Antigen processing: HLA-DO - A hitchhiking inhibitor of HLA-DM

Current Biology

Volumn 8, Issue 4, 1998, Pages

  Jensen, Peter E ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032509943     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(98)70988-1     Document Type: Article

References (14)

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3. Sherman MA, Weber DA, Jensen PA: DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity 1995, 3:197-205.
4. Vogt AB, Kropshofer H, Moldenhauer G, Hammerling GJ: Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM. Proc Natl Acad Sci USA 1996, 93:9724-9729.
5. Weber DA, Evavold BD, Jensen PE: Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM. Science 1996, 274:618-620.
6. Liljedahl M, Kuwana T, Fung-Leung WP, Jackson MR, Peterson PA, Karlsson L: HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport. EMBO J 1996, 15:4817-4824.
7. Denzin LK, Sant'Angelo DB, Hammond C, Surman MJ, Cresswell P: Negative regulation by HLA-DO of MHC class II-restricted antigen processing. Science 1997, 278:106-109.
8. van Ham SM, Tjin EPM, Lillemeier BF, Gruneberg U, van Meijgaarden KE, Pastoors L, Verwoerd D, Tulp A, Canas B, Rahman D, et al.: HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. Curr Biol 1997, 7:950-957.
9. Karlsson L, Surh CD, Sprent J, Peterson PA: A novel class II MHC molecule with unusual tissue distribution. Nature 1991, 351: 485-488.
10. Karlsson L, Peterson PA: The alpha chain gene of H-2O has an unexpected location in the major histocompatibility complex. J Exp Med 1992, 176:477-483.
11. Fuchs EJ, Matzinger P: B cells turn off virgin but not memory T cells. Science 1992, 258:1156-1159.
12. Eynon EE, Parker DC: Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J Exp Med 1992, 175:131-138.
13. Katz JF, Stebbins C, Appella E, Sant AJ: Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules. J Exp Med 1996, 184:1747-1753.
14. Douek DC, Altmann DM: HLA-DO is an intracellular class II molecule with distinctive thymic expression. Int Immunol 1997, 9:355-364.