메뉴 건너뛰기




Volumn 8, Issue 8, 2013, Pages

HLA-DO as the Optimizer of Epitope Selection for MHC Class II Antigen Presentation

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA DM ANTIGEN; HLA DO ANTIGEN; HLA DR1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 84881319397     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071228     Document Type: Article
Times cited : (36)

References (70)
  • 1
    • 0025249197 scopus 로고
    • The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
    • Neefjes JJ, Stollorz V, Peters PJ, Geuze HJ, Ploegh HL, (1990) The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. Cell 61: 171-183.
    • (1990) Cell , vol.61 , pp. 171-183
    • Neefjes, J.J.1    Stollorz, V.2    Peters, P.J.3    Geuze, H.J.4    Ploegh, H.L.5
  • 2
    • 0026034448 scopus 로고
    • Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
    • Peters PJ, Neefjes JJ, Oorschot V, Ploegh HL, Geuze HJ, (1991) Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature 349: 669-676.
    • (1991) Nature , vol.349 , pp. 669-676
    • Peters, P.J.1    Neefjes, J.J.2    Oorschot, V.3    Ploegh, H.L.4    Geuze, H.J.5
  • 3
    • 0011720253 scopus 로고
    • Role for intracellular proteases in the processing and transport of class II HLA antigens
    • Blum JS, Cresswell P, (1988) Role for intracellular proteases in the processing and transport of class II HLA antigens. Proc Natl Acad Sci U S A 85: 3975-3979.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 3975-3979
    • Blum, J.S.1    Cresswell, P.2
  • 4
    • 0028313992 scopus 로고
    • Assembly, transport, and function of MHC class II molecules
    • Cresswell P, (1994) Assembly, transport, and function of MHC class II molecules. Annu Rev Immunol 12: 259-293.
    • (1994) Annu Rev Immunol , vol.12 , pp. 259-293
    • Cresswell, P.1
  • 5
    • 0025870669 scopus 로고
    • A role for peptide in determining MHC class II structure
    • Sadegh-Nasseri S, Germain RN, (1991) A role for peptide in determining MHC class II structure. Nature 353: 167-170.
    • (1991) Nature , vol.353 , pp. 167-170
    • Sadegh-Nasseri, S.1    Germain, R.N.2
  • 6
    • 0026584496 scopus 로고
    • How MHC class II molecules work: peptide-dependent completion of protein folding
    • Sadegh-Nasseri S, Germain RN, (1992) How MHC class II molecules work: peptide-dependent completion of protein folding. Immunol Today 13: 43-46.
    • (1992) Immunol Today , vol.13 , pp. 43-46
    • Sadegh-Nasseri, S.1    Germain, R.N.2
  • 7
    • 0024501330 scopus 로고
    • A kinetic intermediate in the reaction of an antigenic peptide and I-Ek
    • Sadegh-Nasseri S, McConnell HM, (1989) A kinetic intermediate in the reaction of an antigenic peptide and I-Ek. Nature 337: 274-276.
    • (1989) Nature , vol.337 , pp. 274-276
    • Sadegh-Nasseri, S.1    McConnell, H.M.2
  • 8
    • 0027941809 scopus 로고
    • MHC class II function preserved by low-affinity peptide interactions preceding stable binding
    • Sadegh-Nasseri S, Stern LJ, Wiley DC, Germain RN, (1994) MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature 370: 647-650.
    • (1994) Nature , vol.370 , pp. 647-650
    • Sadegh-Nasseri, S.1    Stern, L.J.2    Wiley, D.C.3    Germain, R.N.4
  • 9
    • 2142774531 scopus 로고
    • Peptide, invariant chain, or molecular aggregation preserves class II from functional inactivation
    • In: Humphreys RE, Pierce SK, editors, San Diego: Academic Press
    • Sadegh-Nasseri S (1994) Peptide, invariant chain, or molecular aggregation preserves class II from functional inactivation In: Humphreys RE, Pierce SK, editors. Antigen processing and presentation. San Diego: Academic Press. 170-187.
    • (1994) Antigen processing and presentation , pp. 170-187
    • Sadegh-Nasseri, S.1
  • 10
    • 0030806054 scopus 로고    scopus 로고
    • Antigen presentation by MHC class II molecules: invariant chain function, protein trafficking, and the molecular basis of diverse determinant capture
    • Castellino F, Zhong G, Germain RN, (1997) Antigen presentation by MHC class II molecules: invariant chain function, protein trafficking, and the molecular basis of diverse determinant capture. Hum Immunol 54: 159-169.
    • (1997) Hum Immunol , vol.54 , pp. 159-169
    • Castellino, F.1    Zhong, G.2    Germain, R.N.3
  • 11
    • 0028136262 scopus 로고
    • The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy
    • Romagnoli P, Germain RN, (1994) The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy. J Exp Med 180: 1107-1113.
    • (1994) J Exp Med , vol.180 , pp. 1107-1113
    • Romagnoli, P.1    Germain, R.N.2
  • 12
    • 0033120523 scopus 로고    scopus 로고
    • Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides
    • Natarajan SK, Assadi M, Sadegh-Nasseri S, (1999) Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides. J Immunol 162: 4030-4036.
    • (1999) J Immunol , vol.162 , pp. 4030-4036
    • Natarajan, S.K.1    Assadi, M.2    Sadegh-Nasseri, S.3
  • 13
    • 0034695675 scopus 로고    scopus 로고
    • Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1
    • Sato AK, Zarutskie JA, Rushe MM, Lomakin A, Natarajan SK, et al. (2000) Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1. J Biol Chem 275: 2165-2173.
    • (2000) J Biol Chem , vol.275 , pp. 2165-2173
    • Sato, A.K.1    Zarutskie, J.A.2    Rushe, M.M.3    Lomakin, A.4    Natarajan, S.K.5
  • 14
    • 0025056497 scopus 로고
    • Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes
    • Mellins E, Smith L, Arp B, Cotner T, Celis E, et al. (1990) Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes. Nature 343: 71-74.
    • (1990) Nature , vol.343 , pp. 71-74
    • Mellins, E.1    Smith, L.2    Arp, B.3    Cotner, T.4    Celis, E.5
  • 15
    • 0028518547 scopus 로고
    • Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells
    • Denzin LK, Robbins NF, Carboy-Newcomb C, Cresswell P, (1994) Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells. Immunity 1: 595-606.
    • (1994) Immunity , vol.1 , pp. 595-606
    • Denzin, L.K.1    Robbins, N.F.2    Carboy-Newcomb, C.3    Cresswell, P.4
  • 16
    • 0029945575 scopus 로고    scopus 로고
    • Antigen presentation and T cell development in H2-M-deficient mice
    • Fung-Leung WP, Surh CD, Liljedahl M, Pang J, Leturcq D, et al. (1996) Antigen presentation and T cell development in H2-M-deficient mice. Science 271: 1278-1281.
    • (1996) Science , vol.271 , pp. 1278-1281
    • Fung-Leung, W.P.1    Surh, C.D.2    Liljedahl, M.3    Pang, J.4    Leturcq, D.5
  • 17
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading
    • Denzin LK, Cresswell P, (1995) HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading. Cell 82: 155-165.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 18
    • 0029151368 scopus 로고
    • The intracellular transport of MHC class II molecules in the absence of HLA-DM
    • Green JM, DeMars R, Xu X, Pierce SK, (1995) The intracellular transport of MHC class II molecules in the absence of HLA-DM. J Immunol 155: 3759-3768.
    • (1995) J Immunol , vol.155 , pp. 3759-3768
    • Green, J.M.1    DeMars, R.2    Xu, X.3    Pierce, S.K.4
  • 19
    • 0030978530 scopus 로고    scopus 로고
    • HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH
    • Kropshofer H, Arndt SO, Moldenhauer G, Hammerling GJ, Vogt AB, (1997) HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH. Immunity 6: 293-302.
    • (1997) Immunity , vol.6 , pp. 293-302
    • Kropshofer, H.1    Arndt, S.O.2    Moldenhauer, G.3    Hammerling, G.J.4    Vogt, A.B.5
  • 21
    • 0030060377 scopus 로고    scopus 로고
    • Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
    • Miyazaki T, Wolf P, Tourne S, Waltzinger C, Dierich A, et al. (1996) Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell 84: 531-541.
    • (1996) Cell , vol.84 , pp. 531-541
    • Miyazaki, T.1    Wolf, P.2    Tourne, S.3    Waltzinger, C.4    Dierich, A.5
  • 22
    • 0030048126 scopus 로고    scopus 로고
    • H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
    • Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, et al. (1996) H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell 84: 543-550.
    • (1996) Cell , vol.84 , pp. 543-550
    • Martin, W.D.1    Hicks, G.G.2    Mendiratta, S.K.3    Leva, H.I.4    Ruley, H.E.5
  • 23
    • 0029824101 scopus 로고    scopus 로고
    • Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM
    • Weber DA, Evavold BD, Jensen PE, (1996) Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM. Science 274: 618-620.
    • (1996) Science , vol.274 , pp. 618-620
    • Weber, D.A.1    Evavold, B.D.2    Jensen, P.E.3
  • 24
    • 0030723313 scopus 로고    scopus 로고
    • Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH
    • Ullrich HJ, Doring K, Gruneberg U, Jahnig F, Trowsdale J, et al. (1997) Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH. Proc Natl Acad Sci U S A 94: 13163-13168.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13163-13168
    • Ullrich, H.J.1    Doring, K.2    Gruneberg, U.3    Jahnig, F.4    Trowsdale, J.5
  • 25
  • 26
    • 0034684671 scopus 로고    scopus 로고
    • HLA-DM recognizes the flexible conformation of major histocompatibility complex class II
    • Chou CL, Sadegh-Nasseri S, (2000) HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. J Exp Med 192: 1697-1706.
    • (2000) J Exp Med , vol.192 , pp. 1697-1706
    • Chou, C.L.1    Sadegh-Nasseri, S.2
  • 27
  • 28
    • 33846952190 scopus 로고    scopus 로고
    • HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes
    • Narayan K, Chou CL, Kim A, Hartman IZ, Dalai S, et al. (2007) HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes. Nat Immunol 8: 92-100.
    • (2007) Nat Immunol , vol.8 , pp. 92-100
    • Narayan, K.1    Chou, C.L.2    Kim, A.3    Hartman, I.Z.4    Dalai, S.5
  • 29
    • 84871595445 scopus 로고    scopus 로고
    • Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection
    • Pos W, Sethi DK, Call MJ, Schulze MS, Anders AK, et al. (2012) Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection. Cell 151: 1557-1568.
    • (2012) Cell , vol.151 , pp. 1557-1568
    • Pos, W.1    Sethi, D.K.2    Call, M.J.3    Schulze, M.S.4    Anders, A.K.5
  • 30
    • 78650306212 scopus 로고    scopus 로고
    • HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide
    • Anders AK, Call MJ, Schulze MS, Fowler KD, Schubert DA, et al. (2011) HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide. Nat Immunol 12: 54-61.
    • (2011) Nat Immunol , vol.12 , pp. 54-61
    • Anders, A.K.1    Call, M.J.2    Schulze, M.S.3    Fowler, K.D.4    Schubert, D.A.5
  • 31
    • 33644988716 scopus 로고    scopus 로고
    • Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex
    • Belov K, Deakin JE, Papenfuss AT, Baker ML, Melman SD, et al. (2006) Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex. PLoS biology 4: e46.
    • (2006) PLoS Biology , vol.4
    • Belov, K.1    Deakin, J.E.2    Papenfuss, A.T.3    Baker, M.L.4    Melman, S.D.5
  • 32
    • 33644845394 scopus 로고    scopus 로고
    • Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation
    • Hornell TM, Burster T, Jahnsen FL, Pashine A, Ochoa MT, et al. (2006) Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation. J Immunol 176: 3536-3547.
    • (2006) J Immunol , vol.176 , pp. 3536-3547
    • Hornell, T.M.1    Burster, T.2    Jahnsen, F.L.3    Pashine, A.4    Ochoa, M.T.5
  • 34
    • 33846542557 scopus 로고    scopus 로고
    • Expression patterns of H2-O in mouse B cells and dendritic cells correlate with cell function
    • Fallas JL, Yi W, Draghi NA, O'Rourke HM, Denzin LK, (2007) Expression patterns of H2-O in mouse B cells and dendritic cells correlate with cell function. J Immunol 178: 1488-1497.
    • (2007) J Immunol , vol.178 , pp. 1488-1497
    • Fallas, J.L.1    Yi, W.2    Draghi, N.A.3    O'Rourke, H.M.4    Denzin, L.K.5
  • 35
  • 36
    • 0033784580 scopus 로고    scopus 로고
    • Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice
    • Perraudeau M, Taylor PR, Stauss HJ, Lindstedt R, Bygrave AE, et al. (2000) Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice. Eur J Immunol 30: 2871-2880.
    • (2000) Eur J Immunol , vol.30 , pp. 2871-2880
    • Perraudeau, M.1    Taylor, P.R.2    Stauss, H.J.3    Lindstedt, R.4    Bygrave, A.E.5
  • 37
    • 0343238970 scopus 로고    scopus 로고
    • Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO
    • van Ham M, van Lith M, Lillemeier B, Tjin E, Gruneberg U, et al. (2000) Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J Exp Med 191: 1127-1136.
    • (2000) J Exp Med , vol.191 , pp. 1127-1136
    • van Ham, M.1    van Lith, M.2    Lillemeier, B.3    Tjin, E.4    Gruneberg, U.5
  • 38
    • 77950193442 scopus 로고    scopus 로고
    • Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence
    • Yi W, Seth NP, Martillotti T, Wucherpfennig KW, Sant'Angelo DB, et al. (2010) Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence. J Clin Invest 120: 1324-1336.
    • (2010) J Clin Invest , vol.120 , pp. 1324-1336
    • Yi, W.1    Seth, N.P.2    Martillotti, T.3    Wucherpfennig, K.W.4    Sant'Angelo, D.B.5
  • 39
    • 0031551492 scopus 로고    scopus 로고
    • Negative regulation by HLA-DO of MHC class II-restricted antigen processing
    • Denzin LK, Sant'Angelo DB, Hammond C, Surman MJ, Cresswell P, (1997) Negative regulation by HLA-DO of MHC class II-restricted antigen processing. Science 278: 106-109.
    • (1997) Science , vol.278 , pp. 106-109
    • Denzin, L.K.1    Sant'Angelo, D.B.2    Hammond, C.3    Surman, M.J.4    Cresswell, P.5
  • 40
    • 0032509943 scopus 로고    scopus 로고
    • Antigen processing: HLA-DO-a hitchhiking inhibitor of HLA-DM
    • Jensen PE, (1998) Antigen processing: HLA-DO-a hitchhiking inhibitor of HLA-DM. Curr Biol 8: R128-131.
    • (1998) Curr Biol , vol.8
    • Jensen, P.E.1
  • 41
    • 0032101695 scopus 로고    scopus 로고
    • A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules
    • Kropshofer H, Vogt AB, Thery C, Armandola EA, Li BC, et al. (1998) A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules. Embo J 17: 2971-2981.
    • (1998) Embo J , vol.17 , pp. 2971-2981
    • Kropshofer, H.1    Vogt, A.B.2    Thery, C.3    Armandola, E.A.4    Li, B.C.5
  • 42
    • 0037331965 scopus 로고    scopus 로고
    • Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes
    • Brocke P, Armandola E, Garbi N, Hammerling GJ, (2003) Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes. European journal of immunology 33: 411-421.
    • (2003) European Journal of Immunology , vol.33 , pp. 411-421
    • Brocke, P.1    Armandola, E.2    Garbi, N.3    Hammerling, G.J.4
  • 43
    • 0033559513 scopus 로고    scopus 로고
    • Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1
    • Natarajan SK, Stern LJ, Sadegh-Nasseri S, (1999) Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. J Immunol 162: 3463-3470.
    • (1999) J Immunol , vol.162 , pp. 3463-3470
    • Natarajan, S.K.1    Stern, L.J.2    Sadegh-Nasseri, S.3
  • 44
    • 78149357976 scopus 로고    scopus 로고
    • A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes
    • Hartman IZ, Kim A, Cotter RJ, Walter K, Dalai SK, et al. (2010) A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes. Nat Med 16: 1333-1340.
    • (2010) Nat Med , vol.16 , pp. 1333-1340
    • Hartman, I.Z.1    Kim, A.2    Cotter, R.J.3    Walter, K.4    Dalai, S.K.5
  • 45
    • 68749117718 scopus 로고    scopus 로고
    • HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1
    • Narayan K, Su KW, Chou CL, Khoruzhenko S, Sadegh-Nasseri S, (2009) HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1. Mol Immunol 46: 3157-3162.
    • (2009) Mol Immunol , vol.46 , pp. 3157-3162
    • Narayan, K.1    Su, K.W.2    Chou, C.L.3    Khoruzhenko, S.4    Sadegh-Nasseri, S.5
  • 46
    • 84879314960 scopus 로고    scopus 로고
    • Studying MHC Class II Peptide Loading and Editing In Vitro
    • In: Peter M. van Endert P, editor, Springer, Humana Press
    • Kim A, Ishizuka I, Hartman IZ, Poluektov Y, Narayan K, et al. (2013) Studying MHC Class II Peptide Loading and Editing In Vitro. In: Peter M. van Endert P, editor. Antigen Processing: Methods and Protocols: Springer, Humana Press. 447-460.
    • (2013) Antigen Processing: Methods and Protocols , pp. 447-460
    • Kim, A.1    Ishizuka, I.2    Hartman, I.Z.3    Poluektov, Y.4    Narayan, K.5
  • 48
    • 0029790517 scopus 로고    scopus 로고
    • HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport
    • Liljedahl M, Kuwana T, Fung-Leung WP, Jackson MR, Peterson PA, et al. (1996) HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport. Embo J 15: 4817-4824.
    • (1996) Embo J , vol.15 , pp. 4817-4824
    • Liljedahl, M.1    Kuwana, T.2    Fung-Leung, W.P.3    Jackson, M.R.4    Peterson, P.A.5
  • 49
    • 18144397513 scopus 로고    scopus 로고
    • A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM
    • Deshaies F, Brunet A, Diallo DA, Denzin LK, Samaan A, et al. (2005) A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM. Proc Natl Acad Sci U S A 102: 6443-6448.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 6443-6448
    • Deshaies, F.1    Brunet, A.2    Diallo, D.A.3    Denzin, L.K.4    Samaan, A.5
  • 50
    • 66549117520 scopus 로고    scopus 로고
    • Evidence for a human leucocyte antigen-DM-induced structural change in human leucocyte antigen-DObeta
    • Deshaies F, Diallo DA, Fortin JS, O'Rourke HM, Pezeshki AM, et al. (2009) Evidence for a human leucocyte antigen-DM-induced structural change in human leucocyte antigen-DObeta. Immunology 127: 408-417.
    • (2009) Immunology , vol.127 , pp. 408-417
    • Deshaies, F.1    Diallo, D.A.2    Fortin, J.S.3    O'Rourke, H.M.4    Pezeshki, A.M.5
  • 51
    • 0030903740 scopus 로고    scopus 로고
    • An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen
    • Rosloniec EF, Brand DD, Myers LK, Whittington KB, Gumanovskaya M, et al. (1997) An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen. J Exp Med 185: 1113-1122.
    • (1997) J Exp Med , vol.185 , pp. 1113-1122
    • Rosloniec, E.F.1    Brand, D.D.2    Myers, L.K.3    Whittington, K.B.4    Gumanovskaya, M.5
  • 52
    • 3242772752 scopus 로고    scopus 로고
    • Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation
    • Fallas JL, Tobin HM, Lou O, Guo D, Sant'Angelo DB, et al. (2004) Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation. J Immunol 173: 1549-1560.
    • (2004) J Immunol , vol.173 , pp. 1549-1560
    • Fallas, J.L.1    Tobin, H.M.2    Lou, O.3    Guo, D.4    Sant'Angelo, D.B.5
  • 56
    • 84867591997 scopus 로고    scopus 로고
    • The Toxoplasma gondii peptide AS15 elicits CD4 T cells that can control parasite burden
    • Grover HS, Blanchard N, Gonzalez F, Chan S, Robey EA, et al. (2012) The Toxoplasma gondii peptide AS15 elicits CD4 T cells that can control parasite burden. Infection and immunity 80: 3279-3288.
    • (2012) Infection and Immunity , vol.80 , pp. 3279-3288
    • Grover, H.S.1    Blanchard, N.2    Gonzalez, F.3    Chan, S.4    Robey, E.A.5
  • 58
    • 84868139454 scopus 로고    scopus 로고
    • Endogenous HLA class II epitopes that are immunogenic in vivo show distinct behavior toward HLA-DM and its natural inhibitor HLA-DO
    • Kremer AN, van der Meijden ED, Honders MW, Goeman JJ, Wiertz EJ, et al. (2012) Endogenous HLA class II epitopes that are immunogenic in vivo show distinct behavior toward HLA-DM and its natural inhibitor HLA-DO. Blood 120: 3246-3255.
    • (2012) Blood , vol.120 , pp. 3246-3255
    • Kremer, A.N.1    van der Meijden, E.D.2    Honders, M.W.3    Goeman, J.J.4    Wiertz, E.J.5
  • 59
    • 84857040681 scopus 로고    scopus 로고
    • The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway
    • Schulze MS, Wucherpfennig KW, (2012) The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway. Current opinion in immunology 24: 105-111.
    • (2012) Current Opinion in Immunology , vol.24 , pp. 105-111
    • Schulze, M.S.1    Wucherpfennig, K.W.2
  • 60
    • 1842633890 scopus 로고    scopus 로고
    • T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM
    • Pu Z, Lovitch SB, Bikoff EK, Unanue ER, (2004) T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. Immunity 20: 467-476.
    • (2004) Immunity , vol.20 , pp. 467-476
    • Pu, Z.1    Lovitch, S.B.2    Bikoff, E.K.3    Unanue, E.R.4
  • 61
    • 1642495746 scopus 로고    scopus 로고
    • Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain
    • Stratikos E, Wiley DC, Stern LJ, (2004) Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain. J Immunol 172: 1109-1117.
    • (2004) J Immunol , vol.172 , pp. 1109-1117
    • Stratikos, E.1    Wiley, D.C.2    Stern, L.J.3
  • 62
    • 14844314502 scopus 로고    scopus 로고
    • Conservation of MHC class II DOA sequences among carnivores
    • Soll SJ, Stewart BS, Lehman N, (2005) Conservation of MHC class II DOA sequences among carnivores. Tissue Antigens 65: 283-286.
    • (2005) Tissue Antigens , vol.65 , pp. 283-286
    • Soll, S.J.1    Stewart, B.S.2    Lehman, N.3
  • 63
    • 78049276727 scopus 로고    scopus 로고
    • H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers
    • Draghi NA, Denzin LK, (2010) H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers. Proc Natl Acad Sci U S A 107: 16607-16612.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 16607-16612
    • Draghi, N.A.1    Denzin, L.K.2
  • 65
    • 58149337062 scopus 로고    scopus 로고
    • Memory CD8 T-cell compartment grows in size with immunological experience
    • Vezys V, Yates A, Casey KA, Lanier G, Ahmed R, et al. (2009) Memory CD8 T-cell compartment grows in size with immunological experience. Nature 457: 196-199.
    • (2009) Nature , vol.457 , pp. 196-199
    • Vezys, V.1    Yates, A.2    Casey, K.A.3    Lanier, G.4    Ahmed, R.5
  • 69
    • 84878289907 scopus 로고    scopus 로고
    • Elimination of self-reactive T cells in the thymus: a timeline for negative selection
    • Dzhagalov IL, Chen KG, Herzmark P, Robey EA, (2013) Elimination of self-reactive T cells in the thymus: a timeline for negative selection. PLoS biology 11: e1001566.
    • (2013) PLoS Biology , vol.11
    • Dzhagalov, I.L.1    Chen, K.G.2    Herzmark, P.3    Robey, E.A.4
  • 70
    • 75049085806 scopus 로고    scopus 로고
    • Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population
    • Reynolds RJ, Kelley JM, Hughes LB, Yi N, Bridges SL Jr, (2010) Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population. Genes and immunity 11: 94-97.
    • (2010) Genes and Immunity , vol.11 , pp. 94-97
    • Reynolds, R.J.1    Kelley, J.M.2    Hughes, L.B.3    Yi, N.4    Bridges Jr., S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.