Expression patterns of H2-O in mouse B cells and dendritic cells correlate with cell function

Journal of Immunology

Volumn 178, Issue 3, 2007, Pages 1488-1497

  Fallas, Jennifer L ^a   Yi, Woelsung ^b   Draghi, Nicole A ^a   O'Rourke, Helen M ^b   Denzin, Lisa K ^a,b  

^a Weill Cornell Graduate School of Biomedical Sciences   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLASS II ASSOCIATED INVARIANT CHAIN PEPTIDE; H2 M ANTIGEN; H2 O ANTIGEN; HLA DO ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; ENDOSOME; GERMINAL CENTER; IMMUNE RESPONSE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL;

EID: 33846542557     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.3.1488     Document Type: Article

References (73)

1. Busch, R., R. C. Doebele, N. S. Patil, A. Pashine, and E. D. Mellins. 2000. Accessory molecules for MHC class II peptide loading. Curr. Opin. Immunol. 12: 99-106.
2. Hiltbold, E. M., and P. A. Roche. 2002. Trafficking of MHC class II molecules in the late secretory pathway. Curr. Opin. Immunol. 14: 30-35.
3. Watts, C. 2004. The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules. Nat. Immunol. 5: 685-692.
4. Peters, P. J., J. J. Neefjes, V. Oorschot, H. L. Ploegh, and H. J. Geuze. 1991. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature 349: 669-676.
5. Tulp, A., D. Verwoerd, B. Dobberstein, H. L. Ploegh, and J. Pieters. 1994. Isolation and characterization of the intracellular MHC class II compartment. Nature 369: 120-126.
6. Honey, K., and A. Y. Rudensky. 2003. Lysosomal cysteine proteases regulate antigen presentation. Nat. Rev. Immunol. 3: 472-482.
7. Wolf, P. R., and H. L. Ploegh. 1995. How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway. Annu. Rev. Cell. Dev. Biol. 11: 267-306.
8. Sherman, M. A., D. A. Weber, and P. E. Jensen. 1995. DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity 3: 197-205.
9. Denzin, L. K., and P. Cresswell. 1995. HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell 82: 155-165.
10. Sloan, V. S., P. Cameron, G. Porter, M. Gammon, M. Amaya, E. Mellins, and D. M. Zaller. 1995. Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375: 802-806.
11. Denzin, L. K., C. Hammond, and P. Cresswell. 1996. HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J. Exp. Med. 184: 2153-2165.
12. Kropshofer, H., S. O. Arndt, G. Moldenhauer, G. J. Hammerling, and A. B. Vogt. 1997. HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH. Immunity 6: 293-302.
13. Kropshofer, H., A. B. Vogt, G. Moldenhauer, J. Hammer, J. S. Blum, and G. J. E. J. Hammerling. 1996. Editing of the HLA-DR-peptide repertoire by HLA-DM. EMBO J. 15: 6144-6154.
14. van Ham, S. M., U. Gruneberg, G. Malcherek, I. Broker, A. Melms, and J. Trowsdale. 1996. Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs. J. Exp. Med. 184: 2019-2024.
15. Weber, D. A., B. D. Evavold, and P. E. Jensen. 1996. Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM. Science 274: 618-620.
16. Liljedahl, M., T. Kuwana, W. P. Fung-Leung, M. R. Jackson, P. A. Peterson, and L. Karlsson. 1996. HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport. EMBO J. 15: 4817-4824.
17. Karlsson, L., C. D. Surh, J. Sprent, and P. A. Peterson. 1991. A novel class H MHC molecule with unusual tissue distribution. Nature 351: 485-488.
18. Liljedahl, M., O. Winqvist, C. D. Surh, P. Wong, K. Ngo, L. Teyton, P. A. Peterson, A. Brunmark, A. Y. Rudensky, W. P. Fung-Leung, and L. Karlsson. 1998. Altered antigen presentation in mice lacking H2-O. Immunity 8: 233-243.
19. Chen, X., O. Laur, T. Kambayashi, S. Li, R. A. Bray, D. A. Weber, L. Karlsson, and P. E. Jensen. 2002. Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development. J. Exp. Med. 195: 1053-1062.
20. Fallas, J. L., H. M. Tobin, O. Lou, D. Quo, D. B. Sant'Angelo, and L. K. Denzin. 2004. Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation. J. Immunol. 173: 1549-1560.
21. Douek, D. C., and D. M. Altmann. 1997. HLA-DO is an intracellular class II molecule with distinctive thymic expression. Int. Immunol. 9: 355-364.
22. Surh, C. D., E. K. Gao, H. Kosaka, D. Lo, C. Ahn, D. B. Murphy, L. Karlsson, P. Peterson, and J. Sprent. 1992. Two subsets of epithelial cells in the thymic medulla. J. Exp. Med. 176: 495-505.
23. Hornell, T. M., T. Burster, F. L. Jahnsen, A. Pashine, M. T. Ochoa, J. J. Harding, C. Macaubas, A. W. Lee, R. L. Modlin, and E. D. Mellins. 2006. Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation. J. Immunol. 176: 3536-3547.
24. Chen, X., L. M. Reed-Loisel, L. Karlsson, and P. E. Jensen. 2006. H2-O expression in primary dendritic cells. J. Immunol. 176: 3548-3556.
25. Denzin, L. K., D. B. Sant'Angelo, C. Hammond, M. J. Surman, and P. Cresswell. 1997. Negative regulation by HLA-DO of MHC class II-restricted antigen processing. Science 278: 106-109.
26. Brocke, P., E. Armandola, N. Garbi, and G. J. Hammerling. 2003. Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes. Eur. J. Immunol. 33: 411-421.
27. van Ham, M., M. van Lith, B. Lillemeier, E. Tjin, U. Gruneberg, D. Rahman, L. Pastoors, K. van Meijgaarden, C. Roucard, J. Trowsdale, et al. 2000. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J. Exp. Med. 191: 1127-1136.
28. Glazier, K. S., S. B. Hake, H. M. Tobin, A. Chadburn, E. J. Schattner, and L. K. Denzin. 2002. Germinal center B cells regulate their capability to present antigen by modulation of HLA-DO. J. Exp. Med. 195: 1063-1069.
29. van Ham, S. M., E. P. Tjin, B. F. Lillemeier, U. Gruneberg, K. E. van Meijgaarden, L. Pastoors, D. Verwoerd, A. Tulp, B. Canas, D. Rahman, et al. 1997. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. Curr. Biol. 7: 950-957.
30. Qi, L., and S. Ostrand-Rosenberg. 2001. H2-O inhibits presentation of bacterial superantigens, but not endogenous self antigens. J. Immunol. 167: 1371-1378.
31. Alfonso, C., G. S. Williams, J. O. Han, J. A. Westberg, O. Winqvist, and L. Karlsson. 2003. Analysis of H2-O influence on antigen presentation by B cells. J. Immunol. 171: 2331-2337.
32. Alfonso, C., G. S. Williams, and L. Karlsson. 2003. H2-O influence on antigen presentation in H2-E-expressing mice. Eur. J. Immunol. 33: 2014-2021.
33. Kropshofer, H., A. B. Vogt, C. Thery, E. A. Armandola, B. C. Li, G. Moldenhauer, S. Amigorena, and G. J. Hammerling. 1998. A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules. EMBO J. 17:2971-2981.
34. Denzin, L. K., J. L. Fallas, M. Prendes, and W. Yi. 2005. Right place, right time, right peptide: DO keeps DM focused. Immunol. Rev. 207: 279-292.
35. Perraudeau, M., P. R. Taylor, H. J. Stauss, R. Lindstedt, A. E. Bygrave, D. J. Pappin, S. Ellmerich, A. Whitten, D. Rahman, B. Canas, et al. 2000. Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice. Eur. J. Immunol. 30: 2871-2880.
36. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176: 1693-1702.
37. Inaba, K., S. Turley, T. Iyoda, F. Yamaide, S. Shimoyama, C. Reis e Sousa, R. N. Germain, I. Mellman, and R. M. Steinman. 2000. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J. Exp. Med. 191: 927-936.
38. Sant'Angelo, D. B., P. Cresswell, C. A. Janeway, Jr., and L. K. Denzin. 2001. Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers. Proc. Natl. Acad. Sci. USA 98: 6824-6829.
39. Gordon, K. M., L. Duckett, B. Daul, and H. T. Petrie. 2003. A simple method for detecting up to five immunofluorescent parameters together with DNA staining for cell cycle or viability on a benchtop flow cytometer. J. Immunol. Methods 275: 113-121.
40. Grubin, C. E., S. Kovats, P. deRoos, and A. Y. Rudensky. 1997. Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity 7: 197-208.
41. Dongre, A. R., S. Kovats, P. deRoos, A. L. McCormack, T. Nakagawa, V. Paharkova-Vatchkova, J. Eng, H. Caldwell, J. R. Yates 3rd, and A. Y. Rudensky. 2001. In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses. Eur. J. Immunol. 31: 1485-1494.
42. Allen, P. M., and E. R. Unanue. 1984. Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas. J. Immunol. 132: 1077-1079.
43. Sant'Angelo, D. B., and C. A. Janeway, Jr. 2002. Negative selection of thymocytes expressing the D10 TCR. Proc. Natl. Acad. Sci. USA 99: 6931-6936.
44. + T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341: 746-749.
45. Kawai, K., N. H. Tsuno, M. Matsuhashi, I. Kitayama, T. Osada, J. Yamada, T. Tsuchiya, S. Yoneyama, T. Watanabe, K. Takahashi, and H. Nagawa. 2005. CD11b-mediated migratory property of peripheral blood B cells. J. Allergy Clin. Immunol. 116: 192-197.
46. Carsetti, R., M. M. Rosado, and H. Wardmann. 2004. Peripheral development of B cells in mouse and man. Immunol. Rev. 197: 179-191.
47. Hardy, R. R., and K. Hayakawa. 2001. B cell development pathways. Annu. Rev. Immunol. 19: 595-621.
48. Lam, K. P., and A. M. Stall. 1994. Major histocompatibility complex class II expression distinguishes two distinct B cell developmental pathways during ontogeny. J. Exp. Med. 180: 507-516.
49. Chalouni, C., J. Banchereau, A. B. Vogt, V. Pascual, and J. Davoust. 2003. Human germinal center B cells differ from naive and memory B cells by their aggregated MHC class II-rich compartments lacking HLA-DO. Int. Immunol. 15: 457-466.
50. Shih, T. A., E. Meffre, M. Roederer, and M. C. Nussenzweig. 2002. Role of BCR affinity in T cell dependent antibody responses in vivo. Nat. Immunol. 3: 570-575.
51. Hammond, C., L. K. Denzin, M. Pan, J. M. Griffith, H. J. Geuze, and P. Cresswell. 1998. The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules. J. Immunol. 161: 3282-3291.
52. Itano, A. A., S. J. McSorley, R. L. Reinhardt, B. D. Ehst, E. Ingulli, A. Y. Rudensky, and M. K. Jenkins. 2003. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity 19: 47-57.
53. Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
54. Steinman, R. M., and K. Inaba. 1999. Myeloid dendritic cells. J. Leukocyte Biol. 66: 205-208.
55. Chung, J. B., A. D. Wells, S. Adler, A. Jacob, L. A. Turka, and J. G. Monroe. 2003. Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness. J. Immunol. 171: 1758-1767.
56. Casamayor-Palleja, M., A. Gulbranson-Judge, and I. C. MacLennan. 1997. T cells in the selection of germinal center B cells. Chem. Immunol. 67: 27-44.
57. Gondre-Lewis, T. A., A. E. Moquin, and J. R. Drake. 2001. Prolonged antigen persistence within nonterminal late endocytic compartments of antigen-specific B lymphocytes. J. Immunol. 166: 6657-6664.
58. Deshaies, F., A. Brunet, D. A. Diallo, L. K. Denzin, A. Samaan, and J. Thibodeau. 2005. A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM. Proc. Natl. Acad. Sci. USA 102: 6443-6448.
59. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
60. Itano, A. A., and M. K. Jenkins. 2003. Antigen presentation to naive CD4 T cells in the lymph node. Nat. Immunol. 4: 733-739.
61. + dendritic cells expressing indoleamine 2,3-dioxygenase. J. Immunol. 167: 708-714.
62. Suss, G., and K. Shortman. 1996. A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis. J. Exp. Med. 183: 1789-1796.
63. Watts, C. 1997. Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol. 15: 821-850.
64. Mellman, I., and R. M. Steinman. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106: 255-258.
65. Engering, A. J., M. Cella, D. Fluitsma, M. Brockhaus, E. C. Hoefsmit, A. Lanzavecchia, and J. Pieters. 1997. The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells. Eur. J. Immunol. 27: 2417-2425.
66. Engering, A. J., M. Cella, D. M. Fluitsma, E. C. Hoefsmit, A. Lanzavecchia, and J. Pieters. 1997. Mannose receptor mediated antigen uptake and presentation in human dendritic cells. Adv. Exp. Med. Biol. 417: 183-187.
67. Merck, E., C. Gaillard, D. M. Gorman, F. Montero-Julian, I. Durand, S. M. Zurawski, C. Menetrier-Caux, G. Carra, S. Lebecque, G. Trinchieri, and E. E. Bates. 2004. OSCAR is an FcRγ-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Blood 104: 1386-1395.
68. Engering, A., T. B. Geijtenbeek, S. J. van Vliet, M. Wijers, E. van Liempt, N. Demaurex, A. Lanzavecchia, J. Fransen, C. G. Figdor, V. Piguet, and Y. van Kooyk. 2002, The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J. Immunol. 168: 2118-2126.
69. Jiang, W., W. J. Swiggard, C. Heufler, M. Peng, A. Mirza, R. M. Steinman, and M. C. Nussenzweig. 1995. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375: 151-155.
70. Mahnke, K., M. Guo, S. Lee, H. Sepulveda, S. L. Swain, M. Nussenzweig, and R. M. Steinman. 2000. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J. Cell Biol. 151: 673-684.
71. Pierre, P., S. J. Turley, E. Gatti, M. Hull, J. Meltzer, A. Mirza, K. Inaba, R. M. Steinman, and I. Mellman. 1997. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 388: 787-792.
72. Lankar, D., H. Vincent-Schneider, V. Briken, T. Yokozeki, G. Raposo, and C. Bonnerot. 2002. Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J. Exp. Med. 195: 461-472.
73. Pierre, P., and I. Mellman. 1998. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells. Cell 93: 1135-1145.