CREATINE PHOSPHATE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; LACTIC ACID; LIPID; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHOSPHORYLCHOLINE;

EID: 84881344488     PISSN: 10525149     EISSN: 15579867     Source Type: Journal    
DOI: 10.1016/j.nic.2012.10.003     Document Type: Review
Times cited : (41)

References (49)
  • 1
    • 0036734551 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in the brain: report of AAPM MR Task Group #9
    • Drost D.J., Riddle W.R., Clarke G.D. Proton magnetic resonance spectroscopy in the brain: report of AAPM MR Task Group #9. Med Phys 2002, 29(9):2177-2197.
    • (2002) Med Phys , vol.29 , Issue.9 , pp. 2177-2197
    • Drost, D.J.1    Riddle, W.R.2    Clarke, G.D.3
  • 2
    • 79955643839 scopus 로고    scopus 로고
    • MR spectroscopy and spectroscopic imaging of the brain
    • Zhu H., Barker P.B. MR spectroscopy and spectroscopic imaging of the brain. Methods Mol Biol 2011, 711:203-226.
    • (2011) Methods Mol Biol , vol.711 , pp. 203-226
    • Zhu, H.1    Barker, P.B.2
  • 3
    • 0242552284 scopus 로고    scopus 로고
    • High-field proton MRS of human brain
    • Di Costanzo A., Trojsi F., Tosetti M., et al. High-field proton MRS of human brain. Eur J Radiol 2003, 48(2):146-153.
    • (2003) Eur J Radiol , vol.48 , Issue.2 , pp. 146-153
    • Di Costanzo, A.1    Trojsi, F.2    Tosetti, M.3
  • 4
    • 56849086068 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy in neurological diagnosis
    • xiii
    • Tran T., Ross B., Lin A. Magnetic resonance spectroscopy in neurological diagnosis. Neurol Clin 2009, 27(1):21-60. xiii.
    • (2009) Neurol Clin , vol.27 , Issue.1 , pp. 21-60
    • Tran, T.1    Ross, B.2    Lin, A.3
  • 5
    • 2042469484 scopus 로고    scopus 로고
    • Acomparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain
    • Srinivasan R., Vigneron D., Sailasuta N., et al. Acomparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain. Magn Reson Imaging 2004, 22(4):523-528.
    • (2004) Magn Reson Imaging , vol.22 , Issue.4 , pp. 523-528
    • Srinivasan, R.1    Vigneron, D.2    Sailasuta, N.3
  • 6
    • 5044228017 scopus 로고    scopus 로고
    • Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts
    • Kreis R. Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts. NMR Biomed 2004, 17(6):361-381.
    • (2004) NMR Biomed , vol.17 , Issue.6 , pp. 361-381
    • Kreis, R.1
  • 7
    • 0028814635 scopus 로고
    • Anomalous transverse relaxation in 1H spectroscopy in human brain at 4 Tesla
    • Posse S., Cuenod C.A., Risinger R., et al. Anomalous transverse relaxation in 1H spectroscopy in human brain at 4 Tesla. Magn Reson Med 1995, 33(2):246-252.
    • (1995) Magn Reson Med , vol.33 , Issue.2 , pp. 246-252
    • Posse, S.1    Cuenod, C.A.2    Risinger, R.3
  • 8
    • 0027946439 scopus 로고
    • Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T
    • Hetherington H.P., Mason G.F., Pan J.W., et al. Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T. Magn Reson Med 1994, 32(5):565-571.
    • (1994) Magn Reson Med , vol.32 , Issue.5 , pp. 565-571
    • Hetherington, H.P.1    Mason, G.F.2    Pan, J.W.3
  • 9
    • 0035033720 scopus 로고    scopus 로고
    • Single-voxel proton MRS of the human brain at 1.5T and 3.0T
    • Barker P.B., Hearshen D.O., Boska M.D. Single-voxel proton MRS of the human brain at 1.5T and 3.0T. Magn Reson Med 2001, 45(5):765-769.
    • (2001) Magn Reson Med , vol.45 , Issue.5 , pp. 765-769
    • Barker, P.B.1    Hearshen, D.O.2    Boska, M.D.3
  • 10
    • 0033865461 scopus 로고    scopus 로고
    • Comparison of the quantification precision of human short echo time (1)H spectroscopy at 1.5 and 4.0 Tesla
    • Bartha R., Drost D.J., Menon R.S., et al. Comparison of the quantification precision of human short echo time (1)H spectroscopy at 1.5 and 4.0 Tesla. Magn Reson Med 2000, 44(2):185-192.
    • (2000) Magn Reson Med , vol.44 , Issue.2 , pp. 185-192
    • Bartha, R.1    Drost, D.J.2    Menon, R.S.3
  • 11
    • 0027200329 scopus 로고
    • Automatic, localized invivo adjustment of all first- and second-order shim coils
    • Gruetter R. Automatic, localized invivo adjustment of all first- and second-order shim coils. Magn Reson Med 1993, 29(6):804-811.
    • (1993) Magn Reson Med , vol.29 , Issue.6 , pp. 804-811
    • Gruetter, R.1
  • 12
    • 0021894409 scopus 로고
    • 1H NMR chemical shift selective (CHESS) imaging
    • Haase A., Frahm J., Hanicke W., et al. 1H NMR chemical shift selective (CHESS) imaging. Phys Med Biol 1985, 30(4):341-344.
    • (1985) Phys Med Biol , vol.30 , Issue.4 , pp. 341-344
    • Haase, A.1    Frahm, J.2    Hanicke, W.3
  • 13
    • 0028434775 scopus 로고
    • WET, a T1- and B1-insensitive water-suppression method for invivo localized 1H NMR spectroscopy
    • Ogg R.J., Kingsley P.B., Taylor J.S. WET, a T1- and B1-insensitive water-suppression method for invivo localized 1H NMR spectroscopy. JMagn Reson B 1994, 104(1):1-10.
    • (1994) JMagn Reson B , vol.104 , Issue.1 , pp. 1-10
    • Ogg, R.J.1    Kingsley, P.B.2    Taylor, J.S.3
  • 14
    • 0032588957 scopus 로고    scopus 로고
    • Invivo 1H NMR spectroscopy of rat brain at 1 ms echo time
    • Tkac I., Starcuk Z., Choi I.Y., et al. Invivo 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn Reson Med 1999, 41(4):649-656.
    • (1999) Magn Reson Med , vol.41 , Issue.4 , pp. 649-656
    • Tkac, I.1    Starcuk, Z.2    Choi, I.Y.3
  • 15
    • 0027247645 scopus 로고
    • Multisection proton MR spectroscopic imaging of the brain
    • Duyn J.H., Gillen J., Sobering G., et al. Multisection proton MR spectroscopic imaging of the brain. Radiology 1993, 188(1):277-282.
    • (1993) Radiology , vol.188 , Issue.1 , pp. 277-282
    • Duyn, J.H.1    Gillen, J.2    Sobering, G.3
  • 16
    • 0033970816 scopus 로고    scopus 로고
    • Very selective suppression pulses for clinical MRSI studies of brain and prostate cancer
    • Tran T.K., Vigneron D.B., Sailasuta N., et al. Very selective suppression pulses for clinical MRSI studies of brain and prostate cancer. Magn Reson Med 2000, 43(1):23-33.
    • (2000) Magn Reson Med , vol.43 , Issue.1 , pp. 23-33
    • Tran, T.K.1    Vigneron, D.B.2    Sailasuta, N.3
  • 17
    • 62649108296 scopus 로고    scopus 로고
    • Design of cosine modulated very selective suppression pulses for MR spectroscopic imaging at 3T
    • Osorio J.A., Xu D., Cunningham C.H., et al. Design of cosine modulated very selective suppression pulses for MR spectroscopic imaging at 3T. Magn Reson Med 2009, 61(3):533-540.
    • (2009) Magn Reson Med , vol.61 , Issue.3 , pp. 533-540
    • Osorio, J.A.1    Xu, D.2    Cunningham, C.H.3
  • 19
    • 19944421821 scopus 로고    scopus 로고
    • Spectral analysis of multichannel MRS data
    • Sandgren N., Stoica P., Frigo F.J., et al. Spectral analysis of multichannel MRS data. JMagn Reson 2005, 175(1):79-91.
    • (2005) JMagn Reson , vol.175 , Issue.1 , pp. 79-91
    • Sandgren, N.1    Stoica, P.2    Frigo, F.J.3
  • 20
    • 0034959727 scopus 로고    scopus 로고
    • Automatic quantitation of localized invivo 1H spectra with LCModel
    • Provencher S.W. Automatic quantitation of localized invivo 1H spectra with LCModel. NMR Biomed 2001, 14(4):260-264.
    • (2001) NMR Biomed , vol.14 , Issue.4 , pp. 260-264
    • Provencher, S.W.1
  • 21
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized invivo proton NMR spectra
    • Provencher S.W. Estimation of metabolite concentrations from localized invivo proton NMR spectra. Magn Reson Med 1993, 30(6):672-679.
    • (1993) Magn Reson Med , vol.30 , Issue.6 , pp. 672-679
    • Provencher, S.W.1
  • 22
    • 0034989141 scopus 로고    scopus 로고
    • Java-based graphical user interface for the MRUI quantitation package
    • Naressi A., Couturier C., Devos J.M., et al. Java-based graphical user interface for the MRUI quantitation package. MAGMA 2001, 12(2-3):141-152.
    • (2001) MAGMA , vol.12 , Issue.2-3 , pp. 141-152
    • Naressi, A.1    Couturier, C.2    Devos, J.M.3
  • 23
    • 0035033455 scopus 로고    scopus 로고
    • Java-based graphical user interface for MRUI, a software package for quantitation of invivo/medical magnetic resonance spectroscopy signals
    • Naressi A., Couturier C., Castang I., et al. Java-based graphical user interface for MRUI, a software package for quantitation of invivo/medical magnetic resonance spectroscopy signals. Comput Biol Med 2001, 31(4):269-286.
    • (2001) Comput Biol Med , vol.31 , Issue.4 , pp. 269-286
    • Naressi, A.1    Couturier, C.2    Castang, I.3
  • 24
    • 0030853518 scopus 로고    scopus 로고
    • Anew method for absolute quantitation of MRS metabolites
    • Barantin L., Le Pape A., Akoka S. Anew method for absolute quantitation of MRS metabolites. Magn Reson Med 1997, 38(2):179-182.
    • (1997) Magn Reson Med , vol.38 , Issue.2 , pp. 179-182
    • Barantin, L.1    Le Pape, A.2    Akoka, S.3
  • 25
    • 0029312360 scopus 로고
    • Invivo quantitation of metabolite concentrations in the brain by means of proton MRS
    • Henriksen O. Invivo quantitation of metabolite concentrations in the brain by means of proton MRS. NMR Biomed 1995, 8(4):139-148.
    • (1995) NMR Biomed , vol.8 , Issue.4 , pp. 139-148
    • Henriksen, O.1
  • 26
    • 0030050039 scopus 로고    scopus 로고
    • Quantitative proton MR spectroscopic imaging of the human brain
    • Soher B.J., van Zijl P.C., Duyn J.H., et al. Quantitative proton MR spectroscopic imaging of the human brain. Magn Reson Med 1996, 35(3):356-363.
    • (1996) Magn Reson Med , vol.35 , Issue.3 , pp. 356-363
    • Soher, B.J.1    van Zijl, P.C.2    Duyn, J.H.3
  • 27
    • 0030846501 scopus 로고    scopus 로고
    • Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS
    • Pouwels P.J., Frahm J. Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS. NMR Biomed 1997, 10:73-78.
    • (1997) NMR Biomed , vol.10 , pp. 73-78
    • Pouwels, P.J.1    Frahm, J.2
  • 28
    • 0023818297 scopus 로고
    • Aspartoacylase deficiency and N-acetylaspartic aciduria in patients with Canavan disease
    • Matalon R., Michals K., Sebesta D., et al. Aspartoacylase deficiency and N-acetylaspartic aciduria in patients with Canavan disease. Am J Med Genet 1988, 29(2):463-471.
    • (1988) Am J Med Genet , vol.29 , Issue.2 , pp. 463-471
    • Matalon, R.1    Michals, K.2    Sebesta, D.3
  • 29
    • 77049248952 scopus 로고
    • N-acetyl-L-aspartic acid in brain
    • Tallan H.H., Moore S., Stein W.H. N-acetyl-L-aspartic acid in brain. JBiol Chem 1956, 219:257-264.
    • (1956) JBiol Chem , vol.219 , pp. 257-264
    • Tallan, H.H.1    Moore, S.2    Stein, W.H.3
  • 30
    • 0000356642 scopus 로고
    • Studies on the distribution of N-acetyl-L-aspartic acid in brain
    • Tallan H.H. Studies on the distribution of N-acetyl-L-aspartic acid in brain. JBiol Chem 1956, 224:41-45.
    • (1956) JBiol Chem , vol.224 , pp. 41-45
    • Tallan, H.H.1
  • 31
    • 0014286698 scopus 로고
    • Acetyl transport mechanisms. Metabolism of N-acetyl-L-aspartic acid in the non-nervous tissues of the rat
    • Benuck M., D'Adamo J.A. Acetyl transport mechanisms. Metabolism of N-acetyl-L-aspartic acid in the non-nervous tissues of the rat. Biochim Biophys Acta 1968, 152(3):611-618.
    • (1968) Biochim Biophys Acta , vol.152 , Issue.3 , pp. 611-618
    • Benuck, M.1    D'Adamo, J.A.2
  • 32
    • 0015611504 scopus 로고
    • The occurrence of N-acetylaspartate amidohydrolase (Aminoacylase II) in the developing rat
    • D'Adamo A.F., Smith J.C., Woiler C. The occurrence of N-acetylaspartate amidohydrolase (Aminoacylase II) in the developing rat. JNeurochem 1973, 20:1275-1278.
    • (1973) JNeurochem , vol.20 , pp. 1275-1278
    • D'Adamo, A.F.1    Smith, J.C.2    Woiler, C.3
  • 33
    • 0025923837 scopus 로고
    • Localized 1H NMR spectroscopy in Canavan's disease: a report of two cases
    • Austin S.J., Connelly A., Gadian D.G., et al. Localized 1H NMR spectroscopy in Canavan's disease: a report of two cases. Magn Reson Med 1991, 19:439-445.
    • (1991) Magn Reson Med , vol.19 , pp. 439-445
    • Austin, S.J.1    Connelly, A.2    Gadian, D.G.3
  • 34
    • 0027749707 scopus 로고
    • Multinuclear NMR studies on the energy metabolism of glial and neuronal cells
    • Brand A., Richter-Landsberg C., Leibfritz D. Multinuclear NMR studies on the energy metabolism of glial and neuronal cells. Dev Neurosci 1993, 15(3-5):289-298.
    • (1993) Dev Neurosci , vol.15 , Issue.3-5 , pp. 289-298
    • Brand, A.1    Richter-Landsberg, C.2    Leibfritz, D.3
  • 35
    • 0026633564 scopus 로고
    • Specific expression of N-acetylaspartate in neurons, oligodendrocyte- type-2 astrocyte progenitors, and immature oligodendrocytes invitro
    • Urenjak J., Williams S.R., Gadian D.G., et al. Specific expression of N-acetylaspartate in neurons, oligodendrocyte- type-2 astrocyte progenitors, and immature oligodendrocytes invitro. JNeurochem 1992, 59(1):55-61.
    • (1992) JNeurochem , vol.59 , Issue.1 , pp. 55-61
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3
  • 37
    • 33745266134 scopus 로고    scopus 로고
    • N-acetylaspartate as a reservoir for glutamate
    • Clark J.F., Doepke A., Filosa J.A., et al. N-acetylaspartate as a reservoir for glutamate. Med Hypotheses 2006, 67(3):506-512.
    • (2006) Med Hypotheses , vol.67 , Issue.3 , pp. 506-512
    • Clark, J.F.1    Doepke, A.2    Filosa, J.A.3
  • 38
    • 0024325294 scopus 로고
    • N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain
    • Birken D.L., Oldendorf W.H. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev 1989, 13(1):23-31.
    • (1989) Neurosci Biobehav Rev , vol.13 , Issue.1 , pp. 23-31
    • Birken, D.L.1    Oldendorf, W.H.2
  • 39
    • 0035072775 scopus 로고    scopus 로고
    • Absence of N-acetylaspartate in the human brain: impact on neurospectroscopy?
    • Martin E., Capone A., Schneider J., et al. Absence of N-acetylaspartate in the human brain: impact on neurospectroscopy?. Ann Neurol 2001, 49(4):518-521.
    • (2001) Ann Neurol , vol.49 , Issue.4 , pp. 518-521
    • Martin, E.1    Capone, A.2    Schneider, J.3
  • 40
    • 0033935979 scopus 로고    scopus 로고
    • Creatine and creatinine metabolism
    • Wyss M., Kaddurah-Daouk R. Creatine and creatinine metabolism. Physiol Rev 2000, 80(3):1107-1213.
    • (2000) Physiol Rev , vol.80 , Issue.3 , pp. 1107-1213
    • Wyss, M.1    Kaddurah-Daouk, R.2
  • 41
    • 0026147120 scopus 로고
    • Areview of chemical issues in 1H NMR spectroscopy: N-Acetyl-L-aspartate, creatine and choline
    • Miller B. Areview of chemical issues in 1H NMR spectroscopy: N-Acetyl-L-aspartate, creatine and choline. NMR Biomed 1991, 4:47-52.
    • (1991) NMR Biomed , vol.4 , pp. 47-52
    • Miller, B.1
  • 42
    • 27144492384 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research
    • Stork C., Renshaw P.F. Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research. Mol Psychiatry 2005, 10(10):900-919.
    • (2005) Mol Psychiatry , vol.10 , Issue.10 , pp. 900-919
    • Stork, C.1    Renshaw, P.F.2
  • 43
    • 0028001019 scopus 로고
    • Organic osmolytes in the brain of an infant with hypernatremia
    • Lee J., Arcinue E., Ross B. Organic osmolytes in the brain of an infant with hypernatremia. NEngl J Med 1994, 331:439-442.
    • (1994) NEngl J Med , vol.331 , pp. 439-442
    • Lee, J.1    Arcinue, E.2    Ross, B.3
  • 44
    • 0026145805 scopus 로고
    • Biochemical considerations in 1H spectroscopy. Glutamate and glutamine; Myo-inositol and related metabolites
    • Ross B.D. Biochemical considerations in 1H spectroscopy. Glutamate and glutamine; Myo-inositol and related metabolites. NMR Biomed 1991, 4:59-63.
    • (1991) NMR Biomed , vol.4 , pp. 59-63
    • Ross, B.D.1
  • 45
    • 0029609260 scopus 로고
    • Symbiosis between invivo and invitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain
    • Petroff O.A., Pleban L.A., Spencer D.D. Symbiosis between invivo and invitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain. Magn Reson Imaging 1995, 13(8):1197-1211.
    • (1995) Magn Reson Imaging , vol.13 , Issue.8 , pp. 1197-1211
    • Petroff, O.A.1    Pleban, L.A.2    Spencer, D.D.3
  • 46
    • 33747131017 scopus 로고    scopus 로고
    • Pitfalls in lactate measurements at 3T
    • Lange T., Dydak U., Roberts T.P., et al. Pitfalls in lactate measurements at 3T. AJNR Am J Neuroradiol 2006, 27(4):895-901.
    • (2006) AJNR Am J Neuroradiol , vol.27 , Issue.4 , pp. 895-901
    • Lange, T.1    Dydak, U.2    Roberts, T.P.3
  • 47
    • 0027451907 scopus 로고
    • Development of the human brain: invivo quantification of metabolite and water content with proton magnetic resonance spectroscopy
    • Kreis R., Ernst T., Ross B.D. Development of the human brain: invivo quantification of metabolite and water content with proton magnetic resonance spectroscopy. Magn Reson Med 1993, 30(4):424-437.
    • (1993) Magn Reson Med , vol.30 , Issue.4 , pp. 424-437
    • Kreis, R.1    Ernst, T.2    Ross, B.D.3
  • 48
    • 0031985750 scopus 로고    scopus 로고
    • Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS
    • Pouwels P.J., Frahm J. Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS. Magn Reson Med 1998, 39:53-60.
    • (1998) Magn Reson Med , vol.39 , pp. 53-60
    • Pouwels, P.J.1    Frahm, J.2
  • 49
    • 58549117914 scopus 로고    scopus 로고
    • Asystematic review of brain metabolite changes, measured with 1H magnetic resonance spectroscopy, in healthy aging
    • Haga K.K., Khor Y.P., Farrall A., et al. Asystematic review of brain metabolite changes, measured with 1H magnetic resonance spectroscopy, in healthy aging. Neurobiol Aging 2009, 30(3):353-363.
    • (2009) Neurobiol Aging , vol.30 , Issue.3 , pp. 353-363
    • Haga, K.K.1    Khor, Y.P.2    Farrall, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.